• Title/Summary/Keyword: Randomized controlled trials

검색결과 1,181건 처리시간 0.028초

편두통의 침 치료에 대한 임상 연구 동향 분석 - 2012년도 이후 Pubmed 검색 중심으로 (Research Trend of Acupuncture Therapy on Migraine - Focus on Pubmed Searches from 2012 to 2017)

  • 최기훈;김은지;권오훈;김광휘;김태연;이태걸
    • 대한한방내과학회지
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    • 제39권2호
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    • pp.237-246
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    • 2018
  • Objective: To compare recent domestic and overseas research trends about acupuncture therapies on migraines. Method: Case reports and randomized controlled trials were searched via Pubmed. Searches were limited to publications between 2012 and 2017. Results: Four case reports and twelve randomized controlled trials were searched from Pubmed. Research showed that acupuncture therapies are more significantly effective than other therapies, such as sham acupunctures and Western medicines. Conclusion: There has been more active overseas research about acupuncture therapies on migraine compared to domestic studies. To examine the efficacy and suitability of acupuncture therapies on Koreans with migraines, domestic studies and research should be conducted more actively.

고혈압 침치료에 관한 최근 연구 동향 고찰 - Pubmed와 국내 논문 중심으로 - (A Review of Recent Acupuncture Treatment for Hypertension - PubMed and Domestic Studies)

  • 김승연;원재호;이인
    • 대한한방내과학회지
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    • 제41권1호
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    • pp.29-43
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    • 2020
  • Objectives: The purpose of this study was to summarize current research trends and results regarding acupuncture treatment for hypertension. Methods: Articles published from 2009 to 2019 were searched on domestic databases (OASIS, NDSL, RISS) and PubMed using the keywords 'Hypertension', 'Hypertensive', 'Acupuncture', 'EA' (electroacupuncture), 'Autonomic nervous system', 'ANS', 'CVD' (cardiovascular disease), '고혈압', '침', '전침', and '자율신경계'. The studies were analyzed according to the year, type of study (domestic or foreign articles, nationality of the first author), acupuncture type for human and animal studies, BP (blood pressure) measurement, and acupuncture intervention. Results: In total, 21 articles were selected. There were 8 randomized controlled trials (RCTs), 3 non-randomized controlled trials (nRCTs), 2 before-after studies, 1 case series, and 7 animal studies. Manual acupuncture (11 articles) was most frequently used, and ST36 (足三里) was most frequently used in human studies. In 18 of 21 articles, acupuncture was reported as effective in lowering systolic blood pressure (SBP) or diastolic blood pressure (DBP) in hypertensive patients. Conclusions: Acupuncture treatment for hypertension is deemed useful. Further studies are necessary for application of acupuncture therapy in clinical practice.

미숙아의 장관영양 (Enteral Feeding for Preterm Infants-Benefits and Risks)

  • 신종범
    • Neonatal Medicine
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    • 제16권2호
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    • pp.121-130
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    • 2009
  • Over the past 20 years, neonatal mortality rates for preterm infants, particularly those born extremely preterm and with a very low birth weight, have decreased steadily. As more very immature preterm infants survive, provision of enteral feeding has become a major focus of concern. According to many experts on neonatal nutrition, the goal for the nutrition of preterm infants should be to achieve a postnatal growth rate approximating that of a normal fetus of the same gestational age. Total parenteral nutrition for maintaining nutritional integrity is mandatory before successful transition to enteral feeding. Early initiation of trophic enteral feeding is vital for postnatal adaptation. Recently published randomized controlled trials provide no evidence to support the practice of postponing enteral feeding to reduce the incidence of necrotizing enterocolitis. Early trophic feeding yields demonstrable benefits and there is currently no evidence of any adverse effects following early feeding. Preterm milk from the infant's own mother is the milk of choice, which can always be supplemented with a human milk fortifier. Here we review over 50 randomized controlled trials and over seven systematic reviews published on neonatal parenteral and enteral feeding of preterm infants. Neonatologists must make use of the evidence from these studies as a reference for feeding protocols for preterm infants in their NICUs are to be based.

