• The Korean Journal of Pain
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• 제32권2호
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• pp.97-104
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• 2019

Background: This study was conducted to compare the effectiveness of low-dose ketamine versus ketorolac in pain control in patients with acute renal colic presenting to the emergency department (ED). Methods: This is a double-blind randomized clinical trial. The initial pain severity was assessed using the numerical rating scale (NRS). Then, ketamine or ketorolac was administered intravenously at a dose of 0.6 mg/kg and 30 mg respectively. The pain severity and adverse drug reactions were recorded 5, 15, 30, 60, and 120 min thereafter. Results: The data of 62 subjects in the ketamine group and 64 patients in the ketorolac group were analyzed. The mean age of the patients was $34.2{\pm}9.9$ and $37.9{\pm}10.6\;years$ in the ketamine and ketorolac group, respectively. There was no significant difference in the mean NRS scores at each time point, except for the 5 min, between the two groups. Despite a marked decrease in pain severity in the ketamine group from drug administration at the 5 min, a slight increase in pain was observed from the 5 min to the 15 min. The rate of adverse drug reactions, including dizziness (P = 0.001), agitation (P = 0.002), increased systolic blood pressure (> 140 mmHg), and diastolic blood pressure (> 90 mmHg) was higher in the ketamine group. Conclusions: Low dose ketamine is as effective as ketorolac in pain management in patients with renal colic presenting to the ED. However, it is associated with a higher rate of adverse drug reactions.

• 대한영상의학회지
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• 제84권4호
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• pp.923-933
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• 2023

목적 응급실의 급성신산통을 호소하는 환자에서 피질-수질기 요로조영술 컴퓨터 단층촬영(이하 CT)에서 요로결석 발견을 기존의 CT 요로조영술과 비교하였다. 대상과 방법 이 후향적 연구는 한국의 두 삼차 병원의 응급실에서 CT 요로조영술을 촬영한 253명의 요로결석이 의심된 환자를 대상으로 시행하였다. 임상 병력을 알지 못한채로 두 명의 영상의학과 의사가 독립적으로 CT 요로조영술의 피질-수질기를 판독하여 요로결석에 관한 정보를 기록하였다. 판독자들의 요로결석 발견에 대한 민감도를 측정하였다. 초기 평가 후, 임상 정보를 바탕으로 다시 피질-수질기를 판독하였고 민감도를 측정하였다. 결과 253명 중 150명(59%)이 요로결석이 있었고, 요로결석이 응급실 방문의 원인(의미 있는 요로결석)이었던 사람은 138명(92%)이었고, 요로 폐쇄로 인한 변화를 보인 환자는 124명 (82.7%)이었다. 의미 있는 요로결석에 대해서는 두 판독자의 민감도는 98.6% (136/138)이었다. 요로 폐쇄로 인한 변화가 동반되었을 때의 민감도는 판독자 1은 99.2% (123/124)였고 판독자 2는 100% (124/124)였다. 임상 정보를 바탕으로 다시 판독했을 때 의미 있는 요로결석 발견의 민감도는 판독자 1이 98.6%에서 100%, 판독자 2는 98.6%에서 99.3%로 증가하였다. 결론 CT 요로조영술의 피질-수질기는 급성신산통으로 응급실을 내원한 환자에서 요로결석을 진단하는데 민감하다.

• 대한유전성대사질환학회지
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• 제1권1호
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• pp.18-22
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• 2001

Renal colic, hematuria, dysuria and stone passage were developed in younger brother (4 year 6 month old boy). But the elder sister (6 year old girl)had no specific symptoms and signs. The identification of the disease was proved by cyanide nitroprusside test and amino acid analysis of urine. In our patients the chromatographic amino acid patterns of urine showed remarkably increased excretion of cystine, ornithine, lysine, and arginine. They are managed by adequate hydration with Shohl solution for rendering the urine more alkaline, and alpha-mercaptopropionylglycine (Thiola).

• Journal of Preventive Medicine and Public Health
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• 제52권1호
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• pp.1-13
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• 2019

Objectives: In recent years, serious concerns have been raised regarding the impacts of rising temperatures on health. The present study was conducted to investigate the relationship between elevated temperatures and kidney disease through a systematic review and meta-analysis. Methods: In October 2017, 2 researchers independently searched related studies in PubMed and Embase. A meta-analysis was conducted using a random-effects model, including only studies that presented odds ratios, relative risks, or percentage changes, along with 95% confidence intervals (CIs). The characteristics of each study were summarized, and the Egger test and funnel plots were used to evaluate publication bias. Results: Eleven studies that met the criteria were included in the final analysis. The pooled results suggest an increase of 30% (95% CI, 20 to 40) in kidney disease morbidity with high temperatures. In a disease-specific subgroup analysis, statistically significant results were observed for both renal colic or kidney stones and other renal diseases. In a study design-specific subgroup analysis, statistically significant results were observed in both time-series analyses and studies with other designs. In a temperature measure-specific subgroup analysis, significant results were likewise found for both studies using mean temperature measurements and studies measuring heat waves or heat stress. Conclusions: Our results indicate that morbidity due to kidney disease increases at high temperatures. We also found significant results in subgroup analyses. However, further time-series analyses are needed to obtain more generalizable evidence.

• 한국임상수의학회지
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• 제41권1호
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• pp.43-48
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• 2024

A two-year-old, intact female Golden Retriever had previously been diagnosed with a portosystemic shunt (PSS) during an ultrasonographic examination at a local animal hospital. The serum biochemistry revealed elevated liver enzymes and bile acid levels. The abdominal radiographic examination revealed mild serosal detail loss and microhepatica, while abdominal ultrasonography revealed mild ascites and high-velocity flow to the caudal vena cava (CVC) suspected as a PSS. The gallbladder was not observed within the hepatic parenchyma during ultrasonography. Computed tomography (CT) revealed an absent gallbladder and dilation of the common bile duct (CBD). Dilations of the gastroduodenal, splenic, colic and renal veins were also observed. A dilated left phrenico-abdominal vein that entered the CVC was previously misinterpreted as a PSS on the ultrasound examination. Based on the imaging examinations, the dog was diagnosed with congenital gallbladder agenesis associated CBD dilation.