• Title/Summary/Keyword: Relative risks

Search Result 225, Processing Time 0.03 seconds

Evaluation of Obstructive Pulmonary Function Impairment Risks in Pulmonary Emphysema Detected by Low-Dose CT: Compared with Simple Digital Radiography (단순 디지털 촬영과 저선량 CT의 폐기종 소견으로부터 폐쇄성 폐기능 장애 위험 비교)

  • Lee, Won-Jeong;Lee, Jeong-Oh;Choi, Byung-Soon
    • Tuberculosis and Respiratory Diseases
    • /
    • v.71 no.1
    • /
    • pp.37-45
    • /
    • 2011
  • Background: Pulmonary emphysema (PE) is major cause of obstructive pulmonary function impairment (OPFI), which is diagnosed by spirometry. PE by high resolution CT is known to be correlated with OPFI. Recently, low dose CT (LDCT) has been increasingly used for screening interstitial lung diseases including PE. The aim of this study was to evaluate OPFI risks of subjects with PE detected by LDCT compared with those detected by simple digital radiography (SDR). Methods: LDCT and spirometry were administered to 266 inorganic dust exposed retired workers, from May 30, 2007 to August 31, 2008. This study was approved by our institutional review board and informed consent was obtained. OPFI risk was defined as less than 0.7 of forced expiratory volume in one second (FEV1)/forced vital capacity (FVC), and relative risk (RR) of OPFI of PE was calculated by multiple logistic regression analysis. Results: Of the 266 subjects, PE was found in 28 subjects (10.5%) by LDCT and in 11 subjects (4.1%) by SDR; agreement was relatively low (kappa value=0.32, p<0.001). FEV1 and FEV1/FVC were significantly different between PE and no PE groups determined by either SDR or LDCT. The differences between groups were larger when the groups were divided by the findings of SDR. When PE was present in either LDCT or SDR assays, the RRs of OPFI were 2.34 and 8.65, respectively. Conclusion: LDCT showed significantly higher sensitivity than SDR for detecting PE, especially low grade PE, in which pulmonary function is not affected. As a result, the OPFI risks in the PE group by LDCT was lower than that in the PE group by SDR.

Analysis of Fire Scenarios and Evaluation of Risks that might Occur in Operation Stage of CAES Storage Cavern (CAES 저장 공동 운영단계에서 발생 가능한 리스크 평가 및 화재 시나리오 분석)

  • Yoon, Yong-Kyun;Ju, Eun-Hye;Seo, Saem-Mul;Choi, Byung-Hee
    • Tunnel and Underground Space
    • /
    • v.25 no.1
    • /
    • pp.107-114
    • /
    • 2015
  • This study focuses on assessing risks which might occur in operation stage of CAES storage cavern and analyzing fire scenarios for the risk that have been assessed with highest risk level. Risks in operation stage were categorized into upper risk group and lower risk group. Components of upper risk group are technical risk, facility risk and natural disaster risk. Lower risk group is composed of 11 sub-risks. 20 experts were chosen to survey questionnaires. ANP model was applied to analyze the relative importance of 11 sub-risks. Results of risk analysis were compared with risk criterion to set risk priorities, and the highest risk was determined to be 'occurrence of the fire within the management opening'. Three fire scenarios were developed for the highest risk level and FDS (Fire dynamics Simulator) was used to analyze these scenarios. No. 3 scenario which air blows from tunnel into outside atmosphere represented that a rate of smoke spread was the fastest among three fire scenarios and a smoke descended most quickly below the limit line of breathing. Thus, No. 3 scenario turned out to be the most unfavorable condition when operating staffs were evacuated from access tunnel.