골관절염에 대한 추나요법을 포함한 중의학치료의 효과 : 체계적 문헌 고찰 (Chinese Medicine including Chuna Manual Therapy for Osteoarthritis : A Systematic Review)

  • 김한결;권태우;김병준
    • 척추신경추나의학회지
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    • 제13권1호
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    • pp.11-21
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    • 2018
  • Objectives: To evaluate the evidence supporting the effectiveness and safety of Chinese medicine, including Chuna manual therapy, for the treatment ofosteoarthritis. Methods: We conducted a search of 8 electronic databases(Pubmed, Web of Science, EMBASE, Cochrane Library, CAJ, KISTI, NDSL, and RISS) to find all randomized controlled clinical trials that discuss Chuna manual therapy forosteoarthritis till May 2018. Results: Our inclusion criteria selected 7eligible RCTs involving 633 participants. The meta-analysis of 6 studies showed positive results for the useof Chinese medicine, including Chuna manual therapy, for treating knee osteoarthritis. There was no evidence of worsening symptoms or any adverse events. Conclusions: Our systematic review found favorable evidence regardingthe effectiveness of Chinese medicine, including Chuna manual therapy, for treating knee osteoarthritis. However, our systematic review had several limitations owingto the low quality of original articles andadditionalclinical trials would be necessary for stronger evidence.

Bee Venom Acupuncture for Shoulder Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials

  • Shen, Lei;Lee, Jong Ha;Joo, Jong Cheon;Park, Soo Jung;Song, Yung Sun
    • 대한약침학회지
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    • 제23권2호
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    • pp.44-53
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    • 2020
  • Objectives: Our review aimed to summarize and evaluate evidence on the effectiveness of bee venom acupuncture (BVA) in the treatment of shoulder pain. Methods: Randomized controlled trials (RCTs) evaluating the effectiveness of BVA on shoulder pain were searched up to October 2019 in 11 electronic databases (Medline, Embase, CENTRAL, CiNii, CNKI, VIP, Wanfang, Kmbase, NDSL, RISS, OASIS). The methodological quality of the included RCTs were evaluated using Cochrane Risk of Bias tool and a meta-analysis was performed. Results: Seven studies were included in the review, and four studies were included in the meta-analysis. Comparing BVA plus conventional therapy (CT) with saline injection plus CT, it showed an effect in favor of BVA plus CT in visual analog scale (VAS) and pain rating scale (PRS) (p = 0.02, p = 0.009, respectively). Comparing BVA plus physiotherapy (PT) with saline injection plus PT, it showed that there was no significant difference in VAS and verbal rating scale (VRS) between the two groups. Conclusion: This systematic review and meta-analysis suggest that BVA could be beneficial as an adjuvant treatment for shoulder pain.

산후 유즙분비부전에 대한 침 치료 효과 : 체계적 문헌 고찰 (The Clinical Effect on Acupuncture Treatment of Postpartum Hypogalactia: A Systematic Review of Randomized Controlled Trials)

  • 김유정;박경선;황덕상;이진무;장준복;이창훈
    • 대한한방부인과학회지
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    • 제30권3호
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    • pp.79-91
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    • 2017
  • Objectives: The purpose of this systematic review is to overview and evaluate the effect on postpartum hypogalactia after acupuncture treatment. Methods: Relevant randomized controlled trials (RCTs) were identified by database searches in Embase, Pubmed, CENTRAL, CNKI, KISS. Searching keywords were "Hypogalactia" or "Hypolactaion" and "Acupuncture". After searching qualified articles, we independently assessed the risk of bias according to the Cochrane Rob criteria. Results: Among the 81 articles five RCTs were finally selected. Four of the selected were statistically significant. One of them was not statistically significant because it was comparative study of chinese medicine and acupuncture treatment. The quality of the evidence for specific comparisons ranged from low to high. Conclusions: Our systematic review found encouraging. Acupuncture treatment would be effective way to increase insufficient milk supply on postpartum hypogalactia.

