• Journal of Plant Biotechnology
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• v.40 no.1
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• pp.9-17
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• 2013

Ran is a small GTP-binding protein that binds and subsequently hydrolyzes GTP. The functions of Ran in nuclear transport and mitotic progression are well conserved in plants and animals. In animal cells, stress treatments cause Ran relocalization and slowing of nuclear transport, but the role of Ran proteins in plant cells exposed to stress is still unclear. We have therefore compared Ran genes from three EST libraries construed from different cell types of sweetpotato and the distribution pattern of Ran ESTs differed according to cell type. We further characterized two IbRan genes. IbRan1 is a specific EST to the suspension cells and leaf libraries, and IbRan2 is specific EST to the root library. IbRan1 showed 94.6 % identity with IbRan2 at the amino acid level, but the C-terminal region of IbRan1 differed from that of IbRan2. These two genes showed tissue-specific differential regulation in wounded tissues. Chilling stress induced a similar expression pattern in both IbRan genes in the leaves and petioles, but they were differently regulated in the roots. Hydrogen peroxide treatment highly stimulated IbRan2 mRNA expression in the leaves and petioles, but had no significant effect on IbRan1 gene expression. These results showed that the transcription of these two IbRan genes responds differentially to abiotic stresses and that they are subjected to tissue-specific regulation. Plant Ran-type small G-proteins are a multigenic family, and the characterization of each Ran genes under various environmental stresses will contribute toward our understanding of the distinctive function of each plant Ran isoform.

• Molecules and Cells
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• v.26 no.3
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• pp.270-277
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• 2008

This study addresses the physiological functions of the Ran-binding protein homolog NbRanBP1 in Nicotiana benthamiana. Virus-induced gene silencing (VIGS) of NbRanBP1 caused stunted growth, leaf yellowing, and abnormal leaf morphology. The NbRanBP1 gene was constitutively expressed in diverse tissues and an NbRanBP1:GFP fusion protein was primarily localized to the nuclear rim and the cytosol. BiFC analysis revealed in vivo interaction between NbRanBP1 and NbRan1 in the nuclear envelope and the cytosol. Depletion of NbRanBP1 or NbRan1 reduced nuclear accumulation of a NbBTF3:GFP marker protein. In the later stages of development, NbRanBP1 VIGS plants showed stress responses such as reduced mitochondrial membrane potential, excessive production of reactive oxygen species, and induction of defense-related genes. The molecular role of RanBP1 in plants is discussed in comparison with RanBP1 function in yeast and mammals.

• Electronics and Telecommunications Trends
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• v.31 no.6
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• pp.88-96
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• 2016

5G RAN은 4G가 진화된 무선기술(evolved E-UTRA)과 5G 무선기술(New Radio, NR)을 모두 지원하는 새로운 무선액세스 네트워크(New RAN)이며, 코어 네트워크 (EPC and NGC)과 접속되어 5G 시스템(NextGen System)을 구성한다. 본고에서는 5G RAN(Radio Access Network,)을 대상으로, RAN 시설 배치 시나리오, RAN과 CN 간 기능 분배 및 인터페이스, 프런트-홀 네트워크의 전송 용량 및 지연, New RAN과 E-UTRA 간 모빌리티 시나리오 등에 대한 표준 이슈를 살펴본다. 마지막 절에선 RAN의 네트워크 슬라이싱 지원 방안으로 상위레벨 개념의 구조와 절차를 정리한다. 본 문서는 3GPP RAN3 그룹의 기술보고서(TR 38.801)와 SA2 기술보고서(TR 23.799)를 바탕으로 작성되었다.

• Proceedings of the Korea Information Processing Society Conference
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• 2019.10a
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• pp.211-212
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• 2019

Slicing Radio Access Network (RAN) can help in effectively utilizing the network bandwidth and to better manage the increasing traffic over interent. RAN slicing system discussed in this paper is based on an open-source slicing mechanism in which we write a JSON configuration file for slicing policy and send it to the FlexRAN controller. FlexRAN controlls the core networks (CNs) through OAI-RAN on the evolved packet core (EPC) component of this system. Each CN is responsible for handling a saperate RAN slice. The type of internet traffic is identified by the FlexRAN crontroller and is sent to the respective CN through OAI-RAN. CN handles the traffic according to the allocated bandwidth and in this way the internet traffic is sliced inside the EPC component.

