• Journal of Microbiology and Biotechnology
• /
• v.16 no.9
• /
• pp.1477-1480
• /
• 2006

The 63-amino-acid-encoding afsR2 is a global antibiotics-stimulating regulatory gene identified from the chromosome of Streptomyces lividans. To dissect a putative functional domain in afsR2, several afsR2-derivative deletion constructs were generated and screened for the loss of actinorhodin-stimulating capability. The afsR2-derivative construct missing a 50-bp C-terminal region significantly lost its actinorhodin-stimulating capability in S. lividans. In addition, site-directed mutagenesis on amino acid positions of #57-#61 in a 50-bp C-terminal region, some of which are conserved among known Sigma 70 family proteins, significantly changed the AfsR2's activity. These results imply that the C-terminal region of AfsR2 is functionally important for antibiotics-stimulating capability and the regulatory mechanism might be somehow related to the sigma-like domain present in the C-terminal of AfsR2.

• International Commerce and Information Review
• /
• v.13 no.4
• /
• pp.411-433
• /
• 2011

This article investigates the impacts of firms' regulatory compliance and voluntary innovation activities in environmental management on the development of their organizational capabilities and the enhancement of their performance, within the Korean context. The study invokes a structural equation analysis. The results indicate that voluntary innovation activity in response to market pressures makes a significant contribution to the development of firm-specific organizational capability and the enhancement of firms' performance, but regulatory compliance activity does not significantly affect either organizational capability or performance. This capability was also seen to have implications for firm's performance. This article also suggests several policy implications related to the research.

• Journal of Radiation Protection and Research
• /
• v.28 no.1
• /
• pp.65-73
• /
• 2003

The paper discusses results of recent international intercomparison exercises on internal dose assessments, status of up to date internal dosimetry methods and the radiological legislation developed and implemented in Korea, European Union and Ukraine. The system of radiation protection in Korea is based on the Korean Atomic Energy Regulatory Enforcement on Safety Standards (Ministry Notice No. 2001-2). The notice is based on the recommendations in ICRP Publication 60 (1990) and IAEA Basic Safety Standards (1996). But the full implementation of the notice by the end of the year 2002 is not required because of the socio-economic situation and inexperience in internal radiation dosimetry Regulatory framework for internal radiation dosimetry is under development toward the full implementation of the notice from January 1, 2003. The system of radiation protection in Ukraine is based on the National radiation protection regulatory code NRBU-97. The code was developed and adopted in 1998 and replaced the Regulations of Former Soviet Union. The document is based on the ICRP Publication 60, Euratom Directive 96/29 and IAEA Basic Safety Standards (1996). The transitional period of 5 years (effected till January 2003) is established for implementation of all requirements of this new regulation. The system of radiation protection in the European Community is based on the Council Directive 96/29/Euratom, adopted in 1996 and enforced from 13 May 2000. Directive 96/29/Euratom has the status of the European law.

• Korean Journal of Clinical Pharmacy
• /
• v.23 no.1
• /
• pp.71-76
• /
• 2013

Background (Purpose): The objective of this study was to investigate regulations on pharmacist and other healthcare professional license examination in Korea. Specific aim was focused on the implementation of new regulatory system governing pharmacist license examination particularly on naming of the subjects, method of the examination, and discrimination of pass or fail. Method: Laws and regulations of Korea on the examination system were retrieved from sources posted in Ministry of Government Legislation. Results: Two major regulatory differences were found between pharmacist and other healthcare professionals license examination systems. Firstly, the regulation on pharmacist license examination was ruled by the enforcement ordinance of parent law (Pharmacy Law) while it was ruled by enforcement regulation of parent law (Medical Law). Secondly, minimum grade requirement for pharmacist and other healthcare professionals was differently set up: 40% for each single subject in pharmacist and average of 40% for each group of several subjects in other healthcare professionals. Conclusion: Since pharmacist profession has drastically changed from drug-makers to drug-users during the recent decades, it is desirable to have the regulations on pharmacist license examination system amended in harmony with other laws and regulations of Korea and other major developed countries. Two-step examination for pharmacist license appears worthwhile to implement for balancing the two key functions of the pharmacist being drug-makers and drug-users.

• Environmental and Resource Economics Review
• /
• v.11 no.2
• /
• pp.233-260
• /
• 2002

This paper tries to analyze the efficiency structure and regulatory effects in electric power industry by using total factor productivity and indices based on cost function method. This paper performed an empirical analysis on the efficiency improvement and optimal scale taking the cost aspect in electricity industry into account. By expanding the cost structure framework, this paper proposes the analytical method regarding the needs of technology regulation and presents the empirical results which can be verified. Hence, this work can play a key role in decision-making of the national power development and regulatory policy. The empirical result indicates that the electricity industry in Korea has been in the state of economies of scale until 1980s, However, due to sustained growth of power generation, economies of scale declined and subsided after 1980s and then diseconomies of scale is shown recent years. The analysis on the effect of technology regulation shows the national large-scale base-load power plant development-oriented policy until so far contributed substantial cost effect to the electricity industry. The empirical result indicates that the reserve requirement as one of means of technology regulation policy did not contribute to the economies of scale but positive effect on the total factor productivity in Korea.

