• The Journal of the Convergence on Culture Technology
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• v.4 no.4
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• pp.429-438
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• 2018

Recently, there has been a tendency for accidents occurring in manufacturing to lead to serious accidents and serious industrial accidents and to extend to community disasters. In accordance with the Third Plan (2015-2019) of the National Security Management Plan, the Safety Administration announces and promotes improvement measures to minimize industrial accidents and disasters. In the case of industrial accidents from KOSHA 2015 to 2017, the accident rate of the metal-related manufacturing industry is 1.57%, which is more than three times higher than the average 0.50% of all industries. As a result of investigating the causes of disasters, 72% of workers were found to be caused by unsafe behaviors. In addition, insecure behaviors are closely related to safety consciousness, and a survey on safety consciousness was conducted for workers in this field. Safety consciousness improvement has the affirmative effect on accident prevention and it is a factor to reduce accidents.

• Fisheries and Aquatic Sciences
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• v.25 no.2
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• pp.90-100
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• 2022

Cardiovascular diseases (CVDs) have posed serious public health problems, accounting for nearly 30% of mortality worldwide and their incidence is still increasing. Therefore, new treatment resources are necessary to prevent or manage the ever-increasing population of patients with CVDs. Sea cucumber is well known for its medical and health benefit effects, but it is not well known what/how effect it has on vascular disease. In the present study, we examined the protect effect of sea cucumber, Apostichopus japonicus 80% ethanol extract (AJE) on zebrafish embryo with the stimulation of free fatty acid, palmitate (PA). In vivo study showed that AJE can attenuate PA-induced toxicity through relieving the rapid heartbeat, increasing the survival rate and reducing the malformation in both wild type and Tg (fli1a:eGFP) transgenic zebrafish lines. Additionally, compare with PA treated embryos, the yolk sac area, body length, axial vascular segment (AVS) and intersegmental vessel (ISV) of the co-treatment group of AJE and PA were comparable to the control group. Moreover, AJE lowered the expression of inducible nitric oxide synthase (iNOS), nitric oxide (NO) and inflammation-related genes induced by PA, and inhibited PA-induced vascular development disorders. Our data preliminarily verify that AJE could be a candidate resource for the prevention or therapy of CVDs.

• The Korean Journal of Physiology and Pharmacology
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• v.5 no.4
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• pp.333-342
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• 2001

Adriamycin is a commonly used chemotherapeutic agent for cancer, including acute leukemia, lymphoma, and a number of solid human tumors. However, recent studies have recognized severe cardiotoxicity after an acute dose, which are likely the result of generation of free radicals and lipid peroxidation. Therefore, the clinical uses of adriamycin have been limited. Melatonin, the pineal gland hormone known for its ability to modulate circardian rhythm, has recently been studied in its several functions, including cancer growth inhibition, stimulating the immune system, and acting as an antioxidant and radical scavenging effects. In the present study, we evaluated the effect of melatonin administration on adriamycin-induced cardiotoxicity in rat. Heart slices were prepared using a Stadie-Riggs microtome for the measurement of malondialdehyde (MDA) content used as an index of lipid peroxidation and lactate dehydrogenase (LDH) release as an indicator of lethal cell injury. Serious adriamycin-induced lethality was observed in rat by a single intraperitoneal injection in a dose-dependent manner. A single injection of adriamycin (25 mg/kg, i.p.) induced a lethality rate of 86%, with melatonin (10 mg/kg s.c. for 6 days) treatment reducing the adriamycin-induced lethality rate to 20%. The severe body weight loss caused by adriamycin was also significantly attenuated by melatonin treatment. Treatment of melatonin marked reduced adriamycin-induced the levels of MDA formation and LDH release. A cell damage indicated by the loss of myofibrils, swelling of the mitochondria as well as cytoplasmic vacuolization was seen in adriamycin-treated group. Melatonin attenuated the adriamycin-induced structural alterations. These data provide evidence that melatonin prevents adriamycin-induced cardiotoxicity and might serve as a combination with adriamycin to limit free radical-mediated cardiotoxicity.

