• 대한전자공학회:학술대회논문집
• /
• 대한전자공학회 2000년도 추계종합학술대회 논문집(1)
• /
• pp.345-348
• /
• 2000

In this paper, A Feedforward Linear Power Amplifier for IMT-2000 which IMD characteristics was improved was designed and fabricated. To improve the main power amplifier IMD characteristics, the Feedback loop was added to basic Feedforward Power Amplifier structure. Therefore, the output power of error amplifier can be reduced, and it is easy to control the linearization circuit to cancel total IMD. The designed power amplifier represented the 40㏈m(l0W) output power and -55㏈C 3rd IMD at Center frequency 2.14㎓ (@5㎒).

• 동의신경정신과학회지
• /
• 제10권1호
• /
• pp.17-38
• /
• 1999

The effects of Sahyangsohapwon on the affective reactivity of rats were studied with open-field behavior. Sample group was treated with the medicine for 8 weeks, whereas control group was treated with the vehicle. The effects of Sahyangsohapwon on the enhancement of learning and memory of AD model rats were studied with two-way avoidance task. Sample group electrically lesioned on nbM(nucleus basalis of Meynert) was treated with the medicine for 8 weeks, whereas control group with nbM lesion and sham group with the sham operation were treated with the vehicle. 1. In the open-field behavior task, the start latency from start box was measured $27.08{\pm}7.51sec$ in control group, $23.15{\pm}5.98sec$ in sample group. Rats in sample group showed a tendency of shortened latency going out to a strange place compared with those in control group, but with no statistical significance(p>0.05). 2. In the open-field behavior task, the number of locomotion crossing the grid lines was measured $84.54{\pm}3.55$ in control group, $116.93{\pm}6.41$ in sample group. There was an increased locomotion in sample group compared with control group with statistical significance(p<0.01). This can be interpreted as rats in sample group showed lowerd anxiety under a strange environment. 3. In the open-field behavior task, the rearing number was measured $7.46{\pm}0.57$ in control group, $10.13{\pm}0.95$ in sample group. There was an increased rearing in sample group compared with control group with statistical significance(p<0.05). This can also be interpreted as rats in sample group showed lowerd anxiety under a strange environment. 4. In the open-field behavior task, the number of crossing behavior was measured $5.54{\pm}1.50$ in control group, $9.20{\pm}1.67$ in sample group. There was a increasing tendency of crossing behavior in sample group compared with control group, but with no statistical significance(p<0.05). 5. In the open-field behavior task, the total activity was measured $97.54{\pm}4.70$ in control group, $136.27{\pm}792$ in sample group. There was an increased total activity in sample group compared with control group with statistical significance(p<0.01). This can also be interpreted as rats in sample group showed lowerd anxiety under a strange environment. 6. In the analysis of effects on the learning and memory in AD model rats with two-way avoidance task, the response latency was measured $6717{\pm}134msec$ in the 1st session, $5416{\pm}160msec$ in the 2nd session, $5252{\pm}148msec$ in the 3rd session in control group. It was measured $6724{\pm}155msec$ in the 1st session, $4642{\pm}139msec$ in the 2nd session, $4914{\pm}148msec$ in the 3rd session in sample group and $4357{\pm}144msec$ in the 1st session, $3125{\pm}115msec$ in the 2nd session, $3091{\pm}98msec$ in the 3rd session in sham group. There were differences between sham group and nbM lesioned groups with statistical significance in post hoc analysis(p<0.000). And in the 2nd session, there was a reduction of latency in sample group compared with control group with statistical significance (p<0.000). This showed that sample group had better learning capacity than control group. 7. In the analysis of effects on the learning and memory in AD model rats with two-way avoidance task, the number of avoidance response was measured $5.85{\pm}1.41$ in the 1st session, $14.23{\pm}2.89$ in the 2nd session, $15.69{\pm}2.56$ in the 3rd session in control group. It was measured $7.92{\pm}1.94$ in the 1st session, $16.83{\pm}2.29$ in the 2nd session, $15.42{\pm}2.81$ in the 3rd session in sample group and $14.38{\pm}1.62$ in the 1st session, $22.88{\pm}0.89$ in the 2nd session, $23.88{\pm}1.64$ in the 3rd session in sham group. There were differences between sham group and nbM lesioned groups with statistical significance in post hoc analysis(p<0.001). But between control and sample group, there was no significant difference. With the experimental results above, Sahyangsohapwon can be supposed to have the enhancing effects on the affect reactivity and learning with memory of AD model rats induced by electrolyte injury of nbM.

