• 농촌의학ㆍ지역보건
• /
• 제27권2호
• /
• pp.67-73
• /
• 2002

집쥐가 인체 기생충 전파에 어느 정도의 역할을 하는지 그 양상을 밝히고자 전라북도 남원, 익산지역에서 포획한 집쥐의 체내 기생충 감염상을 조사하였다. 섬진강 상류 남원지역에서 32마리, 만경강 중류 익산지역에서 53마리를 채집하여 총 85마리였고, 종별로는 곰쥐(Rattus rattus) 28마리, 시궁쥐(Rattus norvegicus) 57마리였다. 결과를 요약하면 다음과 같다. 1. 남원, 익산지역의 집쥐 85마리 중 71마리(83.5%)에서 체내 기생충이 검출되었다. 2. 폐장이 회수되었던 집쥐 74마리 중 35마리(47.3%)에서 폐장에 기생하는 조직 기생충인 폐포자충(Pneumocystis carinii)이 검출되었다. 3. 전체 85마리의 가로막에서 선모충(Trichinella spiralis)을 조사하였고, 폐심장 혈관계에서 광동주혈선충(Angiostrongylus cantonensis)을 조사하였으나 한 예도 검출하지 못하였다. 4. 간을 조사한 바 85마리 중 간모세선충(Capillaria hepatica) 22례(25.9%), Taenia taeniaeformis의 유충(Cysticercus fasciolaris) 9례(10.6%), 간흡충(Clonorchis sinensis) 1례(1.2%)가 검출되었다. 5. 장내용물을 조사 한 바 85 마리 중 50례(58.9%)에서 윤충 및 원충이 검출되었다. 윤충은 쥐조충(Hymenolepis diminuta), 극구흡충류(Echinostoma sp.), 쥐요충류(Syphacia sp.), 분신충류(Strongyloides sp.) 등이었고 원충은 대장아메바(Entamoeba coli) 등이었다. 이상의 결과에서 인수공통 질환을 일으킬 수 있는 폐포자충, 쥐조충, 간흡충 등이 집쥐에 감염되어 있어 철저한 집쥐 관리가 요망된다.

• Genomics & Informatics
• /
• 제3권2호
• /
• pp.52-54
• /
• 2005

Visualization of the homology information is an important method to analyze the evolutionary and functional meanings of genes. With a database containing model genomes of Homo sapiens, Mus muculus, and Rattus norvegicus, we constructed a web­based comparative analysis tool, BioCovi, to visualize the homology information of mammalian sequences on a very large scale. The user interface has several features: it marks regions whose identity is greater than that specified, it shows or hides gaps from the result of global sequence alignment, and it inverts the graph when total identity is higher than the threshold specified.

• The Korean Journal of Ecology
• /
• 제27권3호
• /
• pp.133-139
• /
• 2004

형산강 수계 주변을 대상으로 하여 소형 포유류의 서식현황 및 서식지 선호도를 측정하기 위하여 2003년 1월부터 7월에 걸쳐 조사하였다. 서식이 확인된 소형 포유류는 등줄쥐(Apodemus agrarius), 시궁쥐(Rattus norvegicus), 멧밭쥐(Micromys minutus) 등 3종이었다. 주요 우점종으로는 88개체로 79.20%를 보인 등줄쥐였으며, 다음으로 시궁쥐와 멧밭쥐의 순을 보였다. 소형 포유류의 서식지 선호도는 수계 주변의 토지이용 유형과 경작지, 식생유형, 그리고 제방의 설치 유무와 수심 등 여러 가지 서식지 구조에 따라 다양하게 나타났는데 민가와 삼림에 비하여 경작지에서 특히 논에서의 선호도가 높았으며, 식생 구조별로는 초지의 선호도가 높게 나타났다. 하천제방의 유무도 소형 포유류의 서식에 영향을 미쳤는데 제방이 조성되지 않은 지역이나 자연석 매트 공법으로 이루어진 지역의 경우 소형 포유류의 서식에 부정적인 영향을 미치지 않는 것으로 조사되었으나, 콘크리트 호안제방의 경우 이들의 공간적 분포에 상당한 영향을 미치는 것으로 나타났다. 수계 가장자리의 수심 또한 소형 포유류의 서식에 영향을 미쳤는데 수심이 말아질수록 소형 포유류의 서식밀도는 높게 나타났다.