• Tuberculosis and Respiratory Diseases
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• v.61 no.5
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• pp.473-478
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• 2006

Transfusion related acute lung injury (TRALI) is a serious, potentially life-threatening complication of transfusion therapy that is sometimes under diagnosed and under reported. Patients with TRALI present with dyspnea/respiratory distress and fever. The symptoms, signs and chest radiological findings in TRALI are similar to transfusion associated circulatory overload, which makes it is difficult to distinguish it from circulatory overload. Although the mortality rate in cases of TRALI is relatively low, TRALI is the third most common cause of fatal transfusion reactions next to ABO blood type incompatibility and hepatitis. Mild-to-moderate cases of TRALI may be misdiagnosed as volume overload. Recently, we encountered two cases where the patients suffered from dyspnea and fever after a transfusion. and review of the relevant literature.

• Journal of the Korean Society of Safety
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• v.32 no.3
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• pp.48-53
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• 2017

Many construction accidents can be lead to a death occurring at construction sites. These are considerably due to potentially-hazardous equipment and machine or unexpected collapsion at earth work due to land slide and so on. Almost 50% of the total death and injury, occurred in construction sites in 2015. 66% of those serious accidents are due to falling occurring from construction sites when they work. Therefore, causes and recommendations of each accident should be deeply thought and analysed The indirect causes are directly related to safe consciousness of the construction workers. Actually, their safety consciousness are not high, even very low, it is thought. Questionnaire survey sheets have been distributed to Seoul, Incheon, and Gyunggi-Do area, first. And then, the authors have collected those directly at sites, in order to increase collection rate of the sheets. The totally, collected sheets are 295 sheets. And, they are analysed using SPSS version 19 package program. Workers internal consciousness has been investigated and reviewed and analysed by statistical method such as frequency rate, crossed, and correlated analysis. And finally the conclusions for the above analyses are as follows; Heavy weight worth a crew of more than two workers should be necessarily considered for the advanced safety plan and needed for making a highly potential hazard group at construction sites. Safety consciousness, earing p.p.e, workman ship should be mainly considered for investing safety costs with an aspect of human factor.

• Journal of Korean Neurosurgical Society
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• v.66 no.3
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• pp.228-238
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• 2023

Intraventricular hemorrhage (IVH) is a serious concern for preterm infants and can predispose such infants to brain injury and poor neurodevelopmental outcomes. IVH is particularly common in preterm infants. Although advances in obstetric management and neonatal care have led to a lower mortality rate for preterm infants with IVH, the IVH-related morbidity rate in this population remains high. Therefore, the present review investigated the pathophysiology of IVH and the evidence related to interventions for prevention. The analysis of the pathophysiology of IVH was conducted with a focus on the factors associated with cerebral hemodynamics, vulnerabilities in the structure of cerebral vessels, and host or genetic predisposing factors. The findings presented in the literature indicate that fluctuations in cerebral blood flow, the presence of hemodynamic significant patent ductus arteriosus, arterial carbon dioxide tension, and impaired cerebral venous drainage; a vulnerable or fragile capillary network; and a genetic variant associated with a mechanism underlying IVH development may lead to preterm infants developing IVH. Therefore, strategies focused on antenatal management, such as routine corticosteroid administration and magnesium sulfate use; perinatal management, such as maternal transfer to a specialized center; and postnatal management, including pharmacological agent administration and circulatory management involving prevention of extreme blood pressure, hemodynamic significant patent ductus arteriosus management, and optimization of cardiac function, can lower the likelihood of IVH development in preterm infants. Incorporating neuroprotective care bundles into routine care for such infants may also reduce the likelihood of IVH development. The findings regarding the pathogenesis of IVH further indicate that cerebrovascular status and systemic hemodynamic changes must be analyzed and monitored in preterm infants and that individualized management strategies must be developed with consideration of the risk factors for and physiological status of each preterm infant.

• The Journal of Korean Orthopaedic Ultrasound Society
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• v.7 no.1
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• pp.67-75
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• 2014

There are several kinds of regional nerve blockades, such as interscalene brachial plexus block, C5 root block, suprascapular nerve block, and axillary nerve block, which can be applied for anesthesia and postoperative pain control after shoulder surgeries. These regional nerve blockades have shown good results, but high failure rate and serious complications, such as phrenic nerve palsy, pneumothorax, and nerve injury, still remain. Ultrasound-guided intervention can increase the success rate of nerve blockades and reduce complications. We described the method of ultrasound-guided intervention for the regional nerve blockades around shoulder.

