• 제목/요약/키워드: Refractory symptoms

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Clinical Features in 9 Dogs with Immune-Mediated Polyarthritis

  • Lim, Seula;Song, Kun-Ho;Seo, Kyoung-Won
    • Journal of Veterinary Clinics
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    • 제34권6호
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    • pp.434-436
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    • 2017
  • Nine dogs with history of lameness and anorexia were presented. On physical examination, all dogs had gait abnormality and six dogs had high body temperature. Their clinical signs were mostly episodic, and only non-specific symptoms were occasionally observed. Arthrocentesis was performed in all dogs, and immune-mediated polyarthritis (IMPA) was diagnosed. Definitive rheumatoid arthritis (RA) and systemic lupus erythematous (SLE) were diagnosed in one dogs, one each. Prednisolone (PDS) was chosen as the first-line therapy for all dogs, except for the one with RA. Most cases responded to PDS but some cases including those of SLE and RA were refractory to PDS. IMPA can be challenging to diagnose due to its vague symptom and is commonly implicated in 'fever of unknown origin'. Therefore, clinicians should consider IMPA as a differential diagnosis when the patient has fever with systemic, non-specific signs, such as anorexia and depression, but does not respond to antibiotics.

Cognitive Behavior Therapy in Trichotillomania (발모광 아동에서 인지행동치료)

  • Cho, Hwan-Il;Do, Jin-A;Kim, Yeon-Soo;Lim, Myung-Ho;Kim, Hyun-Woo
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제20권3호
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    • pp.158-164
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    • 2009
  • Trichotillomania is a neuropsychiatric disorder characterized by repetitive pulling out of one's hair. We present a trichotillomania case study illustrating the effectiveness of habit reversal training, which has recently been found, in western countries, to be a very effective cognitive behavioral treatment. The refractory patient in our study had previously received 1 year of drug treatment and psychiatric consultation for the disorder. We administered 10 habit reversal training sessions, which was followed by an obvious improvement in the patient's trichotillomania symptoms. Our observations indicate that habit reversal training might be effective in the treatment of trichotillomania.

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Endoscopic Treatment of Hypothalamic Hamartomas

  • Shim, Kyu Won;Park, Eun Kyung;Kim, Dong-Seok
    • Journal of Korean Neurosurgical Society
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    • 제60권3호
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    • pp.294-300
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    • 2017
  • Hypothalamic hamartoma (HH) is a benign indolent lesion despite the presentation of refractory epilepsy. Behavioral disturbances and endocrine problems are additional critical symptoms that arise along with HHs. Due to its nature of generating epileptiform discharge and spreading to cortical region, various management strategies have been proposed and combined. Surgical approaches with open craniotomy or endoscopy, stereotactic approaches with radiosurgery and gamma knife surgery or radiofrequency thermos-coagulation, and laser ablation have been introduced. Topographical dimension and the surgeon's preference are key factors for treatment modalities. Endoscopic disconnection has been one of the most favorable options performed in treating HHs. Here we discuss presurgical evaluation, patient selection, surgical procedures, and complications.

High Thoracic Epidural Analgesia for the Control of Pain in Unstable Angina Pectoris -A case report- (불안정형 협심증 환자의 고위 흉부 경막외 진통 효과 -증례보고-)

  • Lee, Bong Jae
    • The Korean Journal of Pain
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    • 제19권2호
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    • pp.271-274
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    • 2006
  • Unstable angina is a critical phase of coronary heart disease, with widely variable symptoms and prognoses. Recently, despite the advances in surgical revascularization, catheter-based revascularization and medical treatment, an increasing number of patients with angina pectoris are refractory to medical therapy and; therefore, can not be considered as candidates for coronary artery bypass grafting or interventional angioplasty. These patients are often treated with narcotics for pain relief, and forced to severely reduce their levels of activity and productivity. It has become clear that alleviating the pain caused by myocardial ischemia may be possible by altering the sympathetic afferent nerve fibers. Sympathetic blockade can be produced using high thoracic epidural analgesia. Herein, the case of a patient with intractable angina and poor ventricular function, who received high thoracic epidural analgesia to relieve ischemic chest pain, is reported.

Treatment of Os Trigonum Syndrome using Subtalar Arthroscopy (A Case Report) (거골하 관절경을 이용한 Os Trigonum Syndrome의 치료(1예 보고))

  • Ahn, Jae-Hoon;Baek, Chang-Hyun;Lee, Kwang-Won;Kim, Seung-Kwon;Choy, Won-Sik
    • Journal of Korean Foot and Ankle Society
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    • 제10권2호
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    • pp.267-270
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    • 2006
  • Os trigonum syndrome is a clinical disorder characterized by posterior ankle pain which occurs in excessive plantar flexion. The pain is elicited by the impingement of os trigonum between the calcaneus and the posterior edge of tibial plafond. Mostly, symptoms can be improved with nonsurgical management, however surgery is required for refractory cases. We report of a case of os trigonum syndrome in a female ballet dancer, which was successfully treated with subtalar arthroscopic excision of os trigonum.

