• 무역상무연구
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• 제25권
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• pp.211-241
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• 2005

Innovation resistance toward technology products such as e-Marketplace is an important concept in business to business marketing. But most of researches and literatures have not been focused on innovation resistance. Therefore, the objective of this paper is to confirm key factors that effects on the innovation resistance. Additionally this study will be revealed the factors affecting the innovation resistance to information technology of trade according to adopting stage. Based on the past literatures, the innovation resistance of users can be viewed as dependent on two sets of factors came from the study of Innovation Resistance Model(Ram, 1987):perceived innovation(e-Marketplace) characteristics and user(trading company) characteristics. Perceived innovation characteristics consists of relative advantage, compatibility, perceived risk, complexity, inhibitory effect on the adoption of profitable innovation. The user characteristics consist of innovativeness, beliefs and attitude toward existing trade method. And user adoption stage came from the study of Innovation Diffusion(Roger, 1995). To make it simple, this study divides group1(knowledge/persuasion/decision) and group2(implementation/confirmation). In the result of the empirical study, the hypothesis 1, hypothesis 2, hypothesis 4 were supported partially and hypothesis 3 was completely supported.

• 한국인쇄학회지
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• 제29권2호
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• pp.15-32
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• 2011

In printing, managing color means that how closely its color reproducts and printing supplier meets customers' requirements. When applying device profiles, it depends on properties of the devices. But color management of domestic digital prints is accomplished more scientifically and objectively than any other printing. According to this paper addresses a method of evaluating between proof prints and offset prints which are produced by identical date on the field. We evaluate two cases normal proof prints and domestic offset prints based on standardized color data analysis and subjective data analysis. We gathered objective data by measuring solid density, $CIEL^*a^*b^*$ and ${\Delta}E^{*_}{ab}$. Furthermore, we evaluated the offset prints and proof prints through human eyes to decide the ranking.

• 한국임상약학회지
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• 제26권2호
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• pp.181-186
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• 2016

Background: There has been on increasing emphasis on the importance of monitoring the safety of participants in a clinical trial to protect patients and maintain the integrity of the trial. The independent data monitoring committee (IDMC) has become common component of randomized clinical trials in recent years. Methods: It is important to consider the implications of different approaches that are being used in various countries. IDMC guidelines in Korea, US, and Europe were reviewed and compared to provide the objective, composition and operation of IDMC in detail. Results: IDMC is a group of experts in related subject are as who perform interim data monitoring to make a recommendation to the sponsor or organizer regarding appropriateness of trial continuation and the need for modifications of the trial. Independence of IDMC is preferred in order to minimize influence of factors unrelated to scientific, medical and ethical considerations that should underlie decision-making. Conclusion: IDMC has become an increasingly important component of clinical trials in recent years. Practical operating procedures need to be developed considering the future regulatory status of data monitoring committees.

• 한방안이비인후피부과학회지
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• 제17권3호
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• pp.95-101
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• 2004

Objective: The purpose of this study is to investigate the past history of the patients with peripheral type nerve palalysis. Methods: We examined the age, sex, region, month, season, past disease and cause of 692(343 male, 349 female) patients with peripheral type nerve palalysis who visited Dept. of Acupuncture and Moxibustion, Bundang Oriental Medicine Hospital, Dongguk University, from 2001-10-1 to 2004-9-30. Results: 420 patiens(60.7$\%$) were in the age between 30-59. The region, sex, and seasonal distribution didn't have