• Annals of Clinical Neurophysiology
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• v.9 no.1
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• pp.33-35
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• 2007

Meralgia paresthetica (MP) is a benign entrapment neuropathy which is characterized by sensory impairment and paresthesia in the cutaneous distribution of the lateral femoral cutaneous nerve. A 79-year-old woman presented with intermittent right inguinal burning sensation. The sensory nerve conduction study (NCS) showed decreased right side sensory nerve action potential (SNAP) on lateral femoral cutaneous nerve compared to the contralateral one. Abdomino-pelvic CT showed bilateral huge renal cysts (The size of largest one on right side: about $6.2{\times}5.0cm$). We report a case of MP caused by a huge abdominal renal cyst, which should be considered when conventional examination reveals no responsible etiology.

• Journal of Veterinary Science
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• v.24 no.5
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• pp.61.1-61.12
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• 2023

Background: Percutaneous renal cyst sclerotherapy (PRCS) as a treatment for renal cysts is usually performed with a high concentration of ethanol (≥ 90%). This study reviewed cases in which a lower concentration of ethanol (83%) was used for the procedure in dogs. Methods: Records of cases of renal cysts treated by sclerotherapy using 83% ethanol in dogs were reviewed. Outcomes of the treatment were evaluated by comparing volumes of renal cysts before the procedure and the volumes after treatment, using ultrasound images with the volume reduction rates classified as follows: < 50% of initial volume (failed); ≥ 50% but < 80% of initial volume (partial success); ≥ 80% but < 95% of initial volume (great success); ≥ 95% of initial volume (complete success). Results: Out of nine dog kidneys, renal cysts sclerotherapy with 83% ethanol achieved partial success in one kidney, great success in four, and complete success in the other four. No side effect was observed. The mean of the volume-reduction rates was 90.00 ± 11.00 while the minimum and maximum reduction rates were 65% and 100%, respectively. Conclusions: The lower ethanol concentration (83%) is good for disinfecting kidneys in PRCS.

• Childhood Kidney Diseases
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• v.18 no.2
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• pp.132-136
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• 2014

Tuberous sclerosis complex (TSC) is a genetic disorder that affects multiple organ systems and causes tumors. It is important that physicians are aware of the manifestations of TSC, and that they follow the recommendations for screening and evaluation. Several types of renal abnormalities may develop in individuals with TSC. Individuals with TSC may require ongoing treatment that can be adapted for each arising manifestation of renal disease. Herein, we report 4 patients with TSC who presented with a range of different renal manifestations, including angiomyolipoma, renal cell carcinoma, renal infarction, renal cyst, and nephrolithiasis.

• Journal of Veterinary Clinics
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• v.25 no.3
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• pp.224-226
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• 2008

A 13-year-old, spayed female, Yorkshire terrier was presented with a history of vomiting and diarrhea. Radiographic and ultrasonographic studies suggested rupture of right renal cyst. Left kidney had increased cortical echogenecity with indistinct corticomedullary junction on sonogram. Unilateral nephroureterectomy of right kidney was performed. Histopathologic examination of the resected renal mass confirmed a renal cystadenocarcinoma. To the best of our knowledge, it is the first case report of renal cystadenocarcinoma in a small breed dog in Korea.

• Korean Journal of Veterinary Research
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• v.29 no.4
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• pp.559-565
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• 1989

In order to investigate the renal pathology of spontaneously occurring renal lesions, basic macroscopic inspection was conducted to 3,850 pigs randomly collected from local slaughter houses, and a total of 355 pigs (9.2%) were detected with various gross pathological conditions. Renal morphologic patterns for gross lesions were classified histopathologically as 123(34.5%) congestion, 81(22.8%) acute interstitial nephritis, 52(14.7%) chronic interstitial nephritis, 49(13.8%) hemorrhage, 39(11.0%) renal cyst, 29(8.2%) chronic glomerulonephritis, 18(5.1%) acute glomeruonephritis, 14(3.9%) infarction, 11(3.1%) thrombosis, 5(1.4%) atrophy, 5(1.4%) pyelonephritis and 1(0.3%) lymphosarcoma.

