• Journal of Trauma and Injury
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• v.23 no.1
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• pp.6-15
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• 2010

Purpose: Trauma is one of the leading causes of death, especially among young people. Life-threatening conditions are very common in multiple-traumatized patients due to concurrent multi-organ injuries. Treating such severely injured patients is time critical. However, in Korea, the transfer of severely injured patients is not uncommon due to the lack of a mature trauma care system. In developed countries, the preventable trauma death rate is very low, but the rate is still very high in Korea. This study's objective was to demonstrate the current serious state in which severely injured patients have to be transferred from a Regional Emergency Medical Center even though it actually serves as a trauma center. Methods: Ajou University Medical Center is a tertiary hospital that serves as a trauma center in Gyeonggido. The medical records at Ajou University Medical Center for a 1-year period from January 1, 2008, to December 31, 2008, were retrospectively reviewed. A severely injured patient was defined as a patient who showed more than 15 point on the ISS (injury severity score) scale. We investigated the clinical characteristics of such patients and the causes of transfer. Results: Out of 81,718 patients who visited the Regional Emergency Medical Center, 19,731 (24.1%) were injured patients. Among them, 108 severely-injured patients were transferred from one Regional Emergency Medical Center to other hospitals. The male-to-female ratio was about 3.5:1, and the mean ISS was 23.08. The most common mechanism of injury was traffic accidents (41.7%). A major cause of transfer was the shortage of intensive care units (44.4%); another was for emergent operation (27.8%). Most of the hospitals that received the severely-injured patients were secondary hospitals (86.1%). Conclusion: Although the Regional Emergency Medical Center played a role as a trauma center, actually, severely-injured patients had to be transferred to other hospitals for several reasons. Most reasons were related with the deficiencies in the trauma care system. If a mature trauma care system is well-organized, the numbers of transfer of severely injured patients will be reduced significantly.

• Land and Housing Review
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• v.4 no.1
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• pp.89-98
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• 2013

In recent years, it was recognized that aurban policy paradigm of sustainable urban growth management and transportation policies have been shifted : from the era of automobile-oriented policy to the era of public transport policy. Against this backdrop, the introduction of the multi-modal transfer center is very consequential. Therefore, it is necessary for the introduction of wide-area and local-centric transfer facilities, as well as the center of the country-led national backbone transfer center. This study was applicable at the multi-modal transfer center plans to introduce guidelines to provide transit facilities, considering the regional and functional characteristics to classify the types of multi-modal transfer center. The final types of multi-modal transfer center were classified into six, and by considering the combination of the criteria to be classified. The multi-modal transfer center type classification based on the case analysis of the types of facilities at domestic and abroad. If the data of multi-modal transfer are accumulated continuously, can expect a more reliable type classification.

• Journal of Preventive Medicine and Public Health
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• v.55 no.4
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• pp.351-359
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• 2022

Objectives: The Regional CardioCerebroVascular Center (RCCVC) project was initiated to improve clinical outcomes for patients with acute myocardial infarction or stroke in non-capital areas of Korea. The purpose of this study was to evaluate the outcomes and issues identified by the Busan RCCVC project in the treatment of ST-segment elevation myocardial infarction (STEMI). Methods: Among the patients who were registered in the Korean Registry of Acute Myocardial Infarction for the RCCVC project between 2007 and 2019, those who underwent percutaneous coronary intervention (PCI) for STEMI at the Busan RCCVC were selected, and their medical data were compared with a historical cohort. Results: In total, 1161 patients were selected for the analysis. Ten years after the implementation of the Busan RCCVC project, the median door-to-balloon time was reduced from 86 (interquartile range [IQR], 64-116) to 54 (IQR, 44-61) minutes, and the median symptom-to-balloon time was reduced from 256 (IQR, 180-407) to 189 (IQR, 118-305) minutes (p<0.001). Inversely, the false-positive PCI team activation rate increased from 0.6% to 21.4% (p<0.001). However, the 1-year cardiovascular death and major adverse cardiac event rates did not change. Even after 10 years, approximately 75% of the patients had a symptom-to-balloon time over 120 minutes, and approximately 50% of the patients underwent inter-hospital transfer for primary PCI. Conclusions: A decade after the implementation of the Busan RCCVC project, although time parameters for early reperfusion therapy for STEMI improved, at the cost of an increased false-positive PCI team activation rate, survival outcomes were unchanged.

• Health Policy and Management
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• v.33 no.4
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• pp.440-449
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• 2023

Background: This study aimed to analyze the prehospital process and reperfusion therapy process of acute ischemic stroke in Busan metropolitan area and examine the impact of living arrangement on the early management and functional outcomes of acute ischemic stroke (AIS). Methods: The patients who diagnosed with AIS and received reperfusion therapy at the Busan Regional Cardiovascular Center between September 2020 and May 2023 were selected. We investigated the patients' hospital arrival time (onset to door time) and utilization of 119 emergency ambulance services. Additionally, various time matrices related to reperfusion therapy after hospital were examined, along with the functional outcome at the 90-day after treatment. Results: Among the 753 AIS patients who underwent reperfusion therapy, 166 individuals (22.1%) were living alone. AIS patients living alone experienced significant delays in symptom detection (p<0.05) and hospital arrival compared to AIS patients with cohabitants (370.1 minutes vs. 210.2 minutes, p<0.001). There were no significant differences between the two groups in terms of 119 ambulance utilization and time metrics related with the reperfusion therapy. Independent predictors of prognosis in AIS patients were found to be age above 70, National Institutes of Health Stroke Scale score at admission, tissue plasminogen activator, living alone (odds ratio [OR], 1.785; 95% confidence interval [CI], 1.155-2.760) and interhospital transfer (OR, 1.898; 95% CI, 1.152-3.127). Delay in identification of AIS was shown significant correlation (OR, 2.440; 95% CI, 1.070-5.561) at living alone patients. Conclusion: This study revealed that AIS patients living alone in the Busan metropolitan region, requiring endovascular treatment, face challenges in the pre-hospital phase, which significantly impact their prognosis.

