• Title/Summary/Keyword: Radiation effect

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Changes of Smoke Components and Smoke Odor by Far Infra-red Radiation in a Closed Room

  • Hwang, Keon-Joong;Rhee, Moon-Soo;Ra, Do-Young
    • Journal of the Korean Society of Tobacco Science
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    • v.20 no.2
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    • pp.198-204
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    • 1998
  • This study was conducted to evaluate the effect of far IR radiation for the elimination of sidestream smoke components in a closed room. The measurements covered particle sizes of 13.8-542.5 nm, particle concentration, TSP, UVPM, FPM, solanesol, and the following gases and vapor components of smoke: carbon dioxide, carbon monoxide, nicotine, and 3-ethenyl-pyridine. Also, the changes of smoke odor strength by far IR radiation were tested by using the electronic nose system. There was no difference between control and far IR radiation in changes of the concentration of $CO_2$ and CO. The concentrations of TSP, UVPM, FPM, solanesol, nicotine, and 3-ethenylpyridine were reduced by far IR radiation. The growth and diminishing rate of RSP diameter was accelerated by far IR radiation compared with control. There was a little difference of smoke odor change with far IR radiation by electronic nose system analysis. Our results indicated that the use of far IR radiation had a little effect on changes of solid, vapor, and odor of smoke, but it had no effect on gaseous components.

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Protective Effect of Silkworm Hemolymph against Gamma Irradiation Induced Damage in the Liver of Mice (방사선 손상 Balb/C 마우스 모델에서 누에 체액(Silkworm Hemolymph)의 간조직 보호 효과)

  • Nam, You Ree;Kang, Jung Ae;Rho, Jong Kook;Choi, Mi Hee;Utami, Hayu Tyas;Jang, Beom Su;Park, Sang Hyun
    • Journal of Radiation Industry
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    • v.8 no.1
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    • pp.7-10
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    • 2014
  • This study was designed to evaluate the protective effect of silkworm hemolymph against ${\gamma}-irradiation$ induced damage in the liver of mice. Female Balb/C mice (6 weeks old) were exposed to ${\gamma}-irradiation$ (6 Gy) and administered orally to silkworm hemolymph ($5ml\;kg^{-1}$ BW) for 7 days post-irradiation. The body weight, spleen index, plasma aspartate transaminase (AST), plasma alanine transaminase (ALT), and liver malondialdehyde (MDA) levels were determined. Compared with irradiated control mice, the activity of plasma AST and the level of MDA were significantly decreased in mice treated silkworm hemolymph. These results show that silkworm hemolymph is found to have a protective effect against ${\gamma}-irradiation$ induced damage in mice.

The protective effects of trace elements against side effects induced by ionizing radiation

  • Hosseinimehr, Seyed Jalal
    • Radiation Oncology Journal
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    • v.33 no.2
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    • pp.66-74
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    • 2015
  • Trace elements play crucial role in the maintenance of genome stability in the cells. Many endogenous defense enzymes are containing trace elements such as superoxide dismutase and metalloproteins. These enzymes are contributing in the detoxification of reactive oxidative species (ROS) induced by ionizing radiation in the cells. Zinc, copper, manganese, and selenium are main trace elements that have protective roles against radiation-induced DNA damages. Trace elements in the free salt forms have protective effect against cell toxicity induced by oxidative stress, metal-complex are more active in the attenuation of ROS particularly through superoxide dismutase mimetic activity. Manganese-complexes in protection of normal cell against radiation without any protective effect on cancer cells are more interesting compounds in this topic. The aim of this paper to review the role of trace elements in protection cells against genotoxicity and side effects induced by ionizing radiation.

Development of Electronic Portal Imaging Device and Treatment Position Verification for Fractionated Stereotatic Radiotherapy

  • Lee, Dong-Hoon;Ji, Young-Hoon;Lee, Dong-Han;Kim, Yoon-Jong;Chilgoo Byun;Hong, Seung-Hong;Rhee, Soo-Yong
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.446-449
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    • 2002
  • The video based electronic portal imaging device (EPID), which could display the portal image in near real time, was implemented to verify treatment position error in FSRT(Fractionated Stereotatic Radiation Therapy) instead of a portal film. Also, Developed FSRT system was composed of the stereotactic frame, frame mounting system and collimator cones. The verification of treatment position is very crucial in special therapies like FSRT. In general, the FSRT uses high dpse rate at small field size for treating small intracranial lesions. To evaluate quantitative positioning errors in FSRT, we used the first FSRT image as reference image and obtained the second FSRT image that was moved 2mm intentionally and detected intracranial contours after image processing. The generated 2mm error could be verified by overlapping only contours of two images. Through this study, the radiation treatment efficiency could be improved by performing precise radiation therapy with a developed video based EPID and FSRT.

