• KIPS Transactions on Software and Data Engineering
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• v.3 no.10
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• pp.421-428
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• 2014

Like Alzheimer's disease, Parkinson's Disease(PD) is one of the most common neurodegenerative brain disorders. PD results from the deterioration of dopaminergic neurons in the brain region called the substantia nigra. Currently there is no cure for PD, but diagnosing in its early stage is important to provide treatments for relieving the symptoms and maintaining quality of life. Unlike many diagnosis methods of PD which use a single biomarker, we developed a diagnosis method that uses both biochemical biomarkers and imaging biomarkers. Our method uses ${\alpha}$-synuclein protein levels in the cerebrospinal fluid and diffusion tensor images(DTI). It achieved an accuracy over 91.3% in the 10-fold cross validation, and the best accuracy of 72% in an independent testing, which suggests a possibility for early detection of PD. We also analyzed the characteristics of the brain fiber pathways of Parkinson's disease patients and normal elderly people.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38B no.2
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• pp.97-104
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• 2013

This paper introduces waiting time based periodic packet discard policy for frame based scheduler. This policy can be used with conventional packet discard policy or buffer management schemes, such as drop-tail or random early detection. Proposed discard policy discards packets, which are stayed in the buffer longer than threshold, at every period of scheduling. This decision of discard is based on waiting time of packet. In this paper, mathematical analysis is performed with situation of network congestion. Also, the simulation is performed to evaluate the performance of proposed discard policy. In the result, proposed discard policy can limit queuing delay by threshold. Also, if the packet discard is performed before scheduling and threshold is set with smaller value than frame length, it can limit the throughput of traffic.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.6A
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• pp.667-667
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• 2004

We must design the buffer algorithm that protects traffic congestion and decreasing throughput at satellite communication network. It is important that buffer algorithm is satisfied with the good performance of transmission packet, responsibility of many connecting traffic and the QOS for connecting character. Old buffer algorithms are not the suitable algorithms when we have the satellite communication network environment. RED buffer algorithm is proposed by Floyd. It has a better performance than old buffer algorithm. But this algorithm is not well adapted a number of connecting TCP packet and changing network, so this algorithm has a bad performance on satellite communication network that is many of connecting user at same time. This paper propose the TARED(Target Adaptive RED). It has a good performance, adaptation and stability on satellite communication network and has not overflow and underflow of the buffer level.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.6A
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• pp.666-676
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• 2004

We must design the buffer algorithm that protects traffic congestion and decreasing throughput at satellite communication network. It is important that buffer algorithm is satisfied with the good performance of transmission packet, responsibility of many connecting traffic and the 005 for connecting character. Old buffer algorithms are not the suitable algorithms when we have the satellite communication network environment. RED buffer algorithm is proposed by Floyd. It has a better performance than old buffer algorithm. But this algorithm is not well adapted a number of connecting TCP packet and changing network, so this algorithm has a bad Performance on satellite communication network that is many of connecting user at same time. This paper Propose the TARED(Target Adaptive RED). It has a good performance, adaptation and stability on satellite communication network and has not overflow and underflow of the buffer level.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8479-8486
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• 2016

Background: Colorectal cancer (CRC) is the third most common cancer globally. In Jordan, it is the number one cancer among men and the second most common cancer among women, accounting for 15% and 9.4% respectively of all male and female diagnosed cancers. This study aimed to evaluate the knowledge and perceptions about colorectal cancer risk factors, signs and symptoms in Jordan and to provide useful data about the best modes of disseminating preventive messages about the disease. Materials and Methods: A stratified clustered random sampling technique was used to recruit 300 males and 300 females aged 30 to 65 years without a previous history of CRC from four governorates in Jordan. A semi-structured questionnaire and face to face interviews were employed. Descriptive and multivariate analysis was applied to assess knowledge and perceptions about CRC. Results: Both males and females perceived their CRC risk to be low. They had low knowledge scores about CRC with no significant gender association (P=0.47). From a maximum knowledge score of 18 points, the median scores of males and females were 4 points (SD=2.346, range 0-13) and 4 points (SD=2.329, range 0-11) respectively. Better knowledge scores were associated with governorate, higher educational level, older age, higher income, having a chronic disease, having a family history of CRC, previously knowing someone who had CRC and their doctor's knowledge about their family history of CRC. Conclusions: There is a low level of knowledge about CRC and underestimation of risk among the study participants. This underlines the need for public health interventions to create awareness about the illness. It also calls for further research to assess the knowledge and perceptions about CRC early detection examinations in Jordan.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1083-1088
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• 2016

Background: Cervical cancer is the second commonest cancer among Indian women and its association with human papilloma virus (HPV) is well established. This preventable cancer accounts for the maximum number of cancer related deaths among rural Indian women. Unlike in developed countries there are no organized cervical cancer screening programmes in India due to lack of resources and manpower. Objective: To detect genital HPV infection using urine samples among asymptomatic rural women in the age group of 18-65 years. Materials and Methods: The study area chosen was Perdoor village in Udupi Taluk, Karnataka State and all the women in the age group of 18-65 years formed the study cohort. A cross sectional study was conducted by house visits and 1,305 women were enrolled in the study. After taking written informed consent a data sheet was filled and early stream random urine samples were collected, transported to a laboratory at 4OC and aliquoted. Samples were tested using nested HPV PCR with PGMY09/11 and GP5+/6+ primers. Positive cases were genotyped by sequence analysis. Results: Study participants included 1,134 sexually active and 171 unmarried women with a mean age at marriage of 22.1 (SD=3.9) years. Study area showed high female literacy rate of 86.6%. Five urine samples tested positive for HPV DNA (0.4%). Conclusions: We found very low genital HPV infection rate among women from monogamous community. This is the first major population based study carried out among asymptomatic rural women to detect genital HPV infectio from Karnataka using urine samples.

