• Asian Pacific Journal of Cancer Prevention
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• 제17권6호
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• pp.3021-3023
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• 2016

The significance, difficulty and strategy of coding cancer data according to international coding standards are discussed, and the concept, methods and realization of cancer data automatic coding in cancer registries in China are introduced in the paper. Coding cancer data automatically with software could not only reduce the time, manpower and workload, while improving the accuracy and efficiency of cancer data coding, but also enhance the validity of cancer registration and the value of cancer registry data, which is of great significance.

• Translational and Clinical Pharmacology
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• 제26권4호
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• pp.172-176
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• 2018

Mandatory registration of clinical trials in public registry can ensure the transparency of clinical trials. Public clinical trial registry of can provide current chronological and geographical distribution of clinical trial throughout the country. We used public clinical trial registry provided by Ministry of Food and Drug Safety to analyze current status of clinical trial from 2014 to 2016 in South Korea. The number of clinical trials in antineoplastic and immunomodulating agents area was the greatest, followed by cardiovascular system and antiinfectives for systemic use as a whole. From 2014 to 2016, overall number of clinical trials decreased while the number of phase I clinical trials increased. Seoul accounted for more than half number of clinical trials in Korea. Supports for clinical trials in non-metropolitan area needs to be considered.

• 대한한방내과학회지
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• 제41권6호
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• pp.959-966
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• 2020

Objectives: To examine the fundamental characteristics of interventional clinical trials registered in the CRIS (Clinical Research Information Service) database. Methods: We systematically analyzed the status of Korean medical interventions using the search function of the CRIS database. Results: From 2010 to January 2020, 267 Korean medicine-related clinical trials were registered with CRIS. The studies, which included many randomized trials (80.14%), focused primarily on demonstrating the effectiveness and safety of acupuncture and Korean herbal remedies. Most of these studies were government-sponsored and researcher-led clinical trials, but a few were company-sponsored trials. All trials were small and need improvement. Conclusion: This study reviews the current status of clinical trials in the field of Korean medicine and the basic data that can be used to create evidence-based Korean medicine.

• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.4387-4392
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• 2013

Projection of load of cancer mortality helps in quantifying the burden of cancer and is essential for planning cancer control activities. As per our knowledge, there have not been many attempts to project the cancer mortality burden at the country level in India mainly due to lack of data on cancer mortality at the national and state level. This is an attempt to understand the magnitude of cancer mortality problem for the various calendar years from 2011 to 2026 at 5-yearly intervals. Age, sex and site-wise specific cancer mortality data along with populations covered by the registries were obtained from the report of National Cancer Registry Programme published by Indian Council of Medical Research for the period 2001-2004. Pooled age sex specific cancer mortality rates were obtained by taking weighted average of these six registries with respective registry populations as weights. The pooled mortality rates were assumed to represent the country's mortality rates. Populations of the country according to age and sex exposed to the risk of cancer mortality in different calendar years were obtained from the report of Registrar General of India providing population projections for the country for the years from 2011 to 2026. Population forecasts were combined with the pooled mortality rates to estimate the projected number of cancer mortality cases by age, sex and site of cancer at various 5-yearly periods Viz. 2011, 2016, 2021 and 2026. The projections were carried out for the various cancer-leading sites as well as for 'all sites' of cancer. The results revealed that an estimated 0.44 million died due to cancer during the year 2011, while 0.51 million and 0.60 million persons are likely to die from cancer in 2016 and 2021. In the year 2011 male mortality was estimated to be 0.23 million and female mortality to be 0.20 million. The estimated cancer mortality would increase to 0.70 million by the year 2026 as a result of change in size and composition of population. In males increase will be to 0.38 millions and in females to 0.32 millions. Among women, cancer of the breast, cervical and ovary account for 34 percent of all cancer deaths. The leading sites of cancer mortality in males are lung, oesophagus, prostrate and stomach. The above results show a need for commitment for tackling cancer by reducing risk factors and strengthening the existing screening and treatment facilities.

• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.4379-4386
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• 2013

Projection of cancer incidence is essential for planning cancer control actions, health care and allocation of resources. Here we project the cancer burden at the National and State level to understand the magnitude of cancer problem for the various calendar years from 2011 to 2026 at 5-yearly intervals. The age, sex and site-wise cancer incidence data along with populations covered by the registries were obtained from the report of National Cancer Registry Programme published by Indian Council of Medical Research for the period 2001-2004. Pooled age sex specific cancer incidence rates were obtained by taking weighted averages of these seventeen registries with respective registry populations as weights. The pooled incidence rates were assumed to represent the country's incidence rates. Populations of the country according to age and sex exposed to the risk of development of cancer in different calendar years were obtained from the report of Registrar General of India providing population projections for the country for the years from 2001 to 2026. Population forecasts were combined with the pooled incidence rates to estimate the projected number of cancer cases by age, sex and site of cancer at various 5-yearly periods Viz. 2011, 2016, 2021 and 2026. The projections were carried out for the various leading sites as well as for 'all sites' of cancer. In India, in 2011, nearly 1,193,000 new cancer cases were estimated; a higher load among females (603,500) than males (589,800) was noted. It is estimated that the total number of new cases in males will increased from 0.589 million in 2011 to 0.934 million by the year 2026. In females the new cases of cancer increased from 0.603 to 0.935 million. Three top most occurring cancers namely those of tobacco related cancers in both sexes, breast and cervical cancers in women account for over 50 to 60 percent of all cancers. When adjustments for increasing tobacco habits and increasing trends in many cancers are made, the estimates may further increase. The leading sites of cancers in males are lung, oesophagus, larynx, mouth, tongue and in females breast and cervix uteri. The main factors contributing to high burden of cancer over the years are increase in the population size as well as increase in proportion of elderly population, urbanization, and globalization. The cancer incidence results show an urgent need for strengthening and augmenting the existing diagnostic/treatment facilities, which are inadequate even to tackle the present load.

• Asian Pacific Journal of Cancer Prevention
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• 제17권12호
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• pp.5211-5216
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• 2016

Background: Breast cancer is the most frequently diagnosed malignancy and the leading cause of cancer death among women worldwide. In Morocco, there have been few recent descriptive studies on female breast cancer. The aim of this study was to describe the latest available incidence and mortality rates of breast cancer among Moroccan women and to compare them with rates in other regional and Western countries. Methods: For this descriptive study, Moroccan incidence data were obtained from the most recent reports of the cancer registries of Casablanca and Rabat. Information on breast cancer incidence for different countries were obtained primarily from publicly available cancer registries and Cancer Incidence in Five Continents, Volume X. Mortality data were extracted from the GLOBOCAN 2012 published by the International Agency for Research on Cancer. Results: The age-standardized incidence (World) rate of breast cancer in Moroccan women increased from 35.0 to 39.0 per 100,000 women between 2004 and 2008, showing an annual increase of 2.85 %. The highest incidence rates were registered in the age groups of 45-49, 50-54 and 55-59 years (106.1, 108.2 and 108.5 respectively). Sixty-nine percent of female breast cancer cases were diagnosed at stages II and III. In 2012, the estimated number of women who died of breast cancer in Morocco was 2,878. The crude, age-standardized (World) mortality rates were 17.3 and 18.0 per 100,000, respectively. Conclusion: Although the incidence of female breast cancer in Morocco is lower than in Western countries, evidence shows that the rate is rising. This increase of breast cancer incidence has been observed in parallel with changes in reproductive behavior and adoption of a Western lifestyle. Prevention policies need to be implemented.

• 정보처리학회논문지D
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• 제14D권4호
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• pp.435-446
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• 2007

B2B 등록저장소는 기엽의 프로파일, 비즈니스 문서, 비즈니스 프로세스, 제공 서비스 등의 B2B 관련 비즈니스 정보들을 저장하고 거래 파트너 또는 잠재 거래 파트너들에게 정보를 제공하는 시스템이다. 본 논문에서는 이 중 B2B 비즈니스 프로세스의 등록저장소의 설계에 초점을 맞추어, 이를 지원하기 위한 메타데이터 온톨로지를 제시한다. 현재 ebXML BPSS (Business Process Specification Schema), WSBPEL (Web Service Business Process Execution Language), BPMN (Business Process Modeling Notation) 등의 다수의 비즈니스 프로세스 정의 언어들이 시장에서 경쟁하고 있다. 이러한 상황을 고려하여, 다수의 다른 프레임워크에서 표현된 비즈니스 프로세스를 등록저장하기 위해서 제시된 메타 데이터 온톨로지는 3개 계층, 공통 메타데이터, 언어별 메타데이터, 상호연관관계 메타데이터로 구성된다. 제시된 메타데이터 온톨로지의 유용성을 보이기 위해서, ebXML BPSS 와 WSBPEL로 표현된 비즈니스 프로세스의 온톨로지 내에 저장을 예제로 제시한다. 또한 제시된 메타데이터 온톨로지의 구현을 위해서 ebXML 등록저장소 정보모델로의 매핑 방안을 제시한다.