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Indirect assessment of internal irradiation from tritium decay on Lemna Minor duckweed

  • Ifayefunmi, O.S.;Mirseabasov, O.A.;Synzynys, B.I.
    • Nuclear Engineering and Technology
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    • v.53 no.6
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    • pp.1991-1999
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    • 2021
  • The response changes of the specific growth rate of Lemna minor duckweed was modeled using the logarithms of frond numbers on tritium activity concentration and gamma radiation dose from cobalt 60. The concept of average specific growth rate depends on the general exponential growth pattern, where toxicity is estimated based on the effect on the growth rate. One of the main questions of the effect of the radiation dose on duckweed is how to correlate the effect of beta radiation with the effect of any other radiation for modeling radiation on Lemna minor. Experimental data were extrapolated by utilizing the OECD guidelines. A linear relationship of absorbed dose and activity concentration was obtained for the average dependency growth rate of Lemna minor as D = (0.1257)·A0.585. The dose rate of gamma irradiation from 60Co increases with tritium activity dependence, on the specific growth rate of the Lemna minor duckweed. An increase in the tritium activity causes a decrease in the specific growth rate of the Lemna minor duckweed. It indicates that as the quantity of the beta radiation dose increase in Lemna minor duckweed, a higher quantity of gamma radiation will be required to cause the same effect in the specific growth rate of Lemna minor duckweed. The relation between the inhibition of the Lemna minor seedling growth and gamma and beta radiation dosage agrees roughly with that between the decrease of survival rate or fertility and dosage.

Survey for the Side effects of Radiation Therapy Following Breast Cancer Surgery : Comparision of Modified Raidcal Mastectomy and Breast Conservative Surgery (유방암 환자의 수술후 방사선치료의 부작용의 변화 : 유방절제술과 유방보존술의 비교)

  • Chon, Myong-Hui
    • Journal of Haehwa Medicine
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    • v.5 no.2
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    • pp.473-484
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    • 1997
  • This study was performed to survey the specific information about the time of onset, frequency, duration, and severity of the side effect of radiation therapy following breast cancer surgery, and identify the difference of these data according to the type of breast cancer surgery : modified radical mastectomy(MRM) vs. breast consevative operation(BCO). 38 breast cancer patients were interviewed with side effect profile about radiation therapy. Interview was done weekley from the start of radiation therapy through 6 weeks and 3 month follow-up interview was done at 3 month after completion of the treatment. The results are as follow : 1. Total score of side effect experienced by the breast cancer patients was rapidly increased at 2-3 week after intiating treatement and continousely raised maintaing high score until completion of the treatement. Some problems like cough, dyspnea and pain were more experienced after treatment. 2. Patients with modified radical mastectomy showed more total score of side effects than patients with breast conservative operation. And both patients with MRM and BCO experienced similar pattern of side effect to radiation therapy. Through these data we concluded that side effect to radiation therapy was not ended at completion of treatement. Patents will continously experiend various problems and suffer from not only acute side effects like skin problem, sore throat and swollowing difficulty but also late effect of the radiation therapy. Clinically these data can be used for oncologic nurse to provide informational interventions to prepare breast cancer patients for the radiation therapy.

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Effects of the Radiation Benefits and Hazards on Overcoming Recognition of Fukushima Nuclear Disaster Using the Structural Equation Modeling (구조방정식모형을 이용한 방사선 이익성과 위험성이 후쿠시마 원전사고 극복 인식에 미치는 영향)

  • Seoung, Youl-Hun
    • Journal of radiological science and technology
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    • v.41 no.2
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    • pp.163-170
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    • 2018
  • The purpose of this study was to analyze the structural relationship between radiation hazards and radiation benefits effecting on overcoming recognition of Fukushima nuclear disaster (FND) in Japan by using structural equation modeling (SEM). The subjects were 248 undergraduates from one university in Chungbuk province in Korea. From June 1, 2017 to July 30, 2017, we conducted a questionnaire survey on the radiation hazards and radiation benefits and on the overcoming recognition of FND. As a result, it showed that the recognition of radiation hazards has a significant effect on the benefits of radiation, but does not directly affect the overcoming recognition of FND. However, the recognition of radiation benefits has been mediating between radiation hazards perception and the overcoming recognition of FND. Therefore, it can be empirically confirmed that despite the radiation hazards the recognition of overcoming the FND depends on the level of radiation benefits by using the SEM.

