• 한국정보통신학회논문지
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• 제17권8호
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• pp.1899-1907
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• 2013

본 논문에서는 초미세 패턴으로 구성된 칩-온-필름(Chip-on-Film, COF) 패키징 작업에서 발생하는 결함들을 참조영상에 기초하여 효율적으로 검출하고 분류하는 시스템을 제안한다. COF패키징 제작 과정에서 발생하는 치명적인 결함은 개방(open), 일부개방(mouse bite, near open), 단락(hard short) 및 돌기(protrusion, near short, soft short) 등을 포함한다. 이러한 결함을 검출하기 위해서는 기존에 직접 육안으로 식별하거나 또는 전기회로 설계를 이용하는 방법을 사용하였다. 그러나 이러한 방법은 매우 많은 시간과 고비용이 요구되는 단점이 있다. 본 논문에서는 참조영상을 사용하여 효과적으로 결함유무를 판단하고 결함이 발생되는 경우에 결함의 종류를 4 가지 형태로 분류하는 시스템을 제안한다. 제안방식은 검사영상의 전처리, 관심영역 추출, 지역이진분석에 의한 이물 특징 분석과 분류 등을 포함한다. 수많은 실험을 통해, 제안된 시스템은 초미세 패턴을 가진 COF의 결함 검사 및 분류에 대해 기존의 방식에 비해 시간과 경비를 줄이는데 효과적임을 보인다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2018년도 춘계학술대회
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• pp.510-512
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• 2018

제안 논문은 초음파 진단에서 발생되는 영상에서 잡음을 제거하기 위해 웨이블릿 변화를 이용한 노이즈 제거를 통해 영상의 해상도를 높여준다. 초음파 영상의 주된 화질저하 요인인 speckle 잡음의 감소와 에지의 강화를 위한 알고리즘을 제안하였다. 제안된 알고리즘은 주파수와 공간 정보를 모두 사용할 수 있는 웨이블릿 변환을 이용하여, 다양한 크기의 에지를 강화할 수 있다. 초음파 영상이 노이즈 제거를 위한 알고리즘의 수행 속도는 $520{\times}440$ 영상에 대해 약 0.45ms로 빠르게 수행됨을 실험을 통해 확인하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.97-102
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• 2013

Objective: The aim of this study was to develop an automated computer-aided diagnostic system for diagnosis of thyroid cancer pattern in fine needle aspiration cytology (FNAC) microscopic images with high degree of sensitivity and specificity using statistical texture features and a Support Vector Machine classifier (SVM). Materials and Methods: A training set of 40 benign and 40 malignant FNAC images and a testing set of 10 benign and 20 malignant FNAC images were used to perform the diagnosis of thyroid cancer. Initially, segmentation of region of interest (ROI) was performed by region-based morphology segmentation. The developed diagnostic system utilized statistical texture features derived from the segmented images using a Gabor filter bank at various wavelengths and angles. Finally, the SVM was used as a machine learning algorithm to identify benign and malignant states of thyroid nodules. Results: The SVMachieved a diagnostic accuracy of 96.7% with sensitivity and specificity of 95% and 100%, respectively, at a wavelength of 4 and an angle of 45. Conclusion: The results show that the diagnosis of thyroid cancer in FNAC images can be effectively performed using statistical texture information derived with Gabor filters in association with an SVM.

• Applied Microscopy
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• 제44권4호
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• pp.138-143
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• 2014

Transmission electron microscope (TEM) is an excellent tool for studying the structure and properties of nanostructured materials. As the development of $C_s$-corrected TEM, the direct analysis of atomic structures of nanostructured materials can be performed in the high-resolution transmission electron microscopy (HRTEM). Especially, fast Fourier transform (FFT) technique in image processing is very useful way to determine the crystal structure of HRTEM images in reciprocal space. To apply FFT technique in HRTEM analysis in more reasonable and friendly manner, we made a new circular region of interest (C-ROI) FFT script and tested it for several HRTEM analysis. Consequentially, it was proved that the new FFT application shows more quantitative and clearer results than conventional FFT script by removing the streaky artifacts in FFT pattern images. Finally, it is expected that the new FFT script gives great advantages for quantitative interpretation of HRTEM images of many nanostructured materials.

