• Title/Summary/Keyword: RG 1.195

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RADIOLOGICAL DOSE ASSESSMENT ACCORDING TO METHODOLOGIES FOR THE EVALUATION OF ACCIDENTAL SOURCE TERMS

  • Jeong, Hae Sun;Jeong, Hyo Joon;Kim, Eun Han;Han, Moon Hee;Hwang, Won Tae
    • Journal of Radiation Protection and Research
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    • v.39 no.4
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    • pp.176-181
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    • 2014
  • The object of this paper is to evaluate the fission product inventories and radiological doses in a non-LOCA event, based on the U.S. NRC's regulatory methodologies recommended by the TID-14844 and the RG 1.195. For choosing a non-LOCA event, one fuel assembly was assumed to be melted by a channel blockage accident. The Hanul nuclear power reactor unit 6 and the CE $16{\times}16$ fuel assembly were selected as the computational models. The burnup cross section library for depletion calculations was produced using the TRITON module in the SCALE6.1 computer code system. Based on the recently licensed values for fuel enrichment and burnup, the source term calculation was performed using the ORIGEN-ARP module. The fission product inventories released into the environment were obtained with the assumptions of the TID-14844 and the RG 1.195. With two kinds of source terms, the radiological doses of public in normal environment reflecting realistic circumstances were evaluated by applying the average condition of meteorology, inhalation rate, and shielding factor. The statistical analysis was first carried out using consecutive three year-meteorological data measured at the Hanul site. The annual-averaged atmospheric dispersion factors were evaluated at the shortest representative distance of 1,000 m, where the residents are actually able to live from the reactor core, according to the methodology recommended by the RG 1.111. The Korean characteristic-inhalation rate and shielding factor of a building were considered for a series of dose calculations.

The Role of Dopaminergic Fibers on the Action of Psychotropic Drugs in 6-OHDA-treated Rats (6-OHDA 파괴 후 수종의 향정신약물의 작용에 대한 중추도파민 신경계의 역할)

  • 이순철;유관희
    • Journal of Ginseng Research
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    • v.17 no.3
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    • pp.187-195
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    • 1993
  • We have examined the functional role of central dopaminergic processes on the behavioral pharmacological effects induced by psychotropics and red ginseng saponins of normal rats and compared with that of brain damaged rats. Desipramine and clomipramine produced, a significant depression of the locomotor activity in normal rats, but in brain damaged rats, they did not have any effect throughout the experimental period of 4 hours. Total saponin (50~200 mg/kg), PT (25~50 mg/kg), PD (25~50 mg/kg), $Rg_1$(12.5~25 mg/kg), $Rb_1$ (12.5~50 mg/kg) did not change, and high concentrations of PT (100 mg/kg), PD (100 mg/kg) and $Rg_1$ (50 mg/kg) showed a significant decrease in the locomotor activity of one hour after administration but total saponin (100 mg/kg), PD (25~50 mg/kg), Rgl (12.5 mg/kg), $Rb_1$ (12.5 mg/kg) markedly increased the locomotor activity of four hour after administration in normal rats. On the other hand, total saponin (50 mg/kg), PT (100 mg/kg) and PD (100 mg/kg) Produced a prominent stimulation of the locomotor activity in brain damaged rats. These results suggest that the inhibition of the locomotor activity induced by antidepressants was not affected by the sensitivity of cerebral DA system, whereas red ginseng saponin showed antifatigue effect and also the stimulation of the locomotor activity induced by red ginseng saponin was mediated by the inhibition of cerebral DA system. These psychotropic action of red ginseng saponins could be responsible for the beneficial effects on conditions of fatigue and decreased alertness.

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