• 제목/요약/키워드: Relative damage

검색결과 562건 처리시간 0.024초

Chronological Switch from Translesion Synthesis to Homology-Dependent Gap Repair In Vivo

  • Fujii, Shingo;Isogawa, Asako;Fuchs, Robert P.
    • Toxicological Research
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    • 제34권4호
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    • pp.297-302
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    • 2018
  • Cells are constantly exposed to endogenous and exogenous chemical and physical agents that damage their genome by forming DNA lesions. These lesions interfere with the normal functions of DNA such as transcription and replication, and need to be either repaired or tolerated. DNA lesions are accurately removed via various repair pathways. In contrast, tolerance mechanisms do not remove lesions but only allow replication to proceed despite the presence of unrepaired lesions. Cells possess two major tolerance strategies, namely translesion synthesis (TLS), which is an error-prone strategy and an accurate strategy based on homologous recombination (homology-dependent gap repair [HDGR]). Thus, the mutation frequency reflects the relative extent to which the two tolerance pathways operate in vivo. In the present paper, we review the present understanding of the mechanisms of TLS and HDGR and propose a novel and comprehensive view of the way both strategies interact and are regulated in vivo.

가축 소음피해특성 분석에 관한 사례연구 -환경분쟁조정사례를 중심으로- (A case study on the analysis of the noise damage characterization of livestock)

  • 백용진;최재성;김경진;배동명
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2002년도 추계학술대회논문집
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    • pp.755-761
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    • 2002
  • Recently, the noise damage cases of livestock are increasing rapidly. The cases related to the livestock damage were occupied 20% of noise and vibration dispute intervention cases from 1991 to 2001. Of this results, 34% (16/38) are relative to pig, 27%(13/30) to domestic fowl and 20%(9/38) to cattle. The results of regression analysis of between the approval of damage rates (ADR) and a noise level by livestock have been derived that pigs was highly sensitive. In case of cattle, the regression model to apply the ADR according to the appraised noise level was made, but it needs to be complemented later.

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가축 소음피해특성 분석에 관한 사례연구 -환경분쟁조정사례를 중심으로- (A case study on the analysis of the noise damage characterization of livestock)

  • Baek, Yong-Jin;Park, Jae-Sung;Kim, Kyung-Jin;Bae, Dong-Myoung
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2002년도 추계학술대회논문초록집
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    • pp.375.1-375
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    • 2002
  • Recently, the noise damage cases of livestock are increasing rapidly. The cases related to the livestock damage were occupied 20% of noise and vibration dispute intervention cases from 1991 to 2001. Of this results, 34%(16/38) are relative to Pig, 27%(13/38) to domestic fowl and 20%(9/38) to cattle. The results of regression analysis of between the approval of damage rates (ADR) and a noise level by livestock have been derived that pigs was highly sensitive. (omitted)

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Modal flexibility based damage detection for suspension bridge hangers: A numerical and experimental investigation

  • Meng, Fanhao;Yu, Jingjun;Alaluf, David;Mokrani, Bilal;Preumont, Andre
    • Smart Structures and Systems
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    • 제23권1호
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    • pp.15-29
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    • 2019
  • This paper addresses the problem of damage detection in suspension bridge hangers, with an emphasis on the modal flexibility method. It aims at evaluating the capability and the accuracy of the modal flexibility method to detect and locate single and multiple damages in suspension bridge hangers, with different level of severity and various locations. The study is conducted numerically and experimentally on a laboratory suspension bridge mock-up. First, the covariance-driven stochastic subspace identification is used to extract the modal parameters of the bridge from experimental data, using only output measurements data from ambient vibration. Then, the method is demonstrated for several damage scenarios and compared against other classical methods, such as: Coordinate Modal Assurance Criterion (COMAC), Enhanced Coordinate Modal Assurance Criterion (ECOMAC), Mode Shape Curvature (MSC) and Modal Strain Energy (MSE). The paper demonstrates the relative merits and shortcomings of these methods which play a significant role in the damage detection ofsuspension bridges.