• Journal of Gastric Cancer
• /
• 제21권4호
• /
• pp.418-425
• /
• 2021

Purpose: We designed a new regimen by combining intraperitoneal (IP) paclitaxel (PTX) with systemic S-1 plus oxaliplatin (SOX) for the treatment of advanced gastric cancer with peritoneal metastasis. This dose-escalation study aimed to determine the maximum tolerated dose (MTD) and recommended dose (RD) of IP PTX administered weekly to patients. Materials and Methods: Eight cycles of IP PTX plus SOX regimen were administered to the patients. S-1 was administered orally twice daily at a dose of 80 mg/m²/day for 14 consecutive days, followed by 7 days of rest. Intravenous oxaliplatin was administered at a fixed dose of 100 mg/m² on day 1, while IP PTX was administered on days 1 and 8. The initial dose of IP PTX was 40 mg/m², and the dose escalation was set in units of 20 mg/m² up to 80 mg/m². Dose-limiting toxicities (DLTs) were defined as grade 3 non-hematologic toxicities, grade 4 leukopenia, grade 3 febrile neutropenia, and grade 3 thrombocytopenia. Results: Nine patients were included in the study. No DLTs were observed in any of the enrolled patients. Therefore, the MTD was not reached, and the RD of IP PTX was determined to be 80 mg/m². Four patients (44%) showed a decreased peritoneal cancer index score on second-look laparoscopic examination. Conclusions: The present study determined the dose for further clinical trials of IP PTX to be 80 mg/m², when combined with a systemic SOX regimen.

• Applied Microscopy
• /
• 제20권1호
• /
• pp.36-50
• /
• 1990

This experiment was performed to study the morphological responses of the enterochromaffin cells in the duodenal mucosa of rabbit following bile duct ligation. Adult male rabbits were divided into normal, sham operation and experimental groups. Bile duct ligation was performed under ether anesthesia and animals were sacrificed on the 1st, 3rd, 5th, 7th and 14th day after operation. Mucosal specimens from the duodenum were prefixed with 2.5% glutaraldehyde-1.5% paraformaldehyde(0.1M Millonig's phosphate buffer, pH 7.3), followed by postfixation with 1% osmium tetroxide(0.1M Millonig's phosphate buffer, pH 7.3), and embedded within araldite mixture. The sections were cut on a LKB-V ultratome, and observed under a JEM 100CX II electron miroscope. The results were as follow; 1. Irregularities of the nuclei of the enterochromaffin cells were noticed from the 1st day after bile duct ligation, and concentration of the chromatin in the nucleus was more frequently observed on the 7th and the 14th day. 2. The granular endoplasmic reticulum and Golgi complex of the enterochromaffin cell were more developed than those of the normal on the 1st day after bile duct ligation, but they showed poor organization from the 3rd day. 3. Amount of the microfilaments in the enterochromaffin cell was significantly increased from the 5th day after bile duct ligation and they were more frequently observed in the vicinity of the nucleus. 4. Vacuoles with various electron densities in the enterochromaffin cell were increased in number from the 3rd day after bile duct ligation. 5. Glycogen-like particles in the enterochromaffin cell were frequently observed on the 3rd and the 5th day after bile duct ligation. 6. In the early stage of the ligation of bile duct, in the enterochromaffin cells, well developed intracellular organelles, such as granular endoplasmic reticulum and Golgi apparatus were pronounced. But, in the later stage, the cells contained poor organelles, with the some structural sign of necrotic change.

• 한국농업기계학회:학술대회논문집
• /
• 한국농업기계학회 2000년도 THE THIRD INTERNATIONAL CONFERENCE ON AGRICULTURAL MACHINERY ENGINEERING. V.III
• /
• pp.613-622
• /
• 2000

Watering operation for oyster mushroom growing houses is regarded as drudgery and time consuming farm operation for growers. Most of mushroom growing beds in oyster mushroom growing houses are designed as two-row with four floor beds, therefore the watering and ventilation between the bed floors are much difficult for farmers because of its structural design. The study aimed to reduce the watering operation and improve the mushroom growing environment through the humidification and air supply on mushroom growing beds. Results showed that appropriate size of nozzle is between 0.8~0.5ml/s for the humidification and higher than the 2.0ml/s for the watering. The optimum water supply pressure was regarded as between 1.0~2.0MPa and the uniform distribution of droplet on the bed showed on air flow speed of 14m/s. The prototype was equipped with twin nozzle with. the humidification nozzle of 0.85ml/s and watering nozzle of 5.0ml/s, and the air blast fan with the air speed of 10m/sec in each air spout. In the field test in a practical scale mushroom growing house, it was well operated dependant on the set desire by a electric control unit. The machine can be practically used as air blast watering and air blast humidification for oyster mushroom growing farms without manual.