• 한국콘텐츠학회논문지
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• 제7권11호
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• pp.9-22
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• 2007

전자문서와 같이 기업간거래에 관한 정보자원의 등록저장 및 공유에 있어서 표준화와 활용은 상당한 진척이 이루어졌으나, 비즈니스 프로세스의 경우 이를 정의하는 방법이 다양하고 복잡한 이유로 비즈니스 프로세스 정보자원의 등록저장 및 공유에는 어려움이 많다. 실제로 ebXML BPSS, WS-BPEL, BPMN 등과 같이 서비스 지향 아키텍쳐 하에서 활용가능한 여러 비즈니스 프로세스 정의 언어들이 시장에서 경쟁하고 있으며, 이들을 이용해서 표현된 다양하고 이질적인 비즈니스 프로세스 명세(정의)들을 체계적으로 등록저장하기 위한 방안이 절실히 필요한 상황이다. 이 논문에서는 ebRR4BP라고 하는 기업간 비즈니스 프로세스 등록저장소 프로토타입을 개발하여, 기업간 비즈니스 프로세스 공유의 유용함을 제시하고자 한다. 이를 위해서 먼저 다양한 기업간 비즈니스 프로세스 등록을 위한 메타데이터 온톨로지를 설계하고, 이를 ebXML 등록저장소에 구현할 수 있도록 ebXML 등록저장소 정보모델로 매핑하는 방안도 구체적으로 제시한다. 이러한 온톨로지와 매핑방안은 기업간거래 등록저장소간의 비즈니스 프로세스 메타데이터의 상호교환을 지원하기 위한 밑바탕이 될 것이다.

• Archives of Plastic Surgery
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• 제44권3호
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• pp.217-222
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• 2017

Background The prevalence of flap necrosis after palatoplasty in patients with cleft palate. The prevalence of mucoperiosteal flap necrosis after palatoplasty remains unknown, and this complication is rare. This event is highly undesirable for both the patient and the surgeon. We present here a new scale to evaluate the degree of hypoplasia of the palate and identify patients with cleft palate at high risk for the development of this complication. Methods In this case series, a 20-year retrospective analysis (1994-2014) identified patients from our records (medical records and screening day registries) with nonsyndromic cleft palate who underwent operations at 3 centers. All of these patients underwent operations using 2-flap palatoplasty and also underwent a physical examination with photographs and documentation of the presence of palatal flap necrosis after primary palatoplasty. Results Palatal flap necrosis was observed in 4 cases out of 1,174 palatoplasties performed at these centers. The observed prevalence of palatal flap necrosis in these groups was 0.34%. Conclusions The prevalence of flap necrosis can be reduced by careful preoperative planning, and prevention is possible. The scale proposed here may help to prevent this complication; however, further studies are necessary to validate its utility.

• Asian Pacific Journal of Cancer Prevention
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• 제17권10호
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• pp.4775-4782
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• 2016

Background: Cancer incidence data are vital for cancer control planning in any nation. This retrospective study was conducted to compare the cancer incidence of all sites between the first cancer registry report and the most recent example in Nepal. Material and Methods: The cases in the first (2003) and latest (2013) national cancer registry reports, accumulated by all the hospital based cancer registries in Nepal were taken for the research. The frequencies, crude incidences and age specific incidences (per 100,000) of the five major cancers were calculated for both males and females. Result: The most common cancer type for males in both years 2003 and 2013 was lung. Stomach was the third most common cancer in 2003 while it was the second in 2013. Similarly, the first four major cancers (cervix, breast, lung and ovary) did not change between 2003 and 2013 in females. The total cancer incidence rate increased from 12.8 in 2003 to 30.4 per 100,000 in 2013 for males and from 15.1 to 33.3 in females. Conclusion: The most common cancers in males in 2003 and 2013 were the bronchus and lung. Similarly, the most common cancer in females was cervix at both time points. The cancer incidence rate in females was higher than in males both in 2003 and 2013.