• 제목/요약/키워드: Race factors

검색결과 151건 처리시간 0.025초

HPLC법을 이용한 HbA1c 측정시 Abnormal Peak의 빈도와 원인 (Factors Influencing Frequency of Abnormal Peak in the Measurement of HbA1c by HPLC)

  • 김선경;배애영;최대용;김명수;유광현;기창석
    • 대한임상검사과학회지
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    • 제37권2호
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    • pp.71-77
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    • 2005
  • We experienced the specimen that contains a hemoglobin variant known as interference from HbAS in October 2003. It was the first case of Hb variants since Samsung Medical Center began conducting glycohemoglobin College of American Pathologists surveys in 1997. The purpose of this study is to share our experience with the specimen and promote the understanding of Hb variants & derivatives. We've performed cross checks to examine HbA1c by using two pieces of equipment; the TOSHOH G7 and BIO-RAD VARIANT-T(turbo), and Automatic High Performance Liquid Chromatography(HPLC) as an analytic measurement method. HPLC provides different fractional information of hemoglobin with a two-dimensional graph as well as numeric results. We have been performing a "Systematic Checking Process". Three specimen suspicious of Hb variants & derivatives were found through this process. College of American Pathologists notified that it is important for users to be aware of the limitation of their glycohemoglobin method to avoid reporting incorrect results due to interference from hemoglobin variants or hemoglobin adducts. Therefore, laboratory findings of Hb variants & derivatives are very important. The experience of qualified technicians with professional knowledge in Hb variants is the most important aspect in finding Hb variants. Korea is homogeneous in race and is not in an area with a higher finding rate of Hb variants. While 1,024 cases of Hb variants have been found in Japan, we do not have specific data on how many cases of Hb variants have been found in Korea. Considering Hb variant cases in Japan, which is geographically close to us, it is presumed that there must be various Hb variant cases in Korea. If domestic laboratories set a systemic protocol and build a network to share our experience in Hb variants, I expect the Korean Hb variants could also be listed on the world's Hb variant list.

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국소적 치아이형성증 환아에 관한 증례 (REGIONAL ODONTODYSPLASIA : CASE REPORT)

  • 김지희;최병재;이제호;손흥규;김성오;최형준
    • 대한소아치과학회지
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    • 제36권1호
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    • pp.96-101
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    • 2009
  • 국소적 치아이형성증(regional odontodysplasia)은 매우 드물게 나타나는 치아의 형성 장애로서 치아 발육이 국소적으로 정지되어 발생하며 이환된 유치와 영구치의 모든 경조직이 발육 부전이나 석회화 부전을 나타내는 질환이다. 하악 보다는 상악에서 호발하는 것으로 알려져 있으며 인종간의 차이는 없고, 여성에서 2배 정도 많이 발생한다. 국소적 치아이형성증의 정확한 원인은 밝혀지지 않았으나, 국소적 혈액 순환 장애나 체성 돌연변이, 바이러스 침투, 치배 감염, 치아 외상, 이상고열, 방사선 조사, 영양 및 대사 장애, 유전 등이 보고되었다. 이환된 치아는 정상치아보다 크기가 작고, 저형성을 보이며, 노란색 또는 황갈색을 나타내고, 거칠고 취약한 치면을 가진다. 방사선학적인 특징은 법랑질이 정상의 경우보다 얇고 치밀하지 못하며, 상아질의 발육부전으로 치수강이 크고, 근관은 넓게 보이며, 치근은 짧고 불명확하게 보인다. 간혹 치관부가 너무 얇고 석회화가 불량하여 방사선사진에 보이지 않을 수도 있다. 이 증례는 연세대학교 치과대학병원 소아치과에 내원한 환아에 관한 증례로, 2세 3개월 남아에서 임상 구강검사 및 방사선사진검사 결과 하악 좌측 1/4 악의 유치열에 발육부전과 석회화부전 소견을 보이는 국소적 치아이형성증으로 진단되어 이를 보고하는 바이다.

