• Preventive Nutrition and Food Science
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• 제8권2호
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• pp.191-195
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• 2003

We investigated the effects of gamma irradiation on the microbiological, chemical and sensory qualities of bulgogi, a traditional Korean meat product. Gamma irradiation reduced the number of coliform bacteria and bacterial colonies counted in Salmonella-Shigella selective agar to a non-detectable level. Thermophillic microorganisms (mainly Bacillus spp.) in bolgogi refrigerated for 20 days were also significantly reduced by 3 log cycles by 2.5 to 7.5 kGy of irradiation, compared to the control. Electron donating ability and shear force of ready-to-cook bulgogi was not significantly affected by gamma irradiation. Irradiation increased the 2-thiobarbituric acid reactive substances (TBARS) value. The irradiated, raw, ready-to-cook bulgogi had significantly higher scores in color and appearance than those of non-irradiated controls from sensory evaluation. The overall acceptance of cooked bulgogi had higher scores in non-irradiated or 2.5 kGy-irradiated bulgogi than the 5.0- or 7.5-kGy irradiated counterparts. In conclusion, irradiation at 2.5 kGy is recommended as a method to improve shelf-life, safety, and to achieve acceptable quality of ready-to-cook bulgogi without any adverse changes in the sensory characteristics.

• 한국항해항만학회지
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• 제42권2호
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• pp.97-106
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• 2018

Despite the development of safety measures and improvements in preventive systems technologies, maritime traffic accidents that involve ships carrying hazardous and noxious substances (HNS) continuously occur owing to increased amount of HNS goods transported and the growing number of HNS fleet. To prevent maritime traffic accidents involving ships carrying HNS, this study proposes an intuitive route risk assessment technique using risk contours that can be visually and quantitatively analyzed. The proposed technique offers continuous information based on quantified values. It determines and structures route risk factors classified as absolute danger, absolute factors, and influential factors within the assessment area. The route risk is assessed in accordance with the proposed algorithmic procedures by means of contour maps overlaid on electronic charts for visualization. To verify the effectiveness of the proposed route risk assessment technique, experimental case studies under various conditions were conducted to compare results obtained by the proposed technique to actual route plans used by five representative companies operating the model ship carrying HNS. This technique is beneficial not only for assessing the route risk of ships carrying HNS, but also for identifying better route options such as recommended routes and enhancing navigation safety. Furthermore, this technique can be used to develop optimized route plans for current maritime conditions in addition to future autonomous navigation application.

• Journal of applied mathematics & informatics
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• 제40권5_6호
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• pp.1151-1165
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• 2022

Key drive of information quarrying is to digest liked information starting possible information. With the colossal amount of realities kept in documents, information bases, and stores, in the medical care area, it's inexorably significant, assuming excessive, arising compelling resources aimed at examination besides comprehension like information on behalf of the withdrawal of gen that might assistance in independent direction. Classification is method in information mining; it's characterized as per private, passing on item toward a specific course established happening it is likeness toward past instances of different substances trendy the data collection. In pre-owned recycled four Classification algorithm that incorporate Multi-Layer perception, KSTAR, Bayesian Network and PART to fabricate the grouping replicas arranged the malaria data collection and analyze the replicas, degree their exhibition through Waikato Environment for Knowledge Analysis introduced to Java Development Kit 8, then utilizations outfit's technique trendy promoting presentation of the arrangement methodology. The outcome perceived that Bayesian Network return most elevated exactness of 50.05% when working on followed by Multi-Layer perception, with 49.9% when helping is half, then, at that point, Kstar with precision of 49.44%, 49.5% when supporting individually and PART have lesser precision of 48.1% when helping, The exploration recommended that Bayesian Network is awesome toward remain utilized on Malaria data collection in our sanatoriums.

• 한국산업보건학회지
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• 제33권4호
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• pp.455-463
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• 2023

Objectives: The aim of this study was to develop an air sampling and analytical method for estimating worker exposure to linear carbonate solvents and to evaluate the method. Methods: The target substances were three linear carbonates: DMC, DEC, EMC. GC/FID was used for sample analysis. Laboratory experiments were conducted to determine desorption solvents and sample capacity, and to evaluate storage stability, accuracy, and precision. Results: Coconut Shell Charcoal (CSC, 100/50 mg) was used as the air sampling media, and a desorption solvent of 5% methanol/95% dichloromethane was selected. Recommended sampling capacities were 1~11 ℓ for DMC, 1~18 ℓ for DEC, and 1~24 ℓ for EMC. The stability of three linear carbonates was demonstrated over 30 days in a refrigerator (4℃). Detection limits were determined as follows: DMC 0.26 ㎍/sample, DEC 0.24 ㎍/sample, and EMC 0.25 ㎍/sample. The total coefficient of variation was calculated as DMC 0.064, DEC 0.079, and EMC 0.07. Conclusions: This sampling and analysis method is suitable for estimating personal exposure to linear carbonates in the workplace.

