• 대한영상의학회지
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• 제83권5호
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• pp.1059-1070
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• 2022

목적 계산형 확산강조영상 b2000과 실제 획득한 확산강조영상 b2000 사이에 전립선암 발견을 위한 민감도 및 관찰자 간 일치도를 비교하였다. 대상과 방법 근치적 전립선 절제술 및 확산강조영상(b, 0, 100, 1000, 2000 s/mm²)을 포함한 수술 전 3 Tesla 자기공명영상을 통해 전립선암으로 진단받은 총 88명의 환자가 연구에 포함되었다. 계산형 확산강조영상 b2000은 실제 획득한 확산강조영상 b0, 100, 1000으로부터 단일 지수 감쇠 모델에 의해 계산되었다. 두 명의 독립된 검토자가 4주 간격으로 무작위 순서로 두 영상 세트를 검토하여, 가장 큰 종양에 대해 관심 영역을 그렸고, Prostate Imaging-Reporting and Data System 2.1에 기반한 점수를 기록하였다. 전층 절편 조직 검사가 참고 기준으로 제공되었다. 결과 연구에 포함된 환자의 글리슨 점수는 6 (n = 16), 7 (n = 53), 8 (n = 9), 9 (n = 10)로 구성되었다. 두 명의 검토자 모두 계산형 확산강조영상 b2000과 실제 획득한 확산강조영상 b2000 간 전립선암 발견에 대한 민감도 차이는 없었다(검토자 1, 모두 94% [83/88]; 검토자 2, 모두 90% [79/88], 모두 p = 1.000). 관찰자 간 PI-RADS 점수에 대한 일치도는 계산형 확산강조영상에서 0.422 (95% 신뢰구간, 0.240-0.603), 실제 획득한 확산강조영상에서 0.495 (95% 신뢰구간, 0.308-0.683)였다. 결론 계산형 확산강조영상 b2000과 실제 획득한 확산강조영상 b2000은 전립선암 발견 민감도에 차이가 없고, 관찰자 간 일치도는 유지되었다.

• 유통과학연구
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• 제10권12호
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• pp.35-43
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• 2012

Purpose - This study analyzes the effects of types of leadership on the employees of Italian restaurants, its efficacy, and organizational citizenship behavior, utilizing a causal assessment model. In this study, independent variables such as the type of leadership perceived in the manager or chef by an Italian restaurant's employees, and its efficacy were parameters, and the organizational citizenship behavior and organizational effectiveness were the variables representing the results in the hypothesis. The study aimed to draw implications by verifying the leadership via efficacy and the impact on organizational citizenship behavior of Italian restaurants. Research design, data, methodology - For the purpose of this analysis, specific questionnaire items were configured according to the theory and efficacy of the study. From a questionnaire used in organizational citizenship behavior comprising 22 questions, six were modified to suit the research purpose of this study. The configured questionnaire comprised 5 parts and 40 items. A Likert (Likert) 5-point scale was utilized to measure responses to the questionnaire items from the employees of an Italian restaurant in Seoul who participated in the survey. For data collection, 400 questionnaires were distributed, and 344 collected. Factor analysis and reliability verification were conducted using SPSS18.0 and AMOS18.0. A covariance structure analysis was conducted to test the research hypotheses. Results - Based on the results of the analyses, the summary and suggested implications of the research are as follows: The covariance structure analysis used to analyze the kind of effect transformational and transactional leadership styles in Italian restaurant employees had on self-efficacy, group-efficacy, and organizational citizenship behavior, indicated that among the characteristics of transformational leadership (such as, idealized influence, inspirational motivation, individual consideration, and intellectual stimulation), idealized influence and individual consideration had a positive influence on self-efficacy. Idealized influence, individual consideration, conditional reward, and management by exception also positively influenced self-efficacy and altruistic and conscientious behavior (organizational citizenship behavior). Conclusions - Results suggest that with regard to self-efficacy and group efficacy, managers in different departments and chefs should provide team members with a vision for the future, increase their confidence in their abilities, and build their trust in the organization. By evaluating employee performance and experiences, management can demonstrate leadership and encourage organizational citizenship behavior through enjoyable, voluntary participation. Transformational and transactional leadership is effective in group processes that include social-exchange relationships, self-efficacy and group efficacy, and organizational citizenship behavior. However, as this research study utilizes only self-reported data, it has several limitations, such as a vulnerability of errors caused by the various experiment types. A significant limitation of this study is the lack of potential for the duplication of results. The covariance structure analysis, however, provides complementation to limit the impact of errors from self-reporting studies. A future study can extend this research by utilizing different data collection methods.

