• Journal of Intelligence and Information Systems
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• v.10 no.2
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• pp.53-63
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• 2004

Recurrent-Cascade-Correlation(RCC) is a supervised teaming algorithm that automatically determines the size and topology of the network. RCC adds new hidden neurons one by one and creates a multi-layer structure in which each hidden layer has only one neuron. By second order RCC, new hidden neurons are added to only one hidden layer. These created neurons are not connected to each other. We present a generalization of the RCC Architecture by combining the standard RCC Architecture and the second order RCC Architecture. Whenever a hidden neuron has to be added, the new RCC teaming algorithm automatically determines whether the network topology grows vertically or horizontally. This new algorithm using sigmoid, tanh and new activation functions was tested with the morse-benchmark-problem. Therefore we recognized that the number of hidden neurons was decreased by the experiments of the RCC network generalization which used the activation functions.

• Computers and Concrete
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• v.33 no.4
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• pp.445-469
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• 2024

The Federal Highway Administration (FHWA) has recommended the use of AASHTOWare Pavement Mechanistic-Empirical Design (PMED) software for Roller-Compacted Concrete (RCC) pavement design, but specific calibration for RCC is missing. This study investigates the software's capacity to predict the long-term performance of RCC roadways within the framework of conventional concrete pavement calibration. By reanalyzing existing RCC projects in several U.S. states: Colorado, Arkansas, South Carolina, Texas, and Illinois, the study highlights the need for specific calibration tailored to the unique characteristics of RCC. Field observations have emphasized occurrence of early distresses in RCC pavements, particularly transverse-cracking and joint-related issues. Despite data challenges, the AASHTOWare PMED software exhibits notable correlation between its long-term predictions and actual field performance in RCC roadways. This study stresses that RCC applications with insufficient joint spacing and thickness are prone to premature cracking. To enhance the accuracy of RCC pavement design, it is essential to discuss the inclusion of RCC as a dedicated rigid pavement option in AASHTOWare PMED. This becomes particularly crucial when the rising popularity of RCC roadways in the U.S. and Canada is considered. Such an inclusion would solidify RCC as a viable third option alongside Jointed Plain Concrete Pavements (JPCP) and Continuously Reinforced Concrete Pavements (CRCP) for design and deployment of rigid pavements. The research presents a roadmap for future calibration endeavors and advocates for the integration of RCC pavement as a distinct pavement type within the software. This approach holds promise for achieving more precise RCC pavement design and performance predictions.

• Journal of Pathology and Translational Medicine
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• v.52 no.6
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• pp.378-385
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• 2018

Background: BRCA1-associated protein 1 (BAP1) mutations are frequently reported in clear cell renal cell carcinoma (ccRCC); however, very few studies have evaluated the role of these mutations in other renal cell carcinoma (RCC) subtypes. Therefore, we analyzed BAP1 protein expression using immunohistochemistry in several RCC subtypes and assessed its relationship with clinicopathological characteristics of patients. Methods: BAP1 expression was immunohistochemically evaluated in tissue microarray blocks constructed from 371 samples of RCC collected from two medical institutions. BAP1 expression was evaluated based on the extent of nuclear staining in tumor cells, and no expression or expression in <10% of tumor cells was defined as negative. Results: Loss of BAP1 expression was observed in ccRCC (56/300, 18.7%), chromophobe RCC (6/26, 23.1%), and clear cell papillary RCC (1/4, 25%), while we failed to detect BAP1 expression loss in papillary RCC, acquired cystic disease-associated RCC, or collecting duct carcinoma. In ccRCC, loss of BAP1 expression was significantly associated with high World Health Organization (WHO)/International Society of Urological Pathology (ISUP) grade (p=.002); however, no significant correlation was observed between loss of BAP1 expression and survival in ccRCC. Loss of BAP1 expression showed no association with prognostic factors in chromophobe RCC. Conclusions: Loss of BAP1 nuclear expression was observed in both ccRCC and chromophobe RCC. In addition, BAP1 expression loss was associated with poor prognostic factors such as high WHO/ISUP grade in ccRCC.

