• Speech Sciences
• /
• v.13 no.1
• /
• pp.55-66
• /
• 2006

A purpose of this study is to investigate the acoustic characteristics of English stress produced by the two groups of South Kyungsang (henceforth, SK) Korean speakers: high-proficiency and low-proficiency with reference to English native speakers. Another purpose is to compare results from the high- and low-proficiency SK Korean subjects with those of the native speakers, and to provide an analytical account of how approximate the high-proficiency SK Korean subjects' production is to the native speakers' and how different the low-proficiency SK Korean subjects' is from the native speakers'. Results indicated that the native speakers' main strategy used in producing stressed syllables was duration while the high-proficiency SK Korean subjects' was predominantly pitch-oriented. The low-proficiency SK Korean subjects' pitch patterns showed regularity, emphasizing the penultimate syllable with pitch. In comparing duration among the three groups, both groups of the SK Korean subjects became more even in their duration values for each syllable as the structure of the word or the sentence became more complex.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.32 no.4
• /
• pp.178-183
• /
• 2009

This study is designed to prove the role and effect of ethics codes in professional societies, especially for scientists and engineers working in R&D project groups. The hypotheses of influence on ethical conduct within the sample groups are tested and analyzed by statistical methods. Results show that the age of researchers and the integrity factor among the ethical conduct factors have significant influence on ethical conduct of research groups. The regression model of the ethical conduct factors also indicates a meaningful reference in an application or development of new ethics code in research organizations.

• Publications of The Korean Astronomical Society
• /
• v.23 no.2
• /
• pp.53-63
• /
• 2008

Korea Astronomy and Space Science Institute (KASI), direct decendant of Korea National Astronomy Observatory, has been publishing Korean Astronomical Almanac since in 1976. The almanac contains essential data in our daily lives such as the times of sunrise, sunset, moonrise, and moonset, conversion tables between luni-solar and solar calendars, and so forth. So, we are planning to register Korean astronomical almanac data for national Standard Reference Data(SRD), which is a scientific/technical data whose the reliablity and the accuracy are authorized by scientific analysis and evalution. To be certificated as national SRD, reference data has to satisfy several criteria such as traceability, consistency, uncertainty, and so on. Based on similarity among calculation processes, we classified astronomical almanac data into three groups: Class I, II, and III. We are planning to register them for national SRD in consecutive order. In this study, we analyzed Class I data which is aimed to register in 2009, and presented the results. Firstly, we found that the traceability and the consistency can be ensured by the usage of NASA/JPL DE405 ephemeris and by the comparsion with international data, respectively. To evaluate uncertainty in Class I data, we solved the mathematical model and determined the factors influencing the calculations. As a result, we found that the atmospheric refraction is the main factor and leads to a variation of ${\pm}16$ seconds in the times of sunrise and sunset. We also briefly review the histories of astronomical almanac data and of standard reference data in Korea.

• Biomolecules & Therapeutics
• /
• v.16 no.3
• /
• pp.255-260
• /
• 2008

The purpose of this study was to evaluate the bioequivalence of the test (Daewoo Hydrocortisone 10 mg, Daewoo Pharm. Co., Busan, Korea) and reference (Jenapharm Hydrocortisone 10 mg, JayTech Biogen, Seoul, Korea) hydrocortisone tablets. Twenty-four healthy male Korean volunteers were divided into two groups with a randomized $2{\times}2$ cross-over design. In order to suppress the endogenous cortisol secretion, a single oral dose of Dexamethasone (4 mg) was administered 10 hr prior to hydrocortisone administration. Blood samples were withdrawn for 10 hr at the predetermined intervals after a single oral dose of hydrocortisone (20 mg). The serum concentration of hydrocortisone was analyzed by HPLC/UV using a column switching method after liquid-liquid extraction process. The pharmacokinetic parameters ($AUC_{0{\sim}10hr}$, $C_{max}$, and $T_{max}$) of the test and reference hydrocortisone tablets were determined while the secretion of endogenous cortisol was being suppressed. The pharmacokinetic parameters of the test tablet were not statistically different from those of the reference tablet at ex value was 0.05. The 90% confidence intervals for the average ratio (test/reference) of $AUC_{0{\sim}10hr}$ and $C_{max}$ were within the Korea Food and Drug Administration acceptance range of 0.80-1.25 ($0.89{\sim}0.99$ and $0.86{\sim}0.99$ for $AUC_{0{\sim}10hr}$ and $C_{max}$, respectively). Therefore it was concluded that the test tablet, Daewoo Hydrocortisone tablet was bioequivalent to the reference tablet, Jenapharm Hydrocortisone tablet.

