• 제목/요약/키워드: Real World

검색결과 4,242건 처리시간 0.03초

Real-World Compliance of Surgical Treatment According to the Korean Gastric Cancer Guideline 2018: Evaluation From the Nationwide Survey Data 2019 in Korea

  • Sang Soo Eom;Sin Hye Park;Bang Wool Eom;Hong Man Yoon;Young-Woo Kim;Keun Won Ryu
    • Journal of Gastric Cancer
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    • 제23권4호
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    • pp.535-548
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    • 2023
  • Purpose: This study evaluated real-world compliance with surgical treatment according to Korea's gastric cancer treatment guidelines. Materials and Methods: The 2018 Korean Gastric Cancer Treatment Guidelines were evaluated using the 2019 national survey data for surgically treated gastric cancer based on postoperative pathological results in Korea. In addition, the changes in surgical treatments in 2019 were compared with those in the 2014 national survey data implemented before the publication of the guidelines in 2018. The compliance rate was evaluated according to the algorithm recommended in the 2018 Korean guidelines. Results: The overall compliance rates in 2019 were 83% for gastric resection extent, 87% for lymph node dissection, 100% for surgical approach, and 83% for adjuvant chemotherapy, similar to 2014. Among patients with pathologic stages IB, II, and III disease who underwent total gastrectomy, the incidence of splenectomy was 8.08%, a practice not recommended by the guidelines. The survey findings revealed that 48.66% of the patients who underwent gastrectomy had pathological stage IV disease, which was not recommended by the 2019 guidelines. Compared to that in 2014, the rate of gastrectomy in stage IV patients was 54.53% in 2014. Compliance rates were similar across all regions of Korea, except for gastrectomy in patients with stage IV disease. Conclusions: Real-world compliance with gastric cancer treatment guidelines was relatively high in Korea.

Key Principles of Clinical Validation, Device Approval, and Insurance Coverage Decisions of Artificial Intelligence

  • Seong Ho Park;Jaesoon Choi;Jeong-Sik Byeon
    • Korean Journal of Radiology
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    • 제22권3호
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    • pp.442-453
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    • 2021
  • Artificial intelligence (AI) will likely affect various fields of medicine. This article aims to explain the fundamental principles of clinical validation, device approval, and insurance coverage decisions of AI algorithms for medical diagnosis and prediction. Discrimination accuracy of AI algorithms is often evaluated with the Dice similarity coefficient, sensitivity, specificity, and traditional or free-response receiver operating characteristic curves. Calibration accuracy should also be assessed, especially for algorithms that provide probabilities to users. As current AI algorithms have limited generalizability to real-world practice, clinical validation of AI should put it to proper external testing and assisting roles. External testing could adopt diagnostic case-control or diagnostic cohort designs. A diagnostic case-control study evaluates the technical validity/accuracy of AI while the latter tests the clinical validity/accuracy of AI in samples representing target patients in real-world clinical scenarios. Ultimate clinical validation of AI requires evaluations of its impact on patient outcomes, referred to as clinical utility, and for which randomized clinical trials are ideal. Device approval of AI is typically granted with proof of technical validity/accuracy and thus does not intend to directly indicate if AI is beneficial for patient care or if it improves patient outcomes. Neither can it categorically address the issue of limited generalizability of AI. After achieving device approval, it is up to medical professionals to determine if the approved AI algorithms are beneficial for real-world patient care. Insurance coverage decisions generally require a demonstration of clinical utility that the use of AI has improved patient outcomes.

Real-World Impact of Modern Reperfusion Therapy for Acute Ischemic Stroke : A Nationwide Population-Based Data Study in Korea

  • Yung Ki Park;Byul-Hee Yoon;Yu Deok Won;Jae Hoon Kim;Hee In Kang
    • Journal of Korean Neurosurgical Society
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    • 제67권2호
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    • pp.186-193
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    • 2024
  • Objective : The treatment paradigm for acute ischemic stroke has undergone several major changes in the past decade, contributing to improved patient prognosis in clinical practice. However, the extent to which these changes have affected patient prognosis in the real-world is yet to be clarified. This study aimed to evaluate the real-world impact of modern reperfusion therapy for acute ischemic stroke using data from the National Health Insurance Service in Korea. Methods : This study included patients aged 18-80 years who were admitted via the emergency room with an I63 code between 2011 and 2020. The rates of intravenous thrombolysis use and endovascular treatment according to the year of admission were investigated. Furthermore, the rates of decompressive craniectomy and 3-month mortality were also analyzed. The 10-year observational period was divided into three periods based on the 2015 guideline change as follows : prior, 2011-2014; transitional, 2015-2016; and modern, 2017-2020. Results : A total of 307117 patients (mean age, 65.7±10.9 years) were included, and most patients were male (59.7%). The rate of endovascular treatment gradually increased during the study period from 0.71% in the prior period to 1.32% in the transitional period and finally to 1.85% in the modern period. Meanwhile, the 3-month mortality rate gradually decreased from 4.78% in the prior period to 4.03% in the transitional period and to 3.71% in the modern period. Conclusion : In Korea, the mortality rate decreased as the rate of modern reperfusion therapy increased in patients with acute ischemic stroke. Overall, technical and scientific advances in reperfusion therapy have improved the outcome of patients with acute ischemic stroke in Korea.

