• Title/Summary/Keyword: Recommended Weight Limit

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Concentrations of N,N-dimethylformamide in Polyurethane Gloves and Risk Assessment for Dermal Exposures (폴리우레탄 코팅장갑내의 DMF 함량 및 피부노출에 대한 평가)

  • Park, Hae Dong;Ro, Jiwon
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.32 no.2
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    • pp.102-110
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    • 2022
  • Objectives: The purpose of this study is to analyze the content of N,N-dimethylformamide(DMF) in polyurethane coated gloves(PU-gloves) and to assess the dermal exposure generated by wearing them. Methods: We analyzed the concentrations of DMF in 12 gloves by EN16778 standard. The samples cut into pieces of about 10 by 10 mm and extracted with methanol in flask in an ultrasonic bath at 70℃. An aliquot of the extract is analyzed with GC-MS. The dose of dermal exposure was calculated by ECETOC TRA consumer 3.1 and compared with derived no effect level(DNEL) for systemic effects due to long term exposure by workers. The extracted amount of DMF by saline solution was compared with that by EN16778 standard. Results: The mean concentration of DMF in PU-gloves was 1,377 mg/kg(range 13~3,948 mg/kg). The concentration of DMF showed significantly differences by packing type, manufacturer, and price(p<0.05). The dose of dermal exposure was 0.0007~0.572 mg/kg body weight/day when the DMF content was 10~4,000 mg/kg. The DMF extracted by saline solution was around 11% for 8 hours. Conclusions: The risk of dermal exposure due to the residual DMF in the PU-gloves was not signifiant. But, the limit of 1,000 mg/kg in PU-gloves can be recommended for international standard and trading systems.

Comparison of Three Methods Assessing the Ergonomic Risks of Manual Lifting Tasks at Ship Engine Manufacturing Facilities (선박용 엔진 제조업 들기작업의 인간공학적 위험 평가를 위한 세 가지 방법 비교)

  • Kim, Sun Ja;Shin, Yong Chul;Kim, Boo Wook;Kim, Hyun Dong;Woo, Ji Hoon;Kang, Dongmug;Lee, Hyun Seok
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.15 no.2
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    • pp.104-113
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    • 2005
  • A variety of ergonomic assessment methods of lifting tasks known as a major cause of work-related lower back pain have been used. But there is a limited information in choosing the most appropriate assessment method for a particular job and in finding out strengths and weakness of the methods. The purpose of this study was to assess and compare the ergonomic risks of lifting tasks in a marine diesel engine production industry by three lifting ergonomic assessment tools widely used: the National Institute for Occupational Safety and Health(NIOSH) Revised Lifting Equation(NLE), the Washington Administrative Code 296-62-0517(WAC), and the Snook Tables. Lifting index(weight of load/Recommended Weight Limit) of NLE($LI_{NLE}$) was above 1 at 34 tasks(75.6%) of a total number of 45 lifting tasks. LI of WAC($LI_{WAC}$) was above 1 at 11 tasks(24.4 %). LI of Snook Table($LI_{Snook}$) was above 1 at 29 tasks(64.4%). Thus, LI was high in orders of $LI_{NLE}$ > $LI_{Snook}$ > $LI_{WAC}$. There were significantly high correlations among three Lls(p<0.01). The correlation coefficients between $LI_{NLE}$and the other three Lls($LI_{WAC}$ and $LI_{Snook}$) were r=0.93 and r=0.88, respectively. The linear regression equations were y = 0.444x + 0.11(r=0.93) between $LI_{NLE}$ and $LI_{WAC}$, y = 0.93x + 0.008(r=0.88) between LI(NLE) and $LI_{Snook}$. The LI values by WAC was significantly lower than those by the other tools. The compared features, strength and limitation among these tools were described in this paper.

Survey on the changes of sulfamethazine residues in serum, liver and muscle according to the time lapsed after oral administration of sulfamethazine sodium to rats using HPLC (Rat에 sulfamethazine sodium 경구투여 후 시간경과에 따른 혈청, 간장 및 근육내 잔류함유량 변화)

