• 제목/요약/키워드: Race Factors

검색결과 150건 처리시간 0.025초

Correlation of Hormone Receptor and HER-2/neu Expression with Clinicopathologic Parameters in Primary Breast Tumors

  • Shaikh, Fouzia;Jamal, Qamar;Baig, Saeeda;Hadi, Naila Irum;Majeed, Noman
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권7호
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    • pp.3363-3367
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    • 2016
  • Background: Breast cancer (BC) is a major health issue worldwide as well as in Pakistan. All women belonging to any race, ethnicity or lineage are in danger of developing breast cancer. Significant factors influencing the development of breast malignancies are the genetic background, environmental conditions, reproductive parameters, the consequences of female hormones both intrinsic and extrinsic, alteration of immune status, and biologic determinants. Materials and Methods: Overall 150 biopsy proven patients were included in the study. Samples were submitted for histopathology and determination of estrogen and progesterone receptor expression and HER-2/neu status. Associations with other characteristics like age, tumor stage, node involvement, histological grade were also studied. Results: Mean age at presentation was 46.7 years. The majority had invasive ductal carcinoma, 100 (84.7%), and were in stage pT3, 54 (45.7%). Important relationships (P<0.05) were found among ER, PR positivity, and Her 2 neu overexpression. However, no noteworthy link was identified amongst ER, PR, Her 2 neu and tumor grade, stage, age, lymph node involvement except for the menopausal status. Conclusions: In summary, breast cancer patients featured an advanced stage of disease, more lymph node involvement, and moderately high grade tumors and with more estrogen, progesterone receptor and HER-2 positive tumors.

리투아니아 민속복식의 고찰 (A Study on Lithuanian Folkcostume from 19th Century)

  • 김문영;조우현
    • 복식
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    • 제52권7호
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    • pp.27-44
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    • 2002
  • The Folk-dress of some parts of the traditional style is extremely focused and puts value on protecting itself against changes. Generally rural areas are much more conservative politically economically, and culturally. Its environment is sluggish and slow and daily routines change slowly. So they take friendly a position between a race and geographical and environmental differences which is expressed in the Folk-dress. Also, a dress is the most preferred individual object as a symbol of collective homogeneity. By those people who preserve these kinds of the individual objects and by those people who have ethnic conservation, folk-dress was handed down to the present age and the festival dress was used as a tool of ethnic tradition and binding. Therefore, 1 would like to study and research the differences between the folk-dress of the Lithuanian historical and geographical factors and the folk-dress of the surrounding north-eastern European countries. Especially when we compare these with the folk-dress in terms of historical, cultural. and political relationships between Lithuania and the north-eastern European countries, we can find out that they had a good effect on the folk-dress historically and culturally.

CaWRKY2, a Chili Pepper Transcription Factor, Is Rapidly Induced by Incompatible Plant Pathogens

  • Oh, Sang-Keun;Yi, So Young;Yu, Seung Hun;Moon, Jae Sun;Park, Jeong Mee;Choi, Doil
    • Molecules and Cells
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    • 제22권1호
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    • pp.58-64
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    • 2006
  • WRKY family proteins are a class of plant-specific transcription factors involved in stress response signaling pathways. In this study a gene encoding a putative WRKY protein was isolated from a pepper EST database (http://genepool.kribb.re.kr). The cDNA, named Capsicum annuum WRKY2 (CaWRKY2), encodes a putative polypeptide of 548 amino acids, containing two WRKY domains with zinc finger motifs and two potential nuclear localization signals. Northern blot analyses showed that CaWRKY2 mRNA was preferentially induced during incompatible interactions of pepper plants with PMMoV, Pseudomonas syringae pv. syringae 61, and Xanthomonas axonopodis pv. vesicatoria race 3. Furthermore, CaWRKY2 transcripts were strongly induced by wounding and ethephon treatment, whereas only moderate expression was detected following treatment with salicylic acid and jasmonic acid. CaWRKY2 was translocated to the nucleus when a CaWRKY2-smGFP fusion construct was expressed in onion epidermal cells. CaWRKY2 also had transcriptional activation activity in yeast. Taken together our data suggest that CaWRKY2 is a pathogen-inducible transcription factor that may have a role in early defense responses to biotic and abiotic stresses.