A Cross-check based Vulnerability Analysis Method using Static and Dynamic Analysis (정적 및 동적 분석을 이용한 크로스 체크기반 취약점 분석 기법)

  • Song, Jun-Ho;Kim, Kwang-Jik;Ko, Yong-Sun;Park, Jae-Pyo
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.19 no.12
    • /
    • pp.863-871
    • /
    • 2018
  • Existing vulnerability analysis tools are prone to missed detections, incorrect detections, and over-detection, which reduces accuracy. In this paper, cross-checking based on a vulnerability detection method using static and dynamic analysis is proposed, which develops and manages safe applications and can resolve and analyze these problems. Risks due to vulnerabilities are computed, and an intelligent vulnerability detection technique is used to improve accuracy and evaluate risks under the final version of the application. This helps the development and execution of safe applications. Through incorporation of tools that use static analysis and dynamic analysis techniques, our proposed technique overcomes weak points at each stage, and improves the accuracy of vulnerability detection. Existing vulnerability risk-evaluation systems only evaluate self-risks, whereas our proposed vulnerability risk-evaluation system reflects the vulnerability of self-risk and the detection accuracy in a complex fashion to evaluate relative. Our proposed technique compares and analyzes existing analysis tools, such as lists for detections and detection accuracy based on the top 10 items of SANS at CWE. Quantitative evaluation systems for existing vulnerability risks and the proposed application's vulnerability risks are compared and analyzed. We developed a prototype analysis tool using our technique to test the application's vulnerability detection ability, and to show that our proposed technique is superior to existing ones.

Application of Bayesian Multilevel Space-Time Models to Study Relative Risk of Esophageal Cancer in Iran 2005-2007 at a County Level

  • Rastaghi, Sedigheh;Jafari-Koshki, Tohid;Mahaki, Behzad
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.14
    • /
    • pp.5787-5792
    • /
    • 2015
  • Background: Reported age standardized incidence rates for esophageal cancer in Iran are 0.88 and 6.15 for females and males, at fifth and the eighth ranks, respectively, of cancers overall. The present study aimed to map relative risk using more realistic and less problematic methods than common estimators. Materials and Methods: In this ecological investigation, the studied population consisted of all esophageal cancer patients in Iran from 2005 to 2007. The Bayesian multilevel space-time model with three levels of county, province, and time was used to measure the relative risk of esophageal cancer. Analyses were conducted using R package INLA. Results: The total number of registered patients was 7,160. According to the results, the three-level model with adjustment for risk factors of physical activity and smoking had the best fit among all models. The overall temporal trend was significantly increasing. At county level, Ahar, Marand, Salmas, Bojnoord, Saghez, Sarakhs, Shahroud and Torbatejam had the highest relative risks. Physical activity was found to have significant direct association with risk of developing esophageal cancer. Conclusions: Given to great variation across geographical areas, many different factors affect the incidence of esophageal cancer. Conducting further studies at the individual level in areas with high incidence could provide more detailed information on risk factors of esophageal cancer.

A Study on the continuous Intention of MyData Service Users Based on the Innovation Resistance Model (혁신저항모형에 기반한 마이데이터 서비스 사용자의 지속사용의도에 관한 연구)

  • Haengnam Sung;Taeho Hong;Taewon Lee
    • Journal of Korea Society of Industrial Information Systems
    • /
    • v.29 no.2
    • /
    • pp.101-117
    • /
    • 2024
  • The purpose of this study is to consider the characteristics perceived by users who utilize MyData services in the financial sector. It aims to examine how these factors influence users' understanding for sustained usage and their resistance to innovation. The research seeks to explore the relationship between users' awareness of characteristics and its impact on both enhancing comprehension for continued usage and addressing users' resistance to innovation. Utilizing a specialized survey agency, we examined the relative effects of innovation resistance factors, such as relative advantage, perceived risks, complexity, clarity and perceived ease of use on MyData service users. Furthermore, this research focuses on employing empirical analysis to validate the relationships between these factors through the survey. The findings of this study suggest that MyData service should dedicate ongoing efforts to minimize user resistance to service utilization. Specifically, it was revealed that among the innovation resistance factors, perceived ease of use, relative advantage, perceived risk, and complexity exert influence in that order.

