• Journal of Preventive Medicine and Public Health
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• 제46권5호
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• pp.213-225
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• 2013

Objectives: The aim of this study was to evaluate the association between Agent Orange exposure and self-reported diseases in Korean Vietnam veterans. Methods: A postal survey of 114 562 Vietnam veterans was conducted. The perceived exposure to Agent Orange was assessed by a 6-item questionnaire. Two proximity-based Agent Orange exposure indices were constructed using division/brigade-level and battalion/ company-level unit information. Adjusted odds ratios (ORs) for age and other confounders were calculated using a logistic regression model. Results: The prevalence of all self-reported diseases showed monotonically increasing trends as the levels of perceived self-reported exposure increased. The ORs for colon cancer (OR, 1.13), leukemia (OR, 1.56), hypertension (OR, 1.03), peripheral vasculopathy (OR, 1.07), enterocolitis (OR, 1.07), peripheral neuropathy (OR, 1.07), multiple nerve palsy (OR, 1.14), multiple sclerosis (OR, 1.24), skin diseases (OR, 1.05), psychotic diseases (OR, 1.07) and lipidemia (OR, 1.05) were significantly elevated for the high exposure group in the division/brigade-level proximity-based exposure analysis, compared to the low exposure group. The ORs for cerebral infarction (OR, 1.08), chronic bronchitis (OR, 1.05), multiple nerve palsy (OR, 1.07), multiple sclerosis (OR, 1.16), skin diseases (OR, 1.05), and lipidemia (OR, 1.05) were significantly elevated for the high exposure group in the battalion/company-level analysis. Conclusions: Korean Vietnam veterans with high exposure to Agent Orange experienced a higher prevalence of several self-reported chronic diseases compared to those with low exposure by proximity-based exposure assessment. The strong positive associations between perceived self-reported exposure and all self-reported diseases should be evaluated with discretion because the likelihood of reporting diseases was directly related to the perceived intensity of Agent Orange exposure.

• 한국의료질향상학회지
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• 제2권1호
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• pp.86-109
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• 1995

Clinical trials of drugs on humans is the final and most important stage in evaluating the safety and efficacy of the drugs. Good Clinical Practice(GCP) standards were announced in 1987 to protect testees' rights as well as to ensure validity of the clinical trial results, but its implementation has been delayed until now. The purpose of this study is to evaluate the preparedness of the designated institutions to abide by GCP standards during clinical trials, and thereby to determine GCP implementability at the institutions. Survey on the status of clinical trials was conducted for the designated 83 clinical trial hospitals. Response rate was 95.2%. Donabedian's quality assessment model was applied as the basic framework for the study. And the relative - weights for the evaluation items were determined by expert's evaluation. Among the designated 83 hospitals, 39 conducted clinical trials to obtain drug manufacturing approval from 1990 to 1994. Only 19 institutions are found to be able to meet the requirements of KGCP. Structure variables - manpower, organization, and facility -, which are the basic elements for GCP, are evaluated as unsatisfied in many hospitals. Institutions which established IRB accounted for 41 or 51.9%, but those who have a protocol evaluation guideline, or Adverse Drug Reaction(ADR) reporting system were only 12 and 21 institutions, respectively. Also, the institutions providing educational programs on conducting clinical trials are few - 20. The study results indicates that the level of conducting KGCP is unsatisfactory. However, more institutions are expected to be able to meet the standards soon because GCP standards does not require so much regulation on facilities, but stress importance on research methodology and human right. At present as the institutions for clinical trials are primarily training hospitals with residency programs, such efforts as education will accelerate the implementability of GCP in Korea. Institutions must build the appropriate infrastructure and government must prepare to strongly enforce KGCP before it can successfully take place.

