• 대한물리의학회지
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• 제10권1호
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• pp.53-61
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• 2015

PURPOSE: This study examined the effect of the combined exercise program on physical fitness and related hormone in elderly women. METHODS: The subjects included 40 elderly women who reside at B city. Upon thire agreements, the subjects were divided into either an experimental group and the control group. there 20 subjects in each. The combined exercise program was conducted during the 8 weeks, and the experimental group was underwent its associated program 5 times a week. there wear 2 subjects from each group that were excluded. The physical fitness wear measured and the related hormone(growth hormone, DHEA) were taken with blood serum density. RESULTS: After 8 weeks for intervention, there were statistically significant differences between in physical fitness and growth hormone, DHEA in experimental group(p<.05). however, this difference was not significantly different in the control group. Futher, there wear statistically significant difference between two group of all item(p<.05). CONCLUSION: The findings of this study show that combined exercise program helps the physical fitness and increase of growth hormone, DHEA in elderly women. In conclusion, the regular combined exercise program for 8 weeks is effective for increase physical fitness and related hormone in elderly women, and positive influence upon, thereby being thought to be able to lower risk in aging and weakness.

• Journal of Plant Biotechnology
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• 제47권3호
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• pp.194-202
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• 2020

The sweetpotatoes (Ipomoea batatas) generate adventitious roots (ARs) from cut stems that develop into storage roots and make for an important means of propagation. However, few studies have investigated the hormones involved in AR development in sweetpotato. In this study, the expression patterns of hormone-related genes involved in AR formation were identified using the transcriptome data. RNA-seq data from stems grown for 0 and 3 days after cutting were analyzed. In addition, hormone-related genes were identified among differentially expressed genes (DEGs) and filtered genes, and cluster analysis was used to characterize expression patterns by function. Most hormone-related regulated genes expressed 3 days after growing the cut stems were abscisic acid (ABA)-related genes, followed by ethylene- and auxin-related genes. For ABA, the biosynthesis genes (including genes annotated to NINE-CIS-EPOXYCAROTENOID DIOXYGENASE 3 (NCED3)) and signal transduction and perception genes (including genes annotated to PROTEIN PHOSPHATASE 2Cs (PP2Cs)) tended to decrease. Expression patterns of auxin- and ethylene-related genes differed by function. These results suggest that ABA, auxin, and ethylene genes are involved in AR formation and that they may be regulated in a hormone function-dependent manner. These results contribute to the identification of hormone functions during AR formation and may contribute to understanding the mechanism of AR formation in the sweetpotato.

• 대한한방소아과학회지
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• 제15권1호
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• pp.105-115
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• 2001

The relation of endocrine in the western medicine and zangfu-organ functions in Korean medicine, related to growth disturbance, was studied and derived the following results. 1. The hormone most related to growth disturbance is, directly secreted from the anterior pituitary or is stimulated and secreted in the target grands, growth hormone, thyroid, adrenocortical hormone, gonadial hormone and is insulin secreted from $\beta$ cell of langerhans' slands of pancreas. 2. the pituitary has the most close relation with the kidney in the five zang-organ. Because the kidney is innate origin(先天之本) and promotes qi and blood(生化氣血), stores the essence of life(藏精), dominates the bones(主骨) and promotes the marrow(生骨髓). Especially it is connected with brain(通於腦). 3. In the children growth, the endocrine action in the pituitary has the most close relation with the kidney, As in the reports of the brain and spinal cord, bone, store essence of life, sexual maturation and decline(kidney-qi, sexual functions of both sexes(天癸)) etc, and cause of cretinism, dwarf in the main subject. 4. Somatomedin is the most important factor of the growth factors, IGF in another word. The unification of IGF and secretion is controlled firstly according to growth hormone, however is very closely related to the nutrition status in the non-hormonic causes. Also, it is affected very much by the insulin. 5. Insulin is one of the important hormone related to the growth and is secreted from the pancreas. Pancreas belongs to the functional system of spleen in oriental medicine, thus the growth disturbance, occurred due to error in insulin secretion and nutrition(in another words, the lack of postnatal essential substance from food-stuff(水穀精氣)), is closely related to the spleen. 6. From the results driven above, the hormone action of endocrine and problem in secretion, related to the growth disturbance, must be focused on the differentiation of symptoms and signs of the kidney and the spleen in oriental medicine.

