• 근관절건강학회지
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• 제27권3호
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• pp.289-297
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• 2020

Purpose: This descriptive study aimed to identify the foot health condition and related characteristics of nurses. Methods: A literature-based questionnaire was developed and distributed to 472 nurses in a university hospital in B city, and data were collected from August 1 to August 15, 2020. The Foot Health Status Questionnaire (FHSQ) was used to measure foot health condition. Results: The most common foot diseases among the participants were plantar fasciitis (7.8%) and hallux valgus (7.0%). To relieve foot pain, most nurses used relaxation techniques, stretching, elevating the legs, and foot massage. The level of foot health condition among nurses was lower than that of older persons or the general public with chronic foot disease. The foot health condition of the nurses showed that the lower the age and the greater the number of foot diseases, the more severe the pain and dysfunction. Conclusion: The study shows that there is a need for interventions that will raise nurses' awareness about foot health and induce better foot health management.

• Elastomers and Composites
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• 제37권4호
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• pp.234-243
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• 2002

A general scheme of a rubber structure is proposed. Using the thermomechanical method(TMA), some changes in the molecular and topological structures for uncured and cured, and unfilled and filled rubbers during processing are shown. In our investigations as region it is understood a complex structure, which is expressed at the thermomechanical curve(TMC) as a zone differed from others in thermal expansion properties. This zone is between the noticed temperatures of relaxation transitions, usually on the level like those determined by DMTA at 1Hz. These regions, which shares, are not stable, and differ in molecular-weight distribution(MWD) of chain fragments between the junctions. Differences in dynamics of the formation of the molecular and topological structures of a vulcanizate are dependent on the rubber formulation, mixing technology and curing time. Some of characteristics of these regions correlate with mechanical properties of vulcanizates what is shown for NR rubbers containing ENR or CPE as a polymeric additive. It is well known that the state of order influences diffusivity of low-molecular substances into the polymer matrix. Because of this, the two topological amorphous regions should influence the distribution of the ingredients and resulting in rubber compounds' heterogeneity, and related properties of cured rubber. Investigation of this problem is expected to be, in the future, one of the essential factors in determining further improvement of polymeric materials properties by compounding with additives and in reprocessing of rubber scrap.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2022년도 가을 학술논문 발표대회
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• pp.205-206
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• 2022

This study intends to conduct tests on subsidence and drying shrinkage by mixing CaO-CSA expansion materials to ensure the stability of CLC, and to understand its properties. Based on CLC of 0.6, the replacement ratio of CaO-CSA expansion material was conducted at five levels compared to blast furnace slag, and the results are as follows. The replacement of CaO-CSA expansion material at an appropriate level produces ethringhite and potassium hydroxide, and it is believed that the internal voids of CLC and the Tobelmorite interlayer structure are charged to increase the structural stability, leading to an increase in compressive strength and a decrease in the drying shrinkage. However, it is judged that tissue relaxation due to excessive substances in the high replacement ratio affects the stability of CLC. In the future, we will conduct additional experiments on density, absorption rate, flow test, and settlement, and evaluate and analyze the stability of CLC by selecting the optimal replacement ratio of CaO-CSA expansion materials.

• 대한약침학회지
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• 제26권4호
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• pp.366-372
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• 2023

Objectives: We aimed to evaluate the genotoxicity of a recently developed no-pain pharmacopuncture (NPP) targeting muscle relaxation and analgesia using the micronucleus test. Methods: To evaluate the potential of NPP extracts to induce micronuclei in rat bone marrow cells, a micronucleus test was performed using male Sprague-Dawley rats. The test substance NPP was administered intramuscularly at concentrations of 0.25, 0.5, and 1 mL/animal. Saline was used as the negative control and cyclophosphamide as the positive control. Results: No NPP treatment-related deaths or abnormal changes in general appearance were observed at any dose level during the experimental period. No statistically significant differences in body weight were observed in any of the NPP dose groups compared to the saline negative control group. NPP did not cause a significant increase in the incidence of micronucleated polychromatic erythrocytes (PCEs) and PCEs or in the ratio of PCE-to-total erythrocytes. Conclusion: The NPP extract did not exhibit genotoxic in Sprague-Dawley rat bone marrow cells under the conditions of this study. Further toxicity studies of the NPP extract are required.

