• 상하수도학회지
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• 제28권5호
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• pp.549-554
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• 2014

This study was evaluated the applicability of the membrane filtration process (Micro Filtration (MF), nanofiltration membranes (NF), reverse osmosis (RO)) on the major radioactive substances, iodine ($I^-$) and cesium ($Cs^+$) using membranes produced in Korea and domestic raw water. Iodine ($I^-$) or cesium ($Cs^+$) in the microfiltration membrane (MF) process could not be expected removal efficiency by eliminating marginally at the combined state with colloidal and turbidity material. At the domestic raw water (lake water, turbidity 1.2 NTU, DOC 1.3 mg/L) conditions, nanofiltration membrane (NF) and reverse osmosis (RO) showed a high removal rate of about 88 ~ 99% for iodine ($I^-$) and cesium ($Cs^+$) and likely to be an alternative process for the removal of radioactive material.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2005년도 Proceedings of The 6th korea-china joint workshop on nuclear waste management
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• pp.149-155
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• 2005

The $ACP^1$ is under development for effective management of spent fuel by converting $UO_2$ into U-metal. For demonstration of this process, $\alpha-\gamma$ type new hotcell was built in the $IMEF^2$ basement. To secure against radiation hazard, this facility needs radiation monitoring system which will observe the entire operating area before the hotcell and service area at back of it. This system consists of 7 parts; Area Monitor for $\gamma$-ray, Room Air Monitor for particulate and iodine in both area, Hotcell Monitor for hotcell inside high radiation and rear door interlock, Duct Monitor for particulate of outlet ventilation, Iodine Monitor for iodine of outlet duct, CCTV for watching workers and material movement, Server for management of whole monitoring system. After installation and test of this, radiation monitoring system will be expected to assist the successful ACP demonstration.

• 핵의학기술
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• 제18권1호
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• pp.149-152
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• 2014

핵의학과 영상검사 후에 검체검사를 시행할 경우 결과값에 미치는 영향을 알아보기 위해 PET-CT, Gated Myocardial SPECT, DTPA GFR Scan을 시행하기 전 후에 채혈하여 Tumor marker (AFP,CEA,CA19-9), Hormone (TSH,T3,TG,TG Ab)검사를 시행하여 Difference를 구하였다. 대부분의 결과가 10% 이내의 차이를 나타냈지만 Table 7의 sample 2와 Table 8의 sample 1, sample 6, sample 8의 저 농도 값에서 20%를 넘는 차이를 나타내는 경우가 있었다. 그렇지만 cpm값은 Table 7의 sample 2는 984(전), 1057(후) Table 8의 sample 1은 243(전), 301(후) sample 6은 58(전), 64(후) sample 8은 258(전), 203(후)으로 매우 흡사한 값을 나타냈다. 이 같은 값을 바탕으로 볼 때 영상검사를 시행한 후에 검체검사를 시행하더라도 결과값에 미치는 영향은 없는 것으로 판단된다.

• Nuclear Engineering and Technology
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• 제50권8호
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• pp.1355-1363
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• 2018

Many radionuclides exist in normal environment and artificial radionuclides also can be detected. The radionuclides ($^{131}I$) are widely used for labeling compounds and radiation therapy. In Korea, the radionuclide ($^{131}I$) is produced at the Radioisotope Production Facility (RIPF) at the Korea Atomic Energy Research Institute in Daejeon. The residents around the RIPF assume that $^{131}I$ detected in environmental samples is produced from RIPF. To ensure the safety of the residents, the radioactive concentration of $^{131}I$ near the RIPF was investigated by monitoring environmental samples along the Gap River. The selected geographical places are near the nuclear installation, another possible location for $^{131}I$ detection, and downstream of the Gap River. The first selected places are the "front gate of KAERI", and the "Donghwa bridge". The second selected place is the sewage treatment plant. Therefore, the Wonchon bridge is selected for the upstream of the plant and the sewage treatment plant is selected for the downstream of the plant. The last selected places are the downstream where the two paths converged, which is Yongshin bridge (in front of the cogeneration plant). In these places, environmental samples, including sediment, fish, surface water, and aquatic plants, were collected. In this study, the radioactive iodine ($^{131}I$) detection along the Gap River will be investigated.

