• Computers and Concrete
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• 제30권1호
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• pp.19-32
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• 2022

This paper presents an investigation into the failure of RC columns under impact loadings. A numerical simulation of 19 identical RC columns subjected to single and repeated impact loadings was performed. A free-falling hammer was dropped at midspan with the same total kinetic energy input but varying mass and momentum. The specimens under the repeated impact test were struck two times at the same location. The colliding index, defined as the impact energy-momentum ratio, was proposed to explain the different impact responses under equal-energy impacts. The increase of colliding index from low to high indicates the transition of the impact response from static to dynamic and failure mode from flexure to shear. This phenomenon was more evident when the column had a greater axial load and was impacted with a high colliding index. The existence of the axial load had an inhibitory effect on the crack development and increased the shear resistance. The second impact changes the failure mode from flexural to brittle shear as found in the specimen with 20% axial load subjected to high a colliding index. Moreover, a deflection prediction equation based on the impact energy and force was limited to the low colliding index impact.

• Human Ecology Research
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• 제60권1호
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• pp.69-86
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• 2022

The present study examined the effectiveness of repeated marriage checkups at intervals of six months in a Family Center in Seoul. To achieve this, the pilot study protocol (Park, 2019) was adapted, emphasizing strength-based, counseling-oriented approaches. Two couples and family therapists with master's degrees were trained and their practice was monitored to ensure program fidelity. The methods employed for the assessment of marriage checkup were an online survey, a video recording of couple problem-solving, and a clinical interview. A total of 14 couples participated in the 1st checkup, 10 of whom also completed the 2nd checkup. Couples with varying levels of marital satisfaction participated in the program. Descriptive statistics indicated gradual increases over 8-9 months in diverse indices such as marital satisfaction and relationship strength, while other indices fluctuated slightly but converged to higher levels over time. A non-parametric analysis appropriate for small samples demonstrated statistically significant increases over the 8-9 months in marital satisfaction among couples. The current study evidenced the effectiveness of repeated marriage checkups in the Family Center, which is the primary public institution for family policy and services in Korea. Repeated marriage checkups are therefore a promising way to enhance couples' relationship health and improve the family management system of the Family Center.

• Structural Engineering and Mechanics
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• 제85권6호
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• pp.755-764
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• 2023

The article examines the impact response of the sandwich beam furnished by a novel bilayer core as inspired by the woodpecker's head architecture under different repeatedly exerted low-velocity impact loadings by employing the finite element package, ABAQUS. The sandwich beam forms four essential parts comprising bottom and top carbon fiber reinforced polymer laminates encasing bilayer core made of laterally arched solid hot melt adhesive material and aluminum honeycomb. Impact loadings are implemented repeatedly with a steel hemisphere impactor for various impact energies, 7.28 J, 9.74 J, and 12.63 J. Essentially, the commonly concentrated stresses at the impact region are regulated away by the arched core in all considered cases thus reducing the threat of failure. The sandwich beam can resist up to 5 continual impacts at 7.28 J and 9.74 J but only up to 3 times repeated loads at 12.63 J before visible failure is noticed. In the examination of several key impact performance indicators under numerous loading cases, the proposed beam demonstrates favorably up to 1.3-11.2 higher impact resistance efficacies compared to existing designs, therefore displaying an improvement in repeated impact resistance of the new design.

• 대한토목학회논문집
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• 제28권3D호
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• pp.325-330
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• 2008

GFRP 다웰바의 장기 내구성능 저하 메커니즘을 규명하기 위하여 실제 콘크리트 포장에서 발생할 수 있는 수분환경과 동결융해반복 환경하의 촉진 내구성능 평가를 실시하였으며 그에 따른 미세구조 분석을 통해 성능저하 열화 진행 메커니즘을 분석하였다. GFRP 다웰바의 내구특성 평가는 촉진환경에 노출 후 전단시험을 실시하여 분석하였으며 미세구조 분석을 위하여 SEM 사진과 가스흡착에 의한 공극측정을 실시하였다. 실험결과 수분환경 및 동결 융해반복 환경에 노출된 GFRP 다웰바는 내구특성 저하가 거의 나타나지 않았다. 이와 같은 결과는 미세구조분석에서 명확히 관찰 할 수 있었다.