• The Korean Journal of Urological Oncology
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• v.16 no.3
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• pp.119-125
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• 2018

Purpose: We compared subtypes of papillary renal cell carcinoma (pRCC; types 1 and 2) and clear cell renal cell carcinoma (ccRCC) in patients with T1-stage RCC to analyze the impact of the subtype on oncological outcomes. Materials and Methods: This paper reviewed 75 patients with pRCC and 252 patients with ccRCC at T1-stage from 1998-2012. Thus, we assessed the impact of subtype on oncologic outcomes among patients with T1-stage RCC. We used Kaplan-Meier analysis to estimate the overall survival and recurrence-free survival The median follow-up duration was 95 months (interquartile range, 75.4-119.3 months). Results: The 5-year recurrence-free survivals of pRCC and ccRCC were 95.4% and 97.6%, respectively. pRCC is worse than ccRCC in terms of recurrence-free survival (p=0.008) and there was no significant difference in the overall survival between pRCC and ccRCC (p=0.32). In addition, there was no significant statistical difference between type 1 pRCC and type 2 pRCC in terms of either recurrence-free survival (p=0.526) or overall survival (p=0.701). Age (hazard ratio [HR], 1.069; p<0.001) and recurrence (HR, 4.93; p<0.001) were predictors of overall survival. Only tumor size (HR, 1.071; p=0.004) was predictors in the case of cancer specific survival in the multivariate analysis. Conclusions: Among patients with T1-stage RCC, recurrence after surgery was more common in pRCC than ccRCC. The subtype of pRCC (types 1 and 2) had no impact on the recurrence-free survival or overall survival.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.553-556
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• 2008

This study analyzed is to investigate the effect of the combined use of fly ash and coarse particle cement(RCC) collected in particle classification method during ordinary portland cement(OPC) on the fundamental properties of concrete. Totally 16 batches of the concrete was fabricated vary the contends of FA and RCC. As results of experiment, in the case of flow, the more the contents of RCC, the larger the flow. And the more the contents of FA displacement rate increased, the less the flow. As for simple adiabatic temperature rise due to the RCC and FA contents, it decreased with the increase of them. And particularly in the case of RCC 30% + FA 30%, temperature rise amount, was very low. Compressive strength decreased in proportion to increase of the contents of FA and RCC. And strength ratio of the concrete incorporating FA and RCC for plain concrete at 28 days was 88%${\sim}$98%, which was relatively good results.

• International Journal of Concrete Structures and Materials
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• v.4 no.1
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• pp.45-49
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• 2010

The roller compacted concrete (RCC) is supposed to be isotropic, whereas the compaction of this material, which is achieved using the same machines used for the soil, appears only unidirectional, making the RCC an anisotropic material. In this experimental work, the influence of the phenomenon of compaction on the isotropy of the RCC is studied. This study was carried out through an evaluation of the compressive strengths and ultrasonic tests which were used for measurements of the elastic modulus and the dynamic Poisson's ratio of the RCC as well as a qualitative judgement of the RCC aspect at the hardened state. The results of this work proved the anisotropy of the RCC and they showed the sensitivity of the mechanical strengths and the elastic modulus to the compaction direction.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.41 no.6
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• pp.663-671
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• 2016

According to rapidly increasing of network traffics, necessity of high-speed router also increased. For various purposes, like traffic statistic and security, traffic measurement function should performed by router. However, because of the nature of high-speed router, memory resource of router was limited. RCC proposed a way to measure traffics with high speed and accuracy. Additional quadratic probing hashing table used for accumulating elephant flows in RCC. However, in our experiment, quadratic probing performed many overheads when allocated small memory space or load factor was high. Especially, quadratic requested many calculations in update and lookup. To face this kind of problem, we use a cuckoo hashing which performed a good performance in update and loop for enhancing the RCC. As results, RCC with cuckoo hashing performed high accuracy and speed even when load factor of memory was high.

• Korean Journal of Radiology
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• v.22 no.12
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• pp.1996-2005
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• 2021