• Journal of Veterinary Clinics
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• v.38 no.6
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• pp.295-298
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• 2021

A 1-year-old spayed female Scottish Fold cat presented with a 1.5-month history of vomiting, intermittent dyspnea, and abdominal distention. Radiographic, ultrasonographic, and computed tomographic examinations suggested a tentative diagnosis of a fluid-containing cystic mass with an internal septum. The mass was surgically removed. Histological examinations revealed that the mass was a non-neoplastic hepatic cyst. The patient had no recurrence of the cystic structure but died of acute renal failure 5 years after the surgery. This report describes the unusual case of a giant hepatic cyst with clinical signs that resolved after mass removal.

• BMB Reports
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• v.50 no.9
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• pp.460-465
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• 2017

Polycystic kidney disease (PKD) is one of the most common inherited disorders, involving progressive cyst formation in the kidney that leads to renal failure. FK506 binding protein 12 (FK506BP) is an immunophilin protein that performs multiple functions, including regulation of cell signaling pathways and survival. In this study, we determined the roles of PEP-1-FK506BP on cell proliferation and cyst formation in PKD cells. Purified PEP-1-FK506BP transduced into PKD cells markedly inhibited cell proliferation. Also, PEP-1-FK506BP drastically inhibited the expression levels of p-Akt, p-p70S6K, p-mTOR, and p-ERK in PKD cells. In a 3D-culture system, PEP-1-FK506BP significantly reduced cyst formation. Furthermore, the combined effects of rapamycin and PEP-1-FK506BP on cyst formation were markedly higher than the effects of individual treatments. These results suggest that PEP-1-FK506BP delayed cyst formation and could be a new therapeutic strategy for renal cyst formation in PKD.

• Korean Journal of Veterinary Research
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• v.10 no.2
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• pp.67-72
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• 1970

In this study, 198 cases of Korean Native Cattle having renal lesions were observed during the examination of a cases and total of 350 cases in 1967. The lesions observed were 190 cases of interstitial nephritis (54.3%) I case of atrophic kindey (0.3%), 5 cases of renal cyst (1.4%) and 2 casces of renal abscess (0.6%). The interstitial nephritis was classified into focal (73.2%), local (13.6%) and diffuse (13.5%) in type. The gross and microscopic findings for the lesions were also described and discussed.

• BMB Reports
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• v.46 no.2
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• pp.73-79
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• 2013

Polycystic kidney disease (PKD) is a common hereditary disorder which is characterized by fluid-filled cysts in the kidney. Mutation in either PKD1, encoding polycystin-1 (PC1), or PKD2, encoding polycystin-2 (PC2), are causative genes of PKD. Recent studies indicate that renal cilia, known as mechanosensors, detecting flow stimulation through renal tubules, have a critical function in maintaining homeostasis of renal epithelial cells. Because most proteins related to PKD are localized to renal cilia or have a function in ciliogenesis. PC1/PC2 heterodimer is localized to the cilia, playing a role in calcium channels. Also, disruptions of ciliary proteins, except for PC1 and PC2, could be involved in the induction of polycystic kidney disease. Based on these findings, various PKD mice models were produced to understand the roles of primary cilia defects in renal cyst formation. In this review, we will describe the general role of cilia in renal epithelial cells, and the relationship between ciliary defects and PKD. We also discuss mouse models of PKD related to ciliary defects based on recent studies.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4431-4433
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• 2012

Aim: The aim of the present study was to evaluate retrospectively histopathologically-diagnosed lesions that were detected in the kidney after radical nephrectomy for a preoperative diagnosis of kidney cancer. Methods: The medical records of 83 patients (51 male, 32 female) were included. Preoperative staging was accomplished by various methods including physical examination, blood hemography and biochemistry, abdominal ultrasonography (US), chest x-ray, abdominal computed tomography (CT) and abdominal magnetic resonance imaging (MRI). Results: Totals of 70 patients underwent radical nephrectomy and 13 nephron sparing surgery. Of the 83 patients, 70 had malignant lesions (renal cell carcinoma, squamous cell carcinoma or other malignancies) 13 had a variety of benign lesions, the most frequently detected being oncoytoma (6), angiomyolipoma (3), xanthogranulamatous pyelonephritis (2), cortical cyst (1) and chronic pyelonephritic change (1). Conclusion: It was concluded that in spite of great technological developments regarding radiological imaging modalities such as US, CT and MRI, benign lesions might still be detected pathologically in patients who undergo radical nephrectomy with the preoperative diagnosis of renal cancer. But, all renal masses should be regarded as malignant and should be managed surgically otherwise proven benign.