• 박물관보존과학
• /
• 제14권
• /
• pp.29-35
• /
• 2013

백자투각연당초문지통과 같이 기형 및 장식기법이 복잡한 도자기의 경우, 기존에 사용되고 있는 복원제는 경화시간이 짧아 정교한 성형이 어려워 틀을 이용하여 복원한다. 하지만 틀을 이용한 복원 또한 시간적, 재료적인 단점이 있기 때문에 직접 복원하는 방법을 연구하고자 하였다. 복원제의 경화시간과 물성은 작업성과 밀접한 관계가 있기 때문에 복잡한 형태의 복원부를 직접 성형할 때는 충분한 가사시간이 확보되는 복원제가 필요하다. 소성점토(Original Sculpey)와 에폭시퍼티(Repair it Quik)를 각기 다른 비율로 혼합하여 가사시간, 색도 변화, 작업성에 대한 실험을 하였다. 실험결과 OS8 : RQ2의 비율로 혼합하였을 경우 가사시간이 충분하고 성형성이 좋았으며 황변도가 낮고 채색성이 좋아 가장 효과적이라는 것을 알 수 있었다.

• 한국환경농학회지
• /
• 제42권3호
• /
• pp.193-202
• /
• 2023

Residue monitoring of propiconazole (PCZ) in cabbage, shallot, and spinach was conducted under multi-trial greenhouse conditions. This study aimed to understand the fate of the applied fungicide in these vegetables. Furthermore, the associated health risk of PCZ in leafy vegetables was assessed through dietary risk assessment. Commercially available PCZ (22% suspension concentrate) was administered thrice according to the OECD fungicide application interval guideline. The plant samples were extracted using a slightly modified QuEChERS technique and analyzed using gas chromatography-tandem mass spectrometry. The average PCZ recovery was between 84.5% and 117.6%, with a <5% coefficient of variance. The dissipation of PCZ residue in cabbage, shallot, and spinach after 14 days was 96%, 90%, and 99%, respectively, with half-lives of <5 days. Meanwhile, dietary risk assessments of PCZ residues in the studied vegetables using the risk quotient (RQ) were significant < 100 (RQ < 100). Thus, the population groups considered in this study were not at substantial risk from consuming leafy vegetables sprayed with PCZ following critical, good agricultural practices.

• 생약학회지
• /
• 제54권1호
• /
• pp.27-37
• /
• 2023

This research was conducted to investigate the comprehensive effects of methanol extract of Coptidis rhizoma (MECR) against oral pathogen. We studied the antibacterial, anti-biofilm, anti-gingipain and anti-inflammatory activity of MECR. The minimum bactericidal concentration (MBC) of MECR was 100 ㎍/mL against several oral pathogens. The formation of biofilm of Streptococcus mutans was reduced to 8.93~24.12% in the presence of 25 ㎍/mL of MECR. The gingipain activity of Porphyromonas gingivalis were reduced to 3.91~6.23% in case of Kgp and 5.73~7.78% in case of Rgp in the presence of 10 mg/mL of MECR. The expression of fadA mRNA, virulence factor of Fusobacterium nucleatum (F. nucleatum) was 3 folds decreased in the presence of 25 ㎍/mL of MECR. In case of YD-38 cells challenged with F. nucleatum, RQ values of IL-8 and IL-6 were reduced about 12 folds and 5.45 folds in the presence of 2 ㎍/mL of MECR. In case of RAW 264.7 murine cell challenged with F. nucleatum, RQ values of IL-1β and IL-6 were 2.52 folds and 2.55 folds reduced in the presences of 2 ㎍/mL of MECR. Conclusively, MECR showed potent antibacterial and anti-inflammatory effects against oral pathogenic bacteria.

