• Title/Summary/Keyword: Relief Rates

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Sequential treatment with transurethral resection and hormonal therapy for bladder endometriosis of vesicoureteric junction

  • Abdulelah AlAdimi;Nabil AlOdaini;Atef M. M. Darwish
    • Journal of Medicine and Life Science
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    • v.19 no.3
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    • pp.116-120
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    • 2022
  • Objective: To estimate the efficacy of sequential treatment of bladder endometriosis (BE) of the vesicoureteric junction using transurethral resection (TUR) and hormonal therapy. Design: Case report. Setting: Private multispecialty hospital. Patient: A multiparous woman presented with perimenstrual lower urinary tract symptoms, cyclic chronic pelvic pain, and left loin pain. Intervention[s]: Ultrasonography revealed marked left renal dilatation. Computed tomography confirmed the presence of a bladder mass. A diagnostic cystoscopy revealed compression of the left vesicoureteral junction. Complete TUR BE with release of chocolate material during resection, followed by ureteric double J stent insertion for 3 months, was performed. Histopathology confirmed the diagnosis of BE, followed by adjuvant hormonal therapy (dienogest) for 3 months. Follow-up for about 2 years revealed complete relief of the symptoms without any recurrence. Main Outcome Measure[s]. Success and recurrence rates of sequential TUR and hormonal therapy of BE of the vesicoureteric junction. Result[s]. TUR BE followed by adjuvant hormonal therapy was very effective in eradicating BE of the vesicoureteric junction in a safe manner without recurrence on follow-up for 2 years. Conclusion[s]. BE of the vesicoureteric junction can be properly treated by sequential TUR and hormonal therapy without recurrence over a 2-year follow-up.

Regression Models for Determining the Patent Royalty Rates using Infringement Damage Awards and Inter-Partes Review Cases (손해배상액과 무효심판 판례를 이용한 특허 로열티율 산정 회귀모형)

  • Yang, Dong Hong;Kang, Gunseog;Kim, Sung-Chul
    • The Journal of Society for e-Business Studies
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    • v.23 no.1
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    • pp.47-63
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    • 2018
  • This study suggested quantitative models to calculate a royalty rate as an important input factor of the relief from royalty method which has the characteristics of income approach method and market approach method that are generally used in the valuation of intangible assets. This study built a royalty rate regression model by referring to the patent infringement damages cases based on royalties, i.e., by using the royalty rates as a dependent variable and the patent indexes of the corresponding patent right as independent variables. Then, a logistic regression model was constructed by referring to inter-partes review cases of patent rights, i.e. by using not-unpatentable results as a dependent variable and the patent indexes of the corresponding patent right as independent variables. A final royalty rate was calculated by matching the royalty rate from the royalty rate regression model with a not-unpatentable probability from the logistic regression model. The suggested royalty rate was compared with the royalty rate obtained by the traditional methods to check its reliability.

S-Nitrosoglutathione (GSNO) Alleviates Lead Toxicity in Soybean by Modulating ROS, Antioxidants and Metal Related Transcripts

  • Methela Nusrat Jahan;Islam Mohammad Shafiqul;Da-Sol Lee;Youn-Ji Woo;Bong-Gyu Mun;Byung-Wook Yun
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2023.04a
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    • pp.105-105
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    • 2023
  • Heavy metals, including lead (Pb) toxicity, are increasing in soil and are considered toxic in small amounts. Pb contamination is mainly caused by industrialization - smelting, mining. Agricultural practices - sewage sludge, pests and urban practices - lead paint. It can seriously damage and threaten crop growth. Pb can adversely affect plant growth and development by affecting the photosystem, cell membrane integrity, and excessive production of reactive oxygen species (ROS) such as hydrogen peroxide (H2O2)andsuperoxide(O2.-). NO is produced via enzymatic and non-enzymatic antioxidants to scavenge ROS and lipid peroxidation substrates in terms of protecting cells from oxidative damage. Thus, NO improves ion homeostasis and confers resistance to metal stress. Our results here suggest that exogenous NO may aid in better growth under lead stress. These enhancements may be aided by NO's ability in sensing, signaling and stress tolerance in plants under heavy metal stress in combination with lead stress. Our results show that GSNO has a positive effect on soybean seedling growth in response to axillary pressure and that NO supplementation helps to reduce chlorophyll maturation and relative water content in leaves and roots following strong burst under lead stress. GSNO supplementation (200 µM and 100 µM) reduced compaction and approximated oxidative damage of MDA, proline and H2O2. Under plant tension, a distorted appearance was found in the relief of oxidative damage by ROS scavenging by GSNO application. In summary, modulation of these NO, PCS and prolongation of metal past reversing GSNO application confirms the detoxification of ROS induced by toxic metal rates in soybean. In summary, these NO, PCS and metal traditionally sustained rates of reverse GSNO application confirm the detoxification of ROS induced by toxic metal rates in soybean.