Objective: To investigate the multidetector computed tomography (MDCT) features of fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) with germline or somatic mutations, and compare them with those of papillary type II RCC (pRCC type II). Materials and Methods: A total of 24 patients (mean ± standard deviation, 40.4 ± 14.7 years) with pathologically confirmed FH-deficient RCC (15 with germline and 9 with somatic mutations) and 54 patients (58.6 ± 12.6 years) with pRCC type II were enrolled. The MDCT features were retrospectively reviewed and compared between the two entities and mutation subgroups, and were correlated with the clinicopathological findings. Results: All the lesions were unilateral and single. Compared with pRCC type II, FH-deficient RCC was more prevalent among younger patients (40.4 ± 14.7 vs. 58.6 ± 12.6, p < 0.001) and tended to be larger (8.1 ± 4.1 vs. 5.4 ± 3.2, p = 0.002). Cystic solid patterns were more common in FH-deficient RCC (20/24 vs. 16/54, p < 0.001), with 16 of the 20 (80.0%) cystic solid tumors having showed typical polycystic and thin smooth walls and/or septa, with an eccentric solid component. Lymph node (16/24 vs. 16/54, p = 0.003) and distant (11/24 vs. 3/54, p < 0.001) metastases were more frequent in FH-deficient RCC. FH-deficient RCC and pRCC type II showed similar attenuation in the unenhanced phase. The attenuation in the corticomedullary phase (CMP) (76.3% ± 25.0% vs. 60.2 ± 23.6, p = 0.008) and nephrographic phase (NP) (87.7 ± 20.5, vs. 71.2 ± 23.9, p = 0.004), absolute enhancement in CMP (39.0 ± 24.8 vs. 27.1 ± 22.7, p = 0.001) and NP (50.5 ± 20.5 vs. 38.2 ± 21.9, p = 0.001), and relative enhancement ratio to the renal cortex in CMP (0.35 ± 0.26 vs. 0.24 ± 0.19, p = 0.001) and NP (0.43 ± 0.24 vs. 0.29 ± 0.19, p < 0.001) were significantly higher in FH-deficient RCC. No significant difference was found between the FH germline and somatic mutation subgroups in any of the parameters. Conclusion: The MDCT features of FH-deficient RCC were different from those of pRCC type II, whereas there was no statistical difference between the germline and somatic mutation subgroups. A kidney mass with a cystic solid pattern and metastatic tendency, especially in young patients, should be considered for FH-deficient RCC.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.2303-2307
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• 2014

Background: Renal cancer is a serious public health problem which may be under reported and registered in our setup, since the Karachi cancer registry documented only 43 cases out of 4,268 incident cancer cases over 3 year duration. Therefore we aimed to determine the clinicopathologic characteristics of adult renal tumors in our setup. Materials and Methods: The study was conducted in histopathology department, Liaquat National Hospital and included total of 68 cases of adult renal tumors over 4 years. Detailed histopathologic characteristics of tumors were analyzed. Results: Mean age of patients was 56.4 (18-84) years. Renal cell carcinoma (RCC) was the most common cell type (78%) cases; followed by transitional/urothelial carcinoma (12.5%), leiomyosarcoma (4.7%), oncocytoma (1.6%), squamous cell carcinoma (1.6%) and high grade pleomorphic undifferentiated sarcoma (1.6%). Among 50 RCC cases; 62% were conventional/clear cell RCC (CCRCC) type followed by papillary RCC(PRCC), 24%; chromophobe RCC(CRCC), 6% and sarcomatoid RCC(SRCC), 8%. Mean tumor size for RCC was 7.2 cm. Most RCCs were intermediate to high grade (60% and 40% respectively). Capsular invasion, renal sinus invasion, adrenal gland involvement and renal vein invasion was seen in 40%, 18%, 2% and 10% of cases respectively. Conclusions: We found that RCC presents at an earlier age in our setup compared to Western populations. Tumor size was significantly larger and most of the tumors were of intermediate to high grade. This reflects late presentation of patients after disease progression which necessitates effective measures to be taken in primary care setup to diagnose this disease at an early stage.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2004.11a
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• pp.191-196
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• 2004

This paper is to measure and ealuates the technical efficiency, pure technical efficiency and scale efficiency with three inputs and two outputs with the use of DEA(data envelopment analysis) in Korean RCC(Rescue Co-ordination Center/RSC(Rescue Sub-Center). Several conclusion emerge. first the average efficiency of overall technical efficiency measure about $91.03\%$ and pure technical efficiency $96.80\%$ is much large then scale efficiency $93.83\%$. It means that inefficiency has much more to do whit the inefficient utilization of resources rather then the scale of production. second, DRS(decreasing return to scale) is Tongyeong and IRS(increasing return to scale) is Incheon, Taean, Gunsan, Yeosu, Ulsan, Donghae in RCC/RSC. finally, inefficiency RCC/RSC. have to benchmarking with reference sets.