• Asian Pacific Journal of Cancer Prevention
• /
• 제17권4호
• /
• pp.2159-2164
• /
• 2016

Background: A diagnosis of chronic myeloid leukemia (CML) is made on discovery of the presence of a Philadelphia (Ph) chromosome. The success of the treatment of this form of leukemia with tyrosine kinase inhibitor (TKI) is monitored by reduction of the Ph chromosome. Objective: To compare the role of conventional cytogenetic (CC) methods with a real time quantitative polymerase chain reaction (RQ-PCR) and fluorescence in situ hybridization (FISH) for diagnosis and treatment monitoring of CML patients. The secondary outcome was to analyze the treatment responses to TKI in CML patients. Materials and Methods: This was a retrospective study of CML patients who attended the Hematology clinic at Chiang Mai University Hospital from 2005-2010. Medical records were reviewed for demographic data, risk score, treatment response and the results of CC methods, FISH and RQ-PCR. Results: One hundred and twenty three cases were included in the study, 57.7% of whom were male with a mean age of 46.9 years. Most of the patients registered as intermediate to high risk on the Sokal score. At diagnosis, 121 patients were tested using the CC method and 118 (95.9%) were identified as positive. Five patients failed to be diagnosed by CC methods but were positive for BCR-ABL1 using the FISH method. Imatinib was the first-line treatment used in 120 patients (97.6%). In most patients (108 out of 122, 88.5%), a complete cytogenetic response (CCyR) was achieved after TKI therapy and in 86 patients (70.5%) CCyR was achieved long term by the CC method. Five out of the 35 analyzed patients in which CCyR was achieved by the CC method had a positive FISH result. Out of the 76 patients in which CCyR was achieved, RQ-PCR classified patients to only CCyR in 17 patients (22.4%) with a deeper major molecular response (MMR) in 4 patients (5.3%) and complete molecular response (CMR) in 55 patients (72.4%). In the case of initial therapy, CCyR was achieved in 95 patients (79.1%) who received imatinib and in both patients who received dasatinib (100%). For the second line treatment, nilotinib were used in 30 patients and in 19 of them (63.3%) CCyR was achieved. In half of the 6 patients (50%) who received dasatinib as second line or third line treatment CCyR was also achieved. Conclusions: CML patients had a good response to TKI treatment. FISH could be useful for diagnosis in cases where CC analysis failed to detect the Ph chromosome. RQ-PCR was helpful in detecting any residual disease and determining the depth of the treatment response at levels greater than the CC methods.

• 한국산업경영시스템학회:학술대회논문집
• /
• 한국산업경영시스템학회 2002년도 춘계학술대회
• /
• pp.69-78
• /
• 2002

This paper examines the effects on mental fatigue of changes in the intensity of physical activity. A treadmill-equipped instrument and perception tester were used to attain several levels of physical activity In this paper, In order to determine the individual levels of physical activity of subjects, Borg-RPE scale, Heart Rate(HR) and Respiratory Quotient(RQ) were used. Also, an addition test in whole-body activity on treadmill-equipped instrument as an indicator of mental fatigue were performed. In the above experiments, the scores obtained in addition test administered before and after physical activity at each intensity level used. Restricted within the limits of this paper, the results of these tests showed that mental fatigue decreased after physical activity.

• 한국IT서비스학회지
• /
• 제13권2호
• /
• pp.71-82
• /
• 2014

Exhibitions are important sales promotional method commonly used by the marketer of industrial products. Exhibition utilized as a means of effective marketing tools, company's interest and demand is rising. Especially in recent years, visitors' activity within the exhibition space can be monitored in real time by applying near-field sensing technology such as RFID, NFC, RQ code. Exhibition organizers are also applying the near-field sensing technology in order to attract the participating companies and visitors. With the introduction of near-field sensing technology, the exhibition has been a lot of changes occur in the exhibition environment. However absence of performance indicators to measure new exhibition environment which adopt ubiquitous technology, still the exhibition performance is not properly measured. In this study, we use the Delphi technique with the performance indicators based on previous research, and propose performance indicators for measuring achievement of exhibition in the smart-exhibition environment.