• 여성건강간호학회지
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• 제5권3호
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• pp.327-336
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• 1999

The purpose of this study was to identify the health promotion behavior and its related factors of persons who wanted a comprehensive health check-up in order to provide a basis for health education to promote health enhancing behavior. Study variables were induced from Pender's Health Promotion Model. The subjects were 160 persons who had a check-up at the health promotion center in a university hospital in Tae-Gu, between September 8 and 22, 1998. The following instruments were used in the study : Lee Tae Wha's Health Promoting Life-style Profile, Park Chai soon's Self-efficacy Instrument and Moon Jeong Soon's Perceived Benefit and Barrier Instrument. Data was collected by self-reporting questionnaire. Analysis of the data was done by SAS program, t-test, ANOVA and Pearson-Correlation Coefficient. The results of this study were as follows. 1. The average score for the health-promotion behavior was 104.64. In the subcategories, self-actualization showed the highest degree of performance and physical exercise showed the lowest degree of performance. 2. In the relation of general characteristics of subjects to the level of health-promoting behavior, the male, the married, the group with several symptoms showed a high level of health-promoting behavior. 3. The relationship between the degree of performance in health-promotion behavior and its correlates were as follows: Self-efficacy was positively correlated to health promotion behavior, while the perceived barrier was correlated negatively. But the perceived benefit did not show a significant correlation with health promotion behavior. Results suggest that the development of programs with strategies to strengthen doing physical exercise and concerning health, increase self-efficacy and exclude the barriers to health promotion is recommended to individuals seeking a comprehensive health check-up.

• 한국콘텐츠학회논문지
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• 제9권10호
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• pp.339-348
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• 2009

본 연구는 지속가능성보고서평가 시 지속가능한 기업을 어떻게 구분할 것인가에 대한 문제를 제기하고, 이에 대한 해결방안을 기업 지속가능가치에서 찾아보며, 이를 지속가능성보고서를 토대로 기업의 지속가능성 평가에 활용할 수 있는 방안을 모색하는 것을 목적으로 한다. 지속가능가치는 기업이 지속가능경영을 위한 현재와 미래에 필요한 자원을 적절히 관리하고 있는가를 파악하기 위해 경제, 사회 그리고 생태적 영역에 걸친 성과를 평가하는 방법론이다. 기존의 지속가능성평가모델들이 기업이 생산활동을 통해 얼마나 많은 외부효과를 발생시켰는지를 평가하는 부하 지향적 방법이었다면 지속가능가치는 한정된 자원을 얼마나 효율적으로 사용하여 비교대상보다 더 많은 가치를 창출하였는가의 관점에서 지속가능경영 성과를 평가하는 가치 지향적 방법이라 할 수 있다. 본 연구의 결과로 제시된 지속가능보고서를 토대로 한 지속가능가치 평가는 지속가능성보고서의 질, 지속가능성보고서 내용의 충실성뿐만 아니라, 지속가능성보고서가 기술하고 있는 기업의 지속가능경영성과를 종합적으로 평가할 수 유용한 수단이 될 수 있을 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권3호
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• pp.2141-2146
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• 2013

Cervical cancer is the third most common form of cancer that strikes Malaysian women. The National Cancer Registry in 2006 and 2007 reported that the age standardized incidence (ASR) of cervical cancer was 12.2 and 7.8 per 100,000 women, respectively. The cumulative risk of developing cervical cancer for a Malaysian woman is 0.9 for 74 years. Among all ethnic groups, the Chinese experienced the highest incidence rate in 2006, followed by Indians and Malays. The percentage cervical cancer detected at stage I and II was 55% (stage I: 21.0%, stage II: 34.0%, stage III: 26.0% and stage IV: 19.0%). Data from Ministry of Health Malaysia (2006) showed a 58.9% estimated coverage of pap smear screening conducted among those aged 30-49 years. Only a small percentage of women aged 50-59 and 50-65 years old were screened, 14% and 13.8% coverage, respectively. Incidence of cervical cancer was highest (71.6%) among those in the 60-65 age group (MOH, 2003). Currently, there is no organized population-based screening program available for the whole of Malaysia. A pilot project was initiated in 2006, to move from opportunistic cervical screening of women who attend antenatal and postnatal visits to a population based approach to be able to monitor the women through the screening pathway and encourage women at highest risk to be screened. The project was modelled on the screening program in Australia with some modifications to suit the Malaysian setting. Substantial challenges have been identified, particularly in relation to information systems for call and recall of women, as well as laboratory reporting and quality assurance. A cost-effective locally-specific approach to organized screening, that will provide the infrastructure for increasing participation in the cervical cancer screening program, is urgently required.

