• 운동영양학회지
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• 제23권2호
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• pp.1-6
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• 2019

[Purpose] Strenuous exercise often induces skeletal muscle damage, which results in impaired performance. Sphingolipid metabolism contributes to various cellular processes, including apoptosis, stress response, and inflammation. However, the relationship between exercise-induced muscle damage and ceramide (a key component of sphingolipid metabolism), is rarely studied. The present study aimed to explore the regulatory role of sphingolipid metabolism in exercise-induced muscle damage. [Methods] Mice were subjected to strenuous exercise by treadmill running with gradual increase in intensity. The blood and gastrocnemius muscles (white and red portion) were collected immediately after and 24 h post exercise. For 3 days, imipramine was intraperitoneally injected 1 h prior to treadmill running. [Results] Interleukin 6 (IL-6) and serum creatine kinase (CK) levels were enhanced immediately after and 24 h post exercise (relative to those of resting), respectively. Acidic sphingomyelinase (A-SMase) protein expression in gastrocnemius muscles was significantly augmented by exercise, unlike, serine palmitoyltransferase-1 (SPT-1) and neutral sphingomyelinase (N-SMase) expressions. Furthermore, imipramine (a selective A-SMase inhibitor) treatment reduced the exercise-induced CK and IL-6 elevations, along with a decrease in cleaved caspase-3 (Cas-3) of gastrocnemius muscles. [Conclusion] We found the crucial role of A-SMase in exercise-induced muscle damage.

• 한국환경생태학회지
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• 제23권2호
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• pp.220-232
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• 2009

참나무시들음병 발생지역의 임분구조 특성 파악을 통한 피해해석을 목적으로, 전라남도와 제주도를 제외한 전국 7개도 18개 참나무시들음병 발생지역을 대상으로 식생조사를 실시하였고(Group A), 아울러 참나무시들음병의 매개충인 광릉긴나무좀(Platypus koryoensis)에 의한 피해 모니터링을 목적으로 설치된 경기도와 강원도 내 5개 고정조사지에도 식생조사를 실시하였다(Group B). 그 결과 전국 18개 지역(Group A) 가운데 17개 지역에서 참나무속(Quercus spp.) 수종들의 우점도가 가장 높게 나타났으며, 참나무시들음병 피해 모니터링을 목적으로 설치한 5개 고정조사지(Group B)에서는 참나무시들음병 피해 정도를 나타내는 지표 가운데 하나인 천공률(Relative Density of Entrance Holes)과 조사지 내 참나무속 수종들의 상대밀도 간에 통계적으로 매우 유의한 상관관계($R^2=0.89$, p<0.05)가 인정되어, 임분구조상 참나무속 수종의 우점도는 참나무 시들음병의 발생과 관련성이 높은 것으로 판단되었다.

• Tribology and Lubricants
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• 제22권2호
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• pp.59-65
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• 2006

In hard disk drives as the head to disk spacing continues to decrease to facilitate recording densities, slider disk interactions have become much more severe due to direct contact of head and disk surfaces in both start/stop and flying cases. The slider disk interaction in CSS (contact-start-stop) mode is an important source of particle generation and tribocharge build-up. The tribocharge build-up in the slider disk interface can cause ESD (electrostatic discharge) damage. In turn, ESD can cause severe melting damage to MR or GMR heads. The spindle speed of typical hard disk drives has increased in recent years from 5400 rpm to 15000 rpm and even higher speeds are anticipated in the near future. And the increasing disk velocity leads to increasing disk acceleration and this might affect the tribocharging phenomena of the slider/disk interface. We investigated the tribocurrent/voltage build-up generated in HDD, operating at increasing disk accelerations. In addition, we examined the effects with relative humidity conditions and rest time. We found that the tribocurrent/voltage was generated during pico-slider/disk interaction and its level was about $3\sim16pA$ and $0.1\sim0.3V$, respectively. Tribocurrent/voltage build-up was reduced with increasing disk acceleration. Higher humidity conditions $(75\sim80%)$ produced lower levels tribovoltage/current. Therefore, a higher tribocharge is expected at a lower disk acceleration and lower relative humidity condition. Rest time affected the charge build-up at the slider-disk interface. The degree of tribocharge build-up increased with increasing rest time.

• 한국환경복원기술학회지
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• 제18권6호
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• pp.97-110
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• 2015

This study aimed to classify damaged lands, to find what are the damage factors affecting the studied area, and to present a prescription in order to provide some benefit for the restoration of Regional Ecological Network at Chungnam province. Finally we classified damaged lands from 1st to 4th damaged lands according to relative intensity of damage. The main damage factors for the First Damage Lands were humus horizon, soil hardness and plant species richness. In the Second Damage Lands, those were soil hardness, plant species richness, number of plants and dominant plant species. In the Third Damage Lands, those were humus horizon, soil hardness, plant species richness, number of plants and dominant plant species. In the Fourth Damage Lands, those were humus horizon, organic matter, soil hardness, EC, T-N content, plant species richness, number of plants and dominant plant species. In every cases, the damage of soil and vegetation was originated due to development carried out by human being. The changes in soil condition were not big enough for it to affect plant growth, however, degradation of vegetation was still severe.