• Journal of Technology Innovation
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• v.13 no.2
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• pp.157-178
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• 2005

During the transformation of the agro-technology extension in rural China, many new Policy experiments are emerging to rebuild the lost linkages and to improve technology transfer with the system and among systems. Applying the Triple Helix Model of academy-agriculture-government relations, this paper explores a new pattern of technology transfer with the case of BaojiCity. The authors interpret the mechanism of 'Courtyards for Agro-experts', as well as the comparison between different types of courtyards. This article concludes that the Triple Helix in the agro-sector improves technology transfer and accelerates knowledge-based regional development. In the interest of farmers there should also be concern over reducing inequity the reform.

• Proceedings of the KSR Conference
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• 2011.05a
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• pp.775-789
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• 2011

Centering on KTX stations, Korea is implementing specialized development of metropolitan business zones nationwide and is in the process of building the transfer link system of transportation in order to actualize intermodalism nationwide. Daejeon station, hub of high-speed railway requires the effective transportation transfer system considering Daejeon station area reorganization plan and opening of second phase high-speed railway. Based on the analysis of the possibility and validity of building a transit center under the Transportation System Efficiency Act, it is necessary to make a mutual benefit in a regional development by installing the resonable transfer system between railway and other transportation services. Through analysis of current situations and technical, economic and environmental feasibility evaluation, design plan of effective transportation transfer system in Daejeon station is proposed.

• Journal of Korea Technology Innovation Society
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• v.8 no.3
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• pp.955-985
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• 2005

This paper describes the evolutionary trajectory of the missions of public research institutes(PRIs) in Korea since 1960s and analyses the newly highlighted role of PRIs as the facilitators of regional innovation system, with questionnaire surveys and the case study of Gwangju Institute of Science and Technology(GIST). PRIs have played important roles in Korean rapid economic development by introducing and improving foreign high-technologies in 1970s and 1980s and by creating new advanced high-technologies in 1990s. In recent years, the functions as regional technology innovators have been considered important as regional innovation system has come to the center of discussion. According to the result of this study, Korean PRIs have recognized their roles relevant to regional innovation, such as developing the technologies of regional strategic industries and awakening regional innovative actors to a sense of research. Regardless of the functions as industrial technology suppliers, however, the bilateral networks between PRIs and regional industries are not revealed strong, whereas those with universities and other research institutes are relatively strong. In addition, the research cooperation of PRIs with regional innovative actors are different by where they are located. The case of GIST shows how a regional PRI operates, commercializes its academic achievement and encourages the regional transfer of the achievement systematically. Finally, this study draws some policy implications on developing regional PRIs.

• BMB Reports
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• v.42 no.10
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• pp.642-647
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• 2009

In this study, the effects of $Ca^{2+}$ and cyclic adenosine monophosphate (cAMP) on microsomal triglyceride (TG) transfer protein (MTP) activity were investigated in rat liver. MTP activity was high when liver contained low levels of cAMP, which was induced by administration of glucose, or high levels of total $Ca^{2+}$ and TG. However, MTP activity increased by high levels of $Ca^{2+}$ and TG was reduced in a dose-dependent manner by treatment with dibutyryl-cAMP (db-cAMP), a cAMP analogue. Conversely, when homogenates of liver from normal rats, with low levels of total $Ca^{2+}$ and high levels of cAMP, were incubated with thapsigargin, a $Ca^{2+}$-inducer, MTP activity was increased in a dose-dependent manner compared to control. Therefore, our results suggest that high levels of $Ca^{2+}$ cause hypertriglyceridemia through the elevation of MTP activity, as opposed to high levels of cAMP, which suppress MTP activity and inhibit hypertriglyceridemia.

• Proceedings of the SAREK Conference
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• 2006.06a
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• pp.1107-1112
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• 2006

The purpose of this study is a heat transfer coefficient test of evaporator tube in shell and tube heat exchanger by shapes, using R-404A. The experimental apparatus is designed to simulate the real heat transfer rate in one shell and tube heat exchanger. The test section is formed four type tubes that are Inner ridged tube, Corrugated tube, Turbo-C tube, Inner fin tube and shell type is formed by electrical heater. All tests were performed at a fixed refrigerant evaporator temperature at $1.5^{\circ}C,\;-3^{\circ}C$ and with mass fluxes of 29, 25 kg/hr. Heat transfer rate is calculated a enthalpy difference in test section. In experiment, heat transfer coefficient measured one by one and electrical heaters are supplemented by evaporator.

• Korean Chemical Engineering Research
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• v.57 no.3
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• pp.351-357
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• 2019

This research was performed to propose domestic standard for design and management of flexible hose by analyzing chlorine leak caused by breakage of the hose in Ulsan, 2018. The leak had multiple causes but this paper focuses on analyzing the cause of breakage of flexible hose, the direct cause. According to the analysis, flexible hose that the company of the accident used for chlorine transfer was inappropriate in several aspects including material and wall thickness. And even pressure test had been conducted below operating pressure. Upon investigation on five companies that handle chlorine in Ulsan, four companies were using inappropriate flexible hose for chlorine transfer. Since there is no domestic standard for the design of flexible hose for chlorine transfer at present, it is hard to examine its design adequacy. Design standard of flexible hose used in chlorine transfer that is applicable domestically is proposed based on this research. It will contribute to the reduction in risk of breakage of the hose if the proposed standard could be applied in design and examination of flexible hose.