• 대한핵의학회지
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• 제12권1호
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• pp.37-40
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• 1978

Carcinogen으로 알려져 있는 auflatoxine계통 화합물의 방사성 표지 반응을 연구하였다. Auflatoxine계통 약품중에서 그 함유량이 가장 큰 auflatoxin-$B_1$을 초산(醋酸) 촉매하에 chloroamine-T를 사용하여 $^{125}I$로 표지한 결과 표지화합물을 방사화학적 수율 63.6%로 얻을 수 있었다. 생성물의 화학구조를 I.R. 및 N.M.R.로 검사한 결과 auflatoxine의 benzene고리에 표지되었음을 확인하였다. 쥐를 시험동물로 삼아 경구 투여후의 대사과정을 부검(剖檢)으로 조사한 결과 간 및 혈액에 방사능이 축적되고 요오드이온은 분리되지 않았음을 확인하였다.

• 대한두경부종양학회지
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• 제14권1호
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• pp.61-69
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• 1998

Objectives: The response rate of the radioactive iodine(RI) therapy with low dose was variable. Only a few studies reported the response and complication rate with high dose. The goal of this study was to access the ablation and complication rate after high dose of RI therapy (more than 100mCi) and to evaluate the factors affect the results. Material and Methods: During a period of 12 years, 225 patients received high dose of RI from 100 to 200mCi depending on the RI uptake in the whole body after total thyroidectomy. 100mCi of RI was given to 123 patients for ablation who showed the uptake only in the thyroid bed. 150mCi was given to another 84 patients for ablation who had uptake confined to the neck. The other 21 patients took more than 200mCi of RI because the whole body scan showed distant metastasis. Among these patients, the ablation and the complication rate was investigated. Results: Elevated level of the serum thyroglobulin(Tg) decreased less than 5ng/ml after RI therapy in all patients except two in the first group. The second group showed reduction of the serum Tg in 93%. Eighteen of the 21 patients in the third group are still alive after RI therapy. There were no fatal complications after high dose RI therapy and most of the complications were minimal and transient. The complication rate was not related with the dose of RI, age, sex, DNA flowcytometry, serum thyroglobulin level and the extent of node dissection. Conclusion: We concluded that RI therapy with high dose was very effective for thyroid ablation after operation and it also showed excellent results with minimal complications for treatment of metastatic lesions.

• Journal of Yeungnam Medical Science
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• 제31권2호
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• pp.148-151
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• 2014

Radioactive iodine (RAI) therapy is widely used for the treatment of Graves disease. After RAI therapy, 44% become hypothyroid and up to 28% remain hyperthyroid. The development of thyrotoxicosis after RAI therapy is believed to be mediated by 2 different mechanisms: a transient increased release of thyroid hormone due to radiation thyroiditis and the rare development of Graves disease due to the formation of antibodies to the thyroid-associated antigens released from the damaged follicular cells. A 55-year-old woman was hospitalized with severe headache, weight loss, and palpitation. She received a dose of 7 mCi of RAI (I-131) about 6 weeks earlier. Thyroid function test showed 7.98 ng/dL free T4, >8 ng/mL T3, < $0.08{\mu}IU/L$ thyroid stimulating hormone, and high titer thyroid stimulating immunoglobulin (TSI) (85.8 IU/L). She improved with propylthiouracil, propranolol, and steroid treatment. The TSI, however, was persistently elevated for 11 months.