• Electronics and Telecommunications Trends
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• v.39 no.1
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• pp.14-24
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• 2024

The O-RAN Alliance is responsible for defining the technical and testing specifications of open radio access networks, aiming for openness, virtualization, and intelligence in these networks. Recently, the application of Korea Open Testing and Integration Center (OTIC) to this alliance has been approved, enabling the issuance of O-RAN certificates and badges. An OTIC plays a crucial role as a testing facility in performing conformance verification and interoperability tests for O-RAN functions and interfaces. In addition, it enables end-to-end system verification adhering to O-RAN principles and processes. These activities can substantially contribute to enhancing the competitiveness of domestic O-RAN products and activating the corresponding ecosystem. We comprehensively describe the O-RAN certification and badging processes. Additionally, we analyze end-to-end test cases that are essential for the proper deployment and operation of 5G systems including O-RANs.

• BMB Reports
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• v.47 no.11
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• pp.643-648
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• 2014

Stanniocalcin (STC), a glycoprotein hormone originally discovered in fish, has been implicated in calcium and phosphate homeostasis. While fishes and mammals possess two STC homologs (STC1 and STC2), the physiological roles of STC2 are largely unknown compared with those of STC1. In this study, we identified Ran-binding protein M (RanBPM) as a novel binding partner of STC2 using yeast two-hybrid screening. The interaction between STC2 and RanBPM was confirmed in mammalian cells by immunoprecipitation. STC2 enhanced the RanBPM-mediated transactivation of liganded androgen receptor (AR), but not thyroid receptor ${\beta}$, glucocorticoid receptor, or estrogen receptor ${\beta}$. We also found that AR interacted with RanBPM in both the absence and presence of testosterone (T). Furthermore, we discovered that STC2 recruits RanBPM/AR complex in T-dependent manner. Taken together, our findings suggest that STC2 is a novel RanBPM-interacting protein that promotes AR transactivation.

• The Magazine of the IEIE
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• v.29 no.5
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• pp.19-31
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• 2002

본 논문은 IP 기술의 발전과 보급에 따라 활발히 논의되고 있는 이동통신망에서의 IP 기반 RAN 기술에 대해 기술한다. 먼저 IP 기반 RAN에서 IP 전송을 위해 고려되어야 하는 주요 기술 내용에 대해 알아보고 RAN이 가지는 단점을 극복하기 위한 OpenRAN 구조에 대해 고찰하면서 현재 여러 기관에서 제안하고 있는 IP 기반 RAN 구조에 대해 살펴본다.

• Information and Communications Magazine
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• v.31 no.3
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• pp.79-84
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• 2014

무선 통신 데이터 사용량은 꾸준히 증가하고 있는데, 주파수 자원이 한정되어 있어서 무선 통신망의 용량을 키우려면 셀(cell)을 작게 하여 동일 면적에 더 많은 셀을 구축해야 한다. 이를 효율적으로 구축하기 위한 방안으로 C-RAN 개념이 도입되었다. 본고에서는 C-RAN 아키텍쳐에 대해 소개하고, C-RAN의 특장점을 성능 관점, 설치 운용 관점 및 3GPP Release 10 이후의 기술 적용 관점에서 살펴보고, Super Hot Spot에서의 C-RAN 응용 사례와 향후 발전 전망에 대해 논의한다.

• Molecules and Cells
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• v.40 no.4
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• pp.271-279
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• 2017

Ran-binding protein family member, RanBP9 has been reported in various basic cellular mechanisms and neuropathological conditions including schizophrenia. Previous studies have reported that RanBP9 is highly expressed in the mammalian brain and retina; however, the role of RanBP9 in retinal development is largely unknown. Here, we present the novel and regulatory roles of RanBP9 in retinal development of a vertebrate animal model, zebrafish. Zebrafish embryos exhibited abundant expression of ranbp9 in developing brain tissues as well as in the developing retina. Yeast two-hybrid screening demonstrated the interaction of RanBP9 with Mind bomb, a component of Notch signaling involved in both neurogenesis and neural disease autism. The interaction is further substantiated by co-localization studies in cultured cells. Knockdown of ranbp9 resulted in retinal dysplasia with defective proliferation of retinal cells, downregulation of neuronal differentiation marker huC, elevation of neural proliferation marker her4, and alteration of cell cycle marker p57kip2. Expression of the $M{\ddot{u}}ller$ glial cell marker glutamine synthase was also affected in knockdown morphants. Our results suggest that Mind bomb-binding partner RanBP9 plays a role during retinal cell development of zebrafish embryogenesis.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.42 no.2
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• pp.358-365
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• 2017

In order for developing countries to design and deploy Long Term Evolution (LTE) network in a cost-efficient manner, the differentiated way of technological design and deployment methods are necessary as compared to those for advanced countries. This paper focused on Radio Access Network (RAN) design methodology for developing countries that consists of major part of the network cost. To verify the effectiveness of the suggested design methodology, a Korean telecom company A's actual design experience in an African developing country was examined.