• 보건교육건강증진학회지
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• 제26권1호
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• pp.129-140
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• 2009

Objectives: This study aimed to examined the socioeconomic disparities in oral health related behaviors and to assess if those behaviors eliminate socioeconomic disparities in oral health in a nationally representative sample of adults aged 30-64. Methods: Data are from the Korea Third National Health and Nutrition Examination Survey (2005). Behaviors were indicated by smoking, over intake of daily calories from carbohydrate, perceived stress, frequency of daily tooth brushing, use of oral hygiene goods, insufficient oral treatment. Oral health outcomes were self-reported dental caries and periodontitis during the last 12 months and perceived oral health. Education, household income, and employed status indicated socioeconomic position. Sex, age, residential area, marital status were adjusted for in the logistic regression analysis. Logistic regression analysis was used to assess socioeconomic disparities in behaviors. Logistic regression model adjusting and not adjusting for behaviors were compared to assess the change in socioeconomic disparities in oral health. Results: Clear socioeconomic disparities in all behaviors were showed. After adjusting for behaviors, the association between oral health and socioeconomic indicators attenuated but did not disappear. For example, the odd ratios of reporting poorer oral health for persons in no education or elementary school education and middle school education groups, compared with college or higher education group, were 1.77 (95% CI: 1.36-2.29) and 1.56 (1.19-1.97), respectively. After adjusting for all indicators of behaviors, these odds ratios attenuated to 1.54 (1.17-2.03) and 1.48 (1.15-1.91) for those groups, respectively. Conclusion: These findings suggest that the presence of more complex determinants of socioeconomic disparities in oral health should be considered with developing preventive policies for those disparities.

• 한국안전학회지
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• 제33권1호
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• pp.148-161
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• 2018

A traffic fatality by young people marked average annual decrease of 4.5% since 2011. Meanwhile, a traffic fatality by senior over 65 years old marked average annual increase of 7.9% for the last five years which means that the annual increase of traffic fatality by senior will be a serious problem. This study started questioning that senior drivers over 65 years old did not retain the same causal factor of fatal traffic accidents and thus extensively analyzed a risk of it by age group quantitatively, dividing the senior driver group into the early, middle and latter stages. Depending on the aging level, the risk of traffic fatality showed a wide difference in seven different types of traffic accidents generally, and happened to increase with latter and middle parts of the senior driver more than the early part. Therefore, this study proposes four policy suggestions: 1) The senior driver need to be offered customized driving educations and the improvement of road environment is also recommended. 2) Political assistance is needed to support and guide a safety related technology installation for the new or existing car. 3) Renewal of driving license and an aptitude test(physical examination, cognitive test) for drivers over 75 years old should take in a less than 3 years and an additional road test is needed as occasion demands. 4) Like the United States and Europe, development and extension of customized treatment guidebook for medical teams who examine senior drivers is needed and establishment of education and administration system that a supervisor of driving license renewal can impose safety restriction and American anonymity reporting system is considered to institutionalize in the medium to longer term.

• Asian-Australasian Journal of Animal Sciences
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• 제31권11호
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• pp.1781-1794
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• 2018

