• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.9 no.6
• /
• pp.1830-1837
• /
• 2008

The growth of an information and knowledge based society has changed the base of education from institution-based to a learner-based system. This indicates that the educational purpose and individual characters of the learners are the primary factors for the educational success. In the information and knowledge based society, the Cyber University is a representative example of the new educational paradigm with its online communities, multi-media based education and communication among the learners. The sample of study was 1620 students of a leading cyber university in Seoul, Korea. One of the results in this study showed that satisfaction levels of learning and education do not have significant relationship with age or employment. Rather the lowering level of satisfaction after sufficient adaptation period of cyber education was raised as rising problem.

• Journal of Pharmacopuncture
• /
• v.18 no.2
• /
• pp.67-75
• /
• 2015

Objectives: This study was carried out to analyze the single-dose toxicity of ShinYangHur (SYH) herbal acupuncture injected into the muscles of Sprague-Dawley (SD) rats. Methods: The SYH herbal acupuncture was made in a clean room at the Korean Pharmacopuncture Institute (KPI, Korea-Good Manufacturing Practice, K-GMP). After the mixing process with sterile distilled water, the pH was controlled to between 7.0 and 7.5. Then, NaCl was added to make a 0.9% isotonic solution by using sterilized equipment. All experiments were conducted at Biotoxtech, an institution authorized to perform non clinical studies under the regulations of Good Laboratory Practice (GLP). SD rats were chosen for the pilot study. Doses of SYH herbal acupuncture, 0.25, 0.5, and 1.0 mL, were administered to the experimental groups, and a dose of normal saline solution, 1.0 mL, was administered to the control group. This study was conducted under the approval of the Institutional Animal Ethics Committee. Results: No deaths or abnormalities occurred in any of the four groups. No significant changes in weight, hematological parameters or clinical chemistry between the control group and the experimental groups were observed. To check for abnormalities in organs and tissues, we used microscopy was used to examine representative histological sections of each specified organ; the results showed no significant differences in any of the organs or tissues. Conclusion: The above outcomes suggest that treatment with SYH herbal acupuncture is relatively safe. Further studies on this subject are needed to yield more concrete evidence.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.34 no.2
• /
• pp.21-37
• /
• 2021

Objectives : Allergic rhinitis(AR) is a common chronic disease that accounts for 10-40% of the world's population. This study aims to analyze the status of claims, prevalence, and medical utilization of allergic rhinitis patients using representative patients sample data. Methods : This study used the National Patients Sample(HIRA-NPS) of the Health Insurance Review and Assessment Service for 7 years(2010-2016). And we defined AR patients as all statements including J30 or a subcategory of J30 as the main disease, using the Korean Standard Classification of Diseases(KCD-7). The trend of AR patients by year was divided into Western medicine(WM) and Korean medicine(KM), and analyzed by subgroup analysis such as inpatient/outpatient, gender, age, insurance type, and care institution. Results : Patients with AR were mainly claimed for first sub diagnosis in WM and major diagnosis in KM, and the number of claims increased about 1.3 times and 1.4 times compared to 2010 in WM and KM, respectively. In addition, the total annual medical expenses in 2016 increased 1.3 times and 1.7 times compared to 2010, respectively. Conclusions : Both WM and KM are showing a steadily increasing trend in medical use due to allergic rhinitis. Further research is needed by considering genetic and environmental factors and individual characteristics, and linking with additional data.

• Journal of the Korean Society for information Management
• /
• v.37 no.4
• /
• pp.27-60
• /
• 2020

Sejong City Library information services and programs proposed in this study are proposed by combining cases of local representative libraries and overseas libraries. As a feature of the proposal, first, various information services that can be provided by the Sejong City Library are proposed by area, by user, by data type, by media, by partner institution, etc. Second, by reinforcing user programs for each life cycle, various reading programs by age and interest, such as reading discussion, reading experience, and reading events, are provided. Reinforce user-based programs that reflect the characteristics of Sejong City's population, such as adult, child, and family programs. Third, secure and utilize maker space space. Fourth, the reading program developed by the Sejong City Library is promoted and shared in cooperation with local libraries. Fifth, induce participation of local residents in Sejong City, volunteer activities and talent donation. Sixth, propose library information services using library websites and social media, and develop channels for mutual cooperation with users.