• 한국정보통신학회논문지
• /
• 제14권12호
• /
• pp.2609-2614
• /
• 2010

본 논문에서는 온도센서를 이용한 온도보상회로를 구현하였으며, 이를 이용하여 전력증폭기의 동작 온도범위인 $-30^{\circ}C{\sim}60^{\circ}C$에서 전력증폭기의 혼변조 규격을 만족할 수 있도록 하였다. 온도보상회로의 출력이 온도에 따라 170mV정도 변화하도록 하여 출력이 3W인 증폭기의 TR 게이트에 인가한 결과, $-30^{\circ}C{\sim}60^{\circ}C$에서 우측 3차 혼변조 성분이 -18.5~-26dBm, 좌측 3차 혼변조 성분이 -18.5~-35dBm으로 변화하였으며, 5차 혼변조 성분은 좌 우측 모두 -24~-26dBm으로 규격인 -17dBm이하라는 전력증폭기의 혼변조 성분 규격을 만족하는 것을 확인할 수 있었다.

• Imaging Science in Dentistry
• /
• 제34권2호
• /
• pp.99-106
• /
• 2004

Purpose: To investigate the effects of irradiation on the phenotypic expression of the MC3T3-El osteoblastic cell line, especially on the osteonectin and bone sialoprotein. Materials and Methods: Cells were irradiated with a single dose of 0.5, 1, 4 and 8 Gy at a dose rate of 5.38 Gy/min using Cs-I37 irradiator. After specimens were harvested, total RNA was extracted on the 3rd, 7th, 14th, 21st day after irradiation. The total RNA was reverse-transcribed and the resulting cDNAs were subjected to amplification by PCR with a pair of primers. Results: The irradiated cells showed a dose-dependent increase in osteonectin mRNA expression when compared with the unirradiated control group. The irradiated cells showed no difference in bone sialoprotein mRNA expression when compared with the unirradiated control group. In accordance with the duration of culture period after irradiation, the level of osteonectin mRNA expression showed no difference, but it increased a little at the 21st day in the 4 and 8 Gy exposure groups. In the case of bone sialoprotein, however, the level of mRNA expression increased significantly at the 3rd and 7th day after irradiation, but it showed no difference at the 14th and 21st day when compared with the control group. Conclusion: These results showed that each single dose of 0.5, 1, 4 and 8 Gy influenced the mRNA expression of osteonectin and bone sialoprotein at the calcification stage of osteoblastic cells, suggesting that single dose of irradiation affected the osteoblastic bone formation at the cell level.

• 보건의료산업학회지
• /
• 제5권3호
• /
• pp.145-155
• /
• 2011

This study is Dental Hygiene Department of G University for comprehensive dental hygiene control and treatment weekly for four weeks from September 16 to October 20, 2010, excluding those who visited for ambulatory treatment of systemic diseases. For the 90 subjects, we performed oral examination, measured Simplified Oral Hygiene Index (S-OHI), Modified Patient Hygiene Performance (PHP-M), and O' Leary Index, and applied comprehensive dental hygiene control. First, as to the change of OHI according to age, the index in the 1st measurement was 3.43 in those under 35 and 3.17 in those aged 35 or older, so it was higher in the younger group, but in the 2nd measurement it was 1.89 in those under 35 and 2.14 in those aged 35 or older, and in the 3rd measurement it was 1.22 in those aged 35 or older, so it was higher in the older group. Second, as to the change of PHP-M according to age, the index in the 1st measurement was 50.35 in those under 35 and 43.16 in those aged 35 or older, soit was higher in the younger group, but in the 2nd measurement it was 31.97 in those under 35 and 28.88 in those aged 35 or older, and in the 3rd measurement it was 21.31 in those aged 35 or older, so it was higher in the older group.

• International Journal of Industrial Entomology and Biomaterials
• /
• 제33권2호
• /
• pp.63-67
• /
• 2016

This study examined the biological characteristics of Meganoton scribae under the following conditions: temperature (20, 25, $30^{\circ}C$), humidity ($60{\pm}10%$), and photoperiod (14L:10D). At $25^{\circ}C$, the larval stage of M. scribae lasted for 28.4 d, and the pupal stage for 15.6 d. The average head width was 0.96 mm in the $1^{st}$, 1.34 mm in the $2^{nd}$, 2.07 mm in the $3^{rd}$, 3.64 mm in the $4^{th}$, and 5.89 mm in the $5^{th}$ instar. The life span of female adults was 10.3 d, and the maximum number of eggs spawned was 257.7. The results of the study will be useful for the commercial development of M. scribae.

• Journal of the Optical Society of Korea
• /
• 제13권2호
• /
• pp.294-298
• /
• 2009

In this paper we proposed a new Bragg grating waveguide in order to improve reflectivity and to achieve compactness. Bragg gratings with various thicknesses were engraved in the middle of the core layer with a length of 3 mm. For the sake of cost-effectiveness, the $3^{rd}$ order Bragg grating waveguides were fabricated via conventional photolithography. The maximum reflectivities for the fixed width waveguide of $6{\mu}m$ with the 0.1 and $0.3{\mu}m$-thick Bragg gratings were, -13.14 and -6.25 dB, respectively, and the Bragg wavelengths were 1562.28, 1564.10 nm, respectively. A slight increase in the Bragg grating thickness can result in a remarkable reduction in the length of the Bragg grating waveguide with a fixed reflectivity.