Objective: This meta-analysis was conducted to evaluate the overall effect of direct-fed microbial (DFM) or probiotic supplementation on the log concentrations of culturable gut microbiota in broiler chickens. Methods: Relevant studies were collected from PubMed, SCOPUS, Poultry Science Journal, and Google Scholar. The studies included controlled trials using DFM supplementation in broiler chickens and reporting log concentrations of the culturable gut microbiota. The overall effect of DFM supplementation was determined using standardized mean difference (SMD) with a random-effects model. Subgroups were analyzed to identify pre-specified characteristics possibly associated with the heterogeneity of the results. Risk of bias and publication bias were assessed. Results: Eighteen taxa of the culturable gut microbiota were identified from 42 studies. The overall effect of DFM supplementation on the log concentrations of all 18 taxa did not differ significantly from the controls (SMD = -0.06, 95% confidence interval [-0.16, 0.04], p = 0.228, $I^2=85%$, n = 699 comparisons), but the 18 taxa could be further classified into three categories by the direction of the effect size: taxa whose log concentrations did not differ significantly from the controls (category 1), taxa whose log concentrations increased significantly with DFM supplementation (category 2), and taxa whose log concentrations decreased significantly with DFM supplementation (category 3). Category 1 comprised nine taxa, including total bacterial counts. Category 2 comprised four taxa: Bacillus, Bifidobacterium, Clostridium butyricum, and Lactobacillus. Category 3 comprised five taxa: Clostridium perfringens, coliforms, Escherichia coli, Enterococcus, and Salmonella. Some characteristics identified by the subgroup analysis were associated with result heterogeneity. Most studies, however, were present with unclear risk of bias. Publication bias was also identified. Conclusion: DFM supplementation increased the concentrations of some beneficial bacteria (e.g. Bifidobacterium and Lactobacillus) and decreased those of some detrimental bacteria (e.g. Clostridium perfringens and Salmonella) in the guts of broiler chickens.

• 복식
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• 제22권
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• pp.23-44
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• 1994

The purpose of this study was to clarify the cultural characteristic of dress and adornments by examining articles on dress adornments and related items in Korean newspaper over periods historically and objectively by means of content analysis. This study attempted to at-tain a macro-cultural view by analysing to at-tain a macro-cultural view by analysing closely the cultural characteristics of dress and adornments as a micro-cultural system through culturally based model suggested by hamilton. The two-hundreds and eighty articles on dress and adornments were selected from newspapers(most by form Chosun Ilbo and partly from Maeil Shinbo) pulished between 1920 and 1990. The results were as follows: 1. The culture of dress and adornment received much attention during the 1930's and 1960's and little during 1950's. 2. Various cultural characteristics of dress and adornments appeared on and after 1960's: reporting more foreign news items showing foreign-oriented and future-oriented features showing cultural relativism. In the 1920's and 1970's the contents of news items on dress and adornments show the most common- mass- oriented character. Foreign-oriented cultural tendencies in cloth-ing were increasing during from 1960's to 1970's but the tendencies were turned to rather tradition-oriented features on and after 1980's compare with 1960's-1970's. Advisory critical articles on dress and adornments were small in number and insignificant but compare with other periods these received much atten-tion during the 1920's and 1980's. 3. Ideological components received much at-tention on and after 1920's to 1990. Techo-nological components received much attention during 1920's and little during 1960's. The social structural components received a little attention on and after 1920's-1940's and 1990. 4. News items on women's dress and adornments received much attention from the 1920's to 1960's and news items on both men's and women's dress and adorments were in-creasing and received much attention on and after the 1970's. 5. The pragmatic cultures were mostly re-lated to techonological components and evaluative-normative culture were mostly re-lated to ideological and social structural components. In the light of these results dress and adorments as a cultural sub-system comprise a dynamic inteacting system that articulated directly with the macro-cultural system.

• The Journal of Asian Finance, Economics and Business
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• 제4권3호
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• pp.5-17
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• 2017

This study extends research into whether disclosure of corporate and financial information is associated with firms' costs of equity capital. This study sets out to examine empirically the determinants of corporate disclosure in the annual reports of 37 largest and most liquid firms listed on Kazakhstan Stock Exchange (KASE) in Kazakhstan. It also reports the results of the association between company-specific characteristics and disclosure of the sample companies. Based on the analysis of existing empirical research, the disclosure index has been constructed and regression analysis of the influence of the disclosure index on the cost of equity capital has been conducted. The obtained results show that the received findings correlate with foreign empirical studies, and the disclosure index in this sample has a negative impact on the cost of equity capital. Using cost of equity capital estimates derived from capital asset pricing model, we find that firms with higher levels of financial transparency are associated with significantly lower costs of equity capital. Economic theory assumes that by increasing the level of corporate reporting, firms not only increase their stock market liquidity, but also decrease the investors' estimation risk, arising from uncertainty about future returns and payout distributions. The results show that firms on the Kazakhstan market can reduce their cost of equity capital by increasing the level of their voluntary corporate disclosures.