• Tuberculosis and Respiratory Diseases
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• 제71권1호
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• pp.37-45
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• 2011

Background: Pulmonary emphysema (PE) is major cause of obstructive pulmonary function impairment (OPFI), which is diagnosed by spirometry. PE by high resolution CT is known to be correlated with OPFI. Recently, low dose CT (LDCT) has been increasingly used for screening interstitial lung diseases including PE. The aim of this study was to evaluate OPFI risks of subjects with PE detected by LDCT compared with those detected by simple digital radiography (SDR). Methods: LDCT and spirometry were administered to 266 inorganic dust exposed retired workers, from May 30, 2007 to August 31, 2008. This study was approved by our institutional review board and informed consent was obtained. OPFI risk was defined as less than 0.7 of forced expiratory volume in one second (FEV1)/forced vital capacity (FVC), and relative risk (RR) of OPFI of PE was calculated by multiple logistic regression analysis. Results: Of the 266 subjects, PE was found in 28 subjects (10.5%) by LDCT and in 11 subjects (4.1%) by SDR; agreement was relatively low (kappa value=0.32, p<0.001). FEV1 and FEV1/FVC were significantly different between PE and no PE groups determined by either SDR or LDCT. The differences between groups were larger when the groups were divided by the findings of SDR. When PE was present in either LDCT or SDR assays, the RRs of OPFI were 2.34 and 8.65, respectively. Conclusion: LDCT showed significantly higher sensitivity than SDR for detecting PE, especially low grade PE, in which pulmonary function is not affected. As a result, the OPFI risks in the PE group by LDCT was lower than that in the PE group by SDR.

• 터널과지하공간
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• 제25권1호
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• pp.107-114
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• 2015

본 연구에서는 CAES 저장 공동의 운영단계에서 발생할 가능성이 있는 리스크를 분석 및 평가하고, 가장 높은 리스크 수준을 가지고 있는 것으로 판명된 리스크에 대해서 화재 시나리오를 작성하였다. 운영단계에서의 리스크를 상위 리스크와 하위 리스크로 구분하였다. 상위 리스크는 '기술적 리스크', '시설 리스크', '자연재해 리스크'로 이루어져 있으며, 하위 리스크는 11개의 리스크 요인들로 구성되어 있다. 20인의 관련 분야 전문가에게 설문 조사를 실시하였으며, 설문 내용을 분석하기 위해서 ANP 모델을 적용하였다. 리스크 우선순위를 결정하기 위해서 ANP 분석 결과와 기 결정된 리스크 평가기준을 비교하였으며, 그 결과 '관리공동 내 화재 발생'이 위험도가 가장 높은 리스크로 선정되었다. '관리공동 내 화재 발생' 리스크가 미치는 영향을 평가하기 위하여 시나리오를 작성한 후 분석하였다. 3가지 종류의 시나리오를 고려하였으며, 시나리오를 분석하기 위해서 FDS 화재 해석 프로그램을 사용하였다. 해석 결과 터널 내부에서 외부로 바람이 부는 경우를 가정한 No. 3 시나리오가 연기 확산 속도가 가장 크면서 가장 빠르게 연기가 호흡 한계선 이하까지 하강하는 것으로 나타났다. 따라서 운영요원이 접근터널에서 피난하는 경우 No. 3 시나리오가 가장 불리한 조건으로 판명되었다.

• 한국산학기술학회논문지
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• 제19권12호
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• pp.863-871
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• 2018

본 논문에서는 기존의 취약점 분석 도구들의 미탐지, 오탐지, 과탐지를 발생시켜 정확한 취약점 탐지를 어렵게 하는 문제점을 해결하고 분석 대상이 되는 어플리케이션의 위험도를 평가하여 안전한 어플리케이션을 개발하거나 관리할 수 있는 정적 및 동적 분석을 이용한 크로스 체크기반의 취약점 탐지 기법을 제안한다. 또한 각각의 취약점이 가지고 있는 자체 위험도를 계산하고 정확도를 높인 취약점 탐지 기법을 바탕으로 최종적인 어플리케이션의 위험도를 평가, 제시함으로서 안전한 어플리케이션의 개발 및 운영을 돕는다. 제안하는 기법은 정적 분석 및 동적 분석 기법을 사용하는 도구들의 상호작용을 통해 각 기법의 단점들을 극복하여 취약점 탐지 정확도를 향상시킨다. 또한 기존의 취약점 위험도평가 시스템은 취약점 자체 위험도에 대해서만 평가하였으나, 제안하는 위험도 평가는 취약점 자체 위험도와 탐지 정확도를 복합적으로 반영하여 어플리케이션이 얼마나 위험에 노출되어 있는지를 평가한다. 제안하는 기법은 CWE에서 SANS top 25의 상위 10위 항목을 기준으로 기존의 분석 도구들과 탐지 가능한 목록, 탐지 정확도를 비교분석하였으며, 기존의 취약점 위험도에 대한 정량적 평가 시스템과 제안하는 어플리케이션 위험도 평가 결과를 비교 분석 및 평가하였다. 제안하는 기법으로 프로토타입 분석 툴을 구현하여 실험을 통해 어플리케이션의 취약점을 분석하였을 때, 기존의 분석 도구들의 취약점 탐지 능력보다 우수한 것으로 나타났다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5787-5792
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• 2015