• Journal of Communication Design
• /
• v.62
• /
• pp.96-104
• /
• 2018

Jinling University during the Republic of China (1912-1949) is the most representative academic institution in film education and filmscience, film production, film distribution and many other aspects. Although Jinling University had not yet formed an independent animation discipline, the opening of its animation curriculum, theoretical research, and the practice and production of animation have played an important historical role in the development of Chinese animation and are the beginning of China's animation education. This study investigates Jinling University comprehensively and systematically reviews the forms of animation education. At the same time, macroscopical education and microcosmic education concepts are used to analyze the social context of the Republic of China of discipline construction and external education concept at that time. It sketches the historical clues of the development of animation education in Jinling University in the Republic of China, and lays the foundation for further studying animation education in the Republic of China in theory.

• Journal of English Language & Literature
• /
• v.54 no.1
• /
• pp.77-105
• /
• 2008

Even though Paule Marshall and Ishmael Reed have differences of gender, generation, and literary techniques, they share common points in dealing with cultural conflicts and racial discrimination in the United States as Afro-American Writers. As black minority writers, Marshall and Reed write out of a perspective of forced immigrant/fragmentary native consciousness. The purpose of this paper is to investigate the protagonist's reaction to racial prejudice, different cultures and their attempts to reconcile and to coexist with other races and their culture in these writers' representative works. Marshall's uniqueness as a contemporary black female artist stems from her ability to write from the three levels, that is, African American and Caribbean black. So, Marshall's Brown Girl, Brownstones represents an attempt to identify, analyze, and resolve the conflict between cultural loss/displacement and cultural domination/hegemony. Reed's Japanes by Spring offers a blistering attack upon the various cultural and racial factions of the academy and the bankrupt value systems in America. Reed's depiction of Jack London College's existing racial problems-later compounded by the cultural dilemmas that accompany the Japanese occupation of the institution-reveals his interest in highlighting the ways in which any monoculturalist ideology ultimately results in racist and culturally exclusive policies. Marshall's and Reed's novels provide opportunities for reader to explore various manifestations of intercultual and interethnic dynamics. They present the possibility of reconciliation and coexistence between different race and ethnic cultures through asserting a cultural hybridity and multiculturalism.

• Journal of Ginseng Research
• /
• v.46 no.2
• /
• pp.266-274
• /
• 2022

Colon cancer, the third most frequent occurred cancer, has high mortality and extremely poor prognosis. Ginsenoside, the active components of traditional Chinese herbal medicine Panax ginseng, exerts antitumor effect in various cancers, including colon cancer. However, the detailed molecular mechanism of Ginsenoside in the tumor suppression have not been fully elucidated. Here, we chose the representative ginsenoside Rg3 and reported for the first time that Rg3 induces mitophagy in human colon cancer cells, which is responsible for its anticancer effect. Rg3 treatment leads to mitochondria damage and the formation of mitophagosome; when autophagy is inhibited, the clearance of damaged mitochondria can be reversed. Next, our results showed that Rg3 treatment activates the PINK1-Parkin signaling pathway and recruits Parkin and ubiquitin proteins to mitochondria to induce mitophagy. GO analysis of Parkin targets showed that Parkin interacts with a large number of mitochondrial proteins and regulates the molecular function of mitochondria. The cellular energy metabolism enzyme GAPDH is validated as a novel substrate of Parkin, which is ubiquitinated by Parkin. Moreover, GAPDH participates in the Rg3-induced mitophagy and regulates the translocation of Parkin to mitochondria. Functionally, Rg3 exerts the inhibitory effect through regulating the nonglycolytic activity of GAPDH, which could be associated with the cellular oxidative stress. Thus, our results revealed GAPDH ubiquitination by Parkin as a crucial mechanism for mitophagy induction that contributes to the tumor-suppressive function of ginsenoside, which could be a novel treatment strategy for colon cancer.