Effect of Demographic Factors, Radiation Knowledge Level, Radiation Awareness on Radiation Benefit by Hierarchical Regression Analysis Model (위계적 회귀분석 모형에 의한 인구학적 요인, 방사선 지식수준, 방사선 인식도가 방사선 이익성에 미치는 영향)

  • Myeong-Hoon Ji;Youl-Hun Seoung
    • Journal of radiological science and technology
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    • v.46 no.5
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    • pp.435-444
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    • 2023
  • The purpose of this study was to analyze the factors that demographic factors, radiation knowledge level, and radiation awareness could be affecting the benefits of radiation. From July 2022 to July 2023, after receiving consent to participate by using the link of Naver through Social Network Service (SNS) for the general public, 312 people were surveyed by self-registration method without collecting personal information. The questionnaire consisted of a total of 25 questions following demographic factors (5 questions including age group by life cycle, sex, monthly household income, residence), radiation knowledge level (8 questions including basic physical, biological effects, radiation protection technology), radiation awareness (12 questions including risk, management, benefit). Independent sample T-test and ANOVA tests were performed for significant differences in the average radiation awareness between variables, and hierarchical regression was performed to identify influencing factors on radiation benefits. As a result, the benefit of radiation was significantly high among the radiation awareness, but the awareness of the danger of radiation was insufficient to the level of recognizing it as safe. Men had significantly higher awareness of radiation management and benefits than women, and the awareness of radiation management was significantly higher in the middle class with a monthly household income of 4.31 million won or more. The higher the knowledge level of radiation, the higher the awareness of the benefits of radiation. The factors that had a positive effect on radiation benefits were the high level of radiation knowledge and awareness of radiation management.

INVOLVEMENT OF p27CIP/KIP IN HSP25 OR INDUCIBLE HSP70 MEDIATED ADAPTIVE RESPONSE BY LOW DOSE RADIATION

  • Seo, Hang-Rhan;Chung, Hee-Yong;Lee, Yoon-Jin;Baek, Min;Bae, Sang-Woo;Lee, Su-Jae;Lee, Yun-Sil
    • Nuclear Engineering and Technology
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    • v.38 no.3
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    • pp.285-292
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    • 2006
  • Thermoresistant (TR) clones of radiation-induced fibrosarcoma (RIF) cells have been reported to show an adaptive response to 1cGy of low dose radiation, and HSP25 and inducible HSP70 are involved in this process. In this study, to further elucidate the mechanism by which HSP25 and inducible HSP70 regulate the adaptive response, HSP25 or inducible HSP70 overexpressed RIF cells were irradiated with 1cGy and the cell cycle was analyzed. HSP25 or inducible HSP70 overexpressed cells together with TR cells showed increased G1 phase after 1cGy irradiation, while RIF cells did not. $[^3H]-Thymidine$ and BrdU incorporation also indicated that both HSP25 and inducible HSP70 are involved in G1 arrest after 1cGy irradiation. Molecular analysis revealed upregulation of p27Cip/Kip protein in HSP25 and inducible HSP70 overexpressed cells, and cotransfection of p27Cip/Kip antisense abolished the induction of the adaptive response and 1cGy-mediated G1 arrest. The above results indicate that induction of an adaptive response by HSP25 and inducible HSP70 is mediated by upregulation of p27Cip/Kip protein, resulting in low dose radiation-induced G1 arrest.

Effect of Gamma-Irradiation on the Cell Proliferating and Interleukin-2 Producing Activity of Mouse Splenocytes of Staphylococcal Enterotoxin B (감마선 조사가 Staphylococcal Enterotoxin B의 비장세포 증식률 및 Interleukin-2 분비능에 미치는 영향)

  • Park, Jong-Heum;Sung, Nak-Yun;Byun, Eui-Baek;Song, Du-Sup;Kim, Jae-Kyung;Song, Beom-Seok;Kim, Jae-Hun;Lee, Ju-Woon;Yoo, Young-Choon
    • Journal of Radiation Industry
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    • v.7 no.2_3
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    • pp.161-166
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    • 2013
  • The purpose of this study was to investigate the cell proliferating and interleukin-2 producing activity of staphylococcal enterotoxin B by gamma-irradiation. Staphylococcal enterotoxin B was gamma-irradiated with the various doses of 0, 2, 20 and 50 kGy. SDS-PAGE analysis showed that gamma-irradiation caused the sharp decrease of the content of staphylococcal enterotoxin B and the effect was irradiating dose-dependent. Non-irradiated staphylococcal enterotoxin B increased the cell proliferation of splenocytes isolated from female Balb/c mouse, whereas 2 kGy-irradiated toxin significantly decreased the activity. 20 and 50 kGy-irradiated staphylococcal enterotoxin B was no effect. A similar effect on the interleukin-2 production of mouse splenocytes was observed with non-irradiated and irradiated staphylococcal enterotoxin B. It was considered to be due to the decrease of the antigenicity of staphylococcal enterotoxin B by gamma-irradiation. Therefore, these results suggest that gamma-irradiation can be effective for the decrease of the antigenicity of staphylococcal enterotoxin B as superantigen.