• The Plant Pathology Journal
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• 제29권4호
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• pp.364-373
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• 2013

It has been known that most regulation of pathogenicity factor (rpf ) genes in xanthomonads regulates virulence in response to the diffusible signal factor, DSF. Although many rpf genes have been functionally characterized, the function of rpfE is still unknown. We cloned the rpfE gene from a Xanthomonas oryzae pv. oryzae (Xoo) Korean race KACC10859 and generated mutant strains to elucidate the role of RpfE with respect to the rpf system. Through experiments using the rpfE-deficient mutant strain, we found that mutation in rpfE gene in Xoo reduced virulence, swarm motility, and production of virulence factors such as cellulase and extracellular polysaccharide. Disease progress by the rpfE-deficient mutant strain was significantly slowed compared to disease progress by the wild type and the number of the rpfE-deficient mutant strain was lower than that of the wild type in the early phase of infection in the inoculated rice leaf. The rpfE mutant strain was unable to utilize sucrose or xylose as carbon sources efficiently in culture. The mutation in rpfE, however, did not affect DSF synthesis. Our results suggest that the rpfE gene regulates the virulence of Xoo under different nutrient conditions without change of DSF production.

• Asian Pacific Journal of Cancer Prevention
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• 제14권10호
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• pp.6085-6088
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• 2013

Prostate specidic antigen (PSA) and digital rectal examination (DRE) are the known predictive factors for positive prostate biopsies differing according to the age, region and race. There have been only very limited studies about the impact of PSA on histological findings at prostate biopsy in Turkey. The aim of this study was to evaluate the impact of PSA and clinical stage on histologic findings of prostate biopsy in men older than 75 years of age as a first study in the Turkish population. A total of 1,645 consecutive prostate biopsies were included, with 194 men aged 75 or older. Cancer was identified in 104 patients (53.6%). Of the 104 positive biopsies, Gleason scores were less than 7 in 53 (49%) patients, 7 or greater in 51 (51%) patients. Positive prostate biopsies were significantly correlated with advanced age (p=0.0001), abnormal DRE (p=0.0001) and raised PSA (p=0.0001). The prostate volume was significantly correlated with advanced age especially in prostate cancer patients over 75 years, compared with those under 75 (p=0.0001). These results are useful for counseling men older than 75 years for prostate cancer detection. However, PCa screening decisions are currently based on urologist judgment and detection of latent asymptomatic disease is an important concern regarding costs, overdiagnosis, overtreatment and quality of life (QOL) for men aged 75 years and older. Healthy old patients with a long life expectancy need to be carefully evaluated for eligibility for PCa screening.

• Clinical and Experimental Pediatrics
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• 제63권2호
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• pp.48-51
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• 2020

Background: The etiopathogenesis of late preterm (LPT) birth is undetermined. Placental histopathology, which reflects an adverse intrauterine environment and is reportedly associated with preterm labor and neonatal morbidities, has not been studied in LPT infants. Purpose: We investigated placental pathological lesion as markers of an adverse intrauterine environment during LPT labor. Methods: This retrospective case-control study compared placental histopathological and clinical variables between LPT and term neonates. Placental variables included chorioamnionitis, funisitis, hemorrhage, abruption, infarction, calcification, and syncytial knots. Maternal variables included age, substance abuse, pregnancyassociated diabetes mellitus and hypertension, duration of rupture of membrane, antibiotic use, and magnesium sulfate, whereas, those of neonates included gestational age, birth weight, race, sex, and Apgar scores. Standard statistical proedures were applied to analyze the data. Results: Chorioamnionitis (50% vs. 17.8%, P<0.001) and funisitis (20% vs. 4.4%, P=0.002) were more common in term infants. Placental infarction rate was insignificantly higher in LPT infants (25.6% vs. 14.3%, P=0.08). The mothers in the LPT group were older (30.4 years vs. 28.1 years, P=0.05; odds ratio [OR], 1.06; 95% confidence interval [CI], 0.998-1.12, P=0.056) and more often suffered from hypertension (28.9 vs. 12.9 %, P=0.02), and received magnesium sulfate (48.9 vs. 20%, P< 0.001; OR, 2.86; 95% CI, 1.12-7.29, P<0.05). Duration of rupture of membrane was higher in term infants (13.6 hours vs. 9.1 hours, P<0.001). Chorioamnionitis (OR, 0.33; 95% CI, 0.13-0.79; P<0.05) was associated with a lower risk of LPT delivery. Conclusion: Placental infection is not a risk factor for LPT births. There is a nonsignificant predominance of vascular anomalies in LPT placentas. Higher maternal age, magnesium sulfate therapy, and maternal hypertension are clinical risk factors for LPT labor.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제28권6호
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• pp.440-455
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• 2002