  • 도재철;장지택;이영미;조종숙;조민희;박희주;신대길
    • Korean Journal of Veterinary Service
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    • v.23 no.2
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    • pp.143-152
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    • 2000
  • Sulfamethazine sodium was orally administrated to sprague-dawley strain male rats(body weight, 200-300g) with using sonde at the rate of 20 mg/100g body weight(recommended therapeutic dose) on once a day for 3 days. There were investigated the depletion rate of the sulfamethazine in serum, liver and skeletal muscle of rat at the time 8 hours, 1st, 2nd, 3rd, 4th, 5th and 6th day after administration sulfamethazine sodium. 1. The mean concentrations of sulfamethazine in serum according to the time lapsed after oral administration of the sulfamethazine soudijm were showed 215.53$\pm$42.99 ppm at the 8 hours after withdrawal of medicated sulfamethazine. And gradually according to the time lapsed, the concentrations of sulfamethazine residues in serum were significantly (p<.05) decreased 25.87$\pm$5.18 ppm at 1st day, 2.30$\pm$0.61 ppm at 3rd day and 0.11$\pm$0.02 ppm at 6th day after withdrawal of medicated sulfamethazine. 2. The mean concentrations of sulfamethazine in liver were significantly (p<.05) decreased 81.77 $\pm$ 12.88 ppm to 0.11$\pm$0.03 ppm between 8 hours and 6th day according to the time lapsed after oral administration of the sulfamethazine sodium for 3 days. 3. After oral administration of the sulfamethazine sodium, the mean concentrations of sulfamethazine in skeletal muscle were significantly (p<.05) decreased 35.96$\pm$1.39 ppm to 0.009$\pm$0.001 ppm between 8 hours and 6th day after withdrawal of medicated sulfamethazine. At the 4th day, the concentrations of sulfamethazine residues were showed 0.10 $\pm$ 0.04 ppm below 0.1 ppm at the permitted limit concentration of muscle in Korea. 4. After oral administration of the sulfamethazine sodium once a day for 3 days, there were showed the highest concentration in serum (215.53$\pm$42.99 ppm) than in liver(81.77$\pm$12.88 ppm) and skeletal muscle (35.96$\pm$1.39 ppm) at the 8 hours after withdrawal of medicated sulfamethazine. The mean concentration of sulfamethazine residues in serum, liver and skeletal muscle were gradually decreased according to the time lapsed.

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Hepatic Protective Effect and Single-dose Toxicity Study of Water Extract of Cordyceps militaris Grown upon Protaetia dreujtarsis (굼벵이 유래 밀리타리스 동충하초 열수추출물의 간기능개선 효과 및 단회독성 평가)

  • Jo, Wol-Soon;Nam, Byung-Hyouk;Oh, Su-Jung;Choi, Yoo-Jin;Kang, Eun-Young;Hong, Sook-Hee;Lee, Sang-Ho;Jeong, Min-Ho
    • Korean Journal of Food Science and Technology
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    • v.40 no.1
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    • pp.106-110
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    • 2008
  • This study was designed to evaluate the single dose toxicity and the protective effect of water extract of Cordyceps militaris grown upon Protaetia dreujtarsis (CMPD extract) on liver damage on carbon tetrachloride ($CCl_4$)- induced acute hepatotoxicity in Sprague-Dawley (SD) rats. The CMPD extract was once administered orally to both sexes of rats at dose of 2,000, 1,000 and 500 mg/kg body weight, the recommended maximum limit dose for acute toxicity. Neither significant toxic signs nor death was observed during the observation period. These results indicate that $LD_{50}$(lethal dose of 50%) of CMPD extract is greater than 2,000 mg/kg body weight in SD rats. To investigate also the effect of hepatoprotection of CMPD extract, SD rats were orally treated with CMPD extract (50, 25 and 12.5 mg/kg body weight) or silymarin (25 mg/kg body weight) before and after administration of $CCl_4$ (2 mL/kg body weight, 20% $CCl_4$ in olive oil). Treatment with CMPD extract or silymarin could decrease the GPT (glutamic-pyruvic transaminase) and GOT (glutamic-oxaloacetic transaminase) levels in serum when compared with $CCl_4$-treated group. Therefore, the results of this study show that CMPD extract can be proposed to protect the liver against $CCl_4$-induced hepatic damage in rats.

The Ontology Based, the Movie Contents Recommendation Scheme, Using Relations of Movie Metadata (온톨로지 기반 영화 메타데이터간 연관성을 활용한 영화 추천 기법)

