• 제목/요약/키워드: Radiation effect

검색결과 3,580건 처리시간 0.037초

고방사선장내 작업 로봇용 이중 방사선 감지 시스템 (A Dual Radiation Monitoring System Ror Robot Working in High Radiation Field)

  • 이남호;조재완;김승호
    • 대한전기학회논문지:시스템및제어부문D
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    • 제54권9호
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    • pp.556-558
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    • 2005
  • The effect of high irradiation on inspection systems in a nuclear power plant can be severe, especially to electronic components such as control hoards. The effect may lead to a critical malfunction or trouble to a underwater robot for inspection and maintenance of nuclear reactor. However, if information on the total accumulated dose on the sensitive parts of the robot is available, a prediction of robot's behavior in radiation environments becomes possible. To know how much radiation the robot has encountered, a dosimeter to measure the total accumulated dose is necessary. This paper describes the development effort of a dual radiation monitoring system using a SiC diode as a dose-rate meter and a p-type power MOSFET as a dose meter. This attempt using two sensors which detect same radiation improves reliability and stability at high intensity radiation detection in nuclear facilities. It uses the concept of diversity and redundancy.

N-Acetylphytosphingosine Enhances the Radiosensitivity of Lung Cancer Cell Line NCI-H460

  • Han, Youngsoo;Kim, Kisung;Shim, Ji-Young;Park, Changsoe;Song, Jie-Young;Yun, Yeon-Sook
    • Molecules and Cells
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    • 제25권2호
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    • pp.224-230
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    • 2008
  • Ceramides are well-known second messengers that induce apoptosis in various kinds of cancer cells, and their effects are closely related to radiation sensitivity. Phytoceramides, the yeast counterparts of the mammalian ceramides, are also reported to induce apoptosis. We investigated the effect of a novel ceramide derivative, N-acetylphytosphingosine (NAPS), on the radiosensitivity of NCI-H460 human lung carcinoma cells and its differential cytotoxicity in tumor and normal cells. The combination of NAPS with radiation significantly increased clonogenic cell death and caspase-dependent apoptosis. The combined treatment greatly increased Bax expression and Bid cleavage, but not Bcl-2 expression. However, there was no effect on radiosensitivity and apoptosis in BEAS2B cells, which derive from normal human bronchial epithelium. Cell proliferation and DNA synthesis were significantly inhibited by NAPS in both NCI-H460 and BEAS2B cells, but only the BEAS2B cells recovered by 48h after removal of the NAPS. Furthermore, the NCI-H460 cells underwent more DNA fragmentation than the BEAS2B cells in response to NAPS. Our results indicate that NAPS may be a potential radiosensitizing agent with differential effects on tumor vs. normal cells.

Dynamics of charged particles around a compact star with strong radiation

  • 오재석;김홍수;이형목
    • 천문학회보
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    • 제36권1호
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    • pp.54.2-54.2
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    • 2011
  • It is the conventional wisdom that the Poynting-Robertson effect is essentially the outcome of the interplay between absorption and reemission processes. For a better understanding of the motion of charged particles around a compact star with strong radiation, we reached an alternative interpretation for the Poynting-Robertson effect based on the covariant formalism and found that it is attributed to the combination of the aberration and the Lorentz transformation of the radiation stress-energy tensor. As a general relativistic application of the Poynting-Robertson effect, we studied the dynamics of test particles around the spinning relativistic star with strong radiation. We discovered that the combination of the angular momentum and the finite size of the star generates "radiation counter drag" which exerts on the test particle to enhance its specific angular momentum, contrary to the radiation drag. The balance of the radiation drag and the radiation counter drag renders the particle to hover around the spinning luminous star at the "suspension orbit". The radial position and the angular velocity of the particle on the "suspension orbit" are determined by the angular momentum, the luminosity, and the size of the central star only, and they are independent of the initial position and velocity of the particle.

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Correction of Dose Distribution at Total Body Irradiation using Compensator

  • 김종식;조현상;김영곤;조정근;주상규;박영환
    • 대한방사선치료학회지
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    • 제9권1호
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    • pp.87-93
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    • 1997
  • The using of compensator is required to adjust the irregular dose distribution due to irregular thickness of the body in Total Body Irradiation. Aluminuim, copper or lead is generally used as compensator. In our study, we would like to introduce a result of the attenuation and compensation effect of radiation use compensator made by duralumin and its clinical use. The thickness of compensator was calculated by the attenustion of radiation, which was measured by polystyrene phantom and ionization chamber(farmer). The compensation effect of radiation was measured by diode detector. All of conditions were set as in real treatment, and the distanc from source to detector was 446 cm. We also made fixation of device to easily attach the compensator to LINAC. Beam spoiler was menufactured and placed on the patient to irradiate sufficient dose to the skin. diode detector were placed on head, neck, chest, umbilicus. pelvis and knee with each their entranced exit points, and datas of dose distribution were evaluated and compared in each points for eleven patients(Feb. 96-Feb. 97). The attenuation rate of irradiation by duralumin compensator was measured as $1.4\%$ in 2mm thickness. The mean attenuation rate was $1.3\%$ per 2mm as increasing the thickness gradually to 50 mm. By using duralunim compensator, dose distribution in each points of body was measured with ${\pm}2.8\%$ by diode detectior. We could easily calculate the thickness of compensator by measuring the attenuation rate of radiation, remarkably reduce the irragularity of dose distribution duo to the thickness of body and magnify the effect of radiation therapy.

