• 지역사회간호학회지
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• 제23권4호
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• pp.427-437
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• 2012

Purpose: In order to lower the infection rate and the reinfection rate of Clonorchiasis in high-risk areas, we performed and analyzed a case management on people with chlonorchisis. Methods: The data was collected from April 2010 to March 2011. A community health practitioner was selected as a case manager based on our training program. The intervention group had 58 participants with three months of case management and the control group had 144 participants handled with traditional methods. Results: the pre and post-test in the intervention group and the control group showed us improved knowledge of Clonorchiasis, attitudes and behavior toward eating freshwater fish. The results of post-test between the intervention group and the control group showed statistically significant differences in all categories, except a hand-washing category. However, one year after a case management, there was no significant difference in the failure rate of treatment. Conclusion: The case management was effective for people infected with Clornorchiasis near riverside areas; however, in order to lower the rates of reinfection and treatment failure, it is necessary to perform continuous monitoring and regular evaluations.

• 대한족부족관절학회지
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• 제17권3호
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• pp.209-214
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• 2013

Purpose: To evaluate correlation between the clinical results and causative bacteria in diabetic foot patients with lower extremity amputation. Materials and Methods: One hundred twenty nine patients(131 feet) of diabetic foot amputations were followed for more than one year. Wound cultures were done by deep tissue or bone debris at first visit to our clinics. Retrospective analysis was performed using chart review and interview with the patients. Depending on the culture result, level of amputation, reinfection, duration of treatment, death rate, patient satisfaction and admission dates were evaluated. Results: Microorganisms were confirmed in 114 cases. In the other 17 cases, there were no cultured microorganisms. In bacterial growth group, Methicillin-sensitive Staphylococcus aureus was the most common pathogen and accounted for 34 cases. As other common pathogens, there were Methicillin-resistant Staphylococcus aureus(24 cases) and mixed infection(14 cases). Mortality is no difference in each infected group. Mixed bacterial infected patients have higher reinfection, longer hospital day and duration of treatment, but there is no difference in patients satisfaction and pain at last follow up. Conclusion: The most common pathogen in diabetic foot patients with lower extremity amputation was Methicillin-sensitive Staphylococcus aureus, and mixed bacterial infected patients have higher reinfection rate, longer admission date and duration of treatment than other bacterial infected patients.

• Parasites, Hosts and Diseases
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• 제40권4호
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• pp.191-193
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• 2002

Oriental liver fluke (Clonorchis sinensis) infection was surveyed among residents of Hamyang-gun, Gyeongsangnam-do, Korea during the period of January 2001 to March 2002. Total 1,041 stool samples were collected from residents who visited Public Health Center and its branches in Hamyang-gun and examined using formalin-ether sedimentation method. The overall egg positive rate was 16%, male showing higher positive rate (21%) than female (10%). The age group of 30 to 50 years had the highest egg positive rate of C. sinensis from 20% to 22%. The positive examinees were treated with praziquantel and educated individually to prevent reinfection . Egg positive rate in this area was decreased when compared with results recorded in the past, however, still remained more than 10%. This study suggests that periodic examination, treatment as well as education of residents should be continued and systematized.

• 식물병연구
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• 제12권1호
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• pp.28-31
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• 2006

최근 감자 바이러스의 발생 양상은 과거에는 PLRV의 이병율이 높았으나 현재에는 PVY의 발생이 많아지고 있는 추세인데 이는 '대서'와 '추백' 같은 감수성 품종의 재배 면적의 증가와 바이러스 이병율이 높은 재배 환경에서의 채종 때문일 것이다. 특히 2기작 감자 포장에서의 당대 감염율을 보더라도 '대서'와 '추백'의 이병율이 높아 감수성 품종으로 '수미'와 '대지'는 이병율이 비교적 낮아 저항성으로 나타났다. 또한 2기작 감자 재배지대에서 PVY에 감수성인 '추백' 품종의 안전한 씨감자 생산을 위해서 주위에 일반감자 재배가 없는 격리가 양호한 환경에서의 채종과 그렇지 못한 환경에서의 채종을 비교하여 재감염 정도를 조사하였는데 조직 배양후 2세대 걸친 노지 재배에서 바이러스 이병율이 약 3배의 차이를 보여 씨감자 생산에서 채종 환경의 중요성을 입증한 결과로 판명되었다.

