• Title/Summary/Keyword: Reference standard

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A Study of Analytical Sensitivity on TDM Test Kit in Clinical Chemistry (약물검사 키트의 분석 민감도에 대한 연구)

  • Chang, Sang Wu;Kim, Nam Yong;Lee, Hee Gyung;Kim, Hyun Jung;Lee, Yun Jung;Jin, Ok Bae;Kim, Mi Gyung
    • Korean Journal of Clinical Laboratory Science
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    • v.36 no.2
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    • pp.127-130
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    • 2004
  • Analytical sensitivity on TDM test is the lowest concentration that can be distinguished from background noise. The aim of study was to evaluate analytical sensitivity that is also referred to as the lower limit of detection(LLD) about difference between zero calibrator and isotonic saline sample. We tested for 10 days with zero calibrators and 0.85% saline samples while running trilevel control samples under control. Raw data divided by two groups calculated mean and standard deviation from two sample populations and analytical sensitivity by ${\bar{X}}+2SD$. In comparison with isotonic saline samples and zero calibrators, there were significant differences in phenytoin, phenobarbital and vancomycin, etc. Especially analytical sensitivity on phenytoin is at the same level as the upper limit of analytical measurement range with $40{\mu}g/mL$. We think the cause of this is matrix interference. In conclusion, we were sure that standard protocol for analytical sensitivity as lower limit of analytical measurement range on TDM test must be measured with zero standard rather than an isotonic saline sample and type 1 reagent DW for reducing matrix effects within interactions between different materials in a mixture.

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ANALYSIS OF ASTRONOMICAL ALMANAC DATA FOR NATIONAL STANDARD REFERENCE DATA (참조표준 등록을 위한 천문역법 자료 분석)

  • Yang, Hong-Jin;Ahn, Young-Sook;Lee, Ki-Won
    • Publications of The Korean Astronomical Society
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    • v.23 no.2
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    • pp.53-63
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    • 2008
  • Korea Astronomy and Space Science Institute (KASI), direct decendant of Korea National Astronomy Observatory, has been publishing Korean Astronomical Almanac since in 1976. The almanac contains essential data in our daily lives such as the times of sunrise, sunset, moonrise, and moonset, conversion tables between luni-solar and solar calendars, and so forth. So, we are planning to register Korean astronomical almanac data for national Standard Reference Data(SRD), which is a scientific/technical data whose the reliablity and the accuracy are authorized by scientific analysis and evalution. To be certificated as national SRD, reference data has to satisfy several criteria such as traceability, consistency, uncertainty, and so on. Based on similarity among calculation processes, we classified astronomical almanac data into three groups: Class I, II, and III. We are planning to register them for national SRD in consecutive order. In this study, we analyzed Class I data which is aimed to register in 2009, and presented the results. Firstly, we found that the traceability and the consistency can be ensured by the usage of NASA/JPL DE405 ephemeris and by the comparsion with international data, respectively. To evaluate uncertainty in Class I data, we solved the mathematical model and determined the factors influencing the calculations. As a result, we found that the atmospheric refraction is the main factor and leads to a variation of ${\pm}16$ seconds in the times of sunrise and sunset. We also briefly review the histories of astronomical almanac data and of standard reference data in Korea.

Standard Implementation for Privacy Framework and Privacy Reference Architecture for Protecting Personally Identifiable Information

  • Shin, Yong-Nyuo
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.11 no.3
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    • pp.197-203
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    • 2011
  • Personal Identifiable Information (PII) is considered information that identifies or can be used to identify, contact, or locate a person to whom such information pertains or that is or might be linked to a natural person directly or indirectly. In order to recognize such data processed within information and communication technologies such as PII, it should be determined at which stage the information identifies, or can be associated with, an individual. For this, there has been ongoing research for privacy protection mechanism to protect PII, which now becomes one of hot issues in the International Standard as privacy framework and privacy reference architecture. Data processing flow models should be developed as an integral component of privacy risk assessments. Such diagrams are also the basis for categorizing PII. The data processing flow may not only show areas where the PII has a certain level of sensitivity or importance and, as a consequence, requires the implementation of stronger safeguarding measures. This paper propose a standard format for satisfying the ISO/IEC 29100 "Privacy Framework" and shows an implementation example for privacy reference architecture implementing privacy controls for the processing of PII in information and communication technology.

