• 음성과학
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• 제15권3호
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• pp.67-78
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• 2008

This study was intended to analyze how well people with right hemisphere damage can understand Korean proverbs. This study used a between-subject design and within-subjects design where all subjects participate in the three experiments for 10 hospitalized patients of whose average age is 66.1 years old and 10 normal adults in the same age range. Experiment 1 was to make up Korean proverb related stories and suggest it in written, Experiment II was to suggest a picture presenting a Korean proverb and the proverb itself directly, and Experiment III was to make up a story related to a Korean proverb and tell it auditory. Five Korea proverbs were used for each experiment; 15 in total. The results were as follows: First, there was a significant difference in understanding of Korean proverbs between normal adults and people with right hemisphere damage. Second, there was no significant difference of understanding between them by stimulating methods to suggest Korean proverbs. Third, people with right hemisphere damage had a tendency to interpret Korean proverbs literally as a total wrong reaction was composed of 55.36%. Considering the above the results, it can be said that people with right hemisphere damage have less understanding of Korean proverbs than normal adults, which is not affected by a way of or a condition of suggesting Korean proverbs in people with RHD, and they are inclined to make literal interpretation of Korean proverbs as they are.

• 천문학회보
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• 제43권1호
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• pp.57.1-57.1
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• 2018

Reionisation in the early Universe is likely driven by dwarf galaxies. Using cosmological RHD simulations, we study star formation and the escape of Lyman continuum (LyC) photons from mini-haloes with Mhalo<108Msun. We find that feedback reduces star formation very efficiently in mini-haloes, resulting in the stellar mass consistent with the empirical stellar mass-to-halo mass relation derived in the local Universe. Because star formation is stochastic and dominated by a few gas clumps, the escape fraction in mini-haloes is generally determined by photo-ionization, rather than supernova explosions. We find that the photon number-weighted mean escape fraction in mini-haloes is higher (20-40%) than that in atomic-cooling haloes. Despite their high escape fractions, LyC photons from mini-haloes are of minor importance for reionization due to inefficient star formation. We confirm previous claims that stars in atomic-cooling haloes with masses $10^8M_{sun}$$10^{11}M_{sun}$ are likely to be the most important source of reionization.

• 자동차안전학회지
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• 제7권1호
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• pp.27-32
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• 2015

In order to protect occupant during car crash accident, Regulation and NCAP(New Car assessment Program) have been developed among various countries like U.S.A., Europe, Korea and Australia. Especially NCAP scores affect to sales of vehicles. So vehicle makers are trying to get good score in NCAP. Low leg injuries play an important role in Australia and Euro NCAP and these injuries are related with footrest design. Optimization of footrest design in early stage of vehicle development is necessary to obtain better and robust results of low legs during crash tests. In this paper, DFSS method and finite element model were used to optimize the low leg performance in small RHD vehicles. Compared with the lower leg injury of base model, the lower leg injury of proposed model was slightly improved and robustness was enhanced also.

• 한국CDE학회논문집
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• 제14권6호
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• pp.424-433
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• 2009

In order to improve productivity and efficiency of ship production process, production technology converged with Information Technology can be considered. Mid-term scheduling based on long-term schedule of ship building and execution planning based on short-term production schedule have an important role in ship production processes and techniques. However, data used in the scheduling are from the experiences of the past, cognitive, and often inaccurate, moreover the updates of the data by formatted documents are not being performed efficiently. This paper designs the tracking and monitoring system for the curved plates forming process with shop level. At first step to it, we redefine and analyze the curved plates forming process by using SysML. From the definition and analysis of the curved plates forming process, we design the system with respect to operational view considering operational environment and interactions between systems included and scenario about operation, and with respect to system view considering functionalities and interfaces of the system. In order to study the feasibility of the system designed, a prototype of the system has been implemented with 13.56 MHz RHD hardware and application software.

