• 제목/요약/키워드: RCT(randomized controlled trials)

검색결과 212건 처리시간 0.022초

기능성 소화불량증에 사용된 침구치료방법에 대한 체계적 문헌고찰 (A Systematic Review of Acupuncture-Moxibution Treatment for Functional Dyspepsia)

  • 김보영;서복남;박지은;양창섭;김익태;임지원;김영은
    • Korean Journal of Acupuncture
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    • 제34권1호
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    • pp.8-36
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    • 2017
  • Objectives : The aim of this study is to review the methodology of clinical trials conducted with the acupuncture and moxibustion treatment on functional dyspepsia. Methods : We searched four international databases and three Korean databases including English, Korean and Chinese, through March 2016 for randomized controlled trials(RCT) and non-randomized case-control trials(CCT) that evaluated the effects of the acupuncture and moxibustion on functional dyspepsia. We abstracted the designs of the trials and the method of acupuncture and moxibustion treatment according to the Standards for Reporting Interventions in Clinical Trials of Acupuncture. Results : A total 117 papers were reviewed. The 106 studies were conducted in China. There were 111 RCTs(95%), and 6 CCTs(5%). Sixty eight studies(59%) were conducted with the manual acupuncture, 29 studies of electro-acupuncture(25%), 11 studies of moxibustion(9%), 5 studies of acupoints embedding therapy(4%), 4 studies of acupoint injection therapy(3%) were conducted. ST36, CV12, ST25 were most frequently used for acupoints to treat functional dyspepsia. In 59 studies(50%), western medication was used in the control group, and the effects of acupuncture and moxibustion were evaluated with the symptoms in most studies. Conclusions : These results suggest that it is necessary to develop more detailed reporting standards about acupuncture and moxibustion treatment method as the method of acupuncture and moxibustion is getting more diverse, and more objective tools are needed in evaluating functional dyspepsia.

얼굴마비의 임상연구병행 경제성평가 프로토콜 개발을 위한 체계적 문헌고찰연구 (Systematic Review for the Development of the Clinical Study with Economical Assessment Protocol on Facial palsy)

  • 공나경;서은성;선지혜;김남권
    • 대한한의학회지
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    • 제38권1호
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    • pp.46-55
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    • 2017
  • Objectives: The aim of this study is reviewing the literature to extract the key parameter, study design, perspective, cost-effectiveness index and find the calibration parameter for the clinical study with economical evaluation protocol on facial palsy. Methods: Literature search is performed using PUBMED for literature published from January 2000 to December 2016. We included randomized controlled trials(RCTs) and modelling study with economic assessment in which human participated. Results: As a result of literature search, the 198 articles were found. After reviewing the title, abstract and full text, the 5 articles were selected. Selected articles are classified into 4 RCT studies dealing with quality of life and 1 CEA(cost-effectiveness analysis) study. Conclusions: We found reliable key parameters, calibration parameters and elements of economical assessment study, which might be necessary factors for developing research protocol of clinical trial with economic evaluation about facial palsy patients.

사시의 침치료에 대한 최근 임상 연구 동향 (Recent Clinical Research on Effect of Acupuncture for Strabismus)

  • 이지나;이선행;이진용
    • 대한한방소아과학회지
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    • 제30권2호
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    • pp.23-30
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    • 2016
  • Objectives The purpose of this study is to investigate recent clinical studies on effect of acupuncture for strabismus in Korea and other countries. We have analyzed 10 years (from 2006 to 2015) of case studies and randomized controlled trials (RCT) on effect of acupuncture for strabismus. Methods The search database includes Oasis, KTKP (Korean Traditional Knowledge Portal), Medline, Embase, and Cochrane library. To narrow the search, the following key search terms were used: 'strabismus, acupuncture'. The search was limited to the publication date from 2006 to 2015. 7 case studies and 5 control studies were selected for analysis. Results and Conclusions 1. The acupuncture treatment is effective for paralytic strabismus 2. The studies used BL1, GB1, ST2, TE23, GB15, EX-HN5, ST1, and LI4 acupoints and also an electroacupuncture treatment, which is 15 minutes of extraocular muscle stimulation, was used. 3. Degree of strasbismus was tested by Ocular motor range test, Corneal light reflex test, Ocular abducent scale test (Scott and Kraft, Diploptic range test).

산후 유즙분비부전에 대한 추나 치료: 체계적 문헌 고찰 및 메타분석 (Chuna Manual Therapy for Postpartum Hypogalactia: A Systematic Review and Meta-Analysis)

  • 김채영;이은별;김현지;안희덕
    • 척추신경추나의학회지
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    • 제17권1호
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    • pp.1-10
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    • 2022
  • Objectives To evaluate the effectiveness of Chuna manual therapy (CMT) for postpartum hypogalactia. Methods Using nine electronic databases, we selected 13 randomized controlled trials (RCTs) that applied CMT for postpartum hypogalactia and conducted a meta-analysis. The risk of bias was assessed using the Cochrane risk of bias tool. Results Meta-analysis showed statistically significant results for CMT in terms of effective rate and breast filling degree compared to the other treatment groups (p<0.05). Conclusions Our study showed clinical evidence of CMT efficacy for postpartum hypogalactia. Further studies are required to support our findings.

