• Economic and Environmental Geology
• /
• v.33 no.3
• /
• pp.195-204
• /
• 2000

order to investigate physical characteristics and element concentrations of sediments, coastal bottom sediments were collected at 20 stations in the vicinity of Youngkwang Nuclear Power Plant. After air drying of samples in the laboratory. article size distribution was examined by Master sizer (X-350F), radio-activity by HPGe ${\gamma}$-spectrphotometer, and element concentrations by ICP-AES and AAS. According to particle size analysis , sediments are mainly composed of silt fraction weith 23% of sand, 65% of silt and 12% of clay on average. Most sediments are derived from muddy environment that silt dominates with the characteristics of 5.3${\varsigma}$ mean particle size, poorly sorted, very fine skewed and lepto-kurtic. Only two sediments are well sorted with sandy silt owing to wind, winnowing action, tide and current andits complex reactions. Element concentrations in the coastal bottom sediments are relatively high at finer sediment and show significant relationship with grain size. Index of geoaccumulation by heavy metals at every sampling station is classified as practically unpolluted. The radioactivities of the sediments were measured for 15 isotope elements, and 2 elements of K-40 and Cs-137 were detected in most sediments. The K-40 is the natural nuclide and the artificial nuclide of Cs-137 was thought to be derived from the fallout of past nuclear weapon test. The results of correlation coefficient between grain size and radioactivity shows that the activity of Cs-137 significantly increases in finer grain.

• Nuclear Engineering and Technology
• /
• v.45 no.1
• /
• pp.61-66
• /
• 2013

Among the radioactive wastes generated from the nuclear power plant, a radioactive nuclide such as $^{129}I$ is classified as a difficult-to-measure (DTM) nuclide, owing to its low specific activity. Therefore, the establishment of an analytical procedure, including a chemical separation for $^{129}I$ as a representative DTM, becomes essential. In this report, the adsorption and recovery rate were measured by adding $^{125}I$ as a radio-isotopic tracer ($t_{1/2}$ = 60.14 d) to the simulation sample, in order to measure the activity concentration of $^{129}I$ in a pressurized-water reactor primary coolant. The optimum condition for the maximum recovery yield of iodine on the anion exchange resins (AG1 x2, 50-100 mesh, $Cl^-$ form) was found to be at pH 7. In this report, the effect of the boron content in a pressurized-water reactor primary coolant on the separation process of $^{129}I$ was examined, as was the effect of $^3H$ on the measurement of the activity of iodine. As a result, no influence of the boron content and of the simultaneous $^3H$ presence was found with activity concentrations of $^3H$ lower than 50 Bq/mL, and with a boron concentration of less than 2,000 ${\mu}g/mL$.

• Journal of Radiation Protection and Research
• /
• v.47 no.4
• /
• pp.237-245
• /
• 2022

Background: The current study reports measurements of activity concentrations of radon (²²⁰Rn) and thoron (²²⁰Rn) in dwellings, followed by inhalation dose assessment of the public, and then by the development of regulation and the national radon action plan (NRAP) in Cameroon. Materials and Methods: Radon, thoron, and thoron progeny measurements were carried out from 2014 to 2017 using radon-thoron discriminative detectors (commercially RADUET) in 450 dwellings and thoron progeny monitors in 350 dwellings. From 2019 to 2020, radon track detectors (commercially RADTRAK) were deployed in 1,400 dwellings. It was found that activity concentrations of radon range in 1,850 houses from 10 to 2,620 Bq/㎥ with a geometric mean of 76 Bq/㎥. Results and Discussion: Activity concentrations of thoron range from 20 to 700 Bq/㎥ with a geometric mean of 107 Bq/㎥. Thoron equilibrium factor ranges from 0.01 to 0.6, with an arithmetic mean of 0.09 that is higher than the default value of 0.02 given by UNSCEAR. On average, 49%, 9%, and 2% of all surveyed houses have radon concentrations above 100, 200, and 300 Bq/㎥, respectively. The average contribution of thoron to the inhalation dose due to radon and thoron exposure is about 40%. Thus, thoron cannot be neglected in dose assessment to avoid biased results in radio-epidemiological studies. Only radon was considered in the drafted regulation and in the NRAP adopted in October 2020. Reference levels of 300 Bq/㎥ and 1,000 Bq/㎥ were recommended for dwellings and workplaces. Conclusion: Priority actions for the coming years include the following: radon risk mapping, promotion of a protection policy against radon in buildings, integration of the radon prevention and mitigation into the training of construction specialists, mitigation of dwellings and workplaces with high radon levels, increased public awareness of the health risks associated with radon, and development of programs on the scientific and technical aspects.