• International Journal of Vascular Biomedical Engineering
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• 제1권2호
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• pp.13-19
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• 2003

Endothelial release of nitric oxide (NO) contributes to the regulation of vascular tone by inducing vascular relaxation. To estimate the blood flow-dependent nitric oxide level and half-life (T1/2) of nitric oxide in vivo state, we investigated the change of aortic NO currents during the change of aortic blood flow rate using NO-selective electrode system and electromagnetic flowmeter in the aorta of anesthetized rats. Resting mean aortic blood flow rate was $49.6{\pm}5.6ml/min$ in the anesthetized rats. NO currents in the aorta were increased by the elevation of blood pressure and/or blood flow rate. When the aortic blood flow was occluded by the clamping, aortic NO currents were decreased. The difference of NO concentration between resting state and occluded state was $1.34{\pm}0.26{\mu}M$ (n=7). This NO concentration was estimated as blood flow-dependent nitric oxide concentration in the rats. Also, while the aortic blood flow was occluded, NO currents were decreased with exponential pattern with $12.84{\pm}2.15$ seconds of time constant and $7.70{\pm}1.07$ seconds of half-life. To summarize, this study suggested that blood flow-dependent NO concentration and half-life of nitric oxide were about $1.3{\mu}M$ and 7.7 seconds, respectively, in the aorta of anesthetized rats. The nitric oxide-selective electrode system is useful for the direct and continuous measurement of NO in vivo state.

• Journal of Oral Medicine and Pain
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• 제18권2호
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• pp.97-106
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• 1993

This study was performed to investigate the effects of infrared and visible light laser irradiation on cell viability of human gingival fibroblast. For the present study, the author used cultured fibroblast originated from sound gingiva which were fifth of sixth passage. Laser machine utilized here were stomalaser which irradiate infrared (GaAs diode) and red (HeNe) laser in turn with pulse wave pattern or continuous wave pattern, and the machine had several frequency mode presented by regeneration, relaxation and analgesic modalities. Cultured fibroblast samples were divided by this modalities of cell counts and laser exposure time which were 7-seconds of 150 seconds, respectively. 1 day after laser irradiation, each cell-well was treated with MTT and measured optical density with ELISA. The obtained results were as follows : 1. There was a tendency of increasing optical density in proportion to irradiation time in groups of $1\times10^4$ cell per well but in groups of $5\times10^3$ cell per well, reverse phenomena were observed. 2. The difference of optical density according to frequency modalities were not showed significantly except several cases in groups of $5\times10^3$ cell per well. 3. In general, cell viability of cultured human gingival fibroblast wer not showed consistent feature by low level laser irradiation.

• 한국콘텐츠학회논문지
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• 제11권4호
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• pp.42-50
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• 2011

생체신호인 뇌파를 이용하여 이러닝 학습자의 학습태도를 파악하고 그에 따른 적절한 피드백을 제공하여 학습자의 학습효율을 극대화하려는 연구의 일환으로 여대생을 대상으로 학습자의 학습태도와 뇌파를 분석하여 이들의 상관관계를 밝혀보고자 한다. 학습자가 학습에 집중하는 태도와 그렇지 않은 태도에 대해 뇌파의 파워 스펙트럼을 추출하여 학습자의 뇌파가 어떻게 반응하는지에 중점을 두어 연구하였다. 학습에 집중하는 태도의 대조군으로 산만한 태도와 눈감은 태도를 설정하여 실험을 진행하였다. 학습에 집중하는 태도에서는 집중도가 산만한 태도에 비하여 높게 나타나고 이완지표는 낮게 나타나며, 클릭과 눈굴림과 같은 산만한 태도에서는 주의지표와 잡파 비율이 높게 나왔다. 특히, 눈을 감았을 때는 알파 세타 비율이 1이하로 나타나 눈을 뜬 다른 상태와 뚜렷이 구분되었다.