Pub Med 검색을 통한 폐경기 증상의 침구 임상시험에 대한 고찰 - 안면홍조를 중심으로 (Review on randomized controlled trials of acupuncture for postmenopausal symptoms in the search site, Pub Med. - focusing on hot flush)

  • 김로사;이진무;조정훈;장준복;이경섭;이창훈
    • 대한한방부인과학회지
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    • 제20권4호
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    • pp.148-159
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    • 2007
  • Purpose: Vasomotor symptoms including hot flash are very common to postmenopausal women. Estrogen therapy was regarded as the best option for relieving menopausal symptoms until 2002, when the Women#s Health Initiative(WHI) reported the side effect of the therapy. Consequently, studies on the complementary and alternative medical herbs and therapy for the management of menopausal symptoms have followed. And so we have reviewed some international clinical studies about the management of postmenopausal symptoms with acupuncture therapy. Methods: "Menopause and acupuncture" was designated as a key word in the search site. Pub Med, and nine papers dealing with hot flash among the relevant RCTs were selected, and then, the effect of acupuncture on hot flash and the way the researches had been done was examined. Results : The intensity of hot flash reduced significantly and the frequency of hot flash was inclined to reduce, but not significantly, compared to the controlled group. Conclusion: Each clinical test has its limitations in point of the number of the required samples. However, it still shows the possibility that acupuncture itself will be effective enough to reduce the intensity of hot flash to a certain degree. It is believed that extensive clinical tests on the effect of acupuncture on hot flash will need to be done hereafter. And when the tests are carried out, it is required to exclude placebo effect, do blind test, and carefully select and control the methods.

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요추 추간판 탈출증의 한의학적 치료에 대한 국내연구동향 (Research Trends on the Treatment of Lumbar Herniated Intervertebral Disc in Korean Medicine)

  • 조형준;설재욱;신미숙
    • Korean Journal of Acupuncture
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    • 제29권4호
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    • pp.501-518
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    • 2012
  • Objectives : To research trends of studies on treatments of lumbar herniated intervertebral disc in Korean medicine. Methods : We searched papers using Korean Traditional Knowledge Portal, OASIS, KISS. We used "low back pain", "radiculopathy", "lumbar herniated intervertebral disc" as keyword. Limitations were as follows; Domestic studies, published from 2000 to 2011, mentioning the treatments of lumbar herniated intervertebral disc in Korean medicine. This study researched and classified the papers according to the fields of the treatment and methods of study. Results : The results were obtained as below ; 1. The number of papers published in 2000 was only three, but steadily increased to 15 in 2010 and the total number of papers was 93. 2. When categorized according to the fields of treatment, 93 researches are classified as acupuncture, moxibustion, Chuna therapy, drug, various physical therapies and collaborative Oriental-Western medicine therapy. 3. When categorized according to the methods of study, 70 researches were the simple case report and non-RCT(non-randomized controlled trial) were 11 and RCT(randomized controlled trials) has been reported in 11 researches. 4. General assessment tools were VAS, ODI before, however these days, Physical examination(ROM, SLRT, etc.), Radiologic tests(MRI, X-ray), DITI etc. are used more in order to evaluate objective therapeutic effects. Conclusions : These results indicate that researches on lumbar herniated intervertebral disc in Korean medicine have been investigated by various method and steadily increasing.

신체화 장애에 대한 중의학 연구동향 (A Review on Treatment of Somatization Disorder in Traditional Chinese Medicine)

  • 김효섭;배진수;이승환;임정화;성우용
    • 동의신경정신과학회지
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    • 제28권3호
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    • pp.217-230
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    • 2017
  • Objectives: This study was conducted to review studies on somatization disorder in traditional Chinese medicine. Methods: We reviewed studies in the China National Knowledge Infrastructure (CNKI) to 2017. Keywords were 軀體化障碍, Somatization disorder, somatic symptom disorder. We included Randomized Controlled Trial (RCT), and excluded non-Randomized Controlled Trial (nRCT), non-related somatization disorder or traditional Chinese medicine, non-clinical trials, dissertations for degrees. Jadad scale and Cochrane Library's Risk of Bias (RoB) were used for assessment of the quality of studies. Results: Twelve studies were selected. The Chinese Classification of Mental Disorders-3 (CCMD-3) was most frequently used as diagnostic criteria for somatization disorder. As for outcome measurement, Hamilton Rating Scale for Depression (HAMD) was used most commonly. Meta-analysis of 10 studies revealed effective rate of Chinese Herbal Medicine groups (CHM) was significantly higher than Western Medicine groups (WM) (RR: 1.14, 95% CI: 1.02 to 1.27, p=0.02, $I^2=40%$). There was no significant difference in effective rate of CHM+WM and WM (RR: 1.12, 95% CI: 0.84 to 1.49, p=0.46, $I^2=83%$). And also, effective rate of Acupuncture group (Acu) revealed no significant difference compared to that of WM (RR: 1.17, 95% CI: 0.95 to 1.44, p=0.13, $I^2=84%$). For HAMD, there was significant difference in CHM vs, WM group and Acu vs. WM group. Quality of selected 12 RCTs was low. Conclusions: Therapies practiced in traditional Chinese medicine may be effective options for somatization disorder. treatment. For further clinical studies in Korean medicine, this study could be groundwork for development of diagnosis and treatment on somatization disorder.