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하계 그늘쉼터 유형별 장·단파복사 관측과 해석 (Observation and Analysis of Long and Short-wave Radiation According to Types of Summer Shelters)

  • 백창현;최동호;이부용;이인규
    • 한국태양에너지학회 논문집
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    • 제39권6호
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    • pp.127-135
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    • 2019
  • In this study, we analyzed the relationship between five factors: long-wave radiation, short-wave radiation, cloudiness, SVF and summer shelters. In the previous study, we recognized the correlation between single building SVF and long-wave radiation. Furthermore, this study attempted to confirm the relationship at the summer shelter with high solar radiation blocking rate. The observations are as follows. ① Cooling in summer shelters was not the effect of temperature but the effect of radiation reduction due to short-wave radiation shielding. ② In the case of the canopy tent with low heat capacity, the long-wave radiation was observed to be 16.7% higher per hour than the comparison control point due to the increase in surface temperature. ③ The long-wave radiation increase rate was different according to SVF, but showed very similar pattern according to the material characteristics of the summer shelters. ④ Passive Cooling effect on the type of summer shelters are determined by the size of the total long and short-wave radiation at that point.

인체 말초 혈액 림프구에서 저선량 방사선 조사에 의해 유도되는 적응 반응 (Adaptive Response Induced by Low Dose Ionizing Radiation in Human Lymphocytes)

  • 김정희;이경종;조철구;류성렬;김태환;김성호
    • Journal of Radiation Protection and Research
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    • 제20권2호
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    • pp.97-102
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    • 1995
  • 인체 말초 혈액 림프구에서 저선량의 감마선에 의해 유도되는 적응 반응을 관찰하였다. 인체 림프구를 저선량의 감마선(priming dose 0.01Gy) 을 조사한 후 여러 시간 간격 후 고선량 (challenging dose, 1.5Gy) 을 조사하였다. 저선량을 미리 조사한 림프구와 조사하지 않은 림프구에서 발생된 미세핵의 빈도를 계수하였다. 비세핵 발생 빈도는 저선량 조사 4시간 후 고선량을 조사하였을 때 최대 감소치를 보였다. 저선량과 고선량 조사 시간차가 7시간 또는 20시간이었을 때 미세핵 발생 빈도는 약간 감소하였으나 유의성은 없었다. 본 연구에서는 $G_0$상태의 세포주기에서 저선량을 조사하였을 경우 적응 반응이 나타나는 것이 관찰 되었다. 미세핵 분석법은 실험 방법이 비교적 간단하고, 기타 염색체 분석법에 비하여 빠른 시간내 결과를 도출 할 수 있어 추후 방사선에 대한 적응 반응의 연구에 유용한 지표가 될 수 있을 것이다.

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Radiation-induced Tumorigenesis

  • Kim, In-Gyu;Lee, Yun-Sil
    • BMB Reports
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    • 제36권1호
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    • pp.144-148
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    • 2003
  • During the past 2 decades, radiation tumorigenesis researchers have focused on cellular and molecular mechanisms. We reviewed some of these research fields, since they may specifically relate to the induction of cancer by ionizing radiation. First, radiation-mediated mutation was discussed. Then the initiating event in radiation carcinogenesis, as well as other genetic events that may by involved, is discussed in terms of the possible role of the activation of genes and the loss of cell-cycle checkpoints.

감마선 조사에 의한 수산 자숙액의 생리활성에 대한 연구 (Study on the Physiological Activities of Gamma-irradiated Seafood Cooking Drips)

  • 조으리;김연주;최종일;성낙윤;정필문;김재훈;송범석;윤요한;이주연;이주운
    • 방사선산업학회지
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    • 제4권1호
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    • pp.25-31
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    • 2010
  • Cooking drips which were obtained as by-product after seafood processing in the food industries, still contain lots of proteins, carbohydrates, and other functional materials. This study was conducted to investigate the effect of gamma irradiation on the biological activities of seafood cooking drips. When the cooking drips of Hizikia fusiformis, Enteroctopus dofleini and Thunnus thynnus were irradiated, the antioxidant activities, whitening effect, and angiotensin I converting enzyme inhibition activity of the ethanol extract from seafood cooking drips were all increased by gamma irradiation. This was because of the increased extraction efficiency of available compounds by irradiation. These results suggested that the seafood cooking drips, wasted as by-products, can be used as functional compounds with gamma irradiation treatment.