The final goal for an orthognathic surgery is a functional and esthetic achievement based on occlusion theory. All the dental treatment should be done with the occlusion in mind, though, they tend to be ignored with no good reason. We cannot think of occlusion without temporomandibular joint because it is the first clue to define an occlusion. As normal occlusion comes from the central tendency of distribution of population, we can get it by examining the population that closely meet the criteria of ideal occlusion. To perform proper occlusal function and to maintain the stability after treatment, the case must be finished in normal occlusion closer to ideal one. Our aim is to achieve the ideal occlusal scheme like the mutually protected occlusion with the best masticatory efficiency and the stability. The facial esthetics are influened by culture, race and the time in which human live. While the occlusal function rarely changes as time goes by, esthetics tend to do from one country to another. Orthodontists and maxillofacial surgeons should have solid sets of treatment goals to achieve the best facial esthetics and the ideal occlusion dictated by the joint. Doing orthognathic surgery, two factors aforementioned should be taken into account to establish the Surgical Treatment Objectives(STO). The doctors who are planning orthognathic surgery need to have a very logical and systematic thought process to make STO. The author examined 28 selected beautiful Korean female adults with normal skeleton with normal occlusion and analyzed the hard and the soft tissue relationship into five parts : dentomaxillary relationship, intermaxillary relationship, posture to hard tissue relationship, facial balance, and posture to soft tissue relationship. This study presents a sequential flow of diagnosis and treatment planning especially for surgical patients and it also can be applied to the nonsurgical patients.

• 가족자원경영과 정책
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• 제8권2호
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• pp.61-84
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• 2004

This thesis attempted to generate ideal tea culture space that connects environment and culture. Therefore, this examines: First, history of tea and the characteristics of tea culture space from Gochosun to modern times was reviewed Second, psychological factors (spirit of tea) of Korea tea culture space were reviewed. Third, the connection between the concept of tea culture space and Human Ecosystem Model by was analyzed. Also, this thesis examined how the culture of ecosystem and why tea culture space is needed. because tea includes varieties of ingredients for protecting environmental pollution. Finally, tea culture spaces were reviewed each region during Chosun dynasty, and tea culture space of recent tea users. In order to study tea culture space, complex residential area and single residential areas were compared. The useful of tea culture space as a ecological space was also examined. To achieve the purpose of this study, related literatures were reviewed, and investigations of museums and a survey on modern living space were also conducted. The results show that the space of our tea culture were affected by nature worshipping of Gochosun, Buddhism of Koryo, and Confusianism of Chosun with 'Pungryu', the idea that enjoys nature, thereby applying environment-friendly ecological beauty to their living space and life. The cultyral space in Korea is composed of natural environment such as mountain, sea, rock, or trees and artificial environment such as pond or pavilion. In the future, oriental culture with metaphysical value will lead the world culture, and especially, tea culture would play an important role regardless of nationality, race, religion, and ideology. Therefore, establishing a tea culture space in a living space would be the fundamental methods that would be able to settle down such tea life into our daily life. Our attempts to create ecological tea culture space as a integrated cultural space of natural, artificial, and human behavioral environment will contribute to enhance our quality of life.

• Journal of the Korean Data and Information Science Society
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• 제23권4호
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• pp.627-641
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• 2012

본 연구는 다차원 분할표 형태로 정리된 범주형 자료가 결측치나 무응답을 가지고 있을 때 주어진 자료를 가장 잘 설명하고 예측의 정확도를 높일 수 있는 모형의 추정과 모형의 선택 문제를 다루었다. 무시할 수 없는 무응답 (non-ignorable non-response)체계하에서 최대우도 추정에서 발생할 수 있는 변방값 문제를 해결하기 위하여 계층적 베이지안 모형을 고려하였다. 또한 모형 적도를 높이기 위한 변수 조합을 찾는 모형 선택의 문제를 함께 다루었다. 베이지안 접근하에서 모형 선택의 문제를 다루기 위하여 베이즈 인자 (Bayes factor)를 모형 선택의 기준으로 이용하였다. 제시된 방법은 2004년 실시된 우리나라 국회의원 선거를 앞두고 수행된 여론조사 데이터를 이용하여 실증분석을 수행하였다. 분석결과 무시할 수 없는 무응답 체계하에서 설명변수로 투표참여여부를 이용하는 것이 가장 적합한 모형으로 판명되었다.