• 시큐리티연구
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• 제59호
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• pp.161-188
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• 2019

범죄신고는 형사사법의 실효성을 높이는데 있어서 중요한 내용이기에 일반국민들을 대상으로 한 연구가 꾸준히 진행되고 있다. 그러나 우리사회 소외계층에 해당하는 북한이탈 주민들의 범죄신고에 대한 연구는 찾아보기 어렵다. 본 연구는 국내에 입국한 수도권 거주 800명의 북한이탈주민을 대상으로 한 설문조사를 기반으로 범죄피해의 신고의지에 영향을 미치는 요인을 실증적으로 살펴보았다. 법적 냉소주의 모델과 절차적 정당성 모델을 바탕으로 북한이탈주민들이 형사사법기관의 활동에 대해 느끼는 법적 냉소주의와 공정성 인식 수준이 북한이탈주민의 형사사법기관에 대한 범죄피해의 신고의지에 긍정적인 영향을 미친다는 가설을 검증하여 기대했던 결과를 확인할 수 있었다. 반면에, 도널드 블랙이 법행동 이론에서 제시한 종적분화, 횡적분화, 문화, 조직, 사회통제 등 다섯 가지 유형별로 도출한 사회조건을 기반으로 한 가설 대부분은 범죄피해의 신고의지에 유의미한 연관성이 발견되지 않거나, 상충된 결과를 보였다. 이 연구는 선행연구에서 소외되었던 북한이탈주민에 주목하여 범죄신고 의지에 영향을 미치는 요인을 살펴보았다는데 의의가 있으며 분석결과를 토대로 북한이탈주민들의 형사사법기관에 대한 신뢰도를 높이고 법적 냉소성을 감소함으로써 범죄신고 의지를 고양하는 방안에 대하여 논하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권10호
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• pp.4339-4345
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• 2015

Occupational exposure to wood dust is one cause of nasopharyngeal cancer (NPC); however, assessing this exposure remains problematic. Therefore, the objective of this study was to develop a semi-quantitative exposure assessment method and then utilize it to evaluate the association between occupational exposure to wood dust and the development of NPC. In addition, variations in risk by histology were examined. A case-control study was conducted with 327 newly diagnosed cases of NPC at the National Cancer Institute and regional cancer centers in Thailand with 1:1 controls matched for age, gender and geographical residence. Occupational information was obtained through personal interviews. The potential probability, frequency and intensity of exposure to wood dust were assessed on a job-by-job basis by experienced experts. Analysis was performed by conditional logistic regression and presented in odds ratio (ORs) estimates and 95% confidence intervals (CI). Overall, a non significant relationship between occupational wood dust exposure and NPC risk for all subjects was observed (ORs=1.61, 95%CI 0.99-2.59); however, the risk became significant when analyses focused on types 2 and 3 of NPC (ORs=1.62, 95%CI 1.03-2.74). The significant association was stronger for those exposed to wood dust for > 10 year (ORs=2.26, 95%CI 1.10-4.63), for those with first-time exposure at age > 25 year (ORs=2.07, 95%CI 1.08-3.94), and for those who had a high cumulative exposure (ORs=2.17, 95%CI 1.03-4.58) when compared with those considered unexposed. In conclusion, wood dust is likely to be associated with an increased risk of type 2 or 3 NPC in the Thai population. The results of this study show that semi-quantitative exposure assessment is suitable for occupational exposure assessment in a case control study and complements the information from self-reporting.

• 한국ITS학회 논문지
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• 제19권5호
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• pp.70-81
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• 2020

GPS가 탑재된 차내 단말기, 스마트폰에서 방대하게 수집되는 초 단위 위치(위·경도) 데이터는 교통 분야에 다양하게 활용되고 있다. 이러한 데이터는 공공의 교통관련 의사결정자들과 교통서비스를 개발·제공하는 민간회사들에게 운전자들의 행태와 교통흐름을 미시적으로 파악할 수 있게 한다. 특히, 속도 데이터는 통행시간 예측에 주요한 정보로 활용되며, 해상도 높은 데이터 기반의 고차원 서비스 개발에 이용되고 있어 신뢰성있는 정보의 확보가 요구된다. 그럼에도 불구하고 링크별 속도 산출 시 각기 다른 저장, 수집주기 등을 기준으로 사용하고 있어 정보 활용에 있어 신뢰성을 담보하기 어렵다. 본 연구의 목적은 차내 단말기를 장착한 프로브차량 데이터를 수집해 링크 공간평균속도를 산출하고 동일 구간 및 시간대의 영상기반 공간평균속도와 비교분석을 통해 오차율을 도출하는 것이다. 수집주기와 실제 속도 상황에 따른 오차율을 분석한 결과 8초 이내 수집주기에서 95% 신뢰수준을 보였으며 이를 공간평균속도 산출 시 신뢰성확보를 위한 적정 수집 주기로 제안했다. 해당 결과는 향후 커넥티드 환경에서 수집될 핵심 정보들의 신뢰성 확보와 서비스 개발 시 기초 정보로 활용될 것으로 기대해본다.