한포진 치료의 중의학 임상연구 동향 - 무작위 대조군 임상연구를 중심으로 - (An Overview of Clinical Studies for Pompholyx in Traditional Chinese Medicine - Literature Review based on Randomized Controlled Trials -)

  • 우정아;박범찬;최일신;김기봉;천진홍
    • 대한한방소아과학회지
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    • 제35권4호
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    • pp.82-95
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    • 2021
  • Objectives The purpose of this study is to analyze clinical studies on the effectiveness of TCM (traditional Chinese medicine) for pompholyx treatment and provide evidence for Korean medicine use. Methods Randomized controlled trials (RCT) which used TCM as a treatment for pompholyx were searched in China National Infrastructure (CNKI) platform. The risk of bias of studies was assessed by using Cochrane risk of bias (RoB) 2.0 tool. Results The selected 10 RCTs showed that the experimental group treated with either TCM alone or with a combination of TCM and Western medicine showed more significant therapeutic effect compared to the control group which Western medicine alone. Conclusions Based on the studies from China, TCM may be an effective treatment for pompholyx. This provides evidence for Korean medicine use, and its possible effectiveness in treating pompholyx

Oseltamivir를 투약한 양성대조군과 비교한 인플루엔자의 한약 치료 효과 - RCT 연구를 중심으로 - (Review of Clinical Research for Herbal Medicine in the Treatment of Influenza Compared with Oseltamivir)

  • 장은하;민상연;김장현
    • 대한한방소아과학회지
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    • 제33권3호
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    • pp.1-14
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    • 2019
  • Objectives The purpose of this study is to analyze clinical studies on effectiveness of herbal medicine in influenza compared with Oseltamivir. Methods We searched the randomized controlled trials (RCTs) with herbal medicine treatment on influenza compared to Oseltamivir from the Pubmed, CNKI, OASIS, NDSL, J-stage, and CiNii. Results 14 out of 717 studies were selected and analyzed. The herbal medicine treatment had a significant effects on the alleviation of fever, cough, sore throat than the Oseltamivir control treatment. Herbal medicine had same therapeutic effectiveness like Oseltamivir on duration of influenza-like symptoms and viral shedding. No serious adverse reactions were reported from the herbal medicine treatment. Conclusions The results of these trials showed that the herbal medicine may be more effective than the Oseltamivir in the treatment of influenza. Well-designed RCTs for domestic herbal medicine treatment on influenza are needed to prove its efficacy clearly.

Pubmed로 검색한 주의력결핍-과잉행동장애 환아의 뉴로피드백 효과에 관한 문헌고찰 (Effectiveness of Neurofeedback Therapy in Attention Deficit/Hyperactivity Disorders)

  • 장석주;김장현;민상연
    • 대한한방소아과학회지
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    • 제33권2호
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    • pp.69-83
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    • 2019
  • Objectives The purpose of this study is to review the effectivenss of Neurofeedback Therapy in children with Attention Deficit/Hyperactivity Disorders Methods 16 randomized controlled trials (RCT) of Neurofeedback Treatment in ADHD from 2009 to 2019 in PubMed were reviewed and analyzed their methods of assessment, treatment, results and adverse effect. Results In 16 RCT, the most frequently used diagnostic tool in ADHD was DSM-IV. Most of the studies reported Neurofeedback Treatment isn't superior than placebo or medication group but still effective in ADHD. In 6 out of the 16 studies, there were no adverse effect reported. Conclusion Most of the studies have shown neurofeedback treatment was effective in ADHD symptoms. More clinical studies are needed to prove the effectiveness of neurofeedback in ADHD.

Comparing neuromodulation modalities involving the suprascapular nerve in chronic refractory shoulder pain: retrospective case series and literature review

  • Dey, Saugat
    • Clinics in Shoulder and Elbow
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    • 제24권1호
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    • pp.36-41
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    • 2021
  • Chronic shoulder pain not relieved by either conservative or surgical management is referred to as chronic refractory shoulder pain. This is a retrospective case series where chronic refractory shoulder pain patients were treated either with peripheral nerve stimulation (PNS) or with pulsed radiofrequency (p-RF) therapy to the suprascapular nerve. Both patients receiving PNS reported 100% pain relief for the first month. At the 3- and 6-month follow-ups, one patient continued to experience 100% relief while the other reported 90% relief. One patient undergoing p-RF experienced about 90% pain relief at both 1- and 3-month intervals and 0% relief at the 6-month interval. The other patient with p-RF experienced 33% relief at 1-month and 0% relief thereafter. No patient reported any complications. The results of previous randomized controlled trials evaluating the efficacy of p-RF administered to the suprascapular nerve were mixed, and there is a lack of published studies on PNS effects. Neuromodulation of the suprascapular nerve can be effective for chronic refractory shoulder pain patients. Larger scale randomized controlled trials comparing PNS and p-RF are needed to better understand their respective therapeutic capacity.