Nondestructive Prediction of Fatty Acid Composition in Sesame Seeds by Near Infrared Reflectance Spectroscopy

  • Kim, Kwan-Su;Park, Si-Hyung;Choung, Myoung-Gun;Kim, Sun-Lim
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.51 no.spc1
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    • pp.304-309
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    • 2006
  • Near infrared reflectance spectroscopy (NIRS) was used to develop a rapid and nondestructive method for the determination of fatty acid composition in sesame (Sesamum indicum L.) seed oil. A total of ninety-three samples of intact seeds were scanned in the reflectance mode of a scanning monochromator, and reference values for fatty acid composition were measured by gas-liquid chromatography. Calibration equations were developed using modified partial least square regression with internal cross validation (n=63). The equations obtained had low standard errors of cross-validation and moderate $R^2$ (coefficient of determination in calibration). Prediction of an external validation set (n=30) showed significant correlation between reference values and NIRS estimated values based on the SEP (standard error of prediction), $r^2$ (coefficient of determination in prediction) and the ratio of standard deviation (SD) of reference data to SEP. The models developed in this study had relatively higher values (more than 2.0) of SD/SEP(C) for oleic and linoleic acid, having good correlation between reference and NIRS estimate. The results indicated that NIRS, a nondestructive screening method could be used to rapidly determine fatty acid composition in sesame seeds in the breeding programs for high quality sesame oil.

Measurements of the rheological properties of standard reference material 2490 using an in-line micro-Fourier rheometer

  • Smith R. S.;Glasscock J. A.
    • Korea-Australia Rheology Journal
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    • v.16 no.4
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    • pp.169-173
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    • 2004
  • The control of the rheological properties of a fluid during processing is important and can determine the efficiency of the production in addition to the performance of the final product. The vast majority of process fluids are viscoelastic, hence an instrument that measures both the viscous and elastic properties of the material during processing would be of great practical use. However, most in-line instruments commercially available to date are only capable of measuring viscosity at a single shear rate. An in-line rheometer that measures both the viscous and elastic properties of fluids over a wide range of shear rates simultaneously has been described in a previous publication (Glasscock et at., 2003) in which the results of measurements on flowing sunflower oil were presented. Before this instrument can be used in an industrial situation, it must be demonstrated that the generated results are the same as, or bear some fixed relationship to, the results obtained by conventional off-line rheometers. To this end, the present investigation describes the measurements of a standard reference fluid, polyisobutylene dissolved in 2,6,10,14-tetramethylpentadecane, labelled SRM2490 by the National Institute of Standards and Technology (NIST) in the USA. The results obtained using the in-line rheometer show remarkably good correlation for viscosity, using a modified Cox­Merz rule, with the results supplied with the reference material from NIST.

A temperature sensor with low standard deviation with generating reference voltage for use in IoT applications (IoT 어플리케이션에서 활용하는 참조 전압을 같이 생성할 수 있는 표준 편차가 낮은 온도 센서)

  • Juwon Oh;Younggun Pu;Yeonjae Jung;Kangyoon Lee
    • Transactions on Semiconductor Engineering
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    • v.2 no.2
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    • pp.10-14
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    • 2024
  • This paper presents a circuit design aimed at generating the required reference voltage and temperature sensor voltage in conjunction with an ADC, utilizing the current generated by temperature characteristics of BJT components for sensor data conversion. Additionally, two control methods are introduced to reduce the standard deviation of the circuit, resulting in over a ten-fold decrease in standard deviation. The proposed circuit occupies an area of 0.057mm2 and was implemented using 55nm RF process.

Understanding of the WHO Standard Acupuncture Point Locations in the Western Pacific Region : General Guidelines (WHO/WPRO 표준 경혈 위치의 이해 : 일반기준을 중심으로)

  • Koo, Sung-Tae;Kim, Yong-Suk;Yim, Yun-Kyoung;Choi, Sun-Mi;Kang, Sung-Keel
    • Korean Journal of Acupuncture
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    • v.27 no.2
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    • pp.1-11
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    • 2010
  • Objectives : The aim of the study is to explain the general guidelines of the WHO standard acupuncture point locations (APLs). Understanding the general guidelines will enable experts to make the clear use of the standard APL for education, research and practice. Methods : In the beginning of development of the standard APL, experts made general guidelines to draw mutual agreements of the three nations (Korea, China, and Japan) on the standard APL. The guidelines include point locating methods, syntax of descriptive sentences, landmarks on body surface, reference acupuncture points, usage of anatomical terminology, and proportional bone measurements. Results : We found that there are some considerable problems in practical use of the APLs due to the strict application of anatomical terms, even on accessory phrases such as region of body in the sentence of each description. Conclusions : We hope that the study helps readers expand the understanding of the newly developed standard APLs resulting from increased application of acupuncture points. Also, it would be a reference to revise the WHO standard APLs in the future.