• 대한한방내과학회지
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• 제43권4호
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• pp.542-558
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• 2022

Objectives: The purpose of this study was to assess the effect of Yigong-san on anorexia in children by conducting a systematic review and meta-analysis of randomized controlled trials (RCTs). Methods: Eleven electronic databases were searched on May 30, 2022 to collect relevant studies. All studies published up to the search date were considered. RCTs reporting the effect of Yigong-san on the treatment of anorexia in children were included. The primary outcome was an improvement in clinical anorexia symptoms after treatment. In this meta-analysis, continuous and binary outcomes were assessed, and the data were presented as the mean difference and risk ratio with their 95% confidence intervals. The risk of bias was assessed using the Cochrane Collaboration's risk of bias tool. Results: A total of nine studies were included in this systematic review. The treatment group (Yigong-san only or Yigong-san plus conventional treatment) showed a statistically significant effect compared to the control group (conventional treatment only) in total effective rate (Yigong-san only: RR 1.26, 95% CI 1.17, 1.36, I²=0%; Yigong-san plus conventional treatment: RR 1.32, 95% CI 1.18, 1.47, I²=0%), clinical symptoms, some of the anthropometric outcomes, and biological markers related to appetite and growth in children with anorexia. No serious adverse events related to Yigong-san were reported. Conclusions: Yigong-san showed statistically significant effects as a treatment for anorexia in children. However, the number of studies included in the meta-analysis was insufficient, and the herbs contained in the Yigong-san used in the included studies were not standardized. Future research should focus on the implementation of methodologically robust clinical research.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제25권5호
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• pp.353-375
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• 2022

No systematic review to date has examined histopathological parameters in relation to native liver survival in children who undergo the Kasai operation for biliary atresia (BA). A systematic review and meta-analysis is presented, comparing the frequency of native liver survival in peri-operative severe vs. non-severe liver fibrosis cases, in addition to other reported histopathology parameters. Records were sourced from MEDLINE, Embase, and CENTRAL databases. Studies followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and compared native liver survival frequencies in pediatric patients with evidence of severe vs. non-severe liver fibrosis, bile duct proliferation, cholestasis, lobular inflammation, portal inflammation, and giant cell transformation on peri-operative biopsies. The primary outcome was the frequency of native liver survival. A random effects meta-analysis was used. Twenty-eight observational studies were included, 1,171 pediatric patients with BA of whom 631 survived with their native liver. Lower odds of native liver survival in the severe liver fibrosis vs. non-severe liver fibrosis groups were reported (odds ratio [OR], 0.16; 95% confidence interval [CI], 0.08-0.33; I²=46%). No difference in the odds of native liver survival in the severe bile duct destruction vs. non-severe bile duct destruction groups were reported (OR, 0.17; 95% CI, 0.00-63.63; I²=96%). Lower odds of native liver survival were documented in the severe cholestasis vs. non-severe cholestasis (OR, 0.10; 95% CI, 0.01-0.73; I²=80%) and severe lobular inflammation vs. non-severe lobular inflammation groups (OR, 0.02; 95% CI, 0.00-0.62; I²=69%). There was no difference in the odds of native liver survival in the severe portal inflammation vs. non-severe portal inflammation groups (OR, 0.03; 95% CI, 0.00-3.22; I²=86%) or between the severe giant cell transformation vs. non-severe giant cell transformation groups (OR, 0.15; 95% CI, 0.00-175.21; I²=94%). The meta-analysis loosely suggests that the presence of severe liver fibrosis, cholestasis, and lobular inflammation are associated with lower odds of native liver survival in pediatric patients after Kasai.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제49권3호
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• pp.142-147
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• 2023