  • Kim, Jaeyoung;Lee, Seok-Won
    • Journal of Intelligence and Information Systems
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    • v.19 no.3
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    • pp.25-44
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    • 2013
  • Accessing movie contents has become easier and increased with the advent of smart TV, IPTV and web services that are able to be used to search and watch movies. In this situation, there are increasing search for preference movie contents of users. However, since the amount of provided movie contents is too large, the user needs more effort and time for searching the movie contents. Hence, there are a lot of researches for recommendations of personalized item through analysis and clustering of the user preferences and user profiles. In this study, we propose recommendation system which uses ontology based knowledge base. Our ontology can represent not only relations between metadata of movies but also relations between metadata and profile of user. The relation of each metadata can show similarity between movies. In order to build, the knowledge base our ontology model is considered two aspects which are the movie metadata model and the user model. On the part of build the movie metadata model based on ontology, we decide main metadata that are genre, actor/actress, keywords and synopsis. Those affect that users choose the interested movie. And there are demographic information of user and relation between user and movie metadata in user model. In our model, movie ontology model consists of seven concepts (Movie, Genre, Keywords, Synopsis Keywords, Character, and Person), eight attributes (title, rating, limit, description, character name, character description, person job, person name) and ten relations between concepts. For our knowledge base, we input individual data of 14,374 movies for each concept in contents ontology model. This movie metadata knowledge base is used to search the movie that is related to interesting metadata of user. And it can search the similar movie through relations between concepts. We also propose the architecture for movie recommendation. The proposed architecture consists of four components. The first component search candidate movies based the demographic information of the user. In this component, we decide the group of users according to demographic information to recommend the movie for each group and define the rule to decide the group of users. We generate the query that be used to search the candidate movie for recommendation in this component. The second component search candidate movies based user preference. When users choose the movie, users consider metadata such as genre, actor/actress, synopsis, keywords. Users input their preference and then in this component, system search the movie based on users preferences. The proposed system can search the similar movie through relation between concepts, unlike existing movie recommendation systems. Each metadata of recommended candidate movies have weight that will be used for deciding recommendation order. The third component the merges results of first component and second component. In this step, we calculate the weight of movies using the weight value of metadata for each movie. Then we sort movies order by the weight value. The fourth component analyzes result of third component, and then it decides level of the contribution of metadata. And we apply contribution weight to metadata. Finally, we use the result of this step as recommendation for users. We test the usability of the proposed scheme by using web application. We implement that web application for experimental process by using JSP, Java Script and prot$\acute{e}$g$\acute{e}$ API. In our experiment, we collect results of 20 men and woman, ranging in age from 20 to 29. And we use 7,418 movies with rating that is not fewer than 7.0. In order to experiment, we provide Top-5, Top-10 and Top-20 recommended movies to user, and then users choose interested movies. The result of experiment is that average number of to choose interested movie are 2.1 in Top-5, 3.35 in Top-10, 6.35 in Top-20. It is better than results that are yielded by for each metadata.

Study on the Chemical Management - 1. Chemical Characteristics and Occupational Exposure Limits under Occupational Safety and Health Act of Korea (화학물질 관리 연구-1. 산업안전보건법상 관리 화학물질의 특성과 노출기준 비교)

  • Park, Jihoon;Ham, Seunghon;Kim, Sunju;Lee, Kwonseob;Ha, Kwonchul;Park, Donguk;Yoon, Chungsik
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.25 no.1
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    • pp.45-57
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    • 2015
  • Objectives: This study aims to compare the physicochemical characteristics, toxicological data with Occupational Exposure Limits (OELs) of chemicals under the Occupational Safety and Health Act(OSHA) regulated by the Ministry of Employment and Labor of Korea. Methods: Information on chemicals which have OELs on physicochemical characteristics and toxicological data was collected using Material Safety Data Sheet(MSDS) from Korea Occupational Safety and Health Agency(KOSHA) and the Korea Information System for Chemical Safety Management(KISChem) in 2014. Statistical analyses including correlation and simple regression were performed to compare the OELs with chemical characteristics including molecular weight, boiling point, odor threshold, vapor pressure, vapor density, solubility and octanol-water partition coefficient(OWPC) and toxicological data such as median lethal dose($LD_{50}$) and median lethal concentration($LC_{50}$). Results: A total of 656 chemicals have OELs under OSHA in Korea. The numbers of chemicals which have eight-hour time weighted average(TWA) and short term exposure limits(STEL) are 618 and 190, respectively. TWA was significantly correlated with boiling point and STEL was only correlated with vapor pressure among physicochemical characteristics. Solubility and OWPC between "skin" and "no skin" substances which indicate skin penetration were not significantly different. Both $LD_{50}$ and $LC_{50}$ were correlated with TWA, while the $LC_{50}$ was not with STEL. As health indicators, health rating and Emergency Response Planning Guidelines(ERPG) rating as recommended by the National Fire Protection Association(NFPA) and American Industrial Hygiene Association(AIHA) were associated with OELs and reflect the chemical hazards. Conclusions: We found relationships between OEL and chemical information including physicochemical characteristics and toxicological data. The study has an important meaning for understanding present regulatory OELs.