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Effect of Mixture of Recombinant Human Bone Morphogenic Protein-2 and Demineralized Bone Matrix in Lateral Lumbar Interbody Fusion

  • Jun Ik Son;Young-Seok Lee;Myeong Jin Ko;Seong-Hyun Wui;Seung Won Park
    • Journal of Korean Neurosurgical Society
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    • v.67 no.3
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    • pp.354-363
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    • 2024
  • Objective : This study aims to determine the optimal dose of recombinant-human bone morphogenic protein-2 (rhBMP-2) for successful bone fusion in minimally invasive lateral lumbar interbody fusion (MIS LLIF). Previous studies show that rhBMP is an effective alternative to autologous iliac crest bone graft, but the optimal dose remains uncertain. The study analyzes the fusion rates associated with different rhBMP doses to provide a recommendation for the optimal dose in MIS LLIF. Methods : Ninety-three patients underwent MIS LLIF using demineralized bone matrix (DBM) or a mixture of rhBMP-2 and DBM as fusion material. The group was divided into the following three groups according to the rhBMP-2 usage : group A, only DBM was used (n=27); group B, 1 mg of rhBMP-2 per 5 mL of DBM paste (n=41); and group C, 2 mg of rhBMP-2 per 5 mL of DBM paste (n=25). Demographic data, clinical outcomes, postoperative complication and fusion were assessed. Results : At 12 months post-surgery, the overall fusion rate was 92.3% according to Bridwell fusion grading system. Groups B and C, who received rhBMP-2, had significantly higher fusion rates than group A, who received only DBM. However, there was no significant increase in fusion rate when the rhBMP-2 dosage was increased from group B to group C. The groups B and C showed significant improvement in back pain and Oswestry disability index compared to the group A. The incidence of screw loosening was decreased in groups B and C, but there was no significant difference in the occurrence of other complications. Conclusion : Usage of rhBMP-2 in LLIF surgery leads to early and increased final fusion rates, which can result in faster pain relief and return to daily activities for patients. The benefits of using rhBMP-2 were not significantly different between the groups that received 1 mg/5 mL and 2 mg/5 mL of rhBMP-2. Therefore, it is recommended to use 1 mg of rhBMP-2 with 5 mL of DBM, taking both economic and clinical aspects into consideration.

Adverse Selection in the Korean Storm and Flood Insurance Market (국내 풍수해보험시장에서의 역선택 문제에 관한 실증분석)

  • Park, Chang-Gyun;Yeo, Eunjung
    • KDI Journal of Economic Policy
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    • v.35 no.3
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    • pp.39-63
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    • 2013
  • We use a unique survey data set of storm and flood insurance in Korea to test for adverse selection. We find systematically positive relationships between the decision to buy the insurance and the insureds' past history with, and potential for, losses from natural disasters. The empirical results suggest that consumers with higher loss rates will be more likely to purchase the insurance. This highlights the importance of considering the detailed features of insurance contracts, such as an improvement in the current insurance premium assistance program as the government amends its current policies regarding storm and flood insurance and disaster relief program.

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Comparing the Current Health Status and Health Behaviors of Residents from Urban and Forested Areas (산림 지역과 도시 지역 성인의 건강상태 및 건강행태 비교)

  • Lee, Insook;Lee, Kowoon;Kim, Sung Jae;Bang, Kyung Sook;Choi, Hee Seung
    • Perspectives in Nursing Science
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    • v.12 no.1
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    • pp.14-22
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    • 2015
  • Purpose: Forests have positive effects on health due to phytoncide, thus increasing physical activity and stress relief. However, research has not been conducted on the daily health benefits of existing forests. Therefore, this study attempts to compare the health status and behaviors of residents in urban and forested areas. Methods: This cross-sectional study used anthropometric measures, blood tests, heart rate variability, depression, stress, and health behavior self-reports for adults between 35 and 79 years from two regions. Results: Adults living in a forested region had better health consequences-including lower prevalence of osteoarthritis (6.4%) and mean bone mineral density (-0.84) -than those in an urban region (osteoarthritis: 13.7%; bone mineral density: -1.55). The percentage of 'physically active' participants (measured in MET-minutes) differed significantly different between the forested (49.1%) and urban (7.3%) areas. However, health behaviors such as smoking, alcohol consumption, and regular heath check-up rates were worse among residents from the forested, than the urban area. Conclusion: We concluded that more proactive forest therapy programs are needed to prove the health differences.

Properties of Channel and Evolutions of Fluvial Terraces in Odae River (오대천의 특성과 하안단구의 형성과정)

  • Lee, Gwang-Ryul
    • Journal of the Korean Geographical Society
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    • v.44 no.3
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    • pp.224-239
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    • 2009
  • This study analyzes the properties of fluvial landforms in the upper and lower reaches and investigates the evolutions of stream and fluvial terrace in the Odae river basin. The lower basin of the river that consist of sedimentary rocks resistant to weathering and erosion processes shows higher altitude, relief and slope than the upper basin that consist of granite less resistant to weathering and erosion processes. The average width of river valley at the lower reaches is one-third to the upper reaches and the average width of river channel at the lower reaches is narrower than at the upper reaches. Based on the OSL age dating, the fluvial terrace T1 formed at the temperature-rising period during the late MIS 2 and T2 formed at the middle MIS 3, interstadial period during the last glacial period. Based on the these results, the average incision rates of Odae river are calculated as 0.205m/ka and 0.269m/ka at the upper granite area and lower sedimentary rocks area, respectively.