• Biomolecules & Therapeutics
• /
• v.15 no.2
• /
• pp.118-122
• /
• 2007

This study was performed to evaluate the bioequivalency between the Osmetone$^{TM}$ Tablet (Myeongmoon Pharm. Co., Ltd.) as a test formulation and the Relafen$^{TM}$ Tablet (Handok Pharm. Co., Ltd.) as a reference formulation. Twenty-four healthy male volunteers were administered the formulations by the randomized Latin square crossover design, and the plasma samples were determined by a high performance liquid chromatography (HPLC) with Ultra-Violet (UV) detector. AUC$_t$, C$_{max}$ and T$_{max}$ were obtained from the time-plasma concentration curves, and log-transformed AUC$_t$ and C$_{max}$ and log-untransformed T$_{max}$ values for two formulations were compared by statistical tests and analysis of variation. AUC$_t$ was determined to be 897.8${\pm}$431.1 ug.hr/ml for the reference formulation and 902.3${\pm}$408.4 ug.hr/ml for the test formulation. The mean values of C$_{max}$ for the reference and test formulations were 24.2${\pm}$8.9 and 24.0${\pm}$9.5 ug/ml, respectively. The AUC$_t$ and C$_{max}$ ratios of the reference Relafen$^{TM}$ Tablet to the test Osmetone$^{TM}$ Tablet were +5.01% and -0.83%, respectively, showing that the mean differences were satisfied the acceptance criteria within 20%. The results from analysis of variance for logtransformed AUC$_t$ and C$_{max}$ indicated that sequence effects between groups were not exerted and 90% confidence limits of the mean differences for AUC$_t$ and C$_{max}$ were located in ranges from log 0.80 to log 1.25, satisfying the acceptance criteria of the KFDA bioequivalence. The Osmetone$^{TM}$ Tablet as the test formulation was considered to be bioequivalant to the Relafen$^{TM}$ Tablet used as its reference formulation, based on AUC$_t$ and C$_{max}$ values.

• Biomolecules & Therapeutics
• /
• v.14 no.1
• /
• pp.50-55
• /
• 2006

The objective of the study was to evaluate the bioequivalency between the $Rozid^{TM}$ Tablet (Ilhwa Pharm. Co., Ltd.) as a test formulation and the $Rulid^{TM}$ Tablet (Handok Pharm. Co., Ltd) as a reference formulation. Twenty-four healthy male volunteers were administered the formulations by the randomized Latin square crossover design, and the plasma samples were determined by a high performance liquid chromatography (HPLC) with fluorescence detector. $AUC_t,\;C_{max}\;and\;T_{max}$ were obtained from the time-plasma concentration curves, and log-transformed $AUC_t\;and\;C_{max}$ and log-untransformed $T_{max}$ values for two formulations were compared by statistical tests and analysis of variation. $AUC_t$ was determined to be $63.30{\pm}25.57{\mu}g.hr/ml$ for the test formulation and $64.02{\pm}29.27mg.hr/ml$ for the reference formulation. The mean values of $C_{max}$ for the test and reference formulations were $5.07{\pm}2.14\;and\;5.53{\pm}2.60{\mu}g/ml$, respectively. The $AUC_t,\;and\;C_{max}$ ratios of the test $Rozid^{TM}$ Tablet to the reference $Rulid^{TM}$ Tablet were -1.12% and -8.32%, respectively, showing that the mean differences were satisfied the acceptance criteria within 20%. The results from analysis of variance for log-transformed $AUC_t,\;and\;C_{max}$ indicated that sequence effects between groups were not exerted and 90% confidence limits of the mean differences for $AUC_t,\;and\;C_{max}$ were located in ranges from log 0.80 and log 1.25, satisfying the acceptance criteria of the KFDA bioequivalence. The RozidTM Tablet as the test formulation was considered to be bioequivalent to the RulidTM Tablet used as its reference formulation, based on $AUC_t,\;and\;C_{max}$ values.

