• Radiation Oncology Journal
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• v.37 no.4
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• pp.279-285
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• 2019

Purpose: This study was conducted to compare the outcome of three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) for the postoperative treatment of biliary tract cancer. Materials and Methods: From February 2008 to June 2016, 57 patients of biliary tract cancer treated with curative surgery followed by postoperative 3D-CRT (n = 27) or IMRT (n = 30) were retrospectively enrolled. Results: Median follow-up time was 23.6 months (range, 5.2 to 97.6 months) for all patients and 38.4 months (range, 27.0 to 89.2 months) for survivors. Two-year recurrence-free survival is higher in IMRT arm than 3D-CRT arm with a marginal significance (25.9% vs. 47.4%; p = 0.088). Locoregional recurrence-free survival (64.3% vs. 81.7%; p = 0.122) and distant metastasis-free survival (40.3% vs. 55.8%; p = 0.234) at two years did not show any statistical difference between two radiation modalities. In the multivariate analysis, extrahepatic cholangiocarcinoma, poorly-differentiated histologic grade, and higher stage were significant poor prognostic factors for survival. Severe treatment-related toxicity was not significantly different between two arms. Conclusions: IMRT showed comparable results with 3D-CRT in terms of recurrence, and survival, and radiotherapy toxicity for the postoperative treatment of biliary tract cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3365-3370
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• 2015

Radiotherapy has an important role in the treatment of prostate cancer. Three-dimensional conformal radiation therapy (3D-CRT), intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) techniques are all applied for this purpose. However, the risk of secondary radiation-induced bladder cancer is significantly elevated in irradiated patients compared surgery-only or watchful waiting groups. There are also reports of risk of secondary cancer with low doses to normal tissues. This study was designed to compare received volumes of low doses among 3D-CRT, IMRT and VMAT techniques for prostate patients. Ten prostate cancer patients were selected retrospectively for this planning study. Treatment plans were generated using 3D-CRT, IMRT and VMAT techniques. Conformity index (CI), homogenity index (HI), receiving 5 Gy of the volume (V5%), receiving 2 Gy of the volume (V2%), receiving 1 Gy of the volume (V1%) and monitor units (MUs) were compared. This study confirms that VMAT has slightly better CI while thev olume of low doses was higher. VMAT had lower MUs than IMRT. 3D-CRT had the lowest MU, CI and HI. If target coverage and normal tissue sparing are comparable between different treatment techniques, the risk of second malignancy should be a important factor in the selection of treatment.

• Radiation Oncology Journal
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• v.38 no.1
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• pp.11-17
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• 2020

Purpose: Definitive radiotherapy remains a primary treatment option for early stage glottic cancer. Intensity-modulated radiation therapy (IMRT) has emerged as the standard treatment technique for advanced head and neck cancers, whereas three-dimensional conformal radiotherapy (3D-CRT) has remained standard for early glottic cancers. We used the National Cancer Database (NCDB) to identify predictors of IMRT use and effect on outcome in these patients. Materials and Methods: We queried the NCDB from 2004-2015 for squamous cell carcinoma of the glottic larynx staged Tis-T2N0 treated with radiation alone. Logistic regression was used to identify predictors of IMRT. Cox regression was used to identify factors predictive of overall survival. Propensity matching was conducted to account for indication bias. Results: We identified 15,627 patients, of which 11% received IMRT. IMRT use rose from 2% in 2004 to 16% in 2015. Predictors of IMRT include: increased comorbidity, T2 stage, urban location, chemotherapy, treatment at an academic center, and later treatment year. Predictors of improved survival were female gender, higher income, lower stage, no chemotherapy, academic facility, and more remote year. There was no difference in survival between 3D-CRT and IMRT across all stages. Conclusions: The rate of IMRT use for early stage glottic laryngeal cancer has increased over time. There was no difference in outcome in patients receiving IMRT versus 3D-CRT across the cohort.

• The Journal of the Acoustical Society of Korea
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• v.4 no.2
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• pp.3-12
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• 1985

The surface intensity method is a relatively new tool which can identify the noise source or path and measure the radiation power. One microphone and one accelerometer are used in this new technique. In this study, this new technique has been used to measure the field transmission loss trough doors. The results of the experiment indicate that the surface intensity method produces reliable data and can be applied to the transmission loss measurement.

• The Journal of the Acoustical Society of Korea
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• v.4 no.2
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• pp.3.1-3.1
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• 1985

The surface intensity method is a relatively new tool which can identify the noise source or path and measure the radiation power. One microphone and one accelerometer are used in this new technique. In this study, this new technique has been used to measure the field transmission loss trough doors. The results of the experiment indicate that the surface intensity method produces reliable data and can be applied to the transmission loss measurement.

