• Title/Summary/Keyword: Regensburg

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Effects of electrostimulation therapy in facial nerve palsy

  • Sommerauer, Laura;Engelmann, Simon;Ruewe, Marc;Anker, Alexandra;Prantl, Lukas;Kehrer, Andreas
    • Archives of Plastic Surgery
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    • v.48 no.3
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    • pp.278-281
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    • 2021
  • Facial palsy (FP) is a functional disorder of the facial nerve involving paralysis of the mimic muscles. According to the principle "time is muscle," early surgical treatment is tremendously important for preserving the mimic musculature if there are no signs of nerve function recovery. In a 49-year-old female patient, even 19 months after onset of FP, successful neurotization was still possible by a V-to-VII nerve transfer and cross-face nerve grafting. Our patient suffered from complete FP after vestibular schwannoma surgery. With continuous application of electrostimulation (ES) therapy, the patient was able to bridge the period between the first onset of FP and neurotization surgery. The significance of ES for mimic musculature preservation in FP patients has not yet been fully clarified. More attention should be paid to this form of therapy in order to preserve the facial musculature, and its benefits should be evaluated in further prospective clinical studies.

Regensburg as Bibliographic Destination for Traveling Scholars of the Eighteenth-Century

  • Walker, Thomas D.
    • Journal of Information Science Theory and Practice
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    • v.3 no.2
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    • pp.31-41
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    • 2015
  • The Bavarian town of Regensburg was a library travel destination during the European Enlightenment. With at least 26 collections, the number and variety of its private, governmental, school, and religious libraries rivaled that of much larger cities and figured in the bibliographic travel accounts of Johann Keyssler, Christoph Nicolai, Carl Oelrichs, Filippo Argellati, Georg Zapf, Friedrich Hirsching, Adalbert Blumenschein, and many others. The first-hand descriptions of these repositories are unique primary sources for the study of library history. Having been accessible to researchers largely in published forms, many were designed to serve as bibliographic aids for informing scholars about the locations of specialized subject collections and some individual works. The journals, letters, guidebooks, and texts also reflected the evolving scholarly and scientific nature of their cultural period. Overall, this case study of Regensburg’s libraries illustrates the particular value of contemporary travel literature.

Biofilm formation on denture base resin including ZnO, CaO, and TiO2 nanoparticles

  • Anwander, Melissa;Rosentritt, Martin;Schneider-Feyrer, Sibylle;Hahnel, Sebastian
    • The Journal of Advanced Prosthodontics
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    • v.9 no.6
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    • pp.482-485
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    • 2017
  • PURPOSE. This laboratory study aimed to investigate the effect of doping an acrylic denture base resin material with nanoparticles of ZnO, CaO, and $TiO_2$ on biofilm formation. MATERIALS AND METHODS. Standardized specimens of a commercially available cold-curing acrylic denture base resin material were doped with 0.1, 0.2, 0.4, or 0.8 wt% commercially available ZnO, CaO, and $TiO_2$ nanopowder. Energy dispersive X-ray spectroscopy (EDX) was used to identify the availability of the nanoparticles on the surface of the modified specimens. Surface roughness was determined by employing a profilometric approach; biofilm formation was simulated using a monospecies Candida albicans biofilm model and a multispecies biofilm model including C. albicans, Actinomyces naeslundii, and Streptococcus gordonii. Relative viable biomass was determined after 20 hours and 44 hours using a MTT-based approach. RESULTS. No statistically significant disparities were identified among the various materials regarding surface roughness and relative viable biomass. CONCLUSION. The results indicate that doping denture base resin materials with commercially available ZnO, CaO, or $TiO_2$ nanopowders do not inhibit biofilm formation on their surface. Further studies might address the impact of varying particle sizes as well as increasing the fraction of nanoparticles mixed into the acrylic resin matrix.

Polyvinyl butyral DMN-conjugates for the controlled release of singlet oxygen in medical and antimicrobial applications

  • Posavec, Damir;Muller, Rainer;Bogner, Udo;Bernhardt, Gunther;Knor, Gunther
    • Biomaterials and Biomechanics in Bioengineering
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    • v.1 no.2
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    • pp.73-79
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    • 2014
  • Covalent attachment of 1, 4-dimethylnaphthalene (DMN) based endoperoxide forming subunits to a polyvinyl butyral (PVB) backbone has been achieved. The functionalized polymer materials prepared and characterized here can serve as biocompatible carrier systems for studying cellular uptake, intermediate storage and delayed release of singlet oxygen, which opens up new doors for optimizing a variety of medical applications of photogenerated DMN-endoperoxides such as antiviral, antibacterial, antiplasmodial and antitumor activity.

In vitro performance and fracture resistance of novel CAD/CAM ceramic molar crowns loaded on implants and human teeth