• 제어로봇시스템학회:학술대회논문집
• /
• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
• /
• pp.174-174
• /
• 2000

Q-learning, based on discrete state and action space, is a most widely used reinforcement Learning. However, this requires a lot of memory and much time for learning all actions of each state when it is applied to a real mobile robot navigation using continuous state and action space Region-based Q-learning is a reinforcement learning method that estimates action values of real state by using triangular-type action distribution model and relationship with its neighboring state which was defined and learned before. This paper proposes a new Region-based Q-learning which uses a reward assigned only when the agent reached the target, and get out of the Local optimal path with adjustment of random action rate. If this is applied to mobile robot navigation, less memory can be used and robot can move smoothly, and optimal solution can be learned fast. To show the validity of our method, computer simulations are illusrated.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2011년도 제40회 동계학술대회 초록집
• /
• pp.357-358
• /
• 2011

Dichloro-(2,2)-paracyclophane을 출발 물질로 하여 화학기상증착법(CVD)을 이용해 우수한 투명성과 수분 투과성을 갖는 poly(p-xylylene) 코팅 막을 얻었다. 상기 코팅 막을 얻기 위한 최적의 공정 조건은 Deposition Pressure 0.02~0.04Torr, Vaporization temperature $110{\sim}150^{\circ}C$으로 확인 되었다. 이러한 공정 조건으로 500 mm*500 mm size의 PET bare film을 코팅 기재로 사용하여 $10{\mu}m$, $20{\mu}m$의 parylene 코팅 막을 얻었고 이를 특성 분석해 보았다. 상기 코팅 막은 전체적으로 ${\pm}1{\mu}m$의 thickness uniformity가 관찰 되었고 투과율은 90% 이상을 보였으며 수분 투과율은 기재 대비 상대적으로 40%의 향상이 기대 되었다. 또한 우수한 내식성, 내염기성, 내용제성을 갖고 있었으며 PET 기재에 대해 우수한 부착력을 가지고 있었다. surface morphology는 AFM을 통해 분석하였으며 Ra가 15.123, Rq가 22.859로 측정 되었다.

• 제어로봇시스템학회지
• /
• 제20권4호
• /
• pp.37-43
• /
• 2014

소형 무인항공기가 발달함에 따라 영상센서의 활용이 증가하였다. 특히 발전된 컴퓨팅 파워와 소형화된 영상센서의 발달로 무겁고 값비싼 레이더 장비의 기술을 영상센서로 구현하는 연구가 활발히 진행 중이다. 영상 이동표적표시(Moving Target Indication MTI) 기법은 이런 시대의 흐름에 따라 발달된 기술이며 현재 미군의 소형무인항공기 RQ-11 Raven에 상용화 되었다. 본 논문에서는 소형 무인항공기용 영상 MTI 기법의 원리를 설명하고 영상 MTI에서 주로 사용하는 카메라 운동 보 정 기법인 매개변수/비매개변수 방식의 영상정합의 접근법을 위주로 설명하였다. 또한 소형 무인항공기용 영상감시시스템 구현에서 가장 큰 문제점인 시차/항공기 진동 보정에 대한 진행 중인 연구논문도 소개하였다.

• 한국항공운항학회지
• /
• 제31권1호
• /
• pp.1-10
• /
• 2023

This study investigated the accident cases of the U.S. Air Force and the R.O.K. Army. It analyzed the accident factors of the unmanned aircraft system using case analysis on unmanned aircraft system operators of the R.O.K. Air Force. Following the analysis this paper suggested safety operation plans for the R.O.K. Air Force. The risk factors of unmanned aircraft system were summarized by collecting and analyzing accident cases of unmanned aircraft system by the U.S. Air Force, collecting and analyzing accident risk factors of RQ-4 operators of the R.O.K. Air Force. Through the analyzed risk factors, a safety operation plan for the semi-automatic unmanned aircraft system and the fully automatic unmanned aircraft system was presented.