• Journal of the Korea Safety Management & Science
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• v.13 no.3
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• pp.45-53
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• 2011

The research proposes seven elimination rules of redundant gates and blocks in Fault Tree Analysis (FTA) and Reliability Block Diagram (RBD). The computational complexity of cut sets and path sets is NP-hard. In order to reduce the complexity of Minimal Cut Set (MCS) and Minimal Path Set (MPS), the paper classifies generation algorithms. Moreover, the study develops six implementation steps which reflect structural importance (SI) and reliability importance (RI) from Reliability Centered Maintenance (RCM) that a priority of using the functional logic among components is to reduce (improve) the system unavailability (or availability). The proposed steps include efficient generation of state structure function by Rare Event Enumeration (REA). Effective use of importance measures, such as SI and ill measures, is presented based on the number and the size of MCS and MPS which is generated from the reference[5] of this paper. In addition, numerical examples are presented for practitioners to obtain the comprehensive understanding of six steps that is proposed in this research.

• Tunnel and Underground Space
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• v.10 no.3
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• pp.469-474
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• 2000

In this study, RBD(Rock Blasting Design) program was developed to perform easily on plans of rock blasting. This program has abilities as follows, that is, the test blasting plan, the bench blasting plan, and the blasting vibration analysis. The value of geological property and blasting constants was offered by database, input value of variety constants repeatedly is planned out, faster and easier. And a value of input constant may be used by user for necessity.

• Journal of the Korea Institute of Military Science and Technology
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• v.14 no.6
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• pp.1049-1057
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• 2011

Today, most weapon systems operate as component systems of SoS(System of Systems) and they produce synergy effects in the battle field by interoperating. In addition, the acquisition issues on weapon systems have expanded into SoS context including sustainment analysis. Availability is the sustainment KPP(Key Performance Parameter) of weapon systems. In this paper, a simulation model is proposed to analyze the availability of SoS. The simulation model consists of 5 modules: Mission and Task, System, System RBD, Maintenance system and a simulation engine. Then it was implemented and applied to a SoS. As a result of the application, the simulation model could be applied for analyzing the availability of the SoS and provided information about critical tasks and risky component systems to complete the given mission of the SoS.

• Sleep Medicine and Psychophysiology
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• v.30 no.1
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• pp.9-12
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• 2023

Periodic limb movements during sleep (PLMS) are prevalent in various sleep disorders, such as restless legs syndrome (RLS), periodic limb movements disorder, obstructive sleep apnea (OSA), REM sleep behavior disorder (RBD), and narcolepsy. PLMS has been hypothesized to be related to the decline of dopaminergic transmission. In RLS, PLMS is suggested to be related to iron deficiency and symptom severity. PLMD is a rare sleep disorder, and the role of PLMS in PLMD has not been clearly investigated yet. PLMS in OSA, which remain after proper PAP therapy, may need further management. The clinical relevance of PLMS in RBD and narcolepsy have not been investigated thoroughly and need further studies. Whether PLMS are to be considered as a mere symptom of individual sleep disorders or not can be elucidated through studies investigating the efficacy of therapeutic approaches to reduce PLMS in various sleep disorders.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.36 no.12
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• pp.1193-1200
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• 2008

The procedure of design for reliability which consists of reliability analysis and Failure Modes and Effects Analysis(FMEA) is established and reliability assesment is performed for the nano-satellite air-launching rocket, Mirinae II. By means of using the reliability analysis result, the feasibility to insert the Mirinae II to the target orbit for given mission time under operating environment is assessed. During the reliability analysis process, the system is categorized by Work Breakdown Structure(WBS), and reliability structure is defined by both Reliability Block Diagram(RBD) and schematics of the system. FMEA is used to determine the risk priority number of components and parts. The target reliability is satisfied by changing the design of components and parts with high-risk, hence the design for reliability to put the satellite in to the target orbit safely has been performed.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.5
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• pp.1040-1048
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• 2016

Recently, the studies of integrated reliability analysis for combat systems are actively progressing. Especially, the research of integrated reliability analysis is emphasized to overcome limitations of the previous studies. In this paper, we propose a calculation technique for integrated hit probability based on front and side hit probabilities that analyzed in previous studies to improve the time-effectiveness. Also, we find out the integrated reliability of each component based on the integrated hit probability which is calculated, and we propose the method which applied the reliability block diagram technique to analyze the whole combat system of the reliability by function kills. For verifying the proposed method, we applied the proposed method to armored fighting vehicle model. The proposed method considers crew which does not considered the element in the previous study and expects to enhance the accuracy of reliability analysis and the time-effectiveness compared with the previous study.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.35 no.6
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• pp.629-633
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• 2011

Recently, systems such as aircraft, trains and ships have become larger more complex. Therefore, the reliability calculation of these systems is more difficult. This paper presents a reliability calculation algorithm for a complex system with a solution that is difficult to analyze. When the system has a very complex structure, it is very difficult to find an analytical solution. In this case, we can assess system reliability using the failure enumeration method of the reliability path. In this research, we represent the reliability block diagram by an adjacent matrix and define the reliability path. We can find any system status by the failure enumeration of the reliability path, and thus we can calculate any kind of system reliability through this process. This result can be applied to RCM (Reliability-Centered Maintenance) and reliability information-management systems, in which the system reliability is composed of the reliabilities of individual parts.