정상인과 녹내장 환자의 혈청 인지질 지방산 농도 (Fatty Acid Concentration of Serum Phospholipids in Normal and Glaucoma Patients)

  • 정혜연
    • 한국식생활문화학회지
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    • 제35권2호
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    • pp.224-232
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    • 2020
  • Glaucoma is one of the leading causes of blindness worldwide and is characterized by degeneration of the optic nerve. Elevated intraocular pressure (IOP) is the major contributing factor to optic nerve damage. However, some patients develop glaucoma even with normal IOP. Other factors, including age, race, myopia, and nutrition, can affect glaucoma risk. Dietary fat intake and serum fatty acid composition are closely related with the fatty acid profile of the retina and thus can modulate glaucoma risk. In this study, we collected serum samples from 34 glaucoma patients (26 primary open angle glaucoma (POAG) and 8 normal tension glaucoma (NTG)) and 45 healthy controls and analyzed their serum phospholipid fatty acid concentrations. The results show that the ratio of oleic acid to stearic acid (OA/SA), which is an indicator of stearoyl-CoA desaturase activity, was higher in POAG patients when compared to normal controls. The ratio of eicosapentaenoic acid to arachidonic acid (EPA/AA), which is an indirect marker of eicosanoid biosynthesis, was also higher in glaucoma patients (p=0.048). These results imply that dietary fatty acid intake and serum fatty acid profile can influence glaucoma risk. Additional study is necessary to identify the relationship between fatty acids and glaucoma.

Impact of Foreign Direct Investment on Power Sector: An Empirical Study with Refrence to India

  • Maran, K.;Anitha, R.
    • 동아시아경상학회지
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    • 제3권1호
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    • pp.8-16
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    • 2015
  • In the later quarter of the twentieth century, the need for foreign capital is realized among the various countries of the world. Developing countries especially developed multi-pronged strategies to attract foreign capital into the country. One such strategy is the adoption of liberalization policy. Almost all the developing countries started opening their economy, out of the compulsion, to achieve faster rate of economic growth and development. Even a communist country like China adopted liberalization policy as a strategy for accelerated economic growth during 1979. India also joined the race by 1991, when the government announced the policy of liberalization. The importance of FDI extends beyond the financial capital that flows into the country. The huge size of the market in this sector and high returns on investment are two important factors in boosting FDI inflows to power sector. 100 percent FDI is allowed under automatic route in almost all the sub sectors of power sector except the atomic energy. Major foreign investment is made in this sector during 2000 to 2009 is Mauritius with an investment of US$ 4490.96 i.e., 4.24 percent of the total FDI inflows into the country during the period. The estimation of future FDI flow shows a marginal decline in the year 2010. Then from 2011 to 2015 onwards upward trend of FDI was observed.

Prospects of Application of Linkage Disequilibrium Mapping for Crop Improvement in Wild Silkworm (Antheraea mylitta Drury)

  • Vijayan, Kunjupillai;Singh, Ravindra Nath;Saratchandra, Beera
    • International Journal of Industrial Entomology and Biomaterials
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    • 제20권2호
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    • pp.37-43
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    • 2010
  • The wild silkworm, Antheraea mylitta Drury (Lepidoptera: Saturniidae) is a polyphagous silk producing insect that feeds on Terminalia arjuna, T. tomentosa and Shorea robusta and is distributed in the forest belts in different states of India. Phenotypically distinct populations of the A. mylitta are called "eco-race" or "ecotypes". Genetic improvement of this wild silkworm has not progressed much due to lack of adequate information on the factors that control the expression of most of the economically important traits. Considering the amazing technological advances taking place in molecular biology, it is envisaged that it is now possible to take greater control on these intractable traits if a combination of genetic, molecular and bioinformatics tools are used. Linkage disequilibrium (LD) mapping is one such approach that has extensively been used in both animal and plant system to identify quantitative trait loci (QTLs) for a number of economically important traits. LD mapping has a number of advantages over conventional biparental linkage mapping. Therefore, LD mapping is considered more efficient for gene discovery to meet the challenge of connecting sequence diversity with heritable phenotypic differences. However, care must be taken to avoid detection of spurious associations which may occur due to population structure and variety interrelationships. In this review, we discuss how LD mapping is suitable for the dissection of complex traits in wild silkworms (Antheraea mylitta).

A Profile of Non-Seekers of Health Information Among the United States Foreign-Born Population

  • Kim, Soojung;Huang, Hong;Yoon, JungWon
    • Journal of Information Science Theory and Practice
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    • 제8권1호
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    • pp.68-78
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    • 2020
  • This study attempted to uncover the characteristics of health information non-seekers among the United States foreign-born population and identify potential predictors of their non-seeking behavior. The trends of foreign-born health information nonseekers over the past twelve years were also examined. Statistical analysis was conducted with two sets of Health Information National Trends Survey (HINTS) data: HINTS 2 (2005) and HINTS 5 Cycle 1 (2017) datasets. It was found that foreign-born nonseekers differ from foreign-born seekers in terms of a variety of variables including education, income, English proficiency, the uses of Internet and social media, ownership of digital devices, ownership of health insurance, perceived health status, and level of trust in health information sources. Among them, education, Internet use, and trust in online health information were identified as predictors of the foreign-born population's non-seeking of health information. In addition, three variables - race/ethnicity, age, and place of accessing the Internet - which were significant factors in the 2005 dataset, were no longer significant in the 2017 dataset, implying the possible influence of smartphones that reduces Internet accessibility gaps among different racial/ethnic and age groups.