Minimum Design Thickness of Prestressed Concrete Deck Slabs for Composite Two-Girder Bridges (강합성 2거더교 프리스트레스트 바닥판의 설계 최소두께)

  • Hwang, Hoon Hee;Joh, Changbin;Kwark, Jong Won;Lee, Yong Woo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.1A
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    • pp.183-190
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    • 2006
  • Minimizing the self weight of long-span deck slabs is one of the key factors for the practical and economic design of a composite two-girder bridge. In this paper, the minimum design thickness and rebar details of prestressed concrete deck slabs for composite two-girder bridges with girder span length from 4 m to 12 m are studied based on the safety and serviceability. The bridge deck slab with minimum thickness is designed as a one-way slab considering orthotropic behavior. Then fatigue safety of the deck slab is examined. Serviceability requirements for the deck slab such as deflection and crack width limits are also examined. The result shows that rebars with diameter less than 16 mm is recommended for the improved fatigue behavior, and, for the deck slab with span length longer than 8 m, the deflection limit governs the minimum design thickness. The result also shows that, for the deck slab with span length longer than 4 m, the distribution rebar requirement in the current Korea Highway Bridge Design Code is not sufficient to maintain the structural continuity in bridge axis as expected from the deck slab with span length shorter than 3 m.

Forest Soil Characteristics and their Effects on the Trafficability of Logging Vehicles (산림토양(山林土壤) 특성(特性)이 집재차량(集材車輛)의 주행성(走行性)에 미치는 영향(影響))

  • Kim, Ki Weon
    • Journal of Korean Society of Forest Science
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    • v.88 no.2
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    • pp.255-265
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    • 1999
  • This study deals with forest soil characteristics and their effects on the trafficability of logging vehicles. The study area is the national experimental forest located in Kwangnung. This site has 20m length and is equally divided by 5 surveying ranges with 4m width, on which a tractor(FIATAGRI) attached with logging boogie can drive in 4 driving types, namely 1time-return unload, 1time-return with load of 780-790kg weight of 3 logs, 5 and 10times-return with same load. After one driving type on all surveying ranges, the soil hardness is surveyed 5 times with 3 several type tools, SHM-1 type, lang penetrometer(L-PNTM), and clegg impact soil tester(CIST). A disturbed degree of cover vegetation and sliding conditions of vehicle are also observed. As results, the soil type of the test site was SC by USCS and dry brown forest soil. The cover vegetation is gotten trambled under driving after 3-5 times-return, shrubs leaves are fully fallen and their bark are peeled, and after 10 times-return the cover vegetations were nearly disappeared. The test vehicle has neither slided nor was overthrown. The wheel tracks in the 1-3 ranges, of which unit weight(gd, gt) is high and soil moisture content(MC) is low, were only 1-2cm deep, but those in the 4-5 ranges, of which the gd, gt is low and the MC is high, were 5-7cm deep. In the soil hardness test, which was established in 5 test ranges by types of driving, the more driving times, the higher the hardness. The soil hardness surveyed by L-PNTM has changed slowly and that surveyed by SHM-1 type has risen sharply. In the ranges with higher specific gravity(Gs), higher unit weight, lower MC and higher liquid limit(LL) and plasticity index(PI) was the soil hardness high and the trafficability was good. In the ranges with opposite conditions, also in the ranges of the lower soil hardness, the trafficability must be not good, because the wheel track may be deep. The results from CIST attached with 4kg hammer was not better than expected. So it is recommended to use CIST with 2.5kg or 0.5kg hammer.

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Estimation of Optimum Application Rate of Nitrogen Fertilizer Based on Soil Nitrate Concentration for Tomato Cultivation in Plastic Film House (토양의 질산태 질소 검정에 의한 시설재배 방울토마토의 질소 적정시비량 추정)