• Parasites, Hosts and Diseases
• /
• 제55권3호
• /
• pp.351-355
• /
• 2017

Hymenolepis nana and Hymenolepis diminuta are globally widespread zoonotic cestodes. Rodents are the main reservoir host of these cestodes. Brown rats (Rattus norvegicus) are the best known and most common rats, and usually live wherever humans live, especially in less than desirable hygiene conditions. Due to the little information of the 2 hymenolepidid species in brown rats in China, the aim of this study was to understand the prevalence and genetic characterization of H. nana and H. diminuta in brown rats in Heilongjiang Province, China. Total 114 fecal samples were collected from brown rats in Heilongjiang Province. All the samples were subjected to morphological examinations by microscopy and genetic analysis by PCR amplification of the mitochondrial cytochrome c oxidase subunit 1 (COX1) gene and the internal transcribed spacer 2 (ITS2) region of the nuclear ribosomal RNA gene. In total, 6.1% (7/114) and 14.9% (17/114) of samples were positive for H. nana and H. diminuta, respectively. Among them, 7 and 3 H. nana isolates were successfully amplified and sequenced at the COX1 and ITS2 loci, respectively. No nucleotide variations were found among H. nana isolates at either of the 2 loci. Seventeen H. diminuta isolates produced 2 different COX1 sequences while 7 ITS2 sequences obtained were identical to each other. The present results of H. nana and H. diminuta infections in brown rats implied the risk of zoonotic transmission of hymenolepiasis in China. These molecular data will be helpful to deeply study intra-specific variations within Hymenolepis cestodes in the future.

• 대한수의학회지
• /
• 제39권5호
• /
• pp.896-907
• /
• 1999

The morphometrical characteristics such as external measurements and mandible size assessment in mice and rats have to be highly heritable and sufficiently variable between strains in order to calculate a strain specific profiles. The coat color of Korean wild rats were observed and morphometric analysis of external measurements were carried out on Korean wild rats compared to laboratory strains in order to clarify the genetic characteristics of Korean wild rats and to establish background data as a domestication of Korean wild rats for new laboratory strain. Korean wild rats were captured from Chunchon and Hoengsong. 4 inbred and 1 outbred strains of rats were used in this study for the comparison of genetic characteristic of Korean wild rats. Total body length, head length, tail length, hind foot length and ear length were measured and then statistical analysis were carried out by discrimiant analysis. The coat color of Korean wild rat showed golden white in ventral portion and dark agouti in dorsal portion. Korean wild rats could be distinguished from the other laboratory strains distinctly by morphogenetical analysis. There was significant variations among Korean wild rat compared to those of the other laboratory strains of rat. This study may provide that Korean wild rats have a unique genetic characterization compared to those of other inbred strains of rats based on morphogenetical characteristics by external measurements.

• 대한수의학회지
• /
• 제39권3호
• /
• pp.531-537
• /
• 1999

The present study was carried out to investigate the pathogenicity and pathogenesis of wild rats(Rattus norvegicus), trapped in nature, intranasally infected with Aujeszky's disease virus(ADV/NYJ-1-87) by histopathology, immunohistochemistry and in situ hybridization(ISH). Fifteen rats inoculated intranasally were roughened haircoat, anorexia, listlessness, and depression second day after inoculation, and three rats died in 66-72 hours. Eight rats showed severe pruritus at the face that was accompanied by frequent face-washing movements of the forelegs, and then became violent and spasmodic for an hour or until they died. Four rats slowly recovered after showing mild clinical signs of the disease. Microscopic lesions in infected rats were characterized by meningitis, perivascular round cell infiltration, focal gliosis, and neuronal degeneration and necrosis. And intranuclear inclusion bodies were frequently detected in the cerebral cortex and medulla. Positive reaction to ADV by immunohistochemistry and ISH were detected in the following areas : trigermimal ganglion, brain, tonsil, nasal mucosa, spleen, lung and liver. The result has suggested that ADV intranasally infected in wild rats is followed by replication in epithelial calls of nasal mucosa and tonsil, then invade local lymph nodes by way of the lymphatics. It is also believed that the virus invades bipolar olfactory cells and trigerminal ganglion; and then spread into central nervous system.

• 대한수의학회지
• /
• 제61권4호
• /
• pp.39.1-39.6
• /
• 2021

The classification of the bone pieces excavated from Gasan-ri archaeological site 1 in Jinju, presumed to be relics was investigated macroscopically. The remains of the animal bone were 3 classes (Mammalia, Aves, Amphibia), 5 orders (Carnivora, Artiodactyla, Galliformer, Rodentia, Salientia), and 6 species (Sus scrofa, Cervidae sp., Nyctereutes procyonides, Phasianidae, Rattus norvegicus caraco, Rana nigromaculata). The total weight of the animal bone remains was 1,002.80 g, with the identified bones comprising 975.30 g and an identification rate of 97.26%. A total of 447 animal bone fragments were identified, including 204 bone pieces of S. scrofa (468.00 g, 47.99%), 102 bone pieces of Cervidae sp. (453.79 g, 46.53%), 68 bone pieces of R. nigromaculata (4.69 g, 0.48%), 59 bone pieces of N. procyonides (47.14 g, 4.83%), 9 bone pieces of Phasianidae (0.98 g, 0.10%), and 5 bone pieces of Rattus norvegicus caraco (0.70 g, 0.07%). The bone pieces of the animal relics consisted of 81 skull (18.12%), 161 axial skeleton (36.02%), 64 forelimb (14.32%), and 141 hindlimb (31.54%) fragments. The archaeological significance of the animal bones excavated in this investigation was that wild boars and deer were presumed to have been mainly used animals in the Gasan-ri area of Jinju during the Three Kingdoms period.