TPS Analysis, Performance Indicator of Public Blockchain Scalability

  • Hyug-Jun Ko;Seong-Soo Han
    • Journal of Information Processing Systems
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    • 제20권1호
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    • pp.85-92
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    • 2024
  • In recent years, Bitcoin and Ethereum have witnessed a surge in trading activity, driven by venture capital investment and funding through initial coin offerings (ICOs) and initial exchange offerings (IEOs). This heightened interest has led to kickstarting a vibrant ecosystem for blockchain development. The total number of cryptocurrencies listed on CoinMarketCap.com has reached 2,274 highlights how dynamic and wide blockchain development landscape has grown. In blockchain development, new blockchain projects are being created by forking blockchains inspired by major cryptocurrencies such as Bitcoin and Ethereum. These projects aim to address the perceived shortcomings and improve existing technologies. Altcoins, representing these alternative cryptocurrencies, are an ongoing industry effort to improve performance and security with enhancement proposals such as Bitcoin Improvement Proposals (BIP), Ethereum Improvement Proposals (EIP), and EOSIO Enhancement Proposals (EEP). With competitive attempts to improve blockchain performance and security, an ongoing performance race between various blockchains has taken shape, each claiming its own performance advantages. In this paper, we describe the transactions contained in the blocks of each representative blockchain, and find the factors that affect the transactions per second (TPS) through transaction processing and block generation processes, and suggest their relationship with scalability.

성인 남성의 혈청 테스토스테론 농도와 전립선 특이항원의 관계에 대한 통합적 고찰 (The Relationship Between Levels of Serum Testosterone and Prostate-specific Antigen in Healthy Men: An Integrative Review)

  • 안경주
    • Journal of Korean Biological Nursing Science
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    • 제22권2호
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    • pp.71-80
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    • 2020
  • Purpose: The purpose of this study was to review primary research exploring the correlations between the levels of serum testosterone and the prostate-specific antigen (PSA) in healthy men without prostate diseases. Methods: An integrative review was conducted using the Whittemore & Knafle (2005) framework. The keywords, 'testosterone & prostate-specific antigen', 'testosterone & PSA' and 'healthy men' were used to search peer-reviewed publications in six databases. Among 1,959 searched articles, eleven articles were selected after excluding articles that do not meet inclusion criteria. Literature quality was moderate (Level 3). Results: As a result of this study, it was confirmed through the nine articles that healthy adult men showed no significant correlation between the serum testosterone and the PSA. Conversely, two articles presented that the serum PSA correlate positively with the testosterone. In particular, it is inferred that the effect of the serum testosterone and the PSA secreted into a 24-hour circadian rhythm with different amplitudes and slopes would have had great influence. However, it does not consider the factors affecting the testosterone and the PSA, such as race, liver disease, and BMI, so there is insufficient empirical data to clearly explain the relationship between the testosterone and the PSA. Conclusion: The correlation between the serum testosterone and the PSA in healthy adult men is insignificant in relation to the circadian rhythm of the testosterone and the PSA secretion. It is that a large-scale study including various influencing factors using new biochemical indicators such as pro PSA be conducted in the future.

부산시 거주공간분화의 시대사적 함의 (Historical Implications of Residential Segregation in Busan, Korea)

  • 배미애
    • 한국지역지리학회지
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    • 제13권5호
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    • pp.477-494
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    • 2007
  • 본 논문은 부산시를 대상으로 1900년대 초(구한말)부터 현재에 이르기까지 거주지역의 불평등한 현상을 거주분화의 개념을 중심으로 사회공간적으로 분석한다. 부산은 1900년대 초 조선 전통사회의 성격을 이어받아 신분사회의 계층질서에 의한 거주선택의 제한으로 불평등한 거주공간이 형성되었다. 이후 일제에 의한 신시가지의 형성으로 기존의 한국인 거주지와 분리되는 현상을 경험하였으며 일본인과 한국인, 그리고 중국인 거주지역으로 구분되는 민족별 분화 현상도 나타났다. 해방과 한국전쟁 이후 급속하게 인구가 증가함으로써 새로운 빈민거주지역이 등장하였고 이는 이후에 전개될 거주지 분화의 주요 요인으로 작용하게 된다. 빈민지역의 문제를 해소하기 위해 1960년대부터 실시한 정책이주는 제도상의 결점으로 인하여 큰 효과를 보지 못하였다. 1990년 이후 주민의 사회경제적 지위는 주택선택에 영향을 주어 주택계층에 의한 거주지역분화를 가능하게 하였다. 중간주택계층보다는 상 하위 주택계층이 거주공간의 불평등한 분포에 큰 영향을 주었다. 맥락적이고 시계열적인 접근방법을 시도하여 거주공간의 사회공간적 불평등에 관한 인과성을 파악하려고 시도한 본 연구는 미래에 전개될 거주공간패턴을 예측하고 다른 도시들의 거주공간연구에 도움을 줄 것으로 예상된다.

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