A Meta-Analysis of Air Pollution in Relation to Daily Mortality in Seven Major Cities of Korea, 1998-2001 (메타분석을 적용한 전국 7개 대도시의 대기오염과 일일사망발생의 상관성 연구(1998년$\sim$2001년))

  • Cho, Yong-Sung;Lee, Jong-Tae;Son, Ji-Young;Kim, Yoon-Shin
    • Journal of Environmental Health Sciences
    • /
    • v.32 no.4 s.91
    • /
    • pp.304-315
    • /
    • 2006
  • This study is performed to reexamine the association between ambient air pollution and daily mortality in seven major cities of Korea using a method of meta-analysis with the data filed for the period 1998-2001. These cities account for half of the Korean population (about 23 million). The observed concentrations of carbon monoxide (CO, mean=1.08 ppm), ozone ($O_3$, mean=33.97 ppb), particulate matter less than 10 ${\mu}m$ ($PM_{10},\;mean=57.11\;{\mu}g/m^3$), nitrogen dioxide ($NO_2$, mean=25.09 ppb), and sulfur dioxide ($SO_2$, mean=9.14 ppb) during the study period were at levels below Korea's current ambient air quality standards. Generalized additive models were applied to allow for the highly flexible fitting of seasonal and long-term time trends in air pollution as well as nonlinear associations with weather variables, such as air temperature and relative humidity. Also, we calculated a weighted mean as a meta-analysis summary of the estimates and its standard error. In city-specific analyses, an increase of $41.17{\mu}g/m^3(IQR)\;of\;PM_{10}$ corresponded to $1{\sim}12%$ more deaths, given constant weather conditions. Like most of air pollution epidemiologic studies, this meta-analysis cannot avoid fleeing from measurement misclassification since no personal measurement was taken. However, we can expect that a measurement bias be reduced in district-specific estimate since a monitoring station is better representative of air quality of the matched district. Significant heterogeneity was found for the effect of all pollutants. The estimated relative risks from meta-like analysis increased compared to those relative risks from pooled analysis. The similar results to those from the previous studies indicated existence of health effect of air pollution at current levels in many industrialized countries, including Korea.

Famine exposure in early life and type 2 diabetes in adulthood: findings from prospective studies in China

  • Feng Ning ;Jing Zhao ;Lei Zhang ;Weijing Wang ;Xiaohui Sun ;Xin Song ;Yanlei Zhang ;Hualei Xin ;Weiguo Gao;Ruqin Gao ;Dongfeng Zhang ;Zengchang Pang
    • Nutrition Research and Practice
    • /
    • v.17 no.4
    • /
    • pp.780-788
    • /
    • 2023
  • BACKGROUND/OBJECTIVES: This study examined the relationship between famine exposure in early life and the risk of type 2 diabetes in adulthood during the 1959-1961 Chinese Famine. SUBJECTS/METHODS: A total of 3,418 individuals aged 35-74 years free of diabetes from two studies in 2006 and 2009 were followed up prospectively in 2009 and 2012, respectively. Famine exposure was classified as unexposed (individuals born in 1962-1978), fetal exposed (individuals born in 1959-1961), child exposed (individuals born in 1949-1958), and adolescent/adult exposed (born in 1931-1948). A logistic regression model was used to assess the relationship between famine exposure and diabetes after adjustment for potential covariates. RESULTS: During a three-year follow-up, the age-adjusted incidence rates of type 2 diabetes were 5.7%, 14.5%, 12.7%, and 17.8% in unexposed, fetal-exposed, child-exposed, and adolescent/adult-exposed groups, respectively (P < 0.01). Relative to the unexposed group, the relative risks (95% confidence interval) for diabetes were 2.15 (1.29-3.60), 1.53 (0.93-2.51), and 1.65 (0.75-3.63) in the fetal-exposed, child-exposed, and adolescent/adult-exposed groups, after controlling for potential covariates. The interactions between famine exposure and obesity, education level, and family history of diabetes were not observed, except for the urbanization type. Individuals living in rural areas with fetal and childhood famine exposure were at a higher risk of type 2 diabetes, with relative risks of 8.79 (1.82-42.54) and 2.33 (1.17-4.65), respectively. CONCLUSIONS: These findings indicate that famine exposure in early life is an independent predictor of type 2 diabetes, particularly in women. Early identification and intervention may help prevent diabetes in later life.