• Journal of Preventive Medicine and Public Health
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• 제39권1호
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• pp.81-86
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• 2006

Background: A number of studies have reported associations between the ambient air pollution concentrations and various health outcomes. Especially, ozone is well known for primary risk factor of asthma attacks. The results of a recent study indicate that the size of the effect on health outcomes due to air pollution varied according to several conditions, including age, gender, race and the socioeconomic status. Therefore, this study was conducted to examine the associations of ozone with the childhood asthma hospitalizations as stratified by the socioeconomic status (SES) at the community level in Seoul, Korea, 2002. Methods: SES at aggregated levels was measured on the basis of average regional health-insurance rate per citizen in the area. We applied the generalized additive model to analyze the effect of ozone on asthma after controlling for the potential confounding variables that were capable of influencing the results. Results: Our analysis showed that the number of children who were hospitalized for asthma increased as the SES of the residence area decreased. The estimated relative risks of hospitalization for asthma, as stratified by the SES of the community level, were 1.12 (95% confidence interval 1.00-1.25) in districts with the highest SES levels, 1.24 (95% CI=1.08-1.43) within the moderate SES levels, and 1.32 (95% CI=1.11-1.58) in the districts with the lowest SES levels. Conclusions: Our analysis showed that exposure to air pollution did not equally affect the health status of individuals. This suggests that not only the biological-sensitivity markers, but also the SES of the subjects should be considered as potentially confounding factors.

• Neurospine
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• 제15권4호
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• pp.383-387
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• 2018

Objective: Lower back pain (LBP) is a worldwide health problem, and magnetic resonance imaging (MRI) is a common modality used to aid in its diagnosis. Although specific guidelines for assessing the necessity of MRI usage exist, the use of MRI as the initial imaging method for LBP seems to be more common than necessary in general practice. Methods: We conducted a retrospective chart review of 313 patients who had undergone MRI of the lumbosacral spine during 2014-2015. We recorded and compared various factors, including age, sex, body mass index, current smoking status, race, symptoms, MRI findings, and progression to surgery within the next year. All rates were compared according to whether the MRI results showed radiographically significant findings (MRI-positive) or not (MRI-negative) using the chi-square or Fisher exact tests (if the expected cell count was <5). All analyses were performed using SAS version 9.4. Results: There were no statistically significant differences in the rates of each symptom between the MRI-positive and MRI-negative groups, which accounted for 58.5% (183 of 313) and 41.5% (130 of 313) of the MRIs, respectively. The difference in the rate of surgery in the next year (18% among MRI-positive patients and 8.5% among MRI-negative patients) was found to be statistically significant (p<0.05). Conclusion: Based on our findings, 41.5% of patients underwent lumbar MRI unnecessarily and 81% of patients with positive MRIs did not have surgery within the next year. Further physician training is needed to avoid unnecessary investigations and expenditures.

• 한국의류산업학회지
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• 제21권3호
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• pp.288-299
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• 2019

This study examined trends in model perceptions in the Asian fashion industry through a survey on the current status of using models, model attributes, and image recognition for companies and brands participating in the Seoul Fashion Week and Hong Kong Fashion Week. The results of the study are as follows. First, an examination of the races of models used for public relations by clothing and accessory companies indicated that the use of Asian and black models was lower than white models. Second, intimacy, reliability, similarity, and professionalism were derived as attributes for a public relation model. Among these factors, only 'intimacy' showed a difference between the countries. Third, Seoul Fashion Week participants gave the highest marks for the strong individuality of the models used for their brands; however, participants in the Hong Kong Fashion Week most appreciated suitability with products and professional appearance. Fourth, the different trends of model image recognition were shown through various analysis results by country or race, in which Seoul Fashion Week participants highly perceived the global and luxurious image of white models, and were generally highly satisfied with the models. In terms of the Hong Kong Fashion Week, Asian models tended to be perceived as a more casual image, and the participants held contributions to brand recognition as the most significant factor when using Asian models.

• 디지털융복합연구
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• 제19권2호
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• pp.403-408
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• 2021

RPG 게임에서 게임 플레이어에게 리얼리티를 준다는 측면에서 게임캐릭터의 개성 표현은 디자인 행위의 핵심의 하나라고 할 수 있다. 독특한 캐릭터의 개성이 플레이어의 관심과 몰입감을 높여 다양한 체험을 할 수 있도록 한다. 이론적 연구와 사례 분석을 통해 RPG게임 캐릭터 디자인에서의 개성 있는 표현 방식을 분석해봤다. RPG 게임에서 캐릭터의 개성을 표현하는 방식은 우선 게임의 시공간적 배경과 줄거리, 미션에 따라 캐릭터의 대략적인 성별, 인종, 직업, 기능 등 기본적인 정보를 제시한다. 그리고 캐릭터의 응용과 활용에 맞춰 구체적이고 풍성하게 캐릭터를 성장시키면서 체형, 움직임, 색채, 의상, 무기류 등을 더욱 정교하게 그려낸다. 이 연구는 감성적 디자인 이론의 관점에서 RPG게임 캐릭터의 개성 설계에 영향을 미치는 주요 요소를 획득하는 데 목적이 있다. 이에 의해 감성적인 디자인의 RPG게임 캐릭터 개성 디자인 방법을 제안한다.