• Industry Promotion Research
• /
• v.8 no.4
• /
• pp.177-186
• /
• 2023

Modern society is operated based on the internet, wireless networks, and digital devices to the extent that it is called a digital society. In particular, as most of financial transactions, information movement, and commercial activities are based online, various social problems and side effects related to this are increasing rapidly. Representative examples include industrial espionage activities and leakage of industrial technology, and social problems such as illegal goods trade such as drugs using online and online gambling are increasing to a serious level. These digital-based social problems cannot be solved only by the activities and capabilities of judicial institutions such as police and prosecutors. Now that the private investigation market is open, active intervention using them is necessary. To this end, it is necessary to actively cultivate private investigator's ability to investigate and collect evidence in relation to digital social and criminal problems. In addition, each private investigation education institution or association should actively invest and research this.

• Journal of Pharmacopuncture
• /
• v.19 no.4
• /
• pp.350-358
• /
• 2016

Objectives: This study was carried out to analyze the single dose toxicity of ShinEumHur (SEH) pharmacopuncture injected into the muscles of Sprague-Dawley rats. Methods: The SEH pharmacopuncture was made in a clean room at the Korean Pharmacopuncture Institute (K-GMP). After the mixing process with sterile distilled water had been completed, the pH was controlled to between 7.0 and 7.5. All experiments were conducted at Biotoxtech, an institution authorized to perform non-clinical studies under the Good Laboratory Practice (GLP) regulations. Sprague-Dawley rats were chosen for the pilot study. Doses of SEH pharmacopuncture, 0.25, 0.5 and 1.0 mL, were administered to the experimental groups, and a dose of normal saline solution, 1.0 mL, was administered to the control group. We examined the survival rate, weights, clinical signs, mean hematology parameters, mean clinical chemistry, necropsy and histopathological findings. This study was conducted under the approval of the Institutional Animal Ethics Committee. Results: No deaths or abnormalities occurred in any of the four groups. No significant changes in weight, hematological parameters or clinical chemistry between the control group and the experimental groups were observed. To check for abnormalities in organs and tissues, we used microscopy to examine representative histological sections of each specified organ; the results showed no significant differences in any of the organs or tissues. Conclusion: The above findings suggest that treatment with SEH pharmacopuncture is relatively safe. Further studies on this subject are needed to yield more concrete evidence.

• Journal of the Korea Society of Computer and Information
• /
• v.25 no.7
• /
• pp.183-191
• /
• 2020

The purpose of this study is to objectively analyze the trend of media articles related to the 'high school credit system' (2017~2019: 3 years), which has become the biggest concern among Korean education policies, through BIGKinds, a news data big data analysis service for media companies. The main research methodologies were BIGKinds system's specific search term news search, news trend analysis, keyword extraction and wordcloud implementation, network analysis and network picture presentation. The research results are as follows; First, the number of articles related to the high school credit system that appeared in major media outlets in Korea for 3 years from 2017 to 2019 was 3,649. The number of articles was sharply increased at a certain point about 4 times, based on the government's announcement of related policies. It showed an increasing news trend. Second, the top 20 keywords that emerged from the press articles related to the high school credit system for 3 years of analysis were presented, and it was confirmed that the keyword change by year appeared. Third, the network of media articles related to the high school credit system was visualized and presented in different ways by person, institution, and keyword. The results of this study confirmed that the high school credit system education policy was adopted as the representative education policy of the Moon Jae-in government, and is proceeding in the policy decision stage and policy implementation stage.