• Archives of Pharmacal Research
• /
• v.11 no.2
• /
• pp.93-98
• /
• 1988

To elucidate the reaction mechanism of ginseng protein on its antiradiation activity, its effects were studied on sister chromatid exchanges (SCE) induced by UV irradiation in CHO-KI cells. When cells were irradiated with 254 nm UV light at the dose of 0 to 8erg$\textrm{mm}^2$, the frequencies of CSE were increased more than two fold. However, when radio protective ginseng protein was added to the cells before the after UV irradiation, SCE frequencies were decreased significantly at all UV doses in both cases with no significant differences. As the amount of ginseng protein was varied from 100 to 500 .mu.g/ml, with UV irradiation at 60 erg$\textrm{mm}^2$, SCE frequencies dropped sharply at the first two concentrations and then reached a sort of plateau in both cases of pre-and post-treatment. When the ginseng protein was treated alone without UV irradiation, there were no changes in SCE frequencies no matter when the protein was added. There results suggest that the ginseng protein could reduced DNA damages, which may play an important role in the reaction mechanism of radioprotective activity of the protein.

• Journal of Radiation Industry
• /
• v.5 no.1
• /
• pp.15-20
• /
• 2011

Protein kinases are the most important drug targets for the treatment of numerous diseases. The involvement of protein kinase C (PKC) in many biological processes such as development, memory, cell differentiation, and proliferation has been demonstrated. PKC is recognized as an important player in carcinogenesis. Thus, a variety of PKC inhibitors have been investigated. Among them, flavonoids have been demonstrated to affect the activity of many mammalian in vitro enzyme systems. The recent investigation was performed to evaluate the inhibitory effects of hesperidin, which is a flavonoid, on the proliferation and carcinogenesis of many cancers. In this study, an efficient kinase assay based on a biochip using radio-phosphorylation was established and performed for an examination of the inhibitory effects of hesperidin on PKC activity at different concentrations of 50, 200, 500 nM. It was found that hesperidin shows inhibitory potency on PKC, and that the biochip can be used to rapidly screen kinase inhibitors resulting in the therapeutic agents.

• Journal of Radiation Protection and Research
• /
• v.19 no.3
• /
• pp.179-188
• /
• 1994

Mice were whole body irradiated with dose of 2.88Gy and 7.2Gy(Co-60) in order to observe the morphological and functional changes in radio sensitive mouse ovary. Microtechnical sectionates of $7{\mu}m$ thickness from ovary were made for light microscopy and concentrations of progesterone, testosterone and estradiol in ovarian homogenates were analyzed by radioimmunoassay. Gamma radiation resulted in the increase of atretic ratio of preantral and antral follicles, the increase of progesterone concentration in ovarian homogenates, and the low level of testosterone and estradiol. It is suggested that radiation protect the activity of $3{\beta}-HSD$(hydroxysteroid dehydrogenase) and isomerase in the follicular theca cell followed by low level of testosterone and estradiol and thereafter follicular atresia proceed.

• Journal of the korean society of oceanography
• /
• v.35 no.1
• /
• pp.16-33
• /
• 2000

In order to measure the vertical fluxes of particles and reactive radionuclides such as thorium and polonium isotopes, Dunbar-type sediment traps were freely deployed at the Ulleung Basin and in warm and cold water masses around the polar front of the East Sea. We estimated the ratios of the catched (F) to the predicted $^234$Th fluxes (P) using natural tracers pair $^234$Th-$^238$U. The F/P ratios are decreased with increasing water depth. Whereas the concentrations of suspended particles are homogeneous in water column, the mass fluxes are also decreased with increasing water depth like the F/P ratios. These facts indicate that organic matters of settling particles are destructed within the euphotic layer due to decomposition. Whereas regenerations of sinking particles are negligible in the cold water mass, about 80% of them are regenerated in the warm water mass during falling of large particles. These downward mass fluxes are closely correlated with their primary productions in euphotic zone. The activities of $^234$Th, $^228$Th and $^210$Po in the sinking material were increased with water depth. Because $^234$Th steadily produced in the water column are cumulatively adsorbed on the surface of sinking particles, vertical $^234$Th fluxes were observed to increase with water depth. Therefore, these sinking particles play important roles in transporting the particle reactive elements like thorium from surface to the deep sea. The scavenging processes including adsorption and settling reactions generate radio-disequilibrium between daughter and parent nuclides in water column. The activity ratios of $^234$Th/$^238$U and $^228$Th/$^228$Ra were observed to be < 1.0 in the surface water and approached to be equilibrium below the thermocline. The extent of the deficiency of daughter nuclides compared to the parents nuclide was highly correlated with the vertical particle flux. Because most of the $^210$Po in the surface water are scavenged on a labile phase and are recycled at sub-surface depths (< 200 m), the $^210$Po are always observed to be excess activities compared to $^226$Ra in surface water.