Background: Reported age standardized incidence rates for esophageal cancer in Iran are 0.88 and 6.15 for females and males, at fifth and the eighth ranks, respectively, of cancers overall. The present study aimed to map relative risk using more realistic and less problematic methods than common estimators. Materials and Methods: In this ecological investigation, the studied population consisted of all esophageal cancer patients in Iran from 2005 to 2007. The Bayesian multilevel space-time model with three levels of county, province, and time was used to measure the relative risk of esophageal cancer. Analyses were conducted using R package INLA. Results: The total number of registered patients was 7,160. According to the results, the three-level model with adjustment for risk factors of physical activity and smoking had the best fit among all models. The overall temporal trend was significantly increasing. At county level, Ahar, Marand, Salmas, Bojnoord, Saghez, Sarakhs, Shahroud and Torbatejam had the highest relative risks. Physical activity was found to have significant direct association with risk of developing esophageal cancer. Conclusions: Given to great variation across geographical areas, many different factors affect the incidence of esophageal cancer. Conducting further studies at the individual level in areas with high incidence could provide more detailed information on risk factors of esophageal cancer.

• 한국산업정보학회논문지
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• 제29권2호
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• pp.101-117
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• 2024

본 연구에서는 금융 분야에서 마이데이터 서비스를 이용하는 사용자가 인식하는 특성을 고려하여 지속적인 사용에 대한 이해와 혁신저항에 어떠한 영향을 미치는지를 목적으로 둔다. 또한 사용자 특성에 대한 인식과 지속적인 사용에 대한 이해력을 높이고 혁신에 대한 사용자의 저항을 해결하는데 미치는 영향에 대한 관계를 탐구하고자 한다. 이를 위해 전문설문기관을 통해 상대적 이점, 인지된 위험, 복잡성, 신뢰성, 인지된 용이성, 신뢰성 등 혁신저항 요인의 상대적인 영향을 조사였으며, 요인간의 관계를 실증분석을 통해 살펴본다. 본 연구의 결과에 따르면 마이데이터 서비스에 대한 저항을 최소화하기 위한 노력을 기울여야 하며, 특히 혁신저항 요인들 중 인지된 용이성, 상대적 이점, 인지된 위험, 복잡성 순으로 영향을 미치는 것으로 나타났다. 혁신저항을 낮추기 위해서는 인지된 용이성의 강화, 상대적 이점 감소, 위험과 복잡성에 대한 인식 관리가 필수적이라 할 수 있다.

• 한국환경보건학회지
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• 제32권4호
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• pp.304-315
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• 2006

This study is performed to reexamine the association between ambient air pollution and daily mortality in seven major cities of Korea using a method of meta-analysis with the data filed for the period 1998-2001. These cities account for half of the Korean population (about 23 million). The observed concentrations of carbon monoxide (CO, mean=1.08 ppm), ozone ($O_3$, mean=33.97 ppb), particulate matter less than 10 ${\mu}m$ ($PM_{10},\;mean=57.11\;{\mu}g/m^3$), nitrogen dioxide ($NO_2$, mean=25.09 ppb), and sulfur dioxide ($SO_2$, mean=9.14 ppb) during the study period were at levels below Korea's current ambient air quality standards. Generalized additive models were applied to allow for the highly flexible fitting of seasonal and long-term time trends in air pollution as well as nonlinear associations with weather variables, such as air temperature and relative humidity. Also, we calculated a weighted mean as a meta-analysis summary of the estimates and its standard error. In city-specific analyses, an increase of $41.17{\mu}g/m^3(IQR)\;of\;PM_{10}$ corresponded to $1{\sim}12%$ more deaths, given constant weather conditions. Like most of air pollution epidemiologic studies, this meta-analysis cannot avoid fleeing from measurement misclassification since no personal measurement was taken. However, we can expect that a measurement bias be reduced in district-specific estimate since a monitoring station is better representative of air quality of the matched district. Significant heterogeneity was found for the effect of all pollutants. The estimated relative risks from meta-like analysis increased compared to those relative risks from pooled analysis. The similar results to those from the previous studies indicated existence of health effect of air pollution at current levels in many industrialized countries, including Korea.

• Nutrition Research and Practice
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• 제17권4호
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• pp.780-788
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• 2023

BACKGROUND/OBJECTIVES: This study examined the relationship between famine exposure in early life and the risk of type 2 diabetes in adulthood during the 1959-1961 Chinese Famine. SUBJECTS/METHODS: A total of 3,418 individuals aged 35-74 years free of diabetes from two studies in 2006 and 2009 were followed up prospectively in 2009 and 2012, respectively. Famine exposure was classified as unexposed (individuals born in 1962-1978), fetal exposed (individuals born in 1959-1961), child exposed (individuals born in 1949-1958), and adolescent/adult exposed (born in 1931-1948). A logistic regression model was used to assess the relationship between famine exposure and diabetes after adjustment for potential covariates. RESULTS: During a three-year follow-up, the age-adjusted incidence rates of type 2 diabetes were 5.7%, 14.5%, 12.7%, and 17.8% in unexposed, fetal-exposed, child-exposed, and adolescent/adult-exposed groups, respectively (P < 0.01). Relative to the unexposed group, the relative risks (95% confidence interval) for diabetes were 2.15 (1.29-3.60), 1.53 (0.93-2.51), and 1.65 (0.75-3.63) in the fetal-exposed, child-exposed, and adolescent/adult-exposed groups, after controlling for potential covariates. The interactions between famine exposure and obesity, education level, and family history of diabetes were not observed, except for the urbanization type. Individuals living in rural areas with fetal and childhood famine exposure were at a higher risk of type 2 diabetes, with relative risks of 8.79 (1.82-42.54) and 2.33 (1.17-4.65), respectively. CONCLUSIONS: These findings indicate that famine exposure in early life is an independent predictor of type 2 diabetes, particularly in women. Early identification and intervention may help prevent diabetes in later life.

• Journal of Preventive Medicine and Public Health
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• 제40권6호
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• pp.431-438
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• 2007

Objectives : The aim of this study is to summarize the current conditions and implications of health inequalities in South Korea. Methods : Through a literature review of empirical studies and supplementary analysis of the data presented in the 1998, 2001, and 2005 KNHANEs, we evaluated the extent and trends of socioeconomic inequalities in both health risk factors, such as smoking, physical activity, and obesity, and outcomes, such as total mortality, subjective poor health status by self-reports and metabolic syndrome. Relative risks and odds ratios were used to measure differences across socioeconomic groups, and the relative index of inequality was used to evaluate the changes in inequalities over time. Results : We found clear inequalities to various degrees?in most health indicators. While little change was observed in mortality differences over time, the socioeconomic gaps in risk factors and morbidity have been widening, with much larger differences among the younger population. Conclusions : Socioeconomic inequalities are pervasive across various health indicators, and some of them are increasing. The trends in socioeconomic inequalities in health should be carefully monitored, and comprehensive measures to alleviate health inequalities are needed, especially for young populations.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1998년도 Advances in Ginseng Research - Proceedings of the 7th International Symposium on Ginseng -
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• pp.174-181
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• 1998

A prospective study was conducted to evaluate the preventive effect of Korean ginseng against cancer in the population residing ginseng cultivation area, Kangwha-eup from August 1987 to December 1997. The participants consisted of 4,553 adults over 40 years old who completed a questionare on ginseng intake. During the surveillance period, 14.4% (656 of 4,553) of subjects had died, cancer accounting for 23.9% (157) of total deaths. The proportional hazard model of Cox was used to estimate relative risks when controlling simultaneously for covariates. Ginseng intakers had a decreased risk (relative risk(RR) =0.48, 95% confidence interval (Cl) : 0.34-0.66) for cancer compared with non-intakers. The RRs of cancer were 0.36 (95% Cl: 0.24-0.56) for multiple combination intakers. Among 24 red ginseng intakers, there were no cancer deaths. The RRs of ginseng intakers were 0.38 (95% Cl: 0.20-0.71) in gastric cancer and 0.29 (95% Cl: 0.15- 0.57) in lung cancer. These findings strongly suggested Korean ginseng have non-organ specific cancer preventive effects against cancer. Further research for clarifying the mechanisms of prevention and clinical trials on Korean ginseng must be conducted with worldwide collaborations

• 아동학회지
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• 제19권1호
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• pp.193-209
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• 1998

The present study assessed children's perceptions of risk of sexual abuse before and after participation in a sexual abuse prevention program, and investigated the effects of the sexual abuse prevention program on the children's emotional response. The subjects for this study were 135 3rd and 145 6th graders, attending elementary school in Seoul. Instruments were the Sexual Abuse Situational Risk (Jacobs, Hashima, & Kenning, 1995) and the Children's Emotional Response Questionnaire (Garbarino, 1987). The results of this study were that (1) children's perceptions of the risk of sexual abuse by a stranger decreased, relative to those by familiar persons which increased after the program. Especially, 6th graders had higher perceptions of the likelihood of abuse by familiar persons than 3rd graders. Girls had higher perceptions of risk than boys. (2) Children perceived adults as more dangerous than adolescents both before-and after-program. (3) Children's perceptions of the risk of sexual abuse in public settings decreased, relative to perceptions of risk in private settings which increased after the program. Girls had higher perceptions of the liklihood of abuse in private settings than boys; no significant difference was found by grade. (4) Children's emotional response did not reveal a significant change between pretest and posttests.