• 한국구조물진단유지관리공학회 논문집
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• 제10권1호
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• pp.183-189
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• 2006

RC 구조물에 대하여 FRP로 보수 보강 작업시, 주변 온도에 따른 일정기간의 양생을 필요로 하며 또한 양생과정 중 외부의 진동원으로부터 유해한 작용을 받는 것을 피하는 것이 바람직하다. 따라서 본 연구에서는 탄소섬유쉬트(CFS)로 보강되는 RC구조물에 대하여, CFS양생과정 중 작용하는 반복하중이 보강성능에 미치는 영향을 일련의 보 실험을 통하여 분석하였다. 실험결과 CFS 1겹 보강의 경우에는 CFS부착 후 24시간, 2겹 보강의 경우에는 12시간동안 외부로부터의 반복하중을 차단하는 것이 필요한 것으로 판단되었다.

• 대한약침학회지
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• 제17권2호
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• pp.18-26
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• 2014

Objectives: This study was performed to check for reversibility in the changes induced by a 13-week, repeated, dose toxicity test of Sweet Bee Venom (SBV) in Sprague-Dawley (SD) rats. Methods: Fifteen male and 15 female SD rats were treated with 0.28 mg/kg of SBV (high-dosage group) and the same numbers of male and female SD rats were treated with 0.2 mL/kg of normal saline (control group) for 13 weeks. We selected five male and five female SD rats from the high-dosage group and the same numbers of male and female SD rats from the control group, and we observed these rats for four weeks. We conducted body-weight measurements, ophthalmic examinations, urinalyses and hematology, biochemistry, histology tests. Results: (1) Hyperemia and movement disorder were observed in the 13-week, repeated, dose toxicity test, but these symptoms were not observed during the recovery period. (2) The rats in the high-dose group showed no significant changes in weight compared to the control group. (3) No significant differences in the ophthalmic parameters, urine analyses, complete blood cell counts (CBCs), and biochemistry were observed among the recovery groups. (4) No changes in organ weights were observed during the recovery period. (5) Histological examination of the thigh muscle indicated cell infiltration, inflammation, degeneration, necrosis of muscle fiber, and fibrosis during the treatment period, but these changes were not observed during the recovery period. The fatty liver change that was observed during the toxicity test was not observed during the recovery period. No other organ abnormalities were observed. Conclusion: The changes that occurred during the 13-week, repeated, dose toxicity test are reversible, and SBV can be safely used as a treatment modality.

• The Korean Journal of Physiology and Pharmacology
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• 제11권4호
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• pp.139-144
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• 2007

Recent studies suggest that alterations in glutamate receptor subunit levels in mesocorticolimbic dopamine areas could account for neural adaptations in response to psychostimulant drugs. Although many drugs of abuse induce changes in ionotropic glutamate receptor subunits in mesocorticolimbic dopamine areas, the changes of ionotropic glutamate receptor subunits by repeated nicotine treatment in these areas are not known. To answer this question, we injected male Sprague-Dawley rats twice daily with nicotine (0.4 mg/kg) or saline (1 ml/kg) for 10 days. The immunoreactivity of NR1, GluR1, and GluR2 glutamate receptor subunits was examined $16{\sim}18 h$ after the last injection of saline or nicotine. Repeated nicotine treatment significantly increased NR1 levels in the ventral tegmental area (VTA). In addition, repeated nicotine treatment showed a tendency towards an increase in GluR1 levels in the VTA as well as in striatum. However, there was no significant change in glutamate receptor subunits in other areas including nucleus accumbens (NAc). These results demonstrate that repeated nicotine treatment increases NR1 levels in VTA similarly to other drugs of abuse, suggesting that elevated glutamate receptor subunits in the VTA, but not NAc may be involved in the excitation of mesocorticolimbic dopamine neurons by nicotine.