• Asian Journal of Turfgrass Science
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• v.19 no.2
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• pp.131-140
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• 2005

This study was conducted to compare cold tolerances and growth rates of 5 basic species, commercial lines, and breeding lines of zoysiagrass. Total 41 zoysiagrasses were tested at the northern part (Jeokseong-myeon) and the middle part (Cheonan) of South Korea. Cold tolerance (survival rate during winter), growth rate, green-up speed, and density data were collected visually. Four types of zoysiagrasses (Z. matrella, Z. tenuifolia, USm, and S4M2) with genetic characteristics of Z. matrella died during winter cold, while the others survived. Midium leaf type zoysiagrasses, such as Anyang1, Samdeock1, Anyang2, SJ21, and Pyeongdong, with genetic characteristics of both Z. sinica and Z. macrostachya showed vigorous growth rate one year after planting at the northern part (Jeokseong-myeon). Twenty nine ($70.7\%$) zoysiagrasses showed vigorous growth rate, but the other twelve ($29.3\%$) zoysiagrasses died by cold and drought condition at the middle (Cheonan) part of S. Korea. Anyang2, AJ9-7, Samdeock1, Samdeock2, Samdeock3, and Zenith-C showed vigorous growth rate even though cold and drought environmental condition were artificially provided at these region. But, SJ2-19, NSm, 88Mey, 88Mey-7S, 88Mey-9S, SJ2l-10, ASm, and DBm which did not die at the northern part, showed serious injury at the middle part of S. korea. From this results, we can conclude that drought is as important factor as low temperature for zoysiagrasses during winter.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.51 no.2
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• pp.188-194
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• 2015

The powered purse seine fishery is an important fishery accounting for 19.4% of adjacent water fishery production in Korea, and the commercial fishing is associated with high rate of fatal and non-fatal occupational injury. The hazard analysis for the fishermen's safety of offshore large powered purse seiner was conducted to serve as a basic data for improving the healthy and safe working environment of fishermen using fishermen's occupational accidents of the national federation of fisheries cooperatives (NFFC) in 2013 (n=583). As a result, the occupational accident occurrence rate of this fishery was 182.6‰ in all industries 30.9 times the rate of that. In addition, death and missing rate was found to have a very serious level management to 25.1‰ in all industries of death of 17.5 times. The accident occurred in 72.3 to 85.8% was happened at sea. The others, slipping and struck by object etc occurred more frequently in order in the frequency of accident occurrence pattern. However, the occurrence rate of death and missing did not match the frequency of accident pattern. In other words, slipping occurred frequently higher while death and missing risk was not high. And the contact with fishing gear and fall in the waters was low while death and missing risk was high. The results are expected to contribute for identification and assessment of safety hazard occurred in offshore large powered purse seiners.

• Journal of Fisheries and Marine Sciences Education
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• v.27 no.4
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• pp.1129-1135
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• 2015

The stow net is a stationary gear made from netting, usually in shape like trawl net without wings. The nets are fixed by means of anchors, placed according to the direction and strength of the current. And the commercial fishing is associated with high rate of fatal and non-fatal occupational injury. The hazard factors analysis for the fishermen's safety of offshore stow nets vessel was conducted to serve as a basic data for improving the healthy and safe working environment of fishermen using fishermen's occupational accidents of the national federation of fisheries cooperatives (NFFC) from 2012 to 2014 (n=1,144). As a result, the average occupational accident occurrence rate of this fishery was 206.9‰ in all industries 36.9 times the rate of that. In addition, average death and missing rate was found to have a very serious level management to 50.4‰ in all industries of death of 42.0 times. The accident occurred in 84.5 to 94.6% was happened at sea. The struck by object, slipping, contact with machinery, contact by object or gear and others occurred more frequently in order on the frequency of accident occurrence pattern. However, the occurrence rate of death and missing did not match the frequency of accident pattern. In other words, slipping occurred frequently higher while death and missing risk was not high. And the contact with fishing gear and fall in the waters was low while death and missing risk was high. The results are expected to contribute for identification and assessment of safety hazard occurred in offshore stow nets vessel.