• The Korean Journal of Food & Health Convergence
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• v.4 no.3
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• pp.1-5
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• 2018

In today's technological development of human society more and more influence on the lives of biological organisms different electromagnetic radiation. Therefore, the study and analysis of the mechanisms of their effects is an urgent task. The purpose of research - the study of the primary mechanisms of interaction of photons of optical radiation with the structures of biological objects, using the laws of quantum mechanics and biophysics. Photobiological basis of the mechanism of action of EMR optical range is the energy absorption of light quanta (photons) by atoms and molecules of biological structures (law Grotgus-Draper), which resulted in the formation of electronically excited states of these molecules with the transfer of photon energy (internal photoeffect). This is accompanied by electrolytic dissociation and ionization of biological molecules. The degree of manifestation of photobiological effects in the body depends on the intensity of the optical radiation, which is inversely proportional to the square of the distance from the source to the irradiated surface. Accordingly, in practice, determine not the intensity and irradiation dose at a certain distance from the source of exposure by the exposure time.

• Radiation Oncology Journal
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• v.37 no.4
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• pp.271-278
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• 2019

Purpose: To investigate the differences in treatment outcomes between two radiation techniques, intensity-modulated radiotherapy (IMRT) and three-dimensional conformal radiotherapy (3DCRT). Materials and Methods: We retrospectively analyzed 160 (IMRT = 23, 3DCRT = 137) patients with stage I glottic cancer treated from January 2005 through December 2016. The IMRT was performed with TomoTherapy (16 patients), volumetric-modulated arc therapy (6 patients), and step-and-shoot technique (1 patient), respectively. The 3DCRT was performed with bilateral parallel opposing fields. The median follow-up duration was 30 months (range, 31 to 42 months) in the IMRT group and 65 months (range, 20 to 143 months) in the 3DCRT group. Results: The 5-year overall survival and 3-year local control rates of the 160 patients were 95.7% and 91.4%, respectively. There was no significant difference in 3-year local control rates between the IMRT and 3DCRT groups (94.4% vs. 91.0%; p = 0.587). Thirteen of 137 patients in the 3DCRT group had recurrences. In the IMRT group, one patient had a recurrence at the true vocal cord. Patients treated with IMRT had less grade 2 skin reaction than the 3DCRT group, but this had no statistical significance (4.3% vs. 21.2%; p = 0.080). Conclusion: IMRT had comparable outcomes with 3DCRT, and a trend of less acute skin reaction in stage I glottic cancer patients.

• 대한두경부종양학회:학술대회논문집
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• 2004.11a
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• pp.258-258
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• 2004

• Journal of the Korean Society of Safety
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• v.22 no.1 s.79
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• pp.24-29
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• 2007

The effectiveness of a UV(ultra violet) disinfection system depends on the characteristics of the waste water, flow conditions, the intensity of UV radiation, the amount of time the microorganisms are exposed to the radiation, and the reactor configuration. The wast water flow conditions are important factors in the design of UV disinfection system from the point of enhancement view of UV disinfection. The turbulent energy intensity in the wake by the vortex shedding are effective for UV radiation. Therewith the effectiveness of vortex generator is considered as a enhancement of UV disinfection. The experimental results presented give important evidences and explain that it is possible to predict UV disinfection performance based on flow experiments. An experimental investigation of two types of the vortex generator is presented. The qualitative and quantitative evaluations of the wake are made by flow visualization using smoke wire method and the measurement of vortex frequencies in the wind tunnel. From the experiment, following results were obtained that the delta wing type vortex generator is more effective than circular type because of the higher vortex frequencies and the smaller drag.

• Progress in Medical Physics
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• v.32 no.2
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• pp.25-39
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• 2021

Brachytherapy, along with external beam radiation therapy (EBRT), is an essential and effective radiation treatment process. In brachytherapy, in contrast to EBRT, the radiation source is radioisotopes. Because these isotopes can be positioned inside or near the tumor, it is possible to protect other organs around the tumor while delivering an extremely high-dose of treatment to the tumor. Brachytherapy has a long history of more than 100 years. In the early 1900s, the radioisotopes used for brachytherapy were only radium or radon isotopes extracted from nature. Over time, however, various radioisotopes have been artificially produced. As radioisotopes have high radioactivity and miniature size, the application of brachytherapy has expanded to high-dose-rate brachytherapy. Recently, advanced treatment techniques used in EBRT, such as image guidance and intensity modulation techniques, have been applied to brachytherapy. Three-dimensional images, such as ultrasound, computed tomography, magnetic resonance imaging, and positron emission tomography are used for accurate delineation of treatment targets and normal organs. Intensity-modulated brachytherapy is anticipated to be performed in the near future, and it is anticipated that the treatment outcomes of applicable cancers will be greatly improved by this treatment's excellent dose delivery characteristics.