Objectives: As medical history before surgery is often based on patient reporting, there is the possibility that patients intentionally hide underlying diseases or that dentists cannot recognize abnormal health states. Therefore, more professional and reliable treatment processes are needed under the Korean dental specialist system. The purpose of this study was to elucidate the necessity of a preoperative blood testing routine prior to office-based surgery under local anesthesia. Patients and Methods: Preoperative blood lab data for 5,022 patients from January 2018 to December 2019 were assembled. Study participants were those who underwent extraction or implant surgery under local anesthesia at Seoul National University Dental Hospital. Preoperative blood tests included complete blood count (CBC), blood chemistry, serum electrolyte, serology, and blood coagulation data. Values outside of the normal range were considered an "abnormality," and the percentage of abnormalities among the total number of patients was calculated. Patients were divided into two groups based on the presence of underlying disease. The rates of abnormalities in the blood tests were compared between groups. Chi-square tests were performed to compare data from the two groups, and P<0.05 was considered statistically significant. Results: The percentages of males and females in the study were 48.0% and 52.0%, respectively. Of all patients, 17.0% (Group B) reported known systemic disease, while 83.0% (Group A) reported no specific medical history. There were significant differences between Groups A and B in CBC, coagulation panel, electrolytes, and chemistry panel (P<0.05). In Group A, the results of blood tests that required a change in procedure were identified even though the proportion was very small. Conclusion: Preoperative blood tests for office-based surgery can detect underlying medical conditions that are difficult to identify from patient history alone and can prevent unexpected sequelae. In addition, such tests can result in a more professional treatment process and build patient confidence in the dentist.

• Korean Journal of Radiology
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• 제22권6호
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• pp.867-879
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• 2021

Objective: To compare the screening performance of diffusion-weighted (DW) MRI and combined mammography and ultrasound (US) in detecting clinically occult contralateral breast cancer in women with newly diagnosed breast cancer. Materials and Methods: Between January 2017 and July 2018, 1148 women (mean age ± standard deviation, 53.2 ± 10.8 years) with unilateral breast cancer and no clinical abnormalities in the contralateral breast underwent 3T MRI, digital mammography, and radiologist-performed whole-breast US. In this retrospective study, three radiologists independently and blindly reviewed all DW MR images (b = 1000 s/mm² and apparent diffusion coefficient map) of the contralateral breast and assigned a Breast Imaging Reporting and Data System category. For combined mammography and US evaluation, prospectively assessed results were used. Using histopathology or 1-year follow-up as the reference standard, cancer detection rate and the patient percentage with cancers detected among all women recommended for tissue diagnosis (positive predictive value; PPV2) were compared. Results: Of the 30 cases of clinically occult contralateral cancers (13 invasive and 17 ductal carcinoma in situ [DCIS]), DW MRI detected 23 (76.7%) cases (11 invasive and 12 DCIS), whereas combined mammography and US detected 12 (40.0%, five invasive and seven DCIS) cases. All cancers detected by combined mammography and US, except two DCIS cases, were detected by DW MRI. The cancer detection rate of DW MRI (2.0%; 95% confidence interval [CI]: 1.3%, 3.0%) was higher than that of combined mammography and US (1.0%; 95% CI: 0.5%, 1.8%; p = 0.009). DW MRI showed higher PPV2 (42.1%; 95% CI: 26.3%, 59.2%) than combined mammography and US (18.5%; 95% CI: 9.9%, 30.0%; p = 0.001). Conclusion: In women with newly diagnosed breast cancer, DW MRI detected significantly more contralateral breast cancers with fewer biopsy recommendations than combined mammography and US.

• Korean Journal of Radiology
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• 제22권8호
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• pp.1240-1252
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• 2021

Objective: To compare the accuracy for detecting breast cancer in the diagnostic setting between the use of digital breast tomosynthesis (DBT), defined as DBT alone or combined DBT and digital mammography (DM), and the use of DM alone through a systematic review and meta-analysis. Materials and Methods: Ovid-MEDLINE, Ovid-Embase, Cochrane Library and five Korean local databases were searched for articles published until March 25, 2020. We selected studies that reported diagnostic accuracy in women who were recalled after screening or symptomatic. Study quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. A bivariate random effects model was used to estimate pooled sensitivity and specificity. We compared the diagnostic accuracy between DBT and DM alone using meta-regression and subgroup analyses by modality of intervention, country, existence of calcifications, breast density, Breast Imaging Reporting and Data System category threshold, study design, protocol for participant sampling, sample size, reason for diagnostic examination, and number of readers who interpreted the studies. Results: Twenty studies (n = 44513) that compared DBT and DM alone were included. The pooled sensitivity and specificity were 0.90 (95% confidence interval [CI] 0.86-0.93) and 0.90 (95% CI 0.84-0.94), respectively, for DBT, which were higher than 0.76 (95% CI 0.68-0.83) and 0.83 (95% CI 0.73-0.89), respectively, for DM alone (p < 0.001). The area under the summary receiver operating characteristics curve was 0.95 (95% CI 0.93-0.97) for DBT and 0.86 (95% CI 0.82-0.88) for DM alone. The higher sensitivity and specificity of DBT than DM alone were consistently noted in most subgroup and meta-regression analyses. Conclusion: Use of DBT was more accurate than DM alone for the diagnosis of breast cancer. Women with clinical symptoms or abnormal screening findings could be more effectively evaluated for breast cancer using DBT, which has a superior diagnostic performance compared to DM alone.