• 전자공학회논문지SC
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• 제48권6호
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• pp.57-62
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• 2011

본 논문에서는 초전도 자석의 자장 균일도를 개선하기 위한 방법으로 3가지 형태의 magnet 모델을 제안하고 각각의 자석 형태에 대하여 같은 세기의 자장을 (Magnet field strength) 가질 경우에 최소전력 방식으로 최적화된 전류 분포에 해당하는 coil wire의 길이, 그리고 해당 조건에서의 자장의 불균일도를 시뮬레이션을 통하여 비교, 분석하였다. 구성된 3가지 magnet type을 동일한 조건 (계산 점의 개수 18개, 20cm DSV)에 대해서 wire길이와 main field inhomogeneity를 비교하였으며, 이러한 시뮬레이션 결과를 통하여 얻을 수 있는 결론은 계산점의 수가 적을수록 wire의 길이는 짧아지나 field inhomogeneity는 높아진다는 것이다. 즉, Magnet shim을 수행할 경우 계산점을 줄이는 방법으로는 짧은 wire의 길이와 main field homogeneity를 동시에 만족하도록 최적화 하는 것이 거의 불가능함을 의미하는 것이다. 그러나 DSV를 줄였을 경우에 계산점을 줄였을 때에 비해 우수한 결과 값을 얻을 수 있었다. 결론적으로 공간적으로 개방되어 있는 magnet model의 경우 계산점을 줄여 shimming을 진행할 경우 동일한 imaging region의 크기에 대해 더 많은 전류(또는 wire 길이)가 필요하고 field 균일도도 떨어졌으나 작은 ROI를 대상으로 영상을 얻는 경우 유용하게 사용될 수 있다.

• 대한핵의학회지
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• 제25권1호
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• pp.6-16
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• 1991

Regional cerebral blood flow (rCBF) was evaluated in 12 children ranging in age from 2.7 to 10.0 yr using $^{99m}Tc-HMPAO$ SPECT. For quantitative analysis, 13 pairs of homologous regions of interest (ROIs) were created on three attenuation-corrected 18.8 mm thick transverse slices matching the cerebral cortical regions, deep gray matter, cerebellar hemisphere, and vascular territories, and the semiquantitative indices including "right to left ratio" [(mean count/voxel of homologous right ROI) / (mean count/voxel of homologous left ROI)] and "regional index"(RI) [(mean count/voxel of a ROI)/ (mean count/voxel of all ROIs of each hemisphere)] were calculated. Mean values of right to left ratios of homologous regions ranged from 0.984 to 1.028 in children under 5 yr (group 1) and from 0.982 to 1.012 in children between 5 and 10 yr (group 2), and the mean $value{\pm}2S.D.$ for each region did not exceed 11% and 12% in group 1 and group 2, respectively. There were no statistically significant differences between the RIs of the homologous right and left regions. Significant differences of RIs were found both between vascular regions (p<0.0005 for goup 1, and p=0.0001 for goup 2) and between regions of cerebral cortices (p<0.0005 for group 1, and p<0.005 for group 2) with a relatively high value in the occipital cortex and the lower values in the cerebellum and deep gray matter among the regions of cerebral cortices in both groups. There were no significant differences between the RIs of corresponding regions of group 1 and group 2, except a significantly higher value of right deep gray matter in group 2 than in group 1(p=0.0301). The RIs of the superior frontal cortex and deep gray matter showed to be positively correlated with age (superior frontal cortex; right: rs=0.5254, p=0.0814, left : rs=0.5919, p=0.0496/deep gray matter; right: rs=0.8246, p=0.0062, left: rs=0.6266, p=0.0377). The results suggest that the rCBF pattern of children approaches that of adults in an accipito-rostral direction. This time course of rCBF changes is in agreement with behavioral, neurophysiological, and anatomical alterations known to occur in the developing brain.

• 사상체질의학회지
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• 제14권1호
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• pp.26-33
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• 2002

1. Purpose The purpose of this article was to find the change of Dong-mu's conceptions about constitutional disease through comparing with ${\ulcorner}$Sasang-Yihak-chobonguen${\lrcorner}$, ${\ulcorner}$Dongyi Soose Bowon${\lrcorner}$ written in 1894(Old edition) and ${\ulcorner}$Dongyi Soose Bowon${\lrcorner}$ published in 1901(In Edition) 2. Methods Comparing with ${\ulcorner}$Sasang-Yihak-chobonguen${\lrcorner}$, ${\ulcorner}$Dongyi Soose Bowon${\lrcorner}$ written in 1894(Old edition) and ${\ulcorner}$Dongyi Soose Bowon${\lrcorner}$ published in 1901(In Edition) we found the change of Dong-mu's conceptio ns about constitutional disease 3. Result 1) In ${\ulcorner}$Sasang-Yihak-chobonguen${\lrcorner}$, diseases were classified 'Oi-Gam(外感)‘, ’Nae-sang(內傷)‘, ’Ok-roi(牢獄)‘. ’Wi-gyoung(危傾)‘. In ${\ulcorner}$Sasang-Yihak-chobonguen${\lrcorner}$ ordinary symptoms was more impotant than disease, and good life style was emplasized for health 2) In ${\ulcorner}$Dongyi Soose Bowon${\lrcorner}$ written in 1894(Old edition), diseases were classified 'Oi-Gam(外感)‘, ’Nae-sang(內傷)‘. siseases from exterior causes was classified into 'Oi-gam-noi-chu-byoung(外傷腦?頁病)’, and diseases from interior causes was classified into 'Nae-sang-wi-wan-byoung(內觸胃脘病).‘ Herbal medication yet was't used by Disease 3) In ${\ulcorner}$Dongyi Soose Bowon${\lrcorner}$ published in 1901(In Edition), diseases was classified not by causes of disease but by mechanism and symptom of disease, so into Exterior-cold disease' and 'Interior-hot disease'. Herbal medication was used by pattern of Disease. 4) Conception of constitutional diseases was gradualy complished through edition.