  • Preis, Verena;Hahnel, Sebastian;Behr, Michael;Rosentritt, Martin
    • The Journal of Advanced Prosthodontics
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    • v.10 no.4
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    • pp.300-307
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    • 2018
  • PURPOSE. To investigate the fatigue and fracture resistance of computer-aided design and computer-aided manufacturing (CAD/CAM) ceramic molar crowns on dental implants and human teeth. MATERIALS AND METHODS. Molar crowns (n=48; n=8/group) were fabricated of a lithium-disilicate-strengthened lithium aluminosilicate glass ceramic (N). Surfaces were polished (P) or glazed (G). Crowns were tested on human teeth (T) and implant-abutment analogues (I) simulating a chairside (C, crown bonded to abutment) or labside (L, screw channel) procedure for implant groups. Polished/glazed lithium disilicate (E) crowns (n=16) served as reference. Combined thermal cycling and mechanical loading (TC: $3000{\times}5^{\circ}C/3000{\times}55^{\circ}C$; ML: $1.2{\time}10^6$ cycles, 50 N) with antagonistic human molars (groups T) and steatite spheres (groups I) was performed under a chewing simulator. TCML crowns were then analyzed for failures (optical microscopy, SEM) and fracture force was determined. Data were statistically analyzed (Kolmogorow-Smirnov, one-way-ANOVA, post-hoc Bonferroni, ${\alpha}=.05$). RESULTS. All crowns survived TCML and showed small traces of wear. In human teeth groups, fracture forces of N crowns varied between $1214{\pm}293N$ (NPT) and $1324{\pm}498N$ (NGT), differing significantly ($P{\leq}.003$) from the polished reference EPT ($2044{\pm}302N$). Fracture forces in implant groups varied between $934{\pm}154N$ (NGI_L) and $1782{\pm}153N$ (NPI_C), providing higher values for the respective chairside crowns. Differences between polishing and glazing were not significant ($P{\geq}.066$) between crowns of identical materials and abutment support. CONCLUSION. Fracture resistance was influenced by the ceramic material, and partly by the tooth or implant situation and the clinical procedure (chairside/labside). Type of surface finish (polishing/glazing) had no significant influence. Clinical survival of the new glass ceramic may be comparable to lithium disilicate.

Influence of zirconia and lithium disilicate tooth- or implant-supported crowns on wear of antagonistic and adjacent teeth

  • Rosentritt, Martin;Schumann, Frederik;Krifka, Stephanie;Preis, Verena
    • The Journal of Advanced Prosthodontics
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    • v.12 no.1
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    • pp.1-8
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    • 2020
  • PURPOSE. To investigate the influence of crown material (lithium-disilicate, 3Y-TZP zirconia) and abutment type (rigid implant, resin tooth with artificial periodontium) on wear performance of their antagonist teeth and adjacent teeth. MATERIALS AND METHODS. A mandibular left first molar (#36) with adjacent human teeth (mandibular left second premolar: #35, mandibular left second molar: #37) and antagonistic human teeth (maxillary left second premolar: #25, maxillary left first molar: #26, maxillary left second molar: #27) was prepared simulating a section of the jaw. Samples were made with extracted human molars (Reference), crowned implants (Implant), or crowned resin tooth analogues (Tooth). Crowns (tooth #36; n = 16/material) were milled from lithium-disilicate (Li, IPS e.max CAD) or 3Y-TZP zirconia (Zr, IPS e.max ZirCAD, both Ivoclar Vivadent). Thermal cycling and mechanical loading (TCML) in the chewing simulator were applied simulating 15 years of clinical service. Wear traces were analyzed (frequency [n], depth [㎛]) and evaluated using scanning electron pictures. Wear results were compared by one-way-ANOVA and post-hoc-Bonferroni (α = 0.05). RESULTS. After TCML, no visible wear traces were found on Zr. Li showed more wear traces (n = 30-31) than the reference (n = 21). Antagonistic teeth #26 showed more wear traces in contact to both ceramics (n = 27-29) than to the reference (n = 21). Strong wear traces (> 350 ㎛) on antagonists and their adjacent teeth were found only in crowned groups. Abutment type influenced number and depth of wear facets on the antagonistic and adjacent teeth. CONCLUSION. The clinically relevant model with human antagonistic and adjacent teeth allowed for a limited comparison of the wear situation. The total number of wear traces and strong wear on crowns, antagonistic and adjacent teeth were influenced by crown material.

TREATMENT OF ANIMAL MANURE AND WASTES FOR ULTIMATE DISPOSAL - Review -

  • Winter, J.;Hilpert, R.;Schmitz, H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.5 no.2
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    • pp.199-215
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    • 1992
  • Sources of organic waste materials for aerobic and/or anaerobic degradation, or for composting of solid wastes in Germany were estimated. The basic microbiology and the energetics of these processes were compared with special emphasis on anaerobic degradation, for which a general degradation scheme of carbohydrates is presented. Advantages of anaerobic over aerobic treatment processes are pointed out and conditions for maintaining a highly stable anaerobic process as well as producing a sanitized, hygienic product are discussed. Reactor systems suitable for efficient treatment of wastes with a high or low proportion of suspended solids are principally compared and results of laboratory studies on the degradation of several wastes and animal manures summarized. Finally, a piggery slurry treatment factory for an ultimate slurry processing to obtain a dry fertilizer and a harmless, disposable liquid, as it is in operation in Helmond/Holland, is presented and preliminary process data are presented.

Optically Active Intermediate from the Degradation of (-)-Laudanosine, a Benzylisoquinoline Alkaloid, with Ethyl Chloroformate

  • Dong-Ung Lee;W. Wiegrebe
    • Bulletin of the Korean Chemical Society
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    • v.12 no.4
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    • pp.373-376
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    • 1991
  • Degradation of (-)-laudanosine, a 1-benzyl-1,2,3,4-tetrahydroisoquinoline alkaloid, with ethyl chloroformate (ECF) afforded an optically active chloro-carbamate as an intermediate. The reason why this intermediate exhibits an optical activity was investigated by comparison with the reactions of some model compounds with ECF. It may be supposed that the chloride group in a hypothetic carbenium ion intermediate stands very closely to the chiral center, so conserving optical activity. However, a neighboring group effect can not be excluded.