• 분석과학
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• 제36권6호
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• pp.281-290
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• 2023

Zidovudine is an antiretroviral agent prescribed for the prevention and treatment of human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS). It is typically recommended to be used in combination with other antiretroviral drugs. Zidovudine has the potential to generate N-nitrosodimethylamine (NDMA) in the presence of dimethylamine and nitrite salt under acidic reaction conditions during the drug manufacturing process. NDMA is a potent human carcinogen that may be detected in drug substances or drug products. An analytical method was developed to determine NDMA in pharmaceuticals including zidovudine using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The analysis involved reversed-phase chromatography on a Kinetex F5 column with a mobile phase comprising water-acetonitrile mixtures. The detection of positively charged ions was conducted using atmospheric pressure chemical ionization (APCI). The calibration curve demonstrated excellent linearity (r = 0.9997) across the range of 1-50 ng/mL with a highly sensitive limit of detection (LOD) at 0.3 ng/mL. The developed method underwent thorough validation for specificity, linearity, accuracy, precision, robustness, and system suitability. This sensitive and specific analytical method was applied for detecting NDMA in zidovudine drug substance and its formulation currently available in the market, indicating its suitability for drug quality management purposes.

• 한국작물학회지
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• 제40권5호
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• pp.619-628
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• 1995

본 실험은 온실과 포장에서 재배한 알팔파를 잎, 줄기, 뿌리, 꽃 부분으로 나누어 수확, 건조,하여 물 추출한 후 이 추출물들이 알팔파 발아와 생육에 미치는 영향을 조사 비교하였으며 포장상태에서 자란 알팔파 지상부 전체를 수확,건조, 추출하여 이를 농도별로 처리 알팔파 발아율을 검정하였고, pot실험을 통하여 알팔파 품종간 biomass 분배율 검정과, 알팔파 autotoxicity를 해결하기 위한 방법으로 추출물을 adsorbent로 처리하여 이들이 알팔파 독성성분을 변형시키는지를 검토하였다. 1. 온실과 포장에서 자란 알팔파의 추출물로 알팔파 발아 및 생육에 대한 영향을 비교한 결과 포장에서 자란 추출물질이 발아와 생육에 더 억제적으로 작용하였고, 특히 포장에서 생육한 꽃 추출물 처리가 가장 억제적으로 작용하였다. 2. 농도처리에 따르는 추출물 처리는 농도가 증가 할수록 발아율이 억제되었고, biomass분배율에 대한 pot실험에서는 LWR 과 SLA의 산물인 LAR은 품종간 유의성을 보였다. 3. 알팔파 추출물에 대한 absorbents처리는 추출물의 독성을 변형시키지 못하였다.

• 대한화장품학회지
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• 제49권3호
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• pp.213-223
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• 2023

2022 년 1 월에서 11 월까지 유통 중인 수제비누 총 81 건을 수집하였다. 품질특성을 비교하기 위해 전성분 기재사항을 참조하였으며 pH, 건조감량, 중금속(납, 비소, 카드뮴, 안티몬 및 수은) 및 유리알칼리의 함량을 측정 하였다. 그 결과 pH 7.9 ~ 11.2, 평균 건조감량 17.6% 이었으며 유리알칼리는 거의 검출되지 않았다. 전체 시료의 중금속 평균값은 납 0.104 ㎍/g, 비소 0.035 ㎍/g, 카드뮴 0.002 ㎍/g, 안티몬 0.048 ㎍/g, 수은 0.0003 ㎍/g로 「화장품 안전기준 등에 관한 규정」에서 제시한 허용기준 납 20 ㎍/g, 비소 10 ㎍/g, 카드뮴 5 ㎍/g, 안티몬 10 ㎍/g 및 수은 1 ㎍/g 보다 매우 낮은 수준으로 검출되었다.

• 한국환경농학회지
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• 제32권4호
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• pp.260-267
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• 2013

본 연구는 고추재배시험 기간 동안 축분퇴비의 시용량과 비닐멀칭 유무에 따른 토양 유기탄소의 함량 변화와 토양 탄소의 안정화 정도를 조사하기 위해 실시되어졌다. 고추재배기간 동안 퇴비의 시용과 비닐멀칭 처리에 따라 토양 내 유기탄소 함량의 유의한 증가는 발견되어지지 않았다. 또한 퇴비시용과 비닐멀칭 처리에 의한 토양의 물리적 특성 변화는 관찰되지 않았다. 이러한 결과는 본 연구의 짧은 조사기간과 관련이 있는 것으로 판단된다. 그러나 퇴비의 시용에 의해 쉽게 분해 가능한 형태인 열수추출 가능한 탄소의 함량은 유의하게 감소하는 결과를 나타내었다. 추천량인 20 Mg/ha의 퇴비를 시용하였을 때 지하부의 바이오매스 함량이 최대를 나타내었다. 이상의 결과를 미루어 볼 때 장기적으로 추천량의 퇴비를 지속적으로 시용한다면 토양 유기탄소의 함량 증대와 안정화 정도를 향상시킬 수 있을 것으로 판단된다.