AR 기반 정보 시스템에 대한 아동 인식 연구 (Augmented Reality Based Information Systems: An Exploratory Study of Understanding Children's Perception)

  • 최시영;이경진
    • 정보관리학회지
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    • 제41권1호
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    • pp.85-105
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    • 2024
  • 도서관은 어린이들이 신기술을 활용할 수 있는 기회를 적극적으로 제공하는 공공기관으로, 미래 세대를 위한 다양한 기술 기반 정보 시스템의 영향력에 대한 이해가 필요하다. 증강 현실(Augmented Reality)은 최근 어린이들의 교육, 치료, 여가 등 다양한 분야에 활발히 적용되고 있는 기술이다. 그러나 이러한 발전에도 불구하고 어린이들의 AR에 대한 인식과 요구에 대한 연구는 제한적인 실정이다. 따라서 본 연구에서는 공동 디자인 세션을 통해 AR 기술에 대한 어린이들의 인식과 요구를 직접적으로 조사하고자 하였다. 'Would You Rather?' 기법을 통해 어린아이들은 AR 기술에 대한 경계와 기대를 동시에 가지고 있으며, AR 기술 환경을 현실 세계의 확장으로 간주한다는 것을 확인할 수 있었다. 본 연구는 향후 도서관에서 어린이를 위한 AR 콘텐츠를 개발할 때에 고려해야 하는 요소를 제안한다는 점에서 의의를 지닌다.

Coronary Intravascular Lithotripsy Versus Rotational Atherectomy in an Asian Population: Clinical Outcomes in Real-World Patients

  • Jie Jun Wong;Sridharan Umapathy;Yann Shan Keh;Yee How Lau;Jonathan Yap;Muhammad Idu;Chee Yang Chin;Jiang Ming Fam;Boon Wah Liew;Chee Tang Chin;Philip En Hou Wong;Tian Hai Koh;Khung Keong Yeo
    • Korean Circulation Journal
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    • 제52권4호
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    • pp.288-300
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    • 2022
  • Background and Objectives: We compared real-world clinical outcomes of patients receiving intravascular lithotripsy (IVL) versus rotational atherectomy (RA) for heavily calcified coronary lesions. Methods: Fifty-three patients who received IVL from January 2017 to July 2020 were retrospectively compared to 271 patients who received RA from January 2017 to December 2018. Primary endpoints were in-hospital and 30-day major adverse cardiovascular events (MACE). Results: IVL patients had a higher prevalence of acute coronary syndrome (56.6% vs 24.4, p<0.001), multivessel disease (96.2% vs 73.3%, p<0.001) and emergency procedures (17.0% vs 2.2%, p<0.001) compared to RA. In-hospital MACE (11.3% vs 5.9%, p=0.152), MI (7.5% vs 3.3%, p=0.152), and mortality (5.7% vs 3.0%, p=0.319) were not statistically significant. 30-day MACE was higher in the IVL cohort vs RA (17.0% vs 7.4%, p=0.035). Propensity score adjusted regression using IVL was also performed on in-hospital MACE (odds ratio [OR], 1.677; 95% confidence interval [CI], 0.588-4.779) and 30-day MACE (OR, 1.910; 95% CI, 0.774-4.718). Conclusions: These findings represent our initial IVL experience in a high-risk, real-world cohort. Although the event rate in the IVL arm was numerically higher compared to RA, the small numbers and retrospective nature of this study preclude definitive conclusions. These clinical outcomes are likely to improve with greater experience and better case selection, allowing IVL to effectively treat complex calcified coronary lesions.