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정상기능 갑상선 결절 환자에서 갑상선 유두암의 의미 있는 예측인자로서 혈청 갑상선 자극호르몬의 역할 (The Role of Serum Thyrotropin Level as a Meaningful Predictor of Papillary Thyroid Cancer in Patients with Nontoxic Nodular Goiter)

  • 문신제;박정환;이유화;홍상모;이창범;박용수;김동선;최웅환;안유헌
    • 대한두경부종양학회지
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    • 제27권2호
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    • pp.198-203
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    • 2011
  • Background and Objectives : Distinguishing benign from malignant lesion in thyroid noddex is important but clinically difficult. FNAB is the first investigation of choice. However, cytologic results are often indeterminable. In those cases, additional molecular biologic tests are helpful. If serologic tests are available to predict malignancy, it can be useful to fortify accurate diagnosis. We analyzed whether TSH or FreeT4 level could be used as a predictor of malignancy. Materials and Methods : From January 2008 to March 2009, 540 patients received one of thyroidectomy in a single center. We only included 167 patients from 18 to 65 years old without cardiopulmonary or renal disorders. All the patients were in euthyroid state and took no medications, which affect the thyroid function. We reviewed charts retrospectively to find out differences in TSH level and FreeT4 level between the benign and malignant groups. Results : In this study, all the patients with malignancy had the papillary cancer. In benign group, average TSH level came out to be 1.48mU/L, whereas the average TSH level of malignant group was 1.98 mU/L. Moreover, the higher the cancer stage was, the higher the TSH level was. Although we have adjusted factors that can affect TSH level(age, sex, race, goiter type), we still received the same result. The risk of malignant cancer increased in proportion with TSH level within the normal range. In free T4 level, there was no difference between benign and malignant group. Conclusion : We propose that TSH level can play a role as one of the predictors for thyroid cancer. However, there is limitation because all the patients with malignancy in this study have papillary cancer. Thus, we can apply this result only in papillary cancer, and we need more study for other types of thyroid cancer.

기초 및 광역지자체 기후변화 취약성 평가를 위한 웹기반 지원 도구(VESTAP) 개발 (Development of Web-Based Supporting Tool (VESTAP) for Climate Change Vulnerability Assesment in Lower and Municipal-Level Local Governments)

  • 오관영;이명진;한도은
    • 한국지리정보학회지
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    • 제19권1호
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    • pp.1-11
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    • 2016
  • 기후변화는 환경 분야에서 가장 주목받는 화두이며, 인류에게 직면한 가장 도적적인 과제이다. 이러한 문제를 해결하는 방법은 다양하지만, 우리나라의 경우 국가 차원의 1~2차 국가기후변화 적응대책을 수립하고, 각 광역 및 기초 지자체의 기후변화 적응 시행대책 수립을 의무화하고 있다. 기후변화 취약성 평가는 기후변화 적응 시행대책을 수립함에 있어 필수적인 역할을 담당한다. 그러나 취약성 평가는 다양한 영향인자의 복합적 연산을 통해 도출됨으로 개별적인 평가를 수행하기에는 어려움이 있다. 이에 본 연구에서는 기초 및 광역 지자체 차원에서 활용 가능한 웹기반 기후변화 취약성 평가 지원도구(VESTAP)를 개발하였다. VESTAP은 크게 지표 DB와 취약성 평가 및 표출 도구로 구성되어 있다. 지표 DB는 RCP(Representative Concentration Pathways) 4.5와 8.5로 모의된 총 455개의 미래 기후자료, 대기 환경자료, 기타 인문사회통계 자료와 그에 따른 메타데이터 정보를 포함한다. 표출 도구는 각 취약성 평가의 결과에 대한 공간분포, 편향성, 도표화 등 다양한 분석 기능을 제공함으로써 편의성을 극대화 하였다. VESTAP를 활용하여 세종특별자치시에 대한 미세먼지에 의한 건강 취약성 평가를 시범적으로 수행하였으며, 부강면이 상대적으로 취약성이 가장 높은 수치를 나타냈다. 개발된 도구를 활용하여 각 지자체는 보다 쉽고, 편리하게, 그리고 과학적 증거에 기반한 기후변화 적응 시행대책을 수립할 수 있을 것으로 기대한다.

Comparison of the Formula of PSA, Age, Prostate Volume and Race Versus PSA Density and the Detection of Primary Malignant Circulating Prostate Cells in Predicting a Positive Initial Prostate Biopsy in Chilean Men with Suspicion of Prostate Cancer