• Parasites, Hosts and Diseases
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• 제39권4호
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• pp.323-325
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• 2001

The egg Positive rate of Enterobius vermicularis and Clonorchis sinensis of school children in the rural area was studied in Hamyang-gun, Gyeongsangnam-do in Korea. Cellotape anal swab and formalin ether concentration methods were performed one time to 720 Primary school children. The total egg Positive rate of E. vermicularis was 12.6% in two schools (Baekjeon and Wiseong). In the Baekjeon and Wiseong primary school, the egg Positive rate of E. vermicularis was 4.6% and 13.4%, respectively Pinworm egg Positive rate was 17.6% in the lower grades (1st, 2nd and 3rd), and 7.7% in higher grades (4th, 5th and 6th). The total egg Positive rate of male and female was 12.6% and 12.7%, respectively. The egg Positive rate of C. sinensis of Baekjeon and Wiseong Primary school was 1.5% and 0.46%, respectively The total e99 Positive rate of C. sinesis was 0.56%. This survey showed that continuous education and chemotherapy is necessary to treat and prevent reinfection of E. vermicularis. In the case of C. sinensis, health education for school children is recommended to prevent potential infection of adolescents.

• Journal of Chest Surgery
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• 제51권1호
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• pp.15-21
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• 2018

Background: Prosthetic valve endocarditis (PVE) is a serious complication of cardiac valve replacement, and many patients with PVE require reoperation. The aim of this study was to review our institutional 20-year experience of surgical reoperative valve replacement in patients with PVE. Methods: A retrospective study was performed on 84 patients (mean age, $54.8{\pm}12.7years$; 51 males) who were diagnosed with PVE and underwent reoperative valve replacement from January 1995 to December 2016. Results: PVE was found in 1 valve in 61 cases (72.6%), and in 2 or more valves in 23 cases (27.4%). The median follow-up duration was 47.3 months (range, 0 to 250 months). Postoperative complications occurred in 39 patients (46.4%). Reinfection occurred in 6 cases, all within 1 year. The freedom from reinfection rate at 5 years was $91.0%{\pm}3.5%$. The overall survival rates at 5 and 10 years were $64.4%{\pm}5.8%$ and $54.3%{\pm}7.3%$, respectively. In stepwise multivariable Cox proportional hazard models, older age (hazard ratio [HR], 1.48; 95% confidence interval [CI], 1.05 to 2.10; p=0.027) and cardiopulmonary bypass (CPB) time (HR, 1.03; 95% CI, 1.00 to 1.01; p=0.033) emerged as independent risk factors for death. Conclusion: Older age and a longer CPB time were associated with an increased risk of overall mortality in PVE patients.

• 원예과학기술지
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• 제33권6호
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• pp.891-899
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• 2015

본 연구는 자생나리에 있어서 기내 인편삽의 계대배양이 lily symptomless virus(LSV) 제거에 미치는 영향과 구근 재배 조건이 LSV 재감염에 미치는 영향을 구명하여 LSV 무병주 대량 생산을 위한 기초자료를 제공하기 위하여 실시되었다. 식물재료로는 날개하늘나리(L. dauricum), 말나리(L. distichum), 참나리(L. lancifolium), 중나리(L. maximowitzii)등 자생나리 4종을 사용하였다. LSV에 감염된 식물체의 인편에서 소인경을 얻은 다음 이들 소인경을 5회 이상 계대배양을 했을 때 LSV가 완전히 제거되었다. 특히 날개하늘나리와 말나리에서는 1회 기내 인편삽으로도 LSV를 완전히 제거할 수 있었다. 그러나 기내배양을 통해 생산된 LSV 무병주라도 구근의 재배기간이 길수록, 봄 정식구보다 가을 정식구에서, 소식구보다 밀식구에서, 해안지역보다는 내륙 지역에서 재감염률이 높았다. 그리고 재감염률은 중나리가 날개하늘나리와 참나리보다 높았다. LSV 감염주는 무병주에 비해 엽록소 함량이 낮았다. 따라서 자생나리 구근의 수회 계대배양을 통해 LSV를 제거할 수 있으며, 구근 생산과정에서 낮은 재식밀도, 봄 정식, 해안지역 정식 등 재배적 방제를 통해 LSV 재감염을 억제할 수 있을 것이다.

• Parasites, Hosts and Diseases
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• 제23권2호
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• pp.241-246
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• 1985