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A Torticollis Case Managed by Balance Appliance of FCST for the Meridian and Neurologic Balance (FCST의 음양균형장치를 활용한 후천성 사경증 증례보고)

  • Yin, Chang-Shik;Koh, Gi-Wan;Sohn, Kyung-Seok;Lee, Jong-Jin;Sohn, Il-Hoon;Lee, Young-Jun
    • Korean Journal of Acupuncture
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    • 제23권1호
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    • pp.119-123
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    • 2006
  • Objectives : Therapeutic effect of Balance Appliance of functional cerebrospinal therapy (FCST) for meridian and neurologic yinyang balance was observed in a refractory torticollis case. Methods : A post-traumatic severe torticollis case with 18 years of duration was managed by the Balance Appliance on temporomandibular joint (TMJ), combined with acupuncture and manual medicine. Results : Assessment was made by self assessment of subjective symptoms and clinical observacon. The patient reported over-90% remission and returned to ordinary daily life after 20months of therapy, which effect was reported to maintain for 9 months. Conclusions : An impressive effect was observed and further clinical and biological research on FCST is expected.

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Mediastinal Bronchogenic Cyst Misdiagnosed as Asthma and Dysphagia in a Child - One Case Report - (소아에서 천식과 연하곤란으로 진단된 종격동 기관지 낭종 - 1예 보고 -)

  • Lee, Seock-Yeol;Jeon, Cheol-Woo;Lee, Seung-Jin;Lee, Cheol-Sae;Lee, Kihl-Rho
    • Advances in pediatric surgery
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    • 제14권1호
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    • pp.94-97
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    • 2008
  • A 19-month-old boy suffered from stridor and dysphagia. He was taking asthma medication for a few months, but symptoms did not improve. After admission, a chest CT showed a posterior mediastinal mass, which compressed the trachea and esophagus. The removed mass via open thoracotomy was a bronchogenic cyst on histopathology. Postoperatively, stridor and dysphagia disappeared. In case of persistent and refractory stridor or dysphagia in children, congenital lesions including bronchogenic cyst need to be ruled out.

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Immunosuppressive Therapy for Autoimmune Myasthenia Gravis (자가면역 중증근무력증의 면역억제요법)

  • Kim, Su-Yeon;Hong, Yoon-Ho
    • Annals of Clinical Neurophysiology
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    • 제9권2호
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    • pp.51-58
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    • 2007
  • Autoimmune myasthenia gravis (MG) is the neuromuscular junction disorder mostly caused by antibody against the acetylcholine receptor (AChR antibody) at the muscle endplate. The goal of treatment is to induce and maintain remission, i.e., absence of symptoms, with the least cost-to-benefit ratio. Although corticosteroids are effective in inducing remission in most patients, they have numerous potentially serious adverse effects with their long-term use. In addition, some patients do not respond or are intolerant to the conventional treatment. In this article, we discuss the difficulties encountered in long-term immunosuppressive treatment of MG, and review useful tips for the use of corticosteroids. Long-term immunosuppressive agents that can be used in steroid-refractory or -dependent patients will be reviewed with their safety profiles and efficacy in MG.

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Low-dose radiation therapy for massive chylous leakage after subtotal gastrectomy

  • Kim, Sang-Won;Kim, Jung Hoon
    • Radiation Oncology Journal
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    • 제35권4호
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    • pp.380-384
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    • 2017
  • Massive chylous leakage is a rare postoperative complication that can prolong hospital stay and cause secondary morbidities. Conservative management strategies are the treatment of choice; however, radiation therapy (RT) can be used as an alternative for cases that are refractory to conservative treatment. Herein, we report a 69-year-old female patient who suffered from massive chylous leakage after subtotal gastrectomy. Due to persistent massive chylous leakage, she was scheduled to undergo low-dose RT. Radiation was delivered with a daily dose of 1 Gy, using an anterior-posterior and posterior-anterior beam arrangement. The clinical target volume encompassed the entire lymph node area of the D2 dissection. RT was completed at the total dose of 8 Gy because the amount of chylous leakage declined rapidly. Percutaneous drainage tube was removed after 3 days of RT. The patient did not complain of any symptoms related to massive chylous leakage 2 years after the completion of RT.

Discal Cyst Diagnosed by Radiologic Finding

  • Lim, Hyung-Guhn;Kim, Hyeun-Sung;Kim, Seok-Won;Shin, Ho
    • Journal of Korean Neurosurgical Society
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    • 제41권6호
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    • pp.418-420
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    • 2007
  • Discal cyst is a very rare lesion that can result in refractory low back pain and leg radiating pain. Because they are so uncommon, their exact origin and pathophysiology are still unknown. A 31-year-old man visited our institute due to low back pain and severe left leg radiating pain. Magnetic resonance images [MRI] revealed spherically shaped extradural cystic lesion at L2-L3 level. Computed tomography [CT] discography demonstrated obvious communication between the intervertebral disc and the cyst. The patient underwent posterior decompression and excision of cyst. The symptoms were remarkably improved immediately after surgery.