  • Murray, Nigel P;Reyes, Eduardo;Fuentealba, Cynthia;Orellana, Nelson;Morales, Francisca;Jacob, Omar
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권13호
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    • pp.5365-5370
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    • 2015
  • Background: Combining risk factors for prostate cancer into a predictive tool may improve the detection of prostate cancer while decreasing the number of benign biopsies. We compare one such tool, age multiplied by prostate volume divided by total serum PSA (PSA-AV) with PSA density and detection of primary malignant circulating prostate cells (CPCs) in a Chilean prostate cancer screening program. The objectives were not only to determine the predictive values of each, but to determine the number of clinically significant cancers that would have been detected or missed. Materials and Methods: A prospective study was conducted of all men undergoing 12 core ultrasound guided prostate biopsy for suspicion of cancer attending the Hospital DIPRECA and Hospital de Carabineros de Chile. Total serum PSA was registered, prostate volumecalculated at the moment of biopsy, and an 8ml blood simple taken immediately before the biopsy procedure. Mononuclear cells were obtained from the blood simple using differential gel centrifugation and CPCs identified using immunocytchemistry with anti-PSA and anti-P504S. Biopsy results were classed as positive or negative for cancer and if positive the Gleason score, number of positive cores and percent infiltration recorded. Results: A total of 664 men participated, of whom 234 (35.2%) had cancer detected. They were older, had higher mean PSA, PSA density and lower PSA-AV. Detection of CPCs had high predictive score, sensitivity, sensibility and positive and negative predictive values, PSA-AV was not significantly different from PSA density in this population. The use of CPC detection avoided more biopsies and missed fewer significant cancers.Conclusions: In this screening population the use of CPC detection predicted the presence of clinically significant prostate cancer better than the other parameters. The high negative predictive value would allow men CPC negative to avoid biopsy but remain in follow up. The formula PSA-AV did not add to the predictive performance using PSA density.

더러브렛 경주마의 주파기록에 대한 유전모수 추정과 연도별 개량량 분석 (Estimation of Genetic Parameters and Annual Trends for Racing Times of Thoroughbred Racehorses)

  • 오승윤;박종은;이정란;이진우;오희석;김희발
    • Journal of Animal Science and Technology
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    • 제51권2호
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    • pp.129-134
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    • 2009
  • 본 연구는 1990년부터 2008년까지 서울경마공원과 부산 경마공원에서 활동한 경주마 13,458두의 총 245,979개의 경주관측기록을 이용하여 국내 더러브렛 경주마의 유전능력과 연도별 개량량을 분석하였다. 모든 관측치들의 주파기록을 1400m 경주거리에 맞추어 보정하고, 기수와 조교사에 대해 평균수득상금의 순위에 따라 번호를 부여하였으며, 후보 설명변수들에 대해 AIC, BIC를 사용한 단계적 변수 선발법을 적용하였다. 19년간 국내에서 활동한 경주마들의 주파기록에 대한 유전력과 반복력은 각각 0.322, 0.332로 추정되었고, 연평균 표현형 개량량과 유전적 개량량은 -0.166초, -0.161초로 산출되었다. 경주마의 유전모수와 개량량의 추정 연구에 있어 무엇보다 설명력 높은 개체모형의 수립이 중요하다고 생각되며, 이는 실제 경주마의 능력을 효과적으로 반영하는 반응변수의 설정과 통계학적 기법을 활용한 체계적인 설명변수의 선발을 통해 가능하다

경극(京劇) $\ll$독목관(獨木關)$\gg$의 연개소문(淵蓋蘇文) 무대의상(舞台衣裳) 디자인 연구(硏究) - 무대의상(舞台衣裳)의 상징적(象徵的) 의미(意味)를 중심(中心)으로 - (A Study on Stage Costume of Yean-GaeSoMoon(Korean) in the Peking Opera <> - Focusing on Symbolic Meaning of Stage Costume -)