갱년기 우울증에 대한 중약 중재 임상연구 고찰 -CNKI에서 검색된 무작위배정 비교임상시험을 중심으로 (Review of Clinical Studies on the Treatment of Menopausal Depression Using Traditional Chinese Medicine -Focusing on Randomized Controlled Trial in CNKI)

  • 최성률;정성엽;홍두현;유진실;최종호;김미혜
    • 동의신경정신과학회지
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    • 제31권1호
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    • pp.49-61
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    • 2020
  • Objectives: The objective of this study is to analyze clinical reports of treatment of menopausal depression in traditional Chinese medicine (TCM). Methods: This study included randomized controlled trials (RCT) in treating menopausal depression. Literature studies of Chinese National Knowledge Infrastructure Database(CNKI) were performed. Clinical reports on menopausal depression treatment were searched using the following key words in the CNKI: 'menopausal depression' and 'postmenopausal depression'. Results and Conclusions: A total of 24 RCT articles on menopausal depression were selected. The most widely used diagnostic tool for menopausal depression was CCMD-3. Effective rate and HAMD were the most commonly used assessment tools. Bosinhaeultang-gagam (Bushenjieyu-tang jiajian) and Gami-gammaegdaejotang(Jiawei ganmaidazao-tang) were used much more than other prescriptions, while Bupleuri Radix was the most used single medicine herb. Additionally, the Chinese medicine treatment group showed less adverse reactions than the control group. As a result, we could know frequently used herbal prescription and single medicinal herbs and this can be helpful in developing more advanced studies in future.

비급성 요통에 대한 무작위대조군 임상연구 수행을 위한 추나표준화 설문조사 보고 (The Survey on the Standardization of Chuna Manual Technique for Operating RCT of Non-acute Low Back Pain)

  • 김병준;황의형;허광호;황만석;허인;송윤경;이정한;고연석;박태용;조재흥;이은정;문수정;하인혁;이민호;신병철
    • 척추신경추나의학회지
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    • 제10권2호
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    • pp.13-25
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    • 2015
  • Objectives : To find out the standardized chuna manual technique for non-acute low back pain. Methods : The survey questions were developed by the consensus from the professor who major in Rehabillitation Medicine of Korean Medicine(RMKM). August 15th to september 1st 2015, the questionnaire was given to 23 RMKM doctors by e-mail. 20(90.9%) the questionnaire were retrieved out. Standardized technique of chuna were selected through experts consesus based on questionaire results. Results : Two essential techniques and two selective techniques were selected as standardized Chuna manual technique for lumbar region. Six essential technique and one selective technique were selected as standardized Chuna manual technique for iliac region. Conclusions : This is the first consensus of experts opinion for Chuna manual technique for operating randomized controlled trials(RCT). These reports are helpful for Korean Medicine doctor who operate Chuna manual technique and expected to make clinical evidence of Chuna manual medicine

소아 천식 치료의 국외 보완대체의학 임상 연구 동향 (The Trends in Foreign Clinical Trials for Pediatric Asthma in Complementary and Alternative Medicine)

  • 방미란;김장현;민상연
    • 대한한방소아과학회지
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    • 제29권3호
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    • pp.1-11
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    • 2015
  • Objectives : The purpose of this study is to analyze the trends in foreign clinical trials for pediatric asthma in complementary and alternative medicine (CAM). Methods : We reviewed 31 randomized controlled trials (RCT) for pediatric asthma treatment in CAM published from 2005 to 2015 in PubMed and analyzed their treatments, compounds of herbal medicines, acupoints, methods of assessment, and treatment results. Results : The treatments used in the studies were herbal medicines, acupuncture, acupoint application, breathing training, supplement, normocaloric diet, yoga, massage therapy, and art therapy. The frequently used herbs were Asari Herba Cum Radix (細辛). Ephedrae Herba (麻黃), Astragali Radix. The most common acupoints were Feishu (肺兪, BL13). The methods of assessment in pediatric asthma were symptom scale, questionnaire of Quality of Life, lung function test, laboratory studies, and medication usage. In 28 out of 31 studies, treatment group gets better than non-treated group. Conclusions : This study shows that CAM is effective in treating pediatric asthma. More clinical studies using objective outcome measures are needed to prove its efficacy clearly.