• 대한의생명과학회지
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• 제2권2호
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• pp.257-265
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• 1996

토끼 바이러스성 출혈증의 원인체를 실험 토끼에 접종하여 증식을 유도하고 간장에서 hematoxylin & eosin 염 색 에서 조직학적 진단과 세포내 viral RNA의 소재를 결정하기 위해 post-unicryl 포매한 block의 절편을 사용하여 단 염색과 전자현미경적 in situ hybridization을 시도하였다. 토끼 출혈증 viral RNA의 보합 결합에 이용하는 probe는 4717에서 4800(84bases)까지 oligonucleotide를 5'말단에 biotin-CE phosphoramidite로 표지하여 사용하였다. 보합결합물의 증명은 신호 표지로서 antibiotin antibody-l0nm gold를 사용하였으며, hybridization이나 증명은 기존 protocol에서 약간의 변법을 사용하였다. 0.02% glutaraldehyde에서 고정하고 unicryl resin 포매한 표본, biotinylated oligonucleotide probe, antibiotin antibody-l0nm gold로 실험한 결과 증강된 신호를 얻을 수 있었다. 특히 전처리를 생략하므로써 실험 과정을 간단하게 하여 신속한 결과를 얻을 수가 있었다. 전자현미경 in situ hybridization을 통하여 토끼 출혈증 바이러스의 주요 표적은 간세포로 감염 세포의 세포질 내 미토콘드리아와 핵 사이에서 immune gold입자가 뚜렷하게 표지 됨으로서 viral RNA를 증명할 수 있었다.

• Molecules and Cells
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• 제21권2호
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• pp.261-268
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• 2006

The Drosophila methuselah (mth) mutant has an approximately 35 percent increase in average lifespan, and enhanced resistance to various forms of stress, including starvation, high temperature, and dietary paraquat. To examine the transcriptional regulation of mth, we used luciferase assays employing Drosophila S2 cells. Two positive control elements were found at -542 ~ -272 (PE1) and +28 ~ +217 (PE2), where putative binding sites for transcription factors including Dorsal (Dl) were identified. Cotransfection of a Dl expression plasmid with a mth-luciferase reporter plasmid resulted in decreased reporter activity. PE1 and PE2, the minimal elements for strong promoter activity, were required for maximal repression by Dl protein. The N-terminal Rel homology domain (RHD) of Dl was not sufficient for repression of mth. We demonstrated by chromatin affinity precipitation (ChAP) assays in S2 cells that Dl bound to the putative PE1 binding site. Unexpectedly, semi-quantitative RT-PCR analysis revealed that the level of mth transcripts was reduced in dl flies. However, the in vivo result support the view that mth expression is regulated by dl, since it is well known that Dl functions as both a transcriptional activator and repressor depending on what other transcription factors are present. These findings suggest that both innate immunity and resistance to stress are controlled by Dl protein.

• 말소리와 음성과학
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• 제13권3호
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• pp.1-13
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• 2021

의사소통에 중요한 역할을 하는 운율은 기능에 따라 언어적 운율과 정서적 운율로 구분한다. 대뇌 편재화 관점에서 정서적 운율 처리는 우반구가 주로 담당한다는 결과가 일반론적으로 받아들여지지만, 언어적 운율에 대한 연구들은, 연구간의 방법적인 차이로 인해 결과가 상이하게 나타난다. 본 연구는 정상 화자 9명과 뇌졸중 환자 14명(좌반구 손상 7명, 우반구 손상 7명)의 세 집단을 대상으로 대뇌 편재화의 관점에서 언어적 운율 특성을 살펴보기 위해 세 가지 형태 의문문(의문사 의문문, 예-아니오 의문문, 선택 의문문)에서의 발화속도, 지속시간, 음도, 강도와 관련된 운율 특징을 청지각 평가와 함께 살펴보았다. 연구결과, 통계적으로 유의한 주요변수들이 좌반구 손상 환자의 자료에서 결함을 보였으며, 예-아니오 의문문과 선택 의문문보다 의문사 의문문에서 더욱 두드러졌다. 이러한 경향은 특히 음도와 발화속도 관련 변수들에서 두드러졌다. 본 연구의 결과는 한국어 사용자의 의문사 사용에 있어서 어휘-의미론적, 구문론적 정보와 같은 언어학적으로 관련 있는 운율 처리의 경우 우반구보다 좌반구에서 대체로 우세하다는 점을 방증한다.