블록체인 거래소 플랫폼을 활용한 RWA 토큰 거래에서의 개인정보보호 개선 방안 (nhancing Anonymity Protection in RWA Token Trading Using Blockchain Exchange Platforms)

  • 이재성;이중희
    • 정보보호학회논문지
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    • 제34권4호
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    • pp.641-649
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    • 2024
  • 본 논문은 최근 몇 년간 암호화폐 시장에서 가장 두드러진 이슈 중 하나인 실제 자산 토큰, 즉 RWA(Real-World Assets) 토큰의 토큰 거래와 관련된 익명성 보호 문제를 다룬다. 블록체인 기술의 투명성 원칙상 거래자의 익명성을 보장하기 어렵지만, 기존 블록체인 연구에서 대체 가능 토큰(FT)의 프라이버시 보호를 위해 믹서 서비스를 이용하는 경우가 있었으며 대체 불가능 토큰(NFT)의 프라이버시 보호를 위한 선행 연구가 있었다. 그러나 FT와 NFT의 특성을 모두 지닐 수 있으며 실물 자산과 연계된 RWA 토큰은 그 구조상 어느 한 방법만을 사용해서는 익명성 보호라는 목표를 효과적으로 달성하기 어렵다. 본 논문에서는 가상의 토큰 거래 플랫폼인 ARTeX를 제안하고 거래 프로세스를 설명함으로써 RWA 토큰의 익명성 보호를 위한 방안을 분석한다.

웹을 기반으로 하는 자동화 방법에 관한 연구

  • 박종락;정원;박관희
    • 한국정보시스템학회:학술대회논문집
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    • 한국정보시스템학회 2003년도 춘계학술대회
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    • pp.45-54
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    • 2003
  • Over the past decade, the unprecedented internet revolution has dramatically altered many core aspects of out daily business and personal lives. Many of these fundamental changes have completely transformed traditional communication mechanism, boosted productivity, opened up new marketing opportunities, and given birth to entirely new applications in the world of eCommerce and eBusiness. But Many web applications doesn't connect with real-world device such as lights, pumps, and Motors avaiable over the Internet. In this paper We introduce XML and presents way it can be used with I/O system.

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사이버 공간 상에서의 감성 오디오 디자인 (Emotional Audio Design in Cyber Space)

  • 박정순
    • 한국감성과학회:학술대회논문집
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    • 한국감성과학회 2000년도 춘계 학술대회 및 국제 감성공학 심포지움 논문집 Proceeding of the 2000 Spring Conference of KOSES and International Sensibility Ergonomics Symposium
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    • pp.244-247
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    • 2000
  • 웹은 정보화시태의 새로운 커뮤니케이션 매체로서 실제세계(real world)를 그대로 옮겨 놓은 가상세계(virtual world, cyber space)라 할 수 있으며 또 다른 한의 생활공간이기도 하다. 이런 가상공간 안에서 사용되는 가상제품(cyber product)들은 실제세계에서의 물리적인 제품과는 달리 형태의 파괴, 무제한적인 색상과 재질감, 유니크한 작동메카니즘과 인터렉티브한 요소에 의해 기계가 아닌 하나의 생명체로서 감성을 지닌 제품 디자인이 가능하다. 이에 본 연구에서는 이런 특성에 따라 실제세계의 오디오에서 느낄 수 없는 새로운 즐거움을 주는 사이버공간상에서의 시청각오디오를 디자인하였다.

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Measurement Based on Socio-Cultural Background

  • Choi-Koh, Sang-Sook
    • 한국수학교육학회지시리즈D:수학교육연구
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    • 제5권2호
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    • pp.99-106
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    • 2001
  • We have known that ethno-mathematics is a field of a study that emphasizes the socio-cultural environment in which a person "does" mathematics as stated by D'Ambrosio(Ethno mathematics and its Place in the History and Pedagogy of Mathematics, 1985). Measurement is an important mathematical topic, which leads students to relate math to the eal-world applications, particularly with socio-cultural aspects. The purpose of this article is to review the history of the measurement system in Korea briefly and to adapt the measurement system into real-world problems so that children acquire measurement knowledge in the most natural way.

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3D 모바일 게임 내의 가상카메라를 위한 자이로 센서의 민감도 설정 방법 (Method of Sensitivity Configuration of Gyro Sensor for Virtual Camera inside 3D Mobile Game)

  • 백인식;김종국
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2014년도 춘계학술발표대회
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    • pp.1020-1022
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    • 2014
  • In this paper, we present a method for smartphone users to have a better user experience when playing 3D mobile games using the gyro sensor. We designed the rotation of the virtual camera in the game world to be proportional to the real-world's rotation. We have also made the sensitivity configuration possible for users to manipulate.