  • Kang, Seong-Soo;Hong, Soon-Dal
    • Korean Journal of Soil Science and Fertilizer
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    • v.37 no.2
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    • pp.74-82
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    • 2004
  • This study was conducted to estimate the optimum application rate of fertilizer N based on $NO_3-N$ concentration in soils for tomato (Lycopersicon esculentum Mill.) cultivation in plastic film house. Tomato plants were cultivated with and without fertilizer in twelve soils which have different concentrations of $NO_3-N$ ranging from 46 to $344mg\;kg^{-1}$. Dry weight (DW) of above-ground part of tomato with no fertilizer ranged from 28.9 to $112.5g\;plant^{-1}$, depending on N-supplying capability of soils. The soil $NO_3-N$ was positively correlated with DW ($r=0.83^{**}$) and N uptake ($r=0.78^{**}$) by tomatoes in no fertilizer treatment, and negatively correlated with fertilizer effciencies resulted from the differences of DW and N uptake between fertilized and non-fertilized plot. The relationships between soil $NO_3-N$ concentration and DW, N uptake, and fertilizer efficiency were analyzed to determine the critical levels of soil $NO_3-N$ for tomato cultivation. The limit critical levels of soil $NO_3-N$ were estimated to be more than $280mg\;kg^{-1}$ for no application of fertilizer N and to be less than $50mg\;kg^{-1}$ for recommended application of fertilizer N. These critical levels of soil $NO_3-N$ were nearly the same as those calculated from regression equation between electrical conductivity(EC) and soil nitrate for critical levels of EC in recommendation equation of fertilizer N for tomato under the plastic film house by NationaI Institute of Agricultural Science and Technology. Consequently, the optimal application rate of ferdilizer N for tomato cultivation in the soils containing $NO_3-N$ concentration between $280mg\;kg^{-1}$ and $50mg\;kg^{-1}$ was estimated by the equation Y = -0.4348X+121.74, where Y is the percent(%) to the recommended application rate of N fertilizer and X is the soil $NO_3-N$ concentration ($mg\;kg^{-1}$).

Study on the changes of sulfamethnzine residues in serum and practical organs of rats orally administrated with sulfamethnzine sodium (Rat에 sulfamethazine sodium 경구투여 후 혈청 및 실질장기내 sulfamethazine의 잔류량 추이에 관한 연구)

  • 도재철;이영미;조민희;신상희;박희주;송희종;정종식
    • Korean Journal of Veterinary Service
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    • v.23 no.4
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    • pp.321-333
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    • 2000
  • In order to know the depletive changes of sulfamethazine residues in senlm and practical organs of rats orally administered with sulfamethazine sodium(SMS), the concentration of sulfamethazine was measured in serum and tissue(kidney, liver, spleen, testis, and skeletal muscle) of rats with using high performance liquid chromatography(HPLC). SMS was orally administrated to sprague-dawley male rats(body weight, 200~300g) with using sonde at the rate of 20mg/100g body weight(recommended therapeutic dose) on once a day for 3 days. There were investigated the depletive changes of the sulfamethazine in serum, kidney, liver, spleen, testis and skeletal muscle of rat at the time 8 hours, 1st, 2nd, 3rd, 4th, 5th and 6th day after administration SMS, respectively. The results obtained were summarized as follows; 1. After oral administration of the SMS, the mean concentrations of sulfamethazine in serum according to the time lapsed were showed 215.53$\pm$42.99ppm at the 8 hours after withdrawal of medicated sulfamethazine. And gradually according to the time lapsed, the concentrations of sulfamethazine residues in serum were significantly (p<.05) decreased 25.87$\pm$5.18ppm at 1st day, 2.30$\pm$0.61ppm at 3rd day and 0.11$\pm$0.02ppm at 6th day respectively. 2. The mean concentrations of sulfamethazine in kidney, liver, spleen, muscle and testis according to the time lapsed after administration SMS were showed 83.82$\pm$12.16, 81.77$\pm$12.88, 36.96$\pm$5.35, 35.96$\pm$TEX>$\pm$1.39 and 27.89$\pm$1.92 ppm at the 8 hours, respectively. And gradually according to the time lapsed, the concentrations of sulfamethazine residues in the each of samples were significantly(p<.05) decreased such as 7.15$\pm$0.26, 5.62$\pm$0.72, 2.43$\pm$0.29, 1.99$\pm$0.14 and 3.11$\pm$0.48 ppm at 1st day, 0.52$\pm$0.04, 1.32$\pm$0.22, 0.13$\pm$0.03, 0.15$\pm$0.06 and 0.26$\pm$0.11ppm at 3rd day, and 0.03$\pm$0.01, 0.11$\pm$0.03, 0.02$\pm$0.01, 0.009$\pm$0.001 and 0.02$\pm$0.01 ppm at 6th day, respectively. 3. After oral administration of the SMS to rats, the residual concentrations of sulfamethazine in skeletal muscle were significantly (p<.05) decreased 35.96$\pm$1.39 to 0.009$\pm$$\pm$0.001 ppm between 8 hours and 6th day, respectively From the 4th day, the residual concentrations of sulfamethazine were showed 0.10$\pm$0.04 ppm below 0.1 ppm at the permitted limit concentration of muscle in Korea. In conclusion, this study could be suggested the relationship between administrated period, doses of sulfonamides and residual aspects of serum and practical organs, and the importance of observing ceasing period of antibiotic drugs before forwarding livestocks to slaughter.

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