  • 신경섭;조규화
    • 패션비즈니스
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    • 제2권3호
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    • pp.121-136
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    • 1998
  • The purpose of this study was to present a new research method of stage costume by designing and making the stage costume of Yean-GaeSoMoon(淵蓋蘇文) in Peking Opera Du Mu Guan (Korean; Dog Mog Guan, 獨木關). The stage costume of Peking Opera was formed on the basis of the Chinese traditional stage costume in the Qing period, however the style of stage costume was beautified the costume of Ming period and here contained the factors of successive costumes. But the stage costume of Peking Opera didn't have the same rank system with real history costume and didn't have demarcation according to period and history. In the stage costume of Peking Opera, the color is cultural language that can inform spectators of sex, age, personality, position of characters. The pattern of decoration also symboled the personality and characteristic of the character. Yean-GaeSoMoon in the play wore green armour (Chinese; ru ying kao 綠硬靠), red pants (Chinese; hong ku 紅褲), red mustache (Chinese; hong ran kou 紅髥口), crown (Chinese; da e zi 大額子), shoes (Chinese; hou di xue 厚底靴) and Xue RenGui wore white armour (Chinese; baikao 白靠), red pants (Chinese; hong ku 紅褲), shoes (Chinese; hou di xue 厚底靴), hat (Chinese; za jin 扎巾). By historical materials, Yean-GaeSoMoon was a nationalist who uphold national sprit and the greatest hero of the age and a charismatic politician who combines literatural arts with military arts. Considering these reviews, defined the thema of his new costumes' image as "the flying bird which has three legs"(三足鳥), the bird which symbolized the sun and immortality in Koguryo fresco. On the basis of this image, presented three types of Yean-GaeSoMoon's stage costume. Yean-GaeSoMoon as the minister in the court wore black gown (Chinese; mang pao 蟒袍) of dargon pattern which symbolizes harisma who opening the heaven. He as the general who directs war wore red mantle (Chinese; dou peng 斗蓬) which symbolizes the blue dragon that soaring into the sky, as the officer who fights the enemy's general wore green armour (Chinese; gai liang jia 改良甲), red pants (Chinese; hong ku 紅褲) which symbolizes the flying Sward that blowing violently. By wearing these stage costumes, the image of Yean-GaeSoMoon could changed from the fierce general of minority race who likes to fight, to the Koguryo general who fights against enemy at the risk of his life for Koguryo's autonomy. Through this study once again we could realized that stage costume played very mportant part In outstnding the characteristic of actor in the Peking Opera.

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Associations Between Body Fat Percentage and Fitness among Police Officers: A Statewide Study

  • Violanti, John M.;Ma, Claudia C.;Fekedulegn, Desta;Andrew, Michael E.;Gu, Ja K.;Hartley, Tara A.;Charles, Luenda E.;Burchfiel, Cecil M.
    • Safety and Health at Work
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    • 제8권1호
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    • pp.36-41
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    • 2017
  • Background: Police work is generally sedentary although there may be situations that require physical endurance and strength, such as foot chases and arresting suspects. Factors such as excessive body fat can impede an officer's physical ability to deal with such occurrences. Our objective was to examine associations between officers' body fat percentage (BF%) and performance on a standardized fitness protocol. Methods: Data were obtained from fitness screening among 1,826 male and 115 female officers in a large US police agency. The screening consisted of a 2.4-km run, push-ups, sit-ups, and sit-and-reach test. Sex-specific body fat percentages were estimated from skinfold thickness measured using calipers. Linear regression models were used to examine unadjusted and adjusted mean scores of fitness tests across BF% tertiles. Results: The prevalence of overall fitness was 4.3 times greater in male officers and 3.6 times greater in female officers having the lowest BF% tertile compared with the highest tertile (30.3% vs 7.1% and 46.0% vs 12.8%, respectively). BF% was linearly and positively associated with the time of 2.4-km run (p < 0.001), and linearly and inversely associated with the number of push-ups (p < 0.001), sit-ups (p < 0.001), and the distance of sit-and-reach (p < 0.001) in men. Similar associations were observed in women with the exception of sit-and-reach (p = 0.122). Associations were independent of age, race/ethnicity, rank, and duty station. Conclusion: Overall, BF% was inversely associated with fitness levels in male and female officers. Future longitudinal studies should be initiated to explore the potentially causal relationship between BF% and fitness in law enforcement officers.

해양스포츠 이벤트 관람자의 이미지, 만족도가 재방문 및 추천의도에 미치는 영향: 2015부산컵 세계여자매치레이스 요트대회를 중심으로 (The Effect of Marine Sport Event Visitors' Satisfactions and City Image on Revisit and Recommendation: Focusing on 2015 Busan Cup Women's International Match Race)