Health Inequalities in Korea: Current Conditions and Implications (한국 건강불평등의 현황과 문제점)

  • Kim, Yu-Mi;Kim, Myoung-Hee
    • Journal of Preventive Medicine and Public Health
    • /
    • v.40 no.6
    • /
    • pp.431-438
    • /
    • 2007
  • Objectives : The aim of this study is to summarize the current conditions and implications of health inequalities in South Korea. Methods : Through a literature review of empirical studies and supplementary analysis of the data presented in the 1998, 2001, and 2005 KNHANEs, we evaluated the extent and trends of socioeconomic inequalities in both health risk factors, such as smoking, physical activity, and obesity, and outcomes, such as total mortality, subjective poor health status by self-reports and metabolic syndrome. Relative risks and odds ratios were used to measure differences across socioeconomic groups, and the relative index of inequality was used to evaluate the changes in inequalities over time. Results : We found clear inequalities to various degrees?in most health indicators. While little change was observed in mortality differences over time, the socioeconomic gaps in risk factors and morbidity have been widening, with much larger differences among the younger population. Conclusions : Socioeconomic inequalities are pervasive across various health indicators, and some of them are increasing. The trends in socioeconomic inequalities in health should be carefully monitored, and comprehensive measures to alleviate health inequalities are needed, especially for young populations.

Non-organ Specific Cancer Preventive Effect of Korean Ginseng : A Prospective Study for 10 Years

  • Yun, Taik-Koo;Choi, Soo-Yong
    • Proceedings of the Ginseng society Conference
    • /
    • 1998.06a
    • /
    • pp.174-181
    • /
    • 1998
  • A prospective study was conducted to evaluate the preventive effect of Korean ginseng against cancer in the population residing ginseng cultivation area, Kangwha-eup from August 1987 to December 1997. The participants consisted of 4,553 adults over 40 years old who completed a questionare on ginseng intake. During the surveillance period, 14.4% (656 of 4,553) of subjects had died, cancer accounting for 23.9% (157) of total deaths. The proportional hazard model of Cox was used to estimate relative risks when controlling simultaneously for covariates. Ginseng intakers had a decreased risk (relative risk(RR) =0.48, 95% confidence interval (Cl) : 0.34-0.66) for cancer compared with non-intakers. The RRs of cancer were 0.36 (95% Cl: 0.24-0.56) for multiple combination intakers. Among 24 red ginseng intakers, there were no cancer deaths. The RRs of ginseng intakers were 0.38 (95% Cl: 0.20-0.71) in gastric cancer and 0.29 (95% Cl: 0.15- 0.57) in lung cancer. These findings strongly suggested Korean ginseng have non-organ specific cancer preventive effects against cancer. Further research for clarifying the mechanisms of prevention and clinical trials on Korean ginseng must be conducted with worldwide collaborations

  • PDF

The Effects of a Sexual Abuse Prevention Program on the Children's Perceptions of the Risks of Sexual Abuse (성학대 예방 프로그램이 아동의 성학대 위험 지각에 미치는 효과)

  • Lee, Mi Kyoung;Lee, Jae Yeon
    • Korean Journal of Child Studies
    • /
    • v.19 no.1
    • /
    • pp.193-209
    • /
    • 1998
  • The present study assessed children's perceptions of risk of sexual abuse before and after participation in a sexual abuse prevention program, and investigated the effects of the sexual abuse prevention program on the children's emotional response. The subjects for this study were 135 3rd and 145 6th graders, attending elementary school in Seoul. Instruments were the Sexual Abuse Situational Risk (Jacobs, Hashima, & Kenning, 1995) and the Children's Emotional Response Questionnaire (Garbarino, 1987). The results of this study were that (1) children's perceptions of the risk of sexual abuse by a stranger decreased, relative to those by familiar persons which increased after the program. Especially, 6th graders had higher perceptions of the likelihood of abuse by familiar persons than 3rd graders. Girls had higher perceptions of risk than boys. (2) Children perceived adults as more dangerous than adolescents both before-and after-program. (3) Children's perceptions of the risk of sexual abuse in public settings decreased, relative to perceptions of risk in private settings which increased after the program. Girls had higher perceptions of the liklihood of abuse in private settings than boys; no significant difference was found by grade. (4) Children's emotional response did not reveal a significant change between pretest and posttests.

  • PDF