• 한국동물학회:학술대회논문집
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• 한국동물학회 1996년도 한국생물과학협회 국제학술대회
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• pp.171.2-171
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• 1996

No Abstract, See Full Text

• Fisheries and Aquatic Sciences
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• 제6권3호
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• pp.116-124
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• 2003

Isolation and cloning of seven-band grouper (Epinephelus septemfasciatus) growth hormone cDNA from pituitary gland revealed an open reading frame of 612 bp coding for a pre-growth hormone of 204 amino acids with a 17 amino acid putative signal peptide. Deduced amino acid sequence showed that there was one possible N-glycosylation site at $Asn^{l84}$ and four cysteine residues $(Cys^{52},\;Cys^{160},\;Cys^{177},\;Cys^{185})$ on t e same positions as in some other species where they were involved in the stabilization of the tertiary structure. The seven-band grouper growth hormone (sbgGH) presented a $99.5\%$ amino acid sequence identity with the growth hormone of Epinephelus coioides and contained the conserved hormone domain region. Comparison of growth hormone sequences from evolutionarily diverse species revealed 25 amino acid residues conserved in jawless fishes to modern mammals. It also revealed an evolutionary trend to retain the same polypeptide sequence even in the distantly related animals while allowing alterations to occur in polypeptides of the closely related species. In order to create a recombinant system to produce high levels of the growth hormone, it was expressed in Escherichia coli (BL21) cells. The gel analysis revealed theoretically expected molecular weights for both mature and pre-sbgGHs.

• Clinical and Experimental Reproductive Medicine
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• 제41권2호
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• pp.86-91
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• 2014

Objective: The aim of the present study was to investigate the relationship between ovarian follicle count and volume on ultrasonography and serum hormone levels including the levels of the anti-$M\ddot{u}llerian$ hormone (AMH) and gonadotropin in women with the polycystic ovary syndrome (PCOS). Methods: A total of 118 Korean women aged 18-35 years who were newly diagnosed with PCOS at a university hospital were included in this study. Serum LH, FSH, and AMH levels were measured in the early follicular phase, and the total antral follicle count (TFC) and the total ovarian volume (TOV) were assessed by ultrasonography. The correlations between serum hormonal parameters and ultrasonography characteristics in women with PCOS were evaluated using Pearson's correlation coefficients and a linear regression analysis. Results: Serum AMH levels were significantly correlated with serum LH levels and LH/FSH ratios, and TFC and TOV were significantly correlated with each other on ultrasonography. Serum AMH and LH levels and the LH/FSH ratio were significantly correlated with TFC. Statistically significant correlations between TOV and the LH level (r=0.208, p=0.024) and the LH/FSH ratio (r=0.237, p=0.010) were observed. However, the serum AMH level was not significantly correlated with the ovarian volume, and this result did not change after adjusting for age and body mass index. Conclusion: Serum AMH is not related to the ovarian volume in women with PCOS. My results suggest that serum LH level and the LH/FSH ratio may be more useful than the serum AMH level for representing the status of the ovarian volume in women with PCOS.

• 한국산학기술학회논문지
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• 제20권10호
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• pp.62-67
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• 2019