• International Journal of Industrial Entomology and Biomaterials
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• 제13권1호
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• pp.15-22
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• 2006

An experiment was conducted to study the efficiency of cyanobacterial biofertilizer (CBB) with chemical (NPK) fertilizer on quantitative and qualitative characters of mulberry variety Kanva-2. Their influences on silkworm growth and cocoon characters were also studied. Ten different CBB and NPK fertilizer treatments were given to 5000 plants of established mulberry garden. Treatments were of four types viz., (i) T1 to T7: single and combination dose of CBB+50% NPK (ii) T8: combination dose of CBB + 25%NPK, (iii) T9: CBB only and (iv) T10: control-l00% NPK. Soil pH decreased and nutrients status increased in CBB (T1- T9) treated plots. Average of ten crops data on quantitative traits revealed that T7 (CBB [N. muscorum (1.0 g), A. variahilis (1.0) and S. millei (1.0 g)] + 50% NPK) was very effective in improving growth parameters. Leaf yield was also found high in treatment T7 (32.12 tons/ha/yr.) followed by T10 (31.17 tons/ha/yr.) and T8 (27.67 tons/ha/yr.). Leaf quality characters were found high in T7 and low in T9. Most of the quality traits in T7 are on par with control no. The results revealed that reduction in the dose of chemical fertilizers in T7 did not affect the leaf yield and leaf quality traits of mulberry. This clearly indicates that the efficiency of CBB (T7) provides nitrogen, increases essential nutrients available in soil, maintain soil pH and supply growth substances required for the improvement of leaf yield and leaf quality of mulberry. Bioassay study also revealed no significant difference in silkworm growth and cocoon characters between treatments T7 and T10. Economics calculated revealed that T7 is highly economical and beneficial over T10 by gaining an amount of Rs. 660/-/acre/crop. Thus, treatment T7 containing N. muscorum (1.0 g), A. variahilis (1.0 g) and S. millei (1.0 g) + 50% NPK fertilizers can be recommended to sericulturists mainly to reduce the use of NPK fertilizers, by saving 50% of its cost and to improve soil fertility conditions, which in turn improves leaf yield and quality of mulberry.

• 한국환경성돌연변이발암원학회지
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• 제16권2호
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• pp.109-116
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• 1996

To study the effect of dietary $\omega 6/\omega 3$ fatty acid ratios on the preneoplastic lesions and lipid peroxidation in rat hepatocellular chemical carcinogenesis, placental glutathione S-transferase(GST-P) positive foci area and numbers, glucose 6-phosphatase(G6Pase) activity, thiobarbituric acid reactive substances (TBARS) were measured. Male Sprague-Dawley rats were fed 5 different diets-low $\omega 6/\omega 3$ ratio with fish oil (Low-F), low $\omega 6/\omega 3$ ratio with perilia oil(Low-P), moderate ratio with perilia oil(Moderate), blend of 10 different commercial fats and oils(High-BL) and high $\omega 6/\omega 3$ ratio(High)-for 8 weeks. Hepatocarcinogenesis was induced by modified Ito model. The area of GST-P positive loci was the lowest in Moderate group and in ascending order of Low-F < Low-P < High-BL < High. But statistically, only Moderate and High groups were significantly different. The number of GST-P positive foci showed the same trend as foci area. The activities of G6Pase, membrane stability marker, were increased as $\omega 6/\omega 3$ ratio decreased. Lipid peroxidation values (TBARS) were the lowest in Low-F group and it is significantly different from Moderate, High-BL and High groups. When dietary $\omega 6/\omega 3$ ratio was moderate(4.06), hepatocarcinogenesis was suppressed compared with high or low $\omega 6/\omega 3$ ratios. Blend fat, commonly consumed among Koreans, did not show any suppressive effect on carcinogenesis because of high ratio(6.7). These results suggest that dietary $\omega 6/\omega 3$ ratio influences hepatocellular chemical carcinogenesis. It is recommended that appropriate $\omega 6/\omega 3$ ratio should be around 4.0. and we recommend to use more $\omega 3$ fatty acid in food preparation to reduce the risk of hepatocarcinogenesis.