• 한국환경과학회지
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• 제19권4호
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• pp.427-436
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• 2010

In this study this author made research and analysis on physical status and characteristics of community parks in Ik-san provinces and also depending on its potential resources such parks were classified into constructed parks and unconstructed parks and status of use of such parks and level of satisfaction were studied. Through this paper this author strived to provide basic data required for forming green track of land for the parks. Required time for visiting community parks either constructed or unconstructed type was within 40 minutes or less. However constructed parks appeared to be more convenient for access in comparison with natural unconstructed parks. Mostly they were used by residents in neighboring community and also residents in the area around it were found as using it frequently. At the time of using community parks either constructed or unconstructed types means of access were mostly by walking or by riding bicycles. Thus considering large number of users of such parks are from neighboring community it appeared that parks with its simplicity and convenience in terms of distance and with rich nature were preferred by users rather than large scale parks at distance. In terms of time frame of use and motivation of visit constructed parks were used mainly for exercise and relaxation in the morning at parks and its facilities whereas un constructed parks were mostly used in the afternoon for for walking and chatting and rest under with time to spare at shadows of its trees. Time spent at parks were composed mostly of rest and walking more frequently than exercise and leisure activity thus it was different from motivation for visiting parks. As for evaluation of use of parks natural elements, unique environment, trees and lawns featured highly in unconstructed parks in comparison with constructed parks. Thus it seemed visitors are more conscious of forest and landscape in a form of unchanged nature. Thus for community parks first consideration should be heightening accessibility in view of primary concern for convenience by users rather than facilities or environmental conditions.

• The Korean Journal of Physiology and Pharmacology
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• 제4권6호
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• pp.479-486
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• 2000

The aim of this study was to clarify the mechanism of the inhibitory action of carbon monoxide (CO) on contraction, by measuring cytosolic $Ca^{2+}$ level $([Ca^{2+}]_i)$ and ionic currents in guinea-pig ileum. CO (10%) inhibited 40 mM KCl-induced contraction and this effect was blocked by ODQ $(1\;{\mu}M),$ a soluble guanylyl cyclase (sGC) inhibitor. CO inhibited the 40 mM KCl-induced contraction without changing $[Ca^{2+}]_i.$ Cumulative addition of KCl induced a graded increase in $[Ca^{2+}]_i$ and muscle tension. In the presence of CO, cumulative addition of KCl induced smaller contraction than in the absence of CO. On the other hand, the increase in $[Ca^{2+}]_i$ induced by cumulative addition of KCl was only slightly decreased in the presence of CO, and the $[Ca^{2+}]_i-tension$ relationship shifted downwards. Using the patch clamp technique with a holding potential of -60 mV, we found that CO had little effect on the peak Ba currents $(I_{Ba})$ when voltage was stepped from -60 mV to 0 mV. In addition, CO showed no effect on the depolarization-activated outward $K^+$ currents in the all potential ranges. We conclude that CO inhibits smooth muscle contraction mainly by decreasing the $Ca^{2+}$ sensitivity of contractile elements via a cGMP-dependent pathway, not by involving L-type $Ca^{2+}$ and outward-potassium currents in guinea-pig ileum.

• Biomolecules & Therapeutics
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• 제26권2호
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• pp.139-145
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• 2018

The present study was undertaken to investigate the influence of hypothermia on endothelium-independent vascular smooth muscle contractility and to determine the mechanism underlying the relaxation. Denuded aortic rings from male rats were used and isometric contractions were recorded and combined with molecular experiments. Hypothermia significantly inhibited fluoride-, thromboxane $A_{2-}$, phenylephrine-, and phorbol ester-induced vascular contractions regardless of endothelial nitric oxide synthesis, suggesting that another pathway had a direct effect on vascular smooth muscle. Hypothermia significantly inhibited the fluoride-induced increase in pMYPT1 level and phorbol ester-induced increase in pERK1/2 level, suggesting inhibition of Rho-kinase and MEK activity and subsequent phosphorylation of MYPT1 and ERK1/2. These results suggest that the relaxing effect of moderate hypothermia on agonist-induced vascular contraction regardless of endothelial function involves inhibition of Rho-kinase and MEK activities.