  • 김찬룡;이재빈;장승현
    • 한국체육학회지인문사회과학편
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    • 제56권1호
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    • pp.53-65
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    • 2017
  • 본 연구는 2015 부산컵 세계여자매치레이스 관람자의 이미지, 만족도가 재방문 및 추천의도에 미치는 영향을 살펴보는데 그 목적이 있다. 이를 위해 관람자의 사회통계학적 특성을 분석하고 도시이미지, 만족도, 재방문 및 추천의도간의 영향관계를 살펴보았다. 그 결과 첫째, 요트대회 관람자의 동반자는 '가족 및 친척'이 가장 많았으며, 대회정보 획득 경로는 '기타' 즉, 현장에서 직접 알게 되었다는 응답이 가장 많았고, 교통수단은 '승용차'가 가장 많았다. 또한 관람목적은 '지역관광'이 가장 많았으며, 체류기간은 '당일'이 가장 많았다. 둘째, 요트대회 관람자의 이미지와 만족도는 재방문 및 추천의도에 유의한 영향을 미치는 것으로 나타났다. 구체적으로는 만족도의 하위요인인 프로그램만족도와 진행용원만족도가 재방문 및 추천의도에 유의한 정적영향을 미치고 있었다. 이러한 연구결과를 통해 본 대회의 미흡함(홍보부족, 연계성, 매력성 부족)을 확인할 수 있었고 지속가능한 대회로 거듭나기 위해서는 어떠한 부분들이 개선되어야할지를 알 수 있었다.

특정 대상에 대한 개인 수준의 문화적 성향이 사용자 경험에 미치는 조절효과에 대한 실증적 연구: 미국, 독일, 러시아의 4개 디지털 기기 사용자를 대상으로 (An Empirical Study on How the Moderating Effects of Individual Cultural Characteristics towards a Specific Target Affects User Experience: Based on the Survey Results of Four Types of Digital Device Users in the US, Germany, and Russia)

  • 이인성;최지웅;김소령;이기호;김진우
    • Asia pacific journal of information systems
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    • 제19권1호
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    • pp.113-145
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    • 2009
  • Recently, due to the globalization of the IT(Information Technology) market, devices and systems designed in one country are used in other countries as well. This phenomenon is becoming the key factor for increased interest on cross-cultural, or cross-national, research within the IT area. However, as the IT market is becoming bigger and more globalized, a great number of IT practitioners are having difficulty in designing and developing devices or systems which can provide optimal experience. This is because not only tangible factors such as language and a country's economic or industrial power affect the user experience of a certain device or system but also invisible and intangible factors as well. Among such invisible and intangible factors, the cultural characteristics of users from different countries may affect the user experience of certain devices or systems because cultural characteristics affect how they understand and interpret the devices or systems. In other words, when users evaluate the quality of overall user experience, the cultural characteristics of each user act as a perceptual lens that leads the user to focus on a certain elements of experience. Therefore, there is a need within the IT field to consider cultural characteristics when designing or developing certain devices or systems and plan a strategy for localization. In such an environment, existing IS studies identify the culture with the country, emphasize the importance of culture in a national level perspective, and hypothesize that users within the same country have same cultural characteristics. Under such assumptions, these studies focus on the moderating effects of cultural characteristics on a national level within a certain theoretical framework. This has already been suggested by cross-cultural studies conducted by scholars such as Hofstede(1980) in providing numerical research results and measurement items for cultural characteristics and using such results or items as they increase the efficiency of studies. However, such national level culture has its limitations in forecasting and explaining individual-level behaviors such as voluntary device or system usage. This is because individual cultural characteristics are the outcome of not only the national culture but also the culture of a race, company, local area, family, and other groups that are formulated through interaction within the group. Therefore, national or nationally dominant cultural characteristics may have its limitations in forecasting and explaining the cultural characteristics of an individual. Moreover, past studies in psychology suggest a possibility that there exist different cultural characteristics within a single individual depending on the subject being measured or its context. For example, in relation to individual vs. collective characteristics, which is one of the major cultural characteristics, an individual may show collectivistic characteristics when he or she is with family or friends but show individualistic characteristics in his or her workplace. Therefore, this study acknowledged such limitations of past studies and conducted a research within the framework of 'theoretically integrated model of user satisfaction and emotional attachment', which was developed through a former study, on how the effects of different experience elements on emotional attachment or user satisfaction are differentiated depending on the individual cultural characteristics related to a system or device usage. In order to do this, this study hypothesized the moderating effects of four cultural dimensions (uncertainty avoidance, individualism vs, collectivism, masculinity vs. femininity, and power distance) as suggested by Hofstede(1980) within the theoretically integrated model of emotional attachment and user satisfaction. Statistical tests were then implemented on these moderating effects through conducting surveys with users of four digital devices (mobile phone, MP3 player, LCD TV, and refrigerator) in three countries (US, Germany, and Russia). In order to explain and forecast the behavior of personal device or system users, individual cultural characteristics must be measured, and depending on the target device or system, measurements must be measured independently. Through this suggestion, this study hopes to provide new and useful perspectives for future IS research.