Intrathecal Catheter and Subcutaneous Access Port Implantation in Pain Management for Terminal Cancer Patient - A case report - (말기암 환자의 통증치료를 위한 지주막하강내 카테터 거치와 피하 이식형 약제 주입기 삽입 - 증례보고 -)

  • Seo, Kwi Chu;Chung, Jin Yong;Kim, Ho Young;Rho, Woon Seok;Kim, Bong Il;Song, Seok Young
    • The Korean Journal of Pain
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    • v.20 no.2
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    • pp.240-245
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    • 2007
  • It is important to treat cancer-related pain in cancer patients to ensure the life quality of the patient, as well as to improve their life span. It has been estimated that at least 5% of cancer patients have pain refractory to medical treatment. Therefore, the need for epidural or intrathecal analgesia with opioids and local anesthetics is indicated if systemic treatment has failed. Intrathecal catheter placement and implantation of the injection port for administration of opioids and local anesthetics may improve pain relief in patients who are unresponsive to epidural routes. Although intrathecal implantation has several complications, similar infection rates have been reported between intrathecal and epidural administration. In addition, intrathecal administration showed better outcomes, including improved pain control, lowered daily doses, and an improvement in the level of drowsiness experienced when compared to epidural administration. We report here a case in which a terminal cancer patient was treated using an intrathecal catheter and subcutaneous port. The patient had cancer-related pain that could not be controlled by epidural opioid administration. Based on the results presented here, we suggest that intrathecal implantation is a feasible long term pain management method for intractable cancer pain patients.

Efficacy of Computerized Cognitive Behavioral Therapy in Individuals with Non-Cardiac Chest Discomfort : Review and Suggestions for a New Protocol (비심인성 흉부 불편감을 가진 대상자에서 컴퓨터 기반 인지행동치료의 효과성 : 문헌 검토와 새로운 프로토콜 제안)

  • Lyoo, In Kyoon;Kim, Jungyoon;Kim, Jieun E.
    • Korean Journal of Biological Psychiatry
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    • v.26 no.1
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    • pp.1-7
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    • 2019
  • Since non-cardiac chest discomfort (NCCD) can result in substantial healthcare burden and lower quality of life, interventions such as cognitive behavioral therapy (CBT) have been investigated for the relief of NCCD. In this review, we aimed to summarize the evidence on the efficacy of the CBT for the treatment of NCCD while introducing a newly-developed computerized CBT program for NCCD. Studies applying CBT to individuals with NCCD were searched for from both English and Korean electronic databases. Among 37 studies, 11 randomized controlled trials, 4 case-control studies, 1 case series, and 2 review articles were eligible for this review. Efficacy of conventional CBT for NCCD was shown in a series of studies as most of them reported improved symptom severity of NCCD or NCCD-related anxiety. However, a substantial variability existed among these studies in participants, treatment procedures and durations. High attrition rates were also reported in these studies on conventional CBT. Computerized CBT could be an alternative to the conventional CBT as it can be standardized and more easily accessible, but it was only reported in one previous study. In addition to the literature review, we presented a newly-developed computerized CBT program for NCCD which may overcome some of the limitations of conventional CBT. A computerized CBT could be an alternative treatment of NCCD, however, need further studies on its usefulness.

Factors Influencing Dietary Behaviors and Stress in Male and Female College Students (남녀대학생의 식행동과 스트레스 영향요인)

  • Seo, Eun-Young;Lee, Seung-Lim
    • Journal of the Korean Society of School Health
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    • v.31 no.3
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    • pp.186-195
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    • 2018
  • Purpose: This study was performed to investigate the dietary behaviors and stress-related factors among male and female college students. Methods: A total of 405 college students (male-195, female-210) were recruited, of whom a questionnaire-based survey was conducted. The study investigated the general characteristics, health-related factors, dietary behaviors, and stress-related factors of the respondents. Results: The body mass index was significantly higher in males. The rates of underweight and overweight were significantly different between male and female respondents. The scores for workout frequency, health concerns and health condition were significantly higher in males, while the score for watching TV & playing computer games was significantly higher in females. The scores for meal regularity, frequency of breakfast consumption, and smoking were significantly higher in males. Eating problems showed a significant difference between males and females. The biggest source of stress was social factors, followed by college study and individual factors and the most experienced stress-induced symptom was anxiety, followed by headache and stomachache. The most popular way to overcome stress was taking a rest, followed by drinking & smoking and outdoor activity. The most preferred food under stressful conditions were alcohol or beverages, followed by hot & spicy food and sweet food, which showed a significant difference between males and females. Conclusion: These results indicate that stress affects dietary behaviors, drinking, smoking, and health status. Stress not only changes dietary behaviors, but is also related to health status. Therefore, it is necessary to develop appropriate programs for emotional stability and stress relief targeting college students which provide continuous nutrition education focused on desirable dietary behaviors and nutritional aspects.