Damage detection for a beam under transient excitation via three different algorithms

  • Zhao, Ying;Noori, Mohammad;Altabey, Wael A.
    • Structural Engineering and Mechanics
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    • 제64권6권
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    • pp.803-817
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    • 2017
  • Structural health monitoring has increasingly been a focus within the civil engineering research community over the last few decades. With increasing application of sensor networks in large structures and infrastructure systems, effective use and development of robust algorithms to analyze large volumes of data and to extract the desired features has become a challenging problem. In this paper, we grasp some precautions and key points of the signal processing approach, wavelet, establish a relative reliable framework, and analyze three problems that require attention when applying wavelet based damage detection approach. The cases studies how to use optimal scales for extracting mode shapes and modal curvatures in a reinforced concrete beam and how to effectively identify damages using maximum curves of wavelet coefficient differences. Moreover, how to make a recognition based on the wavelet multi-resolution analysis, wavelet packet energy, and fuzzy sets is a meaningful topic that has been addressed in this work. The relative systematic work that compasses algorithms, structures and evaluation paves a way to a framework regarding effective structural health monitoring, orientation, decision and action.

Steel frame fragility curve evaluation under the impact of two various category of earthquakes

  • Wang, Feipeng;Miao, Jie;Fang, Zhichun;Wu, Siqi;Li, Xulong;Momeni, Younes
    • Earthquakes and Structures
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    • 제22권1호
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    • pp.15-23
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    • 2022
  • One of the key tools in assessing the seismic vulnerability of the structures is the use of fragile functions, which is the possibility of damage from a particular damage surface for several levels of risk from the seismic movements of the earth. The aim of this study is to investigate the effect of two categories of earthquake events on the fragile curve (FRC) of the steel construction system. In this study, the relative lateral displacement of the structures is considered as a damage criterion. The limits set for modifying the relative lateral position in the HAZUS instruction are used to determine the failure modes, which include: slight, moderate, extensive and complete. The results show, as time strong-motion increases, the probability of exceeding (PoE) increases (for Peak ground acceleration (PGA) less than 0.5). The increase in seismic demand increases the probability of exceeding. In other words, it increases the probability of exceeding, if the maximum earthquake acceleration increases. Also, 7-storey model in extensive mode has 20 and 26.5% PoE larger than 5- and 3-storey models, respectively.

통계적 기법을 이용한 국지성집중호우의 이동경로 분석 (Rainstorm Tracking Using Statistical Analysis Method)

  • 김수영;남우성;허준행
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2005년도 학술발표회 논문집
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    • pp.194-198
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    • 2005
  • Although the rainstorm causes local damage on large scale, it is difficult to predict the movement of the rainstorm exactly. In order to reduce the rainstorm damage of the rainstorm, it is necessary to analyze the path of the rainstorm using various statistical methods. In addition, efficient time interval of rainfall observation for the analysis of the rainstorm movement can be derived by applying various statistical methods to rainfall data. In this study, the rainstorm tracking using statistical method is performed for various types of rainfall data. For the tracking of the rainstorm, the methods of temporal distribution, inclined Plane equations, and cross correlation were applied for various types of data including electromagnetic rainfall gauge data and AWS data. The speed and direction of each method were compared with those of real rainfall movement. In addition, the effective time interval of rainfall observation for the analysis of the rainstorm movement was also investigated for the selected time intervals 10, 20, 30, 40, 50, and 60 minutes. As a result, the absolute relative errors of the method of inclined plane equations are smaller than those of other methods in case of electromagnetic rainfall gauges data. The absolute relative errors of the method of cross correlation are smaller than those of other methods in case of AWS data. The absolute relative errors of 30 minutes or less than 30 minutes are smaller than those of other time intervals.