본 연구는 rotifer Brachionus rotundiformis의 유성생식을 유도하기 위해 효과적인 매개물질로 몇 가지 성 steroid hormone (serotonin, progesterone 및 ${\beta}$-estradiol)을 선정하여 농도별(Low, 30 mg/L 및 High, 300 mg/L)로 내구란 생산효과를 6일 동안 배양하면서 조사하였다. 배양 3일째 ${\beta}$-estradiol ($E_2$) 처리구가 다른 실험구에 비해 유성생식률이 20.6%로 가장 높게 나타났다. 배양 6일째 내구란 생산수(106 개)도 동일한 결과를 보였으며 다음으로는 serotonin이 높게 나타났다. 더하여, 위 스테로이드 호르몬이 몇 가지 유성생식관련 유전자의 발현에 미치는 영향에 대해 조사한 결과, NrbP, SRY, Cyclin 및 MrpmB 유전자가 처리한 모든 hormone에 대해 up-regulation되는 경향을 보였다. 결과를 종합해보면, B. rotundiformis의 내구란 생산에 가장 효과적인 steroid hormone은 ${\beta}$-estradiol인 것으로 판단되며 유성생식 관련 유전자로 NrbP, SRY, MrpmrB 및 Cyclin을 제안할 수 있다. 차후 효과적인 내구란 생산을 위한 $E_2$의 최적 처리농도규명에 관한 추가 연구가 필요할 것으로 판단된다.

• 한방비만학회지
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• 제1권1호
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• pp.1-11
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• 2001

Obesity is a metabolic disease associated with multiple hormonal abnormalities. Therefore, obesity management aims at balancing these endocrine malfunctions nowadays. Although many studies proved interactions of hormones related with obesity, there are still lots of controversies. Most of these malfunctions are more pronounced in central, visceral obesity than in peripheral obesity. Recently, it is revealed that a central lesion of endocrine malfunction in human visceral obesity is probably related with a hypersensitivity of hypothalamopituitary-adrenal(HPA) axis. Probably associated with this axis, Insulin and cortisol promote lipid accumulation by expressing lipoprotein lipase activity, while sex hormones and growth hormone exert the opposite effects. Also reviewed was thyroid hormone which is closely related with thermogenesis. Serotonin is prescribed as antidepressant and it is applied to some eating disorders. Recently, leptin made in fat deposit also took attentions in terms of regulator of appetite and messenger of sex signal.

• Journal of mucopolysaccharidosis and rare diseases
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• 제2권2호
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• pp.38-40
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• 2016

Prader-Willi syndrome (PWS) is a rare genetic disorder often caused by a deletion of the chromosome 15q11-q13 region inherited from the father or by maternal disomy 15. Growth hormone deficiency with short stature, hypogonadism, cognitive and behavioral problems, analgesia, decreased gastric motility and decreased ability to vomit with hyperphagia are common in PWS leading to severe obesity in early childhood, if not controlled. The goal of this study is to investigate the effects of recombinant human GH (rhGH, henceforth designated GH) on the gene expression related to cognitive function in the brain of PWS mouse model (Snord116del). GH restored the mRNA expression level of several genes in the cerebellum. These data suggest the effect of GH on the expression of cognitive function related genes in cerebellum may provide a mechanism for the GH-induced brain function in PWS patients.

• 한국융합학회논문지
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• 제9권10호
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• pp.449-456
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• 2018

본 연구는 비만 중년여성을 대상으로 8주간 자전거 운동을 통한 염증관련인자와 성장호르몬의 변화를 분석함으로써 자전거 운동의 효과를 규명하고 효율적인 운동을 위한 과학적 근거를 제시하는데 그 목적이 있다. 15명의 비만 중년 여성들은 자전거 운동군과 통제군으로 구분하여 8주간 주당 3회 60분간 자전거를 이용한 유산소 운동 프로그램을 실시하였다. 측정변인으로는 염증관련인자와 성장호르몬의 변화를 분석하였으며 통계처리는 이원 반복측정 분산분석(two-way ANOVA with repeated measure)을 실시하였다. 분석 결과 염증관련인자는에서 $TNF-{\alpha}$ 및 IL-6는 운동군에서 유의한 감소를 보였으며 통제군에서 증가하였다. 성장호르몬은 운동군에서 증가하였으나 유의한 차이가 나타나지 않았으며 통제군에서 감소하였다. 이와 같은 결과는 본 연구에서 실시한 자전거 운동이 비만 중년여성들의 심혈관계 및 만성질환을 예방 할 수 있는 운동 프로그램이라고 사료된다.