• Structural Engineering and Mechanics
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• 제27권1호
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• pp.77-97
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• 2007

When assessing buildings that may collapse during a large earthquake, conventional rapid visual screening procedures generally provide good results when identifying buildings for further investigation. Unfortunately, their accuracy at identify buildings at risk is not so good. In addition, there appears to be little room for improvement. This paper investigates an alternative screening procedure based on fuzzy logic and artificial neural networks. Two databases of buildings damaged during the Athens earthquake of 1999 are used for training purposes. Extremely good results are obtained from one database and not so good results are obtained from the second database. This finding illustrates the importance of specifically collecting data tailored to the requirements of the fuzzy logic based rapid visual screening procedure. In general, results demonstrate that the trained fuzzy logic based rapid visual screening procedure represents a marked improvement when identifying buildings at risk. In particular, when smaller percentages of the buildings with high damage scores are extracted for further investigation, the proposed fuzzy screening procedure becomes more efficient. This paper shows that the proposed procedure has a significant optimisation potential, is worth pursuing and, to this end, a strategy that outlines the future development of the fuzzy logic based rapid visual screening procedure is proposed.

• 대한치과의사협회지
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• 제49권1호
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• pp.38-44
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• 2011

The aim of this study is to evaluate the patient's and clinician's response to rapid oral HIV screening test. Attitude assessment survey was carried out on patients test with rapid oral HIV screening test and clinicians who conducted the test. The patients and clinicians were present at the dental hospital and clinics which were participating in the research project, between March and May 2010. Rapid oral HIV screening test is safe and efficient to the patients. It also demonstrated reliability to accuracy and confidentiality, and high recommendation to rapid oral HIV screening test. The clinician survey revealed high test convenience and high appraisal to patient satisfaction. In conclusion, if rapid oral HIV screening test becomes more common, patients will receive safe and convenient and high reliable HIV infection test, while clinicians will be able to create safe dental care environment.

• 한국공간구조학회지
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• 제11권1호
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• pp.11-14
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• 2011

• 대한치과의사협회지
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• 제47권5호
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• pp.291-296
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• 2009

Purpose : The aim of this studγ was to evaluate the patient's and dentist's perspective and knowledge on rapid human immunodeficiency virus screening test in dental setting. Material and Methods: In March 2009, 100 patients and 100 dentists at College of Dentistry, Yonsei University were provided an attitude assessment survey. Results : Results were analyzed for acceptance of testing and potential barriers. 94% of patients agreed to take a rapid HIV screening test and 77% of dentists were willing to provide the test to their patients. Also the current knowledge state of patients and dentists on HIV infection was not accurate as expected. Conclusion : Overall, dental clinic patients widely accepted the offer of rapid oral HIV screening. Rapid HIV screening test in the dental setting ran be an important option to increase the number of individuals who know their HIV status.

• 한국공간구조학회논문집
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• 제11권2호
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• pp.55-62
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• 2011

최근 테러의 발생빈도가 증가하는 가운데 테러는 불특정 다수의 사람이 모이는 건물에서 집중적으로 발생하고 있다. 이중 고층, 초고층 빌딩에서 발생하는 테러는 막대한 피해를 발생시킨다. 이에 따른 건물의 테러피해 경감을 위한 다양한 연구가 필요하다. 본 논문에서는 비교적 수행절차가 간단하며 단기간에 실행이 가능한 Fema 455 - Rapid Visual Screening을 통해 현재 사용 중인 국내 고층 초고층 건물의 테러에 대한 위험도를 평가하여 국내 건물이 가지는 공통적인 테러 위험요소를 확인하였다. 평가결과 대상 건물은 모두 중위험도의 범위에 있다. 이는 국내 고층, 초고층 건물의 외부 환경적인 특징이 비슷한 데에 그 원인이 있었다.

• 한국공간구조학회논문집
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• 제11권4호
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• pp.89-99
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• 2011

최근 테러의 대상 범위는 보다 광범위해 지고 있으며, 국내의 테러발생위험이 지속적으로 증가하고 있는 가운데 테러의 형태는 국가의 중요시설과 같은 경성표적(Hard Target)에서 초고층건물과 같은 다중이용시설의 연성표적(Soft Target)으로 변화하고 있다. 따라서 본 논문에서는 Fema 455 - Rapid Visual Screening을 통해 국내의 초고층건물과 고층건물의 테러위험도 평가결과를 국내의 저층건물의 테러위험도 평가결과와 비교하여 초고층건물의 테러위험도를 분석하였다. 그 결과 초고층건물 및 고층건물은 저층건물에 비해 Consequences, Vulnerability Rating보다 Threat Rating항목이 상대적으로 높았으며, 이는 초고층건물의 거주인원 및 국가적 또는 지역적인 상징성 및 가시성 부분에서 테러위험도가 높은 것이 주요 원인으로 분석되었다.