우리나라 8개 농촌지역의 회충 감염율, 감염 량 및 기초산란율(basic reproductive rate)등 역학적 변수의 상관관계를 관찰함으로써 우리나라 회충감염 실태를 분석하였다. 이들 감염율, 감염량 등은 대변검사는 물론 pyrantel pamoate투여후 충체 회수결과에 의해 측정하였으며 그 결과는 다음과 같다. 1. 각 조사지역의 충체양성률(감염율)은 16.5~79.5%의 범위에 있었고 이것은 대변검사에 의한 충란양성률 3.3~66.7%보다 9~18%가 높은 수치이었다. 조사대상 주민의 평균 회충 감염량은 지역에 따라 0.21에서 8.44로 나타났고 개인별 감염량 분포는 'k'치가 0.38~0.54인 부이항분포(negative binomial distribution)를 보였다. 2. 이 조사에서 나타난 충체양성률은 Anderson과 May의 수식 $p=1-(1+M^{*}/k)^{-k}$ (p : 충체양성률, $M^*$ : 평형상태의 평균 감염량)에 의해 구한 이론치와 거의 일치하여 우리나라 농촌지역의 회충감염률과 감염량의 상관관계는 이 수식에 의해 매우 정확히 표현됨을 알 수 있었다. 또 회충 암컷 1마리가 평생 산출하는 무수한 충란중 다음 숙주에 성공적으로 감염되고 성숙되는 암컷의 수를 표시하는 기초산란을(R)은 지역에 따라 1.03에서 2.11까지인 것으로 나타났다. 이상의 결과로 보아 'R'치가 1에 가까운 지역은 역학적으로 재감염의 breakpoin떼 도달하고 있는 것으로 판정되므로 회충 박멸이 매우 희망적이지만 전국적으로 'R'치가 1이하로 될 때까지 우리나라 회충관리사업은 계속되어야 할 것으로 생각된다.

• Journal of Oral Medicine and Pain
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• 제37권2호
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• pp.75-79
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• 2012

위염 및 위암 등의 발생과 관련되어 있는 Helicobacter pylori(H. pylori)는 구강의 치태와 타액에서 주로 발견이 된다. 유년시절 동안 주로 감염되는 것으로 알려져 있지만 감염경로는 불분명하다. 구강이 H. pylori의 두 번째 서식지로서 전염경로 및 위장내 H. pylori의 제균 후 재감염에 중요한 영향을 끼칠 수 있는지는 논쟁이 되고 있다. 따라서 본 저자는 문헌고찰을 통하여 구강 내에 존재하는 H. pylori에 관하여 알아보고자 하였다. 위장에 존재하는 H. pylori는 위인두반사나 구토에 의해 구강 내 발현될 수도 있으나, 구강과 위의 감염은 서로 관련성이 없는 것으로 보고되고 있다. 진단방법으로는 혈청학적검사, 요소호기검사, 중합효소연쇄반응(polymerase chain reaction: PCR)방법, Urease검사, 조직검사 등이 있으나, 타액과 치태에서는 nested PCR 방법이 주로 추천되어 진다. 구강 내 감염율은 다양하게 나타나며, 치과질환과의 연관성은 없는 것으로 사료된다. 그러나 치주질환 환자의 구강 내에서 발현율은 높게 나타나므로, 주의가 요구되며 향균 구강세척제의 사용이 권유된다. 결과적으로 구강 내 H. pylori는 정상세균총으로 사료되며, 향후 구강내 H. pylori에 관한 추가적인 많은 연구가 필요하리라 사료된다.

• Parasites, Hosts and Diseases
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• 제61권2호
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• pp.103-126
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• 2023

In the l950s, under the legacy of traditional agriculture, Ascaris lumbricoides, spread epidemically in the war-bitten society of Korea. Consensus on the parasite control was drafted in the Parasite Disease Prevention Act, which passed a parliamentary agreement in 1966, and established safe disposal of feces and mass chemotherapy as control strategies. Biannual stool examinations and treating infected schoolchildren were basic scheme of the control activity through which revenue could be secured for organized business. In the 27 years following 1969, a maximum of 16 million stool examinations had been done every year. Cellophane thick smear enabled the task. The infection declined remarkably in the 1970s when industrialization and green revolution proceeded. A population study of A. lumbricoides in the late 1970s helped us better understand its epidemiology. The data also settled down the understandable protest of teachers against the repeated stool examinations. In the 9 years following 1987, the target population was gradually reduced when the egg positive rate was below 0.1%. An article in the Korean Law, stipulating obligatory stool examinations, was made optional. Although the long-term Korean effort of Ascaris control was a success, the effect of mass chemotherapy was not as succinct in terms of lowering reinfection. In the period of control, Korean agricultural technology changed, and the economy grew and supplied sanitary facilities by which the vicious cycle was disconnected. Reduction of morbidity was a benefit of mass chemotherapy, which is the only control method feasible in economically difficult countries. The most important hurdle of parasite control in the 1960s was poverty of general population and limited financial resources in Korea but the society formed a consensus on the priority of intestinal helminthiasis control during the ordeal period. The national consensus in the 1960s was the critical milestone for Ascaris control in Korea. Under the social agreement, application of timely technical and research advancements in parasitology achieved the success of ascariasis elimination. The successful experience of ascariasis elimination in Korea can be a benchmark for countries where neglected tropical diseases are endemically recycled.