• 한국초지조사료학회지
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• 제18권3호
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• pp.195-204
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• 1998

This study was designed to investigate the effects of antagonistic microorganism, Bacillus subtilis, on the growth of forage seedlings in repeated cultivation soils and unrepeated cultivation soils. The field experiment was wnducted in pots in a vinyl house using repeated and unrepeated cultivation soils. Forage types were 'Suwon 19' wrn(Zea mqs L.), 'Califbmia' white clover(Tr~oIium repens L.) and 'Fawn' tall fescue (Festuca arundianacea Schreb.). Samples of white clover and tall fescue were taken h m each pot at 36 days after seeding. Samples of wm were examined at 50 days after seeding. The most active antagonistic bacterium was isolated h m forage rhizosphere soil, and selected by reference to it's antagonistic ability on the growth of pathogenic fungi, Rhizoctonia solmi and Fusarium oxyspomm, and it was identified as Bacillus subtilis. This strain strongly suppressed the growth of fungal pathogens among isolated rhizobacteria. The dry weight of forage shoots and roots cultivated in unrepeated cultivation soils was higher than that cultivated in repeated cultivation soils. The dry weight of forage was positively affected by the inoculation of the antagonistic bacterium, Bacillus subtilis, in both repeated cultivation soils and unrepeated cultivation soils. In conclusion, the growth of forage was more affected by the inoculation of the antagonistic bacterium in unrepeated cultivation soils than that in repeated cultivation soils, and bacterization of forage with B. subtilis resulted in an inrreased yield.

• 한국지반공학회논문집
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• 제21권10호
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• pp.85-97
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• 2005

보강토 구조물은 그동안의 다양한 분야에서의 적용을 통해 기존의 옹벽구조물의 대체 공법으로서 그 적용성을 인정받고 있다. 최근 들어 교대 및 철도 시설 등에 적용됨에 따라 단기적인 안정성 이외에 장기적으로 지속하중 혹은 반복하중에 노출됨에 따른 장기거동에 대한 연구의 필요성이 높아가고 있다. 본 연구에서는 이러한 연구의 필요성에 근거하여 보강토체에 발생할 수 있는 장기변형 특성 고찰에 주안점을 두고 우리나라에서 생산되는 지오그리드와 화강풍화토로 형성된 보강토에 대한 지속하중 혹은 반복하중 등 다양한 하중이력에 대한 보강토 구조물의 장기 변형 특성 메카니즘을 평면변형압축(plane strain compression; PSC)시험을 통해 고찰하였다. 그 결과 보강토의 시간 의존적 압축변형은 보강토체에 작용하는 하중 특성뿐만 아니라 보강재의 역학적 특성에도 많은 영향을 받는 것으로 나타났으며, 선행하중을 작용함으로써 시간 의존적 잔류변형을 제어할 수 있는 것으로 분석되었다.

• 동의신경정신과학회지
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• 제24권1호
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• pp.131-144
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• 2013

Objectives : To provide information on the safety of ACM, we carried out a single oral dose-increasing toxicity and 4-weeks repeated oral dose determining test of ACM in beagle dogs. Methods : In a single oral dose-increasing toxicity test, beagles were treated with ACM orally increasing dose level (1,000, 2,000, 5,000 mg/㎏) at interval of 3 days. After administration, signs of toxicity were observed for two weeks. In 4-weeks repeated oral dose determinating test, beagles were treated with ACM with oral dose 500, 1,000, 2,000 mg/kg for 4 weeks. Mortality, clinical signs, body weight changes, food consumption, urinalysis, hematological and biochemical parameters, organ weights, necropsy findings, and histological findings were monitored during the study period. Results : In a single oral dose-increasing toxicity test, we found no mortality, abnormalities in clinical signs, body weight, and necropsy findings during the study period. In 4-weeks repeated oral dose determinating test, we found no mortality, abnormalities in clinical signs, body weight, food consumption, urinalysis, hematological and biological parameters, gross findings, organ weights, necropsy findings, and histopathological findings in any of the beagles tested. Conclusions : The results obtained in these studies suggest that maximum tolerated dose (MTD) of ACM in male and female beagle dogs was supposed to be over 5,000 mg/kg. For the future studies of toxicity, it is advisable that high dose and low dose are set at 2000 mg/kg and 500 mg/kg, respectively.