Estimation of Fluid Saturations Using Agarose Standard in NMR Imaging (자기 공명 영상법에서 Agarose 표준 물질을 사용한 유체 포화도의 계산)

  • Kim, Kyung-Hoe
    • Applied Chemistry for Engineering
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    • v.10 no.1
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    • pp.160-165
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    • 1999
  • Agarose gels can be used as reference standards for the measurement of fluid properties in porous media because the relaxation properties of the gel reference standard and those of the fluid in porous media can be closely matched. The use of reference standard to determine porosity and saturation is discussed and the requirements for gel NMR properties given. The relaxtion times of agarose gels measured at 2.0 Tesla are illustrated as a function of agarose and paramagnetic impurity ($CuSO_4$) concentrations. This work shows an empirical result between agarose gel composition and gel relaxtion times. The average value for the porosity distribution is 17.7%, which compares well with the value calculated with the gravimetric analysis. Finally, two phase immiscible displacement using agarose gels as a reference standard was performed. The saturation profiles appear to be consistent with what one might calculate for a one-dimensional displacement in a uniform porous media.

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Development of an Editor for Reference Data Library Based on ISO 15926 (ISO 15926 기반의 참조 데이터 라이브러리 편집기의 개발)

  • Jeon, Youngjun;Byon, Su-Jin;Mun, Duhwan
    • Korean Journal of Computational Design and Engineering
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    • v.19 no.4
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    • pp.390-401
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    • 2014
  • ISO 15926 is an international standard for integration of lifecycle data for process plants including oil and gas facilities. From the viewpoint of information modeling, ISO 15926 Parts 2 provides the general data model that is designed to be used in conjunction with reference data. Reference data are standard instances that represent classes, objects, properties, and templates common to a number of users, process plants, or both. ISO 15926 Parts 4 and 7 provide the initial set of classes, objects, properties and the initial set of templates, respectively. User-defined reference data specific to companies or organizations are defined by inheriting from the initial reference data and the initial set of templates. In order to support the extension of reference data and templates, an editor that provides creation, deletion and modification functions of user-defined reference data is needed. In this study, an editor for reference data based on ISO 15926 was developed. Sample reference data were encoded in OWL (web ontology language) according to the specification of ISO 15926 Part 8. iRINGTools and dot15926Editor were benchmarked for the design of GUI (graphical user interface). Reference data search, creation, modification, and deletion functions were implemented with XML (extensible markup language) DOM (document object model), and SPARQL (SPARQL protocol and RDF query language).

Implementation of Demo Program for Visual Communication in Compliance with MPEG-21 Part 22: User Description (MPEG-UD 표준을 준수하는 비쥬얼 커뮤니케이션 데모 프로그램 개발)

  • Lim, Hea-Jin;Choi, Jang-Sik;Jeon, Jin-Young;Byun, Hyung-Gi
    • Journal of Sensor Science and Technology
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    • v.25 no.4
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    • pp.297-301
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    • 2016
  • ISO/IEC JTC1/SC29WG11 MPEG has been standardizing UD(user description) to give a user personalized recommendation services. Besides, CD(context description), service description(SD), and recommendation description(RD) are recently being standardized by UD Adhoc Group in MPEG with an advanced UD to cope with needs of current and upcoming services such as augmented reality and social network. The descriptions was reflected to MPEG-UD WD(Working Draft) at MPEG $107^{th}$ meeting and the document was finally approved as international standard by national bodies with standard number(ISO/IEC IS 21000-22 UD) at $114^{th}$ MPEG meeting. In addition, reference software WD to validate conformance of UD standard was approved at $113^{th}$ MPEG meeting. In this paper, we developed a demo program for visual communication according to guideline defined in reference software WD to validate the reference software as well as UD standard.