• 대한핵의학회지
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• 제9권1호
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• pp.59-71
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• 1975

53 patients with hyperthyroidism have been analyzed with special reference to therapeutic response to radioactive iodine ($^{131}I$) treatment. Mean effective half-life, 24 hour uptake rate and radiation dose of $^{131}I$ in hyperthyroid patients included in this study were respectively. 1. Mean effective half-life of $^{131}I\;was\;4.7{\pm}1.5$ days in the tracer dose and $5.0{\pm}1.5$ days in the therapeutic dose. 2. Mean 24 hour uptake rate of $^{131}I\;was\;72.7{\pm}11.1%$ in the tracer dose and $73.4{\pm}12.3%$ in the theapeutic dose. 3. Mean radiation dose of $^{131}I\;was\;5,319{\pm}2,648$ RAD as predicted and $5,692{\pm}2,843$ RAD as actual. A single dose of radioactive iodine treatment was satisfactory in 34 patients (radioiodine sensitive) and multiple doses of radioactive iodine treatments were required in 19 patients (radioiodine resistant). A radioiodine resistant group of patients with hyperthyroidism was distinctively characteristic in the following aspects. 1. Mean thyroid weight calculated in the resistant group ($63.9{\pm}14.0gm$) was significantly (p<0.01) greater than that of the sensitive group ($46.6{\pm}13.3gm$). 2. Mean 24 hour uptake rate of the tracer dose in the resistant group ($67.3{\pm}10.7%$) was significantly (p<0.01) lower than that of the sensitive group ($75.7{\pm}10.5%$). 3. Mean 24 hour uptake rate of the therapeutic dose in the resistant group ($68.5{\pm}13.7%$) was significantly (p<0.05) lower than that of the sensitive group ($76.1{\pm}10.9%$). 4. Mean predicted radiation dose, of $^{131}I$ in the resistant group ($3,684{\pm}1,745$ RAD) was significantly (p<0.01) lower than that of the sensitive group ($6,232{\pm}2,683$ RAD). 5. Mean actual radiation dose of $^{131}I$ in the resistant group ($4,100{\pm}1,691$ RAD) was significantly (p<0.01) lower than that of the sensitive group ($6,582{\pm}3,024$ RAD). 6. No significant difference was detected in terms of effective half-life of $^{131}I$ among the groups (p>0.05). 7. The average mean % difference of effective half-life, uptake rate and radiation dose measured following the tracer and therapeutic dose of $^{131}I$ were not statistically significant (p>0.05). Therefore effective half-life, uptake rate and radiation dose of the therapeutic dose of $^{131}I$ were readily predictable following the tracer dose of $^{131}I$. 8. It is concluded that the possibility of resistance to radioactive iodine treatment may be anticipated in patients with thyroid gland large in size and compromised $^{131}I$ uptake rate.

• 한국환경과학회지
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• 제24권9호
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• pp.1123-1129
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• 2015

This research was performed by means of several different virgin granular activated carbons (GAC) made of each coal, coconut and wood, and the GACs were investigated for an adsorption performance of iodine-131 in a continuous adsorption column. Breakthrough behavior was investigated that the breakthrough points of the virgin two coals-, coconut- and wood-based GACs were observed as bed volume (BV) 7080, BV 5640, BV 5064 and BV 3192, respectively. The experimental results of adsorption capacity (X/M) for iodine-127 showed that two coal- based GACs were highest (208.6 and $139.1{\mu}g/g$), the coconut-based GAC was intermediate ($86.5{\mu}g/g$) and the wood-based GAC was lowest ($54.5{\mu}g/g$). The X/M of the coal-based GACs was 2~4 times higher than the X/M of the coconut-based and wood-based GACs.

• 대한핵의학회지
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• 제3권1호
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• pp.101-105
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• 1969

A case of lingual thyroid in 10 years old girl is presented with the use of radioactive iodine ($^{113}I$) and the scintigram for the diagnostic evaluation. A brief review of literature on the incidence, etiology and-development, symptomatology, diagnosis, and treatment of the lingual thyroid was done.