• Clinical and Experimental Pediatrics
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• v.63 no.2
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• pp.34-43
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• 2020

Phenylketonuria is a disease caused by congenital defects in phenylalanine metabolism that leads to irreversible nerve cell damage. However, its detection in the early days of life can reduce its severity. Thus, many countries have started disease screening programs for neonates. The present study aimed to determine the worldwide prevalence of classic phenylketonuria using the data of neonatal screening studies.The PubMed, Web of Sciences, Sciences Direct, ProQuest, and Scopus databases were searched for related articles. Article quality was evaluated using the Joanna Briggs Institute Critical Appraisal Evaluation Checklist. A random effect was used to calculate the pooled prevalence, and a phenylketonuria prevalence per 100,000 neonates was reported. A total of 53 studies with 119,152,905 participants conducted in 1964-2017 were included in this systematic review. The highest prevalence (38.13) was reported in Turkey, while the lowest (0.3) in Thailand. A total of 46 studies were entered into the meta-analysis for pooled prevalence estimation. The overall worldwide prevalence of the disease is 6.002 per 100,000 neonates (95% confidence interval, 5.07-6.93). The meta-regression test showed high heterogeneity in the worldwide disease prevalence (I²=99%). Heterogeneity in the worldwide prevalence of phenylketonuria is high, possibly due to differences in factors affecting the disease, such as consanguineous marriages and genetic reserves in different countries, study performance, diagnostic tests, cutoff points, and sample size.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.4C
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• pp.353-364
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• 2002

To prevent the performance degradation of TCP due to packet loss in the smooth handoff by the route optimization extension of Mobile If protocol, a buffering of packets at a base station is needed. A buffering of packets at a base station recovers the packets dropped during the handoff by forwarding the buffered packets at the old base station to the mobile user. But, when the mobile user moves to a new foreign network which is connected to a congested router, the buffered packets forwarded by the old base station are dropped and the link utilization performance degraded due to increased congestion by the forwarded packets. In this paper, when the mobile user moves to a new foreign network which is connected to a congested router, Ive propose a packet forwarding control scheme required far the old base station to improve TCP performance in mobile networks. The old base station forwards or discards the buffered packets during handoff by proposed packet forwarding control scheme based on congestion states of RED(Random Early Detection) at the congested router. Simulation results slow that link utilization performance can be improved by applying proposed packet forwarding control scheme.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.23 no.2
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• pp.76-81
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• 2012

Objectives : Childhood is a critical period involving various developmental tasks that need to be accomplished. Childhood depression has overall negative implications for certain areas of development, including cognition, emotion, social skills, academic achievement, and ability to cope with stress. Yet, because depression can be "masked" by accompanying behavioral problems, early detection and diagnosis of childhood depression is somewhat challenging. In this study, using the Korean version of the Child Behavior Checklist (K-CBCL), we evaluated the association between children's self reports on depression and parents' assessment of children's behaviors. Methods : Subjects were recruited from the S city, a cohort comprising a non-random convenience sample of 226, 10-year-old ethnic Koreans in their fourth year of elementary school and their parents. All participants underwent several tests, including Children's Depression Inventory (CDI) and K-CBCL. Results : A total of 226 children, including 166 boys (73.5%) and 60 girls (26.5%), participated in the study. The average CDI for the participants was 14.57 (SD=7.54). Two items on the K-CBCL, total scale of adjustment scale and social withdrawal problems, showed a close association with the CDI. Conclusion : Although much remains to be elucidated, after controlling for covariates, the results of this study suggested that behavioral problems observed in children may be closely associated with depression.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.45 no.5
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• pp.125-133
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• 2008

In this paper, we propose active queue management mechanism (Active-WRED) to guarantee quality of the high priority service class in multi-class traffic service environment. In congestion situation, this mechanism increases drop probability of low priority traffic and reduces the drop probability of the high priority traffic, therefore it can improve the quality of the high priority service. In order to analyze the performance of our mechanism we introduce the stochastic analysis of a discrete-time queueing systems for the performance evaluation of the Active Queue Management (AQM) based congestion control mechanism called Weighted Random Early Detection (WRED) using a two-state Markov-Modulated Bernoulli arrival process (MMBP-2) as the traffic source. A two-dimensional discrete-time Harkov chain is introduced to model the Active-WRED mechanism for two traffic classes (Guaranteed Service and Best Effort Service) where each dimension corresponds to a traffic class with its own parameters.