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염해 및 동결융해의 복합열화 작용에 의한 부식촉진시험에 관한 연구 (A Study on Accelerated Corrosion Test by Combined Deteriorating Action of Salt Damage and Freeze-Thaw)

  • 박상순;소병탁
    • Corrosion Science and Technology
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    • 제15권1호
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    • pp.18-27
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    • 2016
  • In this study, the accelerated corrosion test by combined deteriorating action of salt damage and freeze-thaw was investigated. freeze-thaw cycle is one method for corrosion testing; corrosion initiation time was measured in four types of concrete samples, i.e., two samples mixed with fly ash (FA) and blast furnace slag (BS), and the other two samples having two water/cement ratio (W/C = 0.6, 0.35) without admixture (OPC60 and OPC35). The corrosion of rebar embedded in concrete occurred most quickly at the $30^{th}$ freeze-thaw cycle. Moreover, a corrosion monitoring method with a half-cell potential measurement and relative dynamic elastic modulus derived from resonant frequency measures was conducted simultaneously. The results indicated that the corrosion of rebar occurred when the relative dynamic elastic modulus was less than 60%. Therefore, dynamic elastic modulus can be used to detect corrosion of steel bar. The results of the accelerated corrosion test exhibited significant difference according to corrosion periods combined with each test condition. Consequently, the OPC60 showed the lowest corrosion resistance among the samples.

Improvement of MFL sensing-based damage detection and quantification for steel bar NDE

  • Kim, Ju-Won;Park, Minsu;Kim, Junkyeong;Park, Seunghee
    • Smart Structures and Systems
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    • 제22권2호
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    • pp.239-247
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    • 2018
  • A magnetic flux leakage (MFL) method was applied to detect and quantify defects in a steel bar. A multi-channel MFL sensor head was fabricated using Hall sensors and magnetization yokes with permanent magnets. The MFL sensor head scanned a damaged specimen with five levels of defects to measure the magnetic flux density. A series of signal processing procedures, including an enveloping process based on the Hilbert transform, was performed to clarify the flux leakage signal. The objective damage detection of the enveloped signals was then analyzed by comparing them to a threshold value. To quantitatively analyze the MFL signal according to the damage level, five kinds of damage indices based on the relationship between the enveloped MFL signal and the threshold value were applied. Using the proposed damage indices and the general damage index for the MFL method, the detected MFL signals were quantified and analyzed relative to the magnitude of the damage increase.

전자지불거래에서 상대위치와 연동한 도용 위험성 산출방법 (Relative Location based Risk Calculation to Prevent Identity Theft in Electronic Payment Systems)

  • 서효중;황호영
    • 문화기술의 융합
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    • 제6권1호
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    • pp.455-461
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    • 2020
  • 인터넷뱅킹과 전자지불거래는 인터넷을 이용한 개인의 경제적 행동 중 매우 중요하고 민감한 내용이다. 핀테크와 관련한 해킹 및 도용이 발생할 경우 사용자의 직접적 금전피해로 이어지므로 이러한 사고를 막기 위해 적극적 방법들이 사용되고 있으며, 특히 이상금융거래탐지시스템(FDS)은 전자지불거래시의 위험률을 도출하고 도용을 탐지한다. 전자지불과 같은 상거래의 경우 스마트폰의 상태, 물품과 매장의 종류, 구매자의 위치 등 프로파일링에 따라 위험률을 도출하고 있다. 본 논문에서는 이러한 전자지불거래에 있어서 기존의 물리적 위치에 의한 것이 아닌 사용자의 상대적 위치에 의한 위험률 도출 방법을 제안하고자 한다. GPS 주소나 IP 경로주소와 같은 정보를 활용하는 절대위치와 달리, 상대위치는 무선랜 환경을 감지하여 무선 AP의 ID 및 MAC 주소를 이용한 각 개인의 상대위치 정보를 활용하며, 각 개인의 특성을 감안한 상대적 디지털 환경을 누적 감지하는 방법을 통해 전자지불거래를 검증하여 위험률을 도출하는 방법이다. 절대위치의 경우 국적이나 주소 등의 정적 데이터 수집을 통하여 아이디를 도용할 수 있는 약점이 있는 반면, 상대위치의 경우 연관된 디지털 정보의 모사가 쉽지 않아 이로 인한 보안상의 이득을 얻게 된다.