• Journal of Veterinary Science
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• v.22 no.1
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• pp.12.1-12.11
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• 2021

Background: Bats have been considered natural reservoirs for several pathogenic human coronaviruses (CoVs) in the last two decades. Recently, a bat CoV was detected in the Republic of Korea; its entire genome was sequenced and reported to be genetically similar to that of the severe acute respiratory syndrome CoV (SARS-CoV). Objectives: The objective of this study was to compare the genetic sequences of SARS-CoV, SARS-CoV-2, and the two Korean bat CoV strains 16BO133 and B15-21, to estimate the likelihood of an interaction between the Korean bat CoVs and the human angiotensin-converting enzyme 2 (ACE2) receptor. Methods: The phylogenetic analysis was conducted with the maximum-likelihood (ML) method using MEGA 7 software. The Korean bat CoVs receptor binding domain (RBD) of the spike protein was analyzed by comparative homology modeling using the SWISS-MODEL server. The binding energies of the complexes were calculated using PRODIGY and MM/GBGA. Results: Phylogenetic analyses of the entire RNA-dependent RNA polymerase, spike regions, and the complete genome revealed that the Korean CoVs, along with SARS-CoV and SARS-CoV-2, belong to the subgenus Sarbecovirus, within BetaCoVs. However, the two Korean CoVs were distinct from SARS-CoV-2. Specifically, the spike gene of the Korean CoVs, which is involved in host infection, differed from that of SARS-CoV-2, showing only 66.8%-67.0% nucleotide homology and presented deletions within the RBD, particularly within regions critical for cross-species transmission and that mediate interaction with ACE2. Binding free energy calculation revealed that the binding affinity of Korean bat CoV RBD to hACE2 was drastically lower than that of SARS-CoV and SARS-CoV-2. Conclusions: These results suggest that Korean bat CoVs are unlikely to bind to the human ACE2 receptor.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.3
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• pp.257-265
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• 2021

The COVID-19 virus is a β-genus virus that causes infection by mediating the angiotensin convertible enzyme 2 (ACE2) receptor, which is distributed in large numbers in the human respiratory tract. The disease requires effective post-management of antibody production by complete healers and vaccinators because there is no perfect remedy for the virus infection. This study aimed to develop recombinant proteins specifically responsive to neutralizing antibodies in clinical specimens and use them to develop a rapid diagnostic kit to diagnose neutralizing antibodies quickly and conveniently against the COVID-19 virus and confirm the possibility of commercialization through a performance evaluation. Rapid diagnostic kits using COVID-19 S1 RBD recombinant proteins can be applied to rapid diagnostic kits, with positive percentage agreement (PPA) and negative percentage agreement (NPA) of 100% and 98.3%, respectively, compared to the U.S. FDA-approved ELISA kits. If the performance of the rapid diagnostic kit is improved and neutralizing antibodies can be analyzed quantitatively using quantitative analysis equipment, it can be used as important data to predict immunity to the COVID-19 virus and determine additional vaccinations.

• Journal of Electrical Engineering and Technology
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• v.10 no.5
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• pp.2105-2119
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• 2015

This paper reported the experimental result of dielectric properties of Refined, Bleached and Deodorized Palm Oil (RBDPO) combined with 0-50% of Refined, Bleached and Deodorized Soybean Oil (RBDSO). The dielectric strength and relative permittivity of RBDPO/RBDSO was higher compared to mineral oil at all ranges of ratios and temperatures which indicated a positive sign for its possible use as insulating liquid in a transformer. All ratios of the RBDPO/RBDSO mixture also demonstrated lower dissipation factor compared to mineral oil at 40℃, 70℃ and 90℃. Apart from that, the kinematic viscosity for the oil mixtures shown exceeded the IEC 60296 as well as the mineral oil results. 70%RBDPO/30%RBDSO mixture ratio was chosen as the best mixing percentage after comparison was made with the mineral oil and IEC 60296 standard where the mixture accumulated the most satisfactory of dielectric properties hence making it as the potential candidate for palm and soybean-based transformer oil.