• The Korean Journal of Nuclear Medicine Technology
• /
• v.14 no.2
• /
• pp.172-176
• /
• 2010

Purpose: The patients' moves occurred at PET/CT scan will cause the decline of correctness in results by resulting in inconsistency of Attenuation Correction (AC) and effecting on quantitative evaluation. This study has evaluated the utility of reconstruction method using AC position changing method when having inconsistency of AC depending on the position change of emission scan after transmission scan in obtaining PET/CT 3D image. Materials and Methods: We created 1 mL syringe injection space up to ${\pm}2$, 6, 10 cm toward x and y axis based on central point of polystyrene ($20{\times}20110$ cm) into GE Discovery STE16 equipment. After projection of syringe with $^{18}F$-FDG 5 kBq/mL, made an emission by changing the position and obtained the image by using AC depending on the position change. Reconstruction method is an iteration reconstruction method and is applied two times of iteration and 20 of subset, and for every emission data, decay correction depending on time pass is applied. Also, after setting ROI to the position of syringe, compared %Difference (%D) at each position to radioactivity concentrations (kBq/mL) and central point. Results: Radioactivity concentrations of central point of emission scan is 2.30 kBq/mL and is indicated as 1.95, 1.82 and 1.75 kBq/mL, relatively for +x axis, as 2.07, 1.75 and 1.65 kBq/mL for -x axis, as 2.07, 1.87 and 1.90 kBq/mL for +y axis and as 2.17, 1.85 and 1.67 kBq/mL for -y axis. Also, %D is yield as 15, 20, 23% for +x axis, as 9, 23, 28% for -x axis, as 12, 21, 20% for +y axis and as 8, 22, 29% for -y axis. When using AC position changing method, it is indicated as 2.00, 1.95 and 1.80 kBq/mL, relatively for +x axis, as 2.25, 2.15 and 1.90 kBq/mL for -x axis, as 2.07, 1.90 and 1.90 kBq/mL for +y axis, and as 2.10, 2.02, and 1.72 kBq/mL for -y axis. Also, %D is yield as 13, 15, 21% for +x axis, as 2, 6, 17% for -x axis, as 9, 17, 17% for +y axis, and as 8, 12, 25% for -y axis. Conclusion: When in inconsistency of AC, radioactivity concentrations for using AC position changing method increased average of 0.14, 0.03 kBq/mL at x, y axis and %D was improved 6.1, 4.2%. Also, it is indicated that the more far from the central point and the further position from the central point under the features that spatial resolution is lowered, the higher in lowering of radioactivity concentrations. However, since in actual clinic, attenuation degree increases more, it is considered that when in inconsistency, such tolerance will be increased. Therefore, at the lesion of the part where AC is not inconsistent, the tolerance of radioactivity concentrations will be reduced by applying AC position changing method.

• The Korean Journal of Nuclear Medicine Technology
• /
• v.16 no.1
• /
• pp.102-107
• /
• 2012

Purpose : Because of the rapid physical decay of the short half-lived radionuclide, counting of event for image is very limited. In this reason, long scan duration is applied for more accurate quantitative analysis in the relatively low sensitive examination. The aim of this study was to evaluate the difference according to scan duration and investigate the resonable scan duration using the radionuclide of 11C and 18F in PET scan. Materials and Methods : 1994-NEMA Phantom was filled with 11C of $30.08{\pm}4.22MBq$ and 18F of $40.08{\pm}8.29MBq$ diluted with distilled water. Dynamic images were acquired 20frames/1minute and static image was acquired for 20minutes with 11C. And dynamic images were acquired 20frames/2.5minutes and static image was acquired for 50minutes with 18F. All of data were applied with same reconstruction method and time decay correction. Region of interest (ROI) was set on the image, maximum radioactivity concentration (maxRC, kBq/mL) was compared. We compared maxRC with acquired dynamic image which was summed one bye one to increase the total scan duration. Results : maxRC over time of 11C was $3.85{\pm}0.45{\sim}5.15{\pm}0.50kBq/mL$ in dynamic image, and static image was $2.15{\pm}0.26kBq/mL$. In case of 18F, the maxRC was $9.09{\pm}0.42{\sim}9.48{\pm}0.31kBq/mL$ in dynamic image and $7.24{\pm}0.14kBq/mL$ in static. In summed image of 11C, as total scan duration was increased to 5, 10, 15, 20minutes, the maxRC were $2.47{\pm}0.4$, $2.22{\pm}0.37$, $2.08{\pm}0.42$, $1.95{\pm}0.55kBq/mL$ respectively. In case of 18F, the total scan duration was increased to 12.5, 25, 37.5, and 50minutes, the maxRC were $7.89{\pm}0.27$, $7.61{\pm}0.23$, $7.36{\pm}0.21$, $7.31{\pm}0.23kBq/mL$. Conclusion : As elapsed time was increased after completion of injection, the maxRC was increased by 33% and 4% in dynamic study of 11C and 18F respectively. Also the total scan duration was increased, the maxRC was reduced by 50% and 20% in summed image of 11C and 18F respectively. The percentage difference of each result is more larger in study using relatively shorter half-lived radionuclide. It appears that the accuracy of decay correction declined not only increment of scan duration but also increment of elapsed time from a starting point of acquisition. In study using 18F, there was no big difference so it's not necessary to consider error of quantitative evaluation according to elapsed time. It's recommended to apply additional decay correction method considering decay correction the error concerning elapsed time or to set the scan duration of static image less than 5minutes corresponding 25% of half life in study using shorter half-lived radionuclide as 11C.