• Restorative Dentistry and Endodontics
• /
• 제46권4호
• /
• pp.48.1-48.10
• /
• 2021

Objectives: This study aimed to evaluate the effects on bone repair of different concentrations of mineral trioxide aggregate (MTA) added to AH Plus. Materials and Methods: Bone tissue reactions were evaluated in 30 rats (Rattus norvegicus) after 7 and 30 days. In the AH + MTA10, AH + MTA20, and AH + MTA30 groups, defects in the tibiae were filled with AH Plus with MTA in proportions of 10%, 20% and 30%, respectively; in the MTA-FILL group, MTA Fillapex was used; and in the control group, no sealer was used. The samples were histologically analyzed to assess bone union and maturation. The Kruskal-Wallis and Mann-Whitney tests were performed for multiple pairwise comparisons (p ≤ 0.05). Results: At the 7-day time point, AH + MTA10 was superior to MTA-FILL with respect to bone union, and AH + MTA20 was superior to MTA-FILL with respect to bone maturity (p < 0.05). At the 30-day time point, both the AH + MTA10 and AH + MTA20 experimental sealers were superior not only to MTA-FILL, but also to AH + MTA30 with respect to both parameters (p < 0.05). The results of the AH + MTA10 and AH + MTA20 groups were superior to those of the control group for both parameters and experimental time points (p < 0.05). Conclusions: The results suggest the potential benefit of using a combination of these materials in situations requiring bone repair.

• The Korean Journal of Ecology
• /
• 제11권1호
• /
• pp.17-28
• /
• 1988

Five hundrad and eight rats were caught in Shiheung-dong and Mt. Kwan-ak from 1986 to 1987 in this survey. Ectoparasites were got from these rats and classified. The results were as follows: 9,191 mites (16 genera, 30 species), 408 fleas (4 genera, 4 species), and 521 lice (3 genera, 5 species) were observed in this survey. In the residential area, Rattus norvesicus(71.74%) was dominant species and in Mt. Kwan-ak Apodemus agrarius(93.62%). In these areas, the mites belonging to suborder Mesostigmata were dominant (Laelaps nuttli, 52.61%; Ornithonyssus bacoti, 36.05%). In Mt. Kwan-ak, family Frombiculidae belonging to suborder Prostigmata were dominant (Leptotromibidium orientalis, 31.04%; Leptotrombidium palpalis, 30.00%). In this way, it was discovered that the difference between the two regions in dominant species was noticeable. As for the hosts parasitized by mites, L. nuttalli in R. norvegicus (54.85%), L. nuttalli in R. rattus (32.90%), and L. orientalis in A. agrarius (31.27%) were dominant species, respectively. In the mites parasitizing on A. agrarius in each altitude, the species were more varied as the region was lower and the dominant species were more concentrated as it was higher.

• 한국응용곤충학회지
• /
• 제13권4호
• /
• pp.251-253
• /
• 1974

한국에 있어서 쥐로 인한 곡물의 피해는 연간 곡물총생산량의 $20\%$에 달한다. 우리나라의 쥐종류는 12종으로 알려져 있으며 그중 집쥐<시궁 쥐>, 지붕쥐<곰쥐>, 생쥐 및 등줄쥐가 대표적이다. 1962년 이래 구서사업은 정부의 주관하에 실시되어 왔다. 살서제로서는 당초 항혈액의고제를 사용하였으나 예산의 제약 때문에 기대하는 결과를 얻지 못하였고 그후 1970년이후 인화아연제로 대체하여 계속사용하였던 결과 기피성으로 인하여 사업성과는 매년 떨어지고 있는 현실이다. 필자는 이러한 문제를 해결하기 위하여 $\ulcorner$파라핀옥스$\lrcorner$를 사용하여 인산아연제의 입자를 피복하여 본제의 독특한 맛을 제거하고 또한 약제의 분해를 지연시키므로서 호식성을 증가시켜 높이는데 성공하였다. 앞으로 이러한 방법이 구서사업에 도입된다면 약효를 상당화 증가시켜줄 것으로 사료된다. 그러나 보다 근본적인 구서대책을 위하여는 본 사업에 대한 국민들의 보다 많은 관심과 이에 대한 철저한 연구, 훈련 및 충분한 자금의 뒷받침이 수반되어야 할 것이다.