• Journal of Korean Medical Science
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• 제33권46호
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• pp.304.1-304.7
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• 2018

Background: The Republic of Korea has a very low prevalence of human immunodeficiency virus (HIV) infection, but the number of new HIV diagnoses has steadily risen, strongly indicating a large number of undetected HIV infections. Thus, it is important for Korean public health authorities to adopt and encourage cost-effective HIV detection tools, such as rapid HIV screening tests. In this study, we aimed to evaluate the cost-effectiveness of enzyme-linked immunosorbent assays (ELISA) and rapid tests in a public health center (PHC) setting. Methods: We developed a decision analytic model to assess the per-examinee cost and the cost-effectiveness of identifying HIV patients in a PHC setting using two HIV testing strategies: conventional HIV screening by ELISA versus rapid HIV testing. Analysis was performed in two scenarios: HIV testing in an average-risk population and in a high-risk population. Results: Compared to the ELISA, the rapid test was cost-saving and cost-effective. The per-examinee cost was USD 1.61 with rapid testing versus USD 3.38 with ELISA in an average-risk population, and USD 4.77 with rapid testing versus USD 7.62 with ELISA in a high-risk population. The cost of identifying a previously undiagnosed HIV case was USD 26,974 with rapid testing versus USD 42,237 with ELISA in an average-risk population, and USD 153 with rapid testing versus USD 183 with ELISA in a high-risk population. Conclusion: Rapid testing would be more cost-effective than using conventional ELISA testing for identifying previously undiagnosed HIV-infected cases in Korea, a country with extremely low HIV prevalence.

• KSBB Journal
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• 제23권6호
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• pp.484-488
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• 2008

본 연구에서는 peroxidase 활성의 신속한 스크리닝을 위해 peroxidase의 활성을 정량적으로 평가할 수 있는 분석으로 agar plate와 96-well plate에서 peroxdase의 활성에 비례하여 색상감도를 측정할 수 있는 colorimetric 분석법을 개발하였다. 이 방법은 RP-HPLC 결과와 매우 비례적으로 상관적인 결과를 보였다. 이 colorimetric 분석법을 사용하여, 폐수에서 한천 고체배지에서 7회에 걸친 스크리닝으로 높은 농도의 2,4-DCP(1000 ppm)에서 생존하는 균주를 스크리닝하였고 선별된 이들 균주들은 탄소원으로 2,4-DCP 만을 대사할 수 있으며 높은 peroxidase 생산량을 보였다. 분리된 균주들 중 높은 peroxidase 활성을 가지는 2,4-DCP 분해 균주를 분리하였고 최종 분리된 균주는 염색폐수의 COD를 4시간 동안 44%에서 61%까지 제거하였다. 상기의 결과에 의해 본 연구에서 개발된 발색법이 페놀화합물 분해 균주 스크리닝법이 빠르고 쉬운 난분해성 물질인 페놀 혼합물의 분해 균주 탐색에 대하여 성공적으로 적용될 수 있기를 기대한다.

• Journal of Microbiology and Biotechnology
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• 제33권5호
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• pp.698-705
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• 2023

Rapid diagnosis of methicillin-resistant Staphylococcus aureus (MRSA) is essential for guiding clinical treatment and preventing the spread of MRSA infections. Herein, we present a simple and rapid MRSA screening test based on the aggregation effect of mannose-binding lectin (MBL)-conjugated gold nanoparticles (AuNP), called the MRSA probe. Recombinant MBL protein is a member of the lectin family and part of the innate immune system. It can recognize wall teichoic acid (WTA) on the membrane of MRSA more specifically than that of methicillin-sensitive Staphylococcus aureus (MSSA) under optimized salt conditions. Thus, the MRSA probe can selectively bind to MRSA, and the aggregation of the probes on the surface of the target bacteria can be detected and analyzed by the naked eye within 5 min. To demonstrate the suitability of the method for real-world application, we tested 40 clinical S. aureus isolates (including 20 MRSA specimens) and recorded a sensitivity of 100%. In conclusion, the MRSA probe-based screening test with its excellent sensitivity has the potential for successful application in the microbiology laboratory.

• Archives of Pharmacal Research
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• 제17권3호
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• pp.175-181
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• 1994

The solid-phase extraction (SPF) with subsequent tert-butyldimethylsilyl (TBDMS) derivatization was investigated for the rapid profiling and screening of various carboxylated non-steroidal antiinflammatory drugs (NSAIDs) simultaneously in biological fluid samples. Compared to the conventional SPF in adsorption mode using Chromosorb 102, Chromosorb 107, Carbopak B and Thermosorb, the SPF in partition mode using Chromosorb P as the adsorbent, and ethyl acetate/methylene chloride as the eluting solvents provided hightest overall recovenies of the NSAIDs from aqueous solutions with good precision. The solid-phase extracted NASIDs were silylated with N-methyl-N-(tert-butyldimethylsily)trifuoroacetamide to TBDMS derivatives and directly analyzed by capillary gas chromatography and gs chromatography-mass spectrometry. The usefulness of the present method was examined for the profilling and screening of saliva, serum and urine samples for various NSAIDs simultaneously.