• Science of Emotion and Sensibility
• /
• v.15 no.1
• /
• pp.73-86
• /
• 2012

Consumers can have impression goals as well as defense goals. Those with impression goals could use social goals or opinions of others in a social context to determine their attitudes, and those with defense goals could maintain their existing attitudes and beliefs. Since people typically approach pleasure and avoid pain, there are two kinds of goal orientations depending on regulatory focus theory. Therefore, marketers could design advertisements for their products on the basis of two types of focus, promotion-focused and prevention-focused advertisements. This study aims to explore how consumers with different consumption goals evaluate an advertised product. The results of this study demonstrate that consumers with impression goals felt much more "right" about the product in a promotion-focused, rather than prevention-focused, advertisement, and those with defense goals, felt much more "right" about the product in a prevention-focused advertisement. Consumers with impression goals evaluated the product in the promotion-focused advertisement more favorably than in the prevention-focused advertisement, and those with defense goals evaluated the product in the prevention-focused advertisement more favorably.

• Asian Journal of Business Environment
• /
• v.7 no.2
• /
• pp.31-38
• /
• 2017

Purpose - While microfinance institutions(MFIs) from Bangladesh, such as Grameen Bank, received worldwide recognition and the Nobel Peace Prize in 2006, however, there is a paucity of research that provided a comprehensive discussion on the characteristics of the microfinance industry. Hence, the aim of this paper is to discuss some important aspects of the microfinance sector in Bangladesh. Research design, data, and methodology - This study used secondary sources of data, such as annual reports of the Microcredit Regulatory Authority (MRA) and the World Bank database in its descriptive analysis. Results - This study found that Bangladesh has made remarkable progress in her socio-economic and economic development in the last few decades. It is also generally perceived that microfinance has placed significant contribution on such socio-economic development. While microfinance observed unprecedented growth domestically, however, the regulatory framework is still rather weak, and a majority of the MFIs are found to be concentrated in the well-off areas (e.g., Dhaka, Chittagong etc.). Conclusions - The findings are significantly important for the parties who are interested to know the microfinance sector in Bangladesh. To some extent, the findings of this study will provide policy implications that may benefit the industry.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.11 no.9
• /
• pp.1634-1641
• /
• 2007

In this paper, We examine the point at issue of domestic telecommunications and standards. In Korea, since we can't lighten effectively the regulatory due to operate separately both of Regulations and Standards, we should convert regulation regulatory into standard regulatory through the correlation between Regulations and Standards. In the view of expected effect, practical use for consolidating the establishment and amendment of the national telecommunications standards, and making the consolidation plan of standardization Acts and practical use for making the correlation plan between the telecommunication regulations and standards.

• Nuclear Engineering and Technology
• /
• v.42 no.6
• /
• pp.690-703
• /
• 2010

Sampling based uncertainty analysis was carried out to quantify uncertainty in predictions of best estimate code RELAP5/MOD3.2 for a thermal hydraulic test (10% hot leg break LOCA) performed in the Large Scale Test Facility (LSTF) as a part of an IAEA coordinated research project. The nodalisation of the test facility was qualified for both steady state and transient level by systematically applying the procedures led by uncertainty methodology based on accuracy extrapolation (UMAE); uncertainty analysis was carried out using the Latin hypercube sampling (LHS) method to evaluate uncertainty for ten input parameters. Sixteen output parameters were selected for uncertainty evaluation and uncertainty band between $5^{th}$ and $95^{th}$ percentile of the output parameters were evaluated. It was observed that the uncertainty band for the primary pressure during two phase blowdown is larger than that of the remaining period. Similarly, a larger uncertainty band is observed relating to accumulator injection flow during reflood phase. Importance analysis was also carried out and standard rank regression coefficients were computed to quantify the effect of each individual input parameter on output parameters. It was observed that the break discharge coefficient is the most important uncertain parameter relating to the prediction of all the primary side parameters and that the steam generator (SG) relief pressure setting is the most important parameter in predicting the SG secondary pressure.

• Nuclear Engineering and Technology
• /
• v.49 no.3
• /
• pp.517-524
• /
• 2017

Cyber security is an important issue in the field of nuclear engineering because nuclear facilities use digital equipment and digital systems that can lead to serious hazards in the event of an accident. Regulatory agencies worldwide have announced guidelines for cyber security related to nuclear issues, including U.S. NRC Regulatory Guide 5.71. It is important to evaluate cyber security risk in accordance with these regulatory guides. In this study, we propose a cyber security risk evaluation model for nuclear instrumentation and control systems using a Bayesian network and event trees. As it is difficult to perform penetration tests on the systems, the evaluation model can inform research on cyber threats to cyber security systems for nuclear facilities through the use of prior and posterior information and backpropagation calculations. Furthermore, we suggest a methodology for the application of analytical results from the Bayesian network model to an event tree model, which is a probabilistic safety assessment method. The proposed method will provide insight into safety and cyber security risks.