• The Korean Journal of Nuclear Medicine Technology
• /
• v.27 no.1
• /
• pp.42-46
• /
• 2023

Purpose The reference range described in Adrenocorticotropic Hormone reagent used in our laboratory is 10-60 pg/mL at 8 a.m. to 10 a.m., and 6-30 pg/mL at 8 p.m. to 10 p.m. However, in the case of outpatients, blood is mainly collected between 10 a.m. and 6 p.m., accounting for 57.8% of the total. Therefore, This study is intended to help make a more accurate diagnosis by reevaluating the reference range provided by the manufacturer of the Adrenocorticotropic Hormone reagent and setting split-timed reference range. Materials and Methods The patients collected blood before 10 a.m. were group A (68 people), and the patients collected blood after 10 a.m. were set to group B (80 people). A T-test was performed between groups to test their significance. And it was confirmed whether it was necessary to set the gender classification as a subgroup. The method of setting the reference range was calculated by the Bayesian's method and the Hoffmann's method. Results The reference range of Group A was 8.6 to 60.6 pg/mL by the Bayesian's method, and the Hoffmann's method was 3.6 to 61.3 pg/mL. The reference range of Group B was 6.9 to 50.5 pg/mL when applying the Bayesian's method, and the Hoffmann method's was 2.3 to 48.9 pg/mL. Conclusion This study was concluded that it was necessary to set the split-timed reference range. Through this study, the later the blood collection time, the lower the level of Adrenocorticotropic Hormone, indicating that blood collection time is important for patients with clinical significance. If a large number of subjects are selected and supplemented in the future, it is believed that systematic and accurate reference range can be set.

• Phonetics and Speech Sciences
• /
• v.4 no.4
• /
• pp.117-127
• /
• 2012

This research reports the prosodic characteristics (including articulation speech rate, pause characteristics, duration) of children with cochlear implants with reference to those of children with normal hearing. Subjects are 8-to 10-year-old children, balancing each number of gender as 24. Dialogue speech data are comprised of four types of sentence patterns. Results show that 1) there's a statistically meaningful difference on articulation speech rate between the two groups. 2) On pauses, they are not observed in exclamatory and declarative sentences in normal children. While imperative sentences show no statistical difference on the number of pauses between the two groups, interrogative sentences do. 3) Declarative, exclamatory, and interrogative sentences reveal statistical difference between the two groups in terms of the sentence's final two-syllable word duration, showing no difference on imperative sentences. 4) When it comes to the RFP (duration ratio of sentence final syllable to penultimate syllable), we no statistically meaningful difference between the two groups in all types of sentences exists. 5) Lastly, RWS (the ratio of sentence final two syllable word duration to that of whole sentence duration) shows statistical difference between two groups in imperative sentences, but not in all the rest types.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.30 no.4 s.152
• /
• pp.542-553
• /
• 2006

The purpose of this study were to analyse of craniofacial shape by 3D and to develope of head models for Korean adults with gender and age groups. The 3D measurement technique adapted in this study was a novel approach compared that the same technique has been commonly used in measuring human bodies. The data and the model of head analysis can be used as a basic reference in developing various head related items such as hat, helmet, gas mask, ear phone, and etc. In this study, heads of 836 Korean adults were measured in 3D, analyzed by statistical methods, and modelized in 3D by gender and age groups. From the basic statistical data analysis, vertex-tragion and the length between the pupils were the longest in their twenties for both men and women, and grew shorter in elderly groups. In all categories, a significant difference appeared between men and women in their 20's, but the differences were less noticeable in elderly groups. Compared to the one size standard head model of the Korea Occupational Safety and Health Agency, the above three-dimensional standard head model would provide a more through fit because gender and age groups were sub-divided and analyzed in 3D.

• Journal of the Korean Society for Library and Information Science
• /
• v.17
• /
• pp.261-273
• /
• 1989

The study attempted to determine if the effectiveness of bibliographic 'instruction would be different among student groups, divided by grade levels, major areas of study, and the level of library skills posessed before the instruction. The focal point of the investigation was the degree of improvement demonstrated by the changes in mean score of each group after taking bibliographic instruction. Sangmyong Women's University students who have taken the bibliographic instruction course for credit were the subjects of the study. Students' library skills were measured prior to the bibliographic instruction and post-test was followed. And the measured was based on the 'Library skills Test' developed by the Illinois Association of College and Research Libraries. Three hypotheses in the study were tested statistically by ANOVA. The followings are the results of the analysis: (1) There were no significant differences in bibliographic instruction effectiveness among student groups divided by grade levels; (2) There were significant differences (p<.01) in bibliographic instruction effectiveness among student groups divided by major areas of study. Bibliographic instruction was more effective for humanities or social sciences majors than for performing arts or physical education majors; (3) There were significant differences (p<.001) in bibliographic instruction effectiveness among student groups divided by the initial library skills. Obviously, bibliographic instruction was more effective for the students in bottom quartile than those in top quartile or middle quartiles. Finally, limitations of the study, recommendations based on the results and area for future research are briefly examined.