• 한국멀티미디어학회논문지
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• 제16권7호
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• pp.870-878
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• 2013

본 논문에서는 생체인증 시스템의 하나인 지문인식 시스템의 정확도와 효율성을 높이기 위한 새로운 지문 분류 방법을 제안한다. 기존 연구에 따르면 지문은 융선과 골의 방향과 형상에 따라 몇 가지 유형으로 분류할 수 있다. 지문 데이터베이스를 사전에 유형에 따라 분류해 놓고 인식 대상인 지문의 유형을 정확하게 분류할 수 있다면 지문 인식 시간을 크게 줄일 수 있다. 왜냐하면 선택된 부류 안의 지문들만을 상대로 인증 대상인 지문과 비교하면 되기 때문이다. 본 논문은 우선 지문 영상으로부터 실제 지문 정보가 위치하는 관심영역 추출 방법을 제시한다. 다음엔 추출된 관심영역을 대상으로 질감 인식기반의 명암도 동시발생 행렬과 웨이브릿 변환을 통한 특징 추출 방법을 제시하고 기존의 명암도 동시발생 행렬만을 이용한 특징 추출 방법과 다층 퍼셉트론 및 서포트 벡터 머신을 사용해 성능을 비교한다.

• 핵의학기술
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• 제19권1호
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• pp.67-71
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• 2015

Purpose At recently, we enter into the aging society and a age-related disease is increasing. Among that, prevalence of degenerative brain disease like Parkin's disease will be increased. So, many radiopharmaceuticals is developed to diagnosis early and to evaluate the performance of therapeutic drugs. Especially $^{18}F-DOPA$ which involved at dopamine synthesis and function of storage is widely used to the diagnosis of Parkinson's disease as well as brain tumors. in the study, we will evaluate the distribution pattern of $^{18}F-DOPA$ at the striatum by using dynamic study. Materials and Methods We used Biograph Truepoint(Siemens, Germany) as PET/CT scanner, injected a $^{18}F-DOPA$ ($600{\pm}30MBq$) to patient (4men, 6women. $67{\pm}11age$) who visited our hospital from June to September, started 95min dynamic study at same time. after finishing acquisition, we reconstructed PET data with 19 frame every 5 minutes, analysed a average counts at ROI's where set at both striatums, anterior putamen, posterior putamen Results Counts in the cerebellum as the background formed a plateau after 90 minutes from the highest out rapidly reduced to 15 minutes. Counts of anterior putamen and posterior gradually increased but formed a plateau after 60min. A count ratio of Striatum to cerebellum was continuously increased up to more than 95 minutes, A count ratios of an anterior putamen to posterior one formed a plateau after 85 minutes. Conclusion The dynamic acquisition can be possible to evaluate a distribution of the $^{18}F-DOPA$ in the striatum and the VOI analysis through a dynamic acquisition and a variety of patterns. Futhermore, to make a uniformed distribution and count ratio of striatum to cerebellum, a static acquisition will have to start 90minutes later after injection.

• 대한정형도수물리치료학회지
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• 제27권1호
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• pp.21-30
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• 2021

Background: This study aimed to investigate the effects of muscle energy technique (MET) and instrument assisted soft tissue mobilization (IASTM) on knee extension ROM, knee extensor/flexor strength and muscle thickness immediately and after 24 hours. Methods: A total of 30 subjects participated in this study. The participants were assigned to either MET (n=15) or IASTM (n=15). 90-90 straight leg raise, knee extensor/flexor muscle strength, muscle thickness test were measured before, immediately after and 24 hours after the intervention. Results: Both groups significantly improved knee extension ROM on immediate (MET 10.7°, IASTM 10.21° increased) and after 24 hours assessment (MET 5.61°, IASTM 5.47° increased)(p<.05). In the MET group, knee extension and flexion muscle strength increased immediately after intervention (p<.05). In the IASTM group, knee extension muscle strength increased and knee flexor muscle strength decreased immediately after intervention (p<.05). Furthermore, both groups showed a pattern of returning to the initial strength after 24 hours. In both groups, no significant difference in muscle thickness immediately and after 24 hours was observed (p>.05). Conclusion: According to the results of the present study, MET and IASTM technique showed lasting effectiveness in flexibility of shortened hamstring immediately after and in 24 hours after the intervention. In both groups, MET increased muscle strength and increased ROM, while IASTM decreased muscle strength and increased ROM, with no change in muscle thickness.