• 한국에너지공학회:학술대회논문집
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• 한국에너지공학회 2002년도 추계 학술발표회 논문집
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• pp.171-184
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• 2002

우리나라 5개 정유사에서 일간 생산되는 중질잔사유 (Vacuum Residue) 량은 약 200,000 B/d이며, 일부는 Asphalt 또는 Sulfur fuel oil, 기타 탈황공정(RHD)둥에서 upgrading 되고 있다. 중질잔사유는 유황 및 중금속 물질의 함유량이 높아 가스화를 통한 효율적인 이용이 요구되고 있으며, 최근들어 효율적인 중질잔사유의 사용을 위하여 SK정유와 LG, Caltex에서 435-500 MWe IGCC 발전소 및 수소 제조공정을 위한 타당성 조사를 한 바 있다. 현재 한국에너지기술연구원에서는 습식분류상 가스화장치를 이용하여 중질잔사유가스화 특성에 관한 연구를 수행하고 있다. 실험은 반응온도 : 1,100~1,25$0^{\circ}C$, 반응압력 : 1~6kg/$ extrm{cm}^2$G, oxygen/V.R ratio : 0.8~0.9 and steam/V.R ratio : 0.4~0.5를 유지하며 수행되었으며, 실험을 통해 합성가스(CO+H$_2$) 조성 : 85~93%, 생성가스 유량 : 50~110Nm$^3$/hr., 발열량 : 2,300~3,000 ㎉/Nm$^3$, 탄소전환율 : 65~92 및 냉가스효율 = 60~70%를 얻을 수 있었다. 아울러, 평형모델을 이용하여 중질잔사유가스화 공정을 모형화 하였으며 계산결과를 실험결과와 비교하여 모델의 타당성을 검토하였다.

• 에너지공학
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• 제12권1호
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• pp.49-57
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• 2003

우리나라 5개 정유사에서 일간 생산되는 중질잔사유 (Vacuum Residue)량은 약 200.000 B/d이며, 일부는 Asphalt 또는 Sulfur fuel oil, 기타 탈황공정(RHD) 등에서 upgrading 되고 있다. 중질잔사유는 유황 및 중금속 물질의 함유량이 높아 가스화를 통한 효율적인 이용이 요구되고 있으며, 최근들어 효율적인 중질잔사유의 사용을 위하여 SK정유와 LG Caltex에서 435~500 MWe IGCC 발전소 및 수소 제조공정을 위한 타당성 조사를 한 바 있다. 현재 한국에너지기술연구원에서는 습식분류상 가스화장치를 이용하여 중질잔사유가스화 특성에 관한 연구를 수행하고 있다. 실험은 반응온도: 1,100~1,25$0^{\circ}C$, 반응압력: 1~6 kg/$\textrm{cm}^2$G, oxygen/V.R ratio: 0.8~0.9 and steam/V.R ratio: 0.4~0.5를 유지하며 수행되었으며, 실험을 통해 합성가스(CO+H$_2$) 조성 : 85~93%, 생성가스 유량: 50~110 Nm$^3$/hr. 발열량: 2,300~3,000 k㎈/Nm$^3$, 탄소전환율: 65~92 및 냉가스효율: 60~70%를 얻을 수 있었다. 아울러, 평형모델을 이용하여 중질잔사유가스화 공정을 모형화하였으며 계산결과를 실험결과와 비교하여 모델의 타당성을 검토하였다.

• 대한수의학회지
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• 제52권2호
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• pp.125-131
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• 2012

Rabbit hemorrhagic disease is a highly acute and fatal viral disease caused by rabbit hemorrhagic disease virus (RHDV). Since first outbreak in Korea 1987, RHDV has been continually affected in the country, but the pattern of outbreak seem to be changed. In this study, to understand the pathogenesis of the new RHDVa serotype, we therefore carried out to inoculate RHDVa to rabbits, and to examine the sequential histopathologic changes and viral distribution. Macroscopically, various sized dark red or white spots or appearance were observed in the liver, lung, kidney uterus and ureter. In euhanized rabbits, significant pathologic findings such as infiltration of heterophils and mononuclear cells were observed at 24 hours after inoculation (HAI), and these were sequentially extended periportal to centrilobular area. However, in dead rabbits, severe hepatic degeneration and/or necrosis with relatively weak inflammatory responses were observed. RHDV antigens began to detect in liver, spleen, and lung from 12 HAI by PCR. Immunohistochemically, RHDV positive cells were seen in only liver from 24 HAI, and the degree of immunogen reactivity was stronger in dead rabbits than in euthanized ones. In conclusion, RHDVa caused the subacute or chronic infection accompanying low mortality and moderate to severe inflammatory reaction in rabbits, suggesting the possibility that RHD could become endemic.