• 대한조선학회논문집
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• 제47권6호
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• pp.813-820
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• 2010

The spread mooring system for FPSO is developed to explore deep sea area, in which swell is dominant. It is known that the tension response of mooring lines in this sea area shows bimodal spectrum. Assuming normal distribution of tension profile and Rayleigh distribution of tension amplitude, the power spectral density function (PSD) of the mooring tension under the bimodal stationary random process is applied for the calculation of spectrum fatigue. Three popular methods, which are simple summation method, combined spectrum method and Jioa-Moan method, are used to combine fatigue damages from bimodal spectrum characteristics. Each damage value is compared with damage using Rainflow Cycle Counting (RCC) method which is believed to be close to exact solution. Vanmarcke' parameter and RMS(Root Mean Square) ratio are employed to assess relative damage variations between from RCC method and from three combination methods. Finally the most reliable fatigue damage combining method for spread mooring system is suggested.

• 한국농공학회:학술대회논문집
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• 한국농공학회 1999년도 Proceedings of the 1999 Annual Conference The Korean Society of Agricutural Engineers
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• pp.294-300
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• 1999

After researching the physical properties of the concrete included Rice Husk Ash(RHA concrete) and workability of fresh concrete admixed RHA, we have tested durability of RHA-concrete against freeaing and thawing in the winter using rapid freezing and thawing test method(KS F 2456) . There aretwo hypotheses to explain the failure mechanism of a freezing and thawing action. First, the hydraulic pressure in the pores of freezing concrete make an internal stress of concrete structures outbreaking micro crack in the face of concrete, Second, Frost action causing damage to cement paste repeatedly come from soil frost action, freezing water in the capillaries. Initial Relative Dynamic Modulus of Elasticity (DME) was biggest in cae of unit binder weight 600kgf/㎥ and relative dynamic modulus of elasticity increased until 300cycles. In general , initial relative DME was proportional to unit binder weight . Relative DME was decreased in proportion to unit binder weight in the case of 300, 400, 500kgf/㎥ , but relative DME fo the others remained more than 90% until 300 cycles. It was not good effect of intermixed RHA to concrete in case of below unit binder weight 300kgf/㎥ and the resistance of freezing and thawing was not good either.

• 한국구조물진단유지관리공학회 논문집
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• 제26권4호
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• pp.30-39
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• 2022

원자력발전소 주요기기의 건전성 유지는 구조물의 안전성과 관련하여 매우 중요한 문제로 인식되고 있으며 배관시스템의 건전성은 원자력발전소의 안전과 관련된 매우 중요한 문제이다. 지진하중으로 인한 배관시스템의 실제 파괴모드는 피로균열에 의한 누수이며 구조적인 손상 메커니즘은 소성변형을 발생할 수 있는 큰 상대변위로 인한 저주기 피로이다. 이 연구에서는 원자력발전소의 배관시스템에서 3인치의 강재 직관과 강재 배관 Tee로 구성된 시험체에 대하여 다양한 크기의 일정한 진폭에 대하여 면내반복가력실험을 수행하였다. 지진하중으로 인한 배관시스템에서 발생하는 상대변위를 고려하기 위하여 하중진폭을 증가시켰으며, 강재 배관 Tee의 한계상태인 피로균열에 의한 누수가 발생할 때까지 수행하였다. 힘과 변위의 관계에 대하여 손상모델에 기반을 둔 손상지수를 이용하여 한계상태를 표현하였다. 그 결과 손상지수를 이용하여 강재 배관 Tee의 한계상태를 정량적으로 표현할 수 있음을 확인할 수 있었다.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2001년도 가을 학술발표회 논문집
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• pp.1199-1202
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• 2001

The objective of this study is to examine the effect of frost damage immediately after placement on compressive strength of concrete. Obviously frost damage produced under low curing temperature at early ages causes the loss of compressive strength of concrete. In order to find the degrees of the loss of compressive strength, compressive strength tests was peformed at 7 and 28-day ages on concrete specimen with various curing temperature history. The results from the tests showed that the loss of compressive strength relative to concrete cured under isothermal temperature at $20^{\circ}C$ was generally from 20 to 50% for 7-day ages and below 20% for 28 day ages. Considering the serious loss of compressive strength over 50% for some cases, careful attention may be needed to placing of concrete under low atmospheric temperature.

• Structural Engineering and Mechanics
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• 제44권5호
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• pp.585-600
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• 2012

This paper presents a Modified Tikhonov Regularization (MTR) method in model updating for damage identification with model errors and measurement noise influences consideration. The identification equation based on sensitivity approach from the dynamic responses is ill-conditioned and is usually solved with regularization method. When the structural system contains model errors and measurement noise, the identified results from Tikhonov Regularization (TR) method often diverge after several iterations. In the MTR method, new side conditions with limits on the identification of physical parameters allow for the presence of model errors and ensure the physical meanings of the identified parameters. Chebyshev polynomial is applied to approximate the acceleration response for moderation of measurement noise. The identified physical parameter can converge to a relative correct direction. A three-dimensional unsymmetrical frame structure with different scenarios is studied to illustrate the proposed method. Results revealed show that the proposed method has superior performance than TR Method when there are both model errors and measurement noise in the structure system.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2004년도 춘계학술대회 논문집
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• pp.1142-1147
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• 2004

In this study, two damage detection techniques are applied to the railway tunnel liner based on the static deformation data. Models based on uniform reduction of stiffness and smeared crack concept are both employed, and the efficiency and relative advantage are compared with each other. Numerical analyses are performed on the idealized tunnel structure and the effect of white noise, common in most measurement data, is also investigated to better understand the suitability of the proposed models. As a result, model 1 based on uniform stiffness reduction method is shown to be relatively insensitive to the noise, while model 2 with the smeared crack concept is proven to be easily applied to the field situation since the effect of stiffness reduction is rather small. Finally, real deformation data of a rail tunnel in which health monitoring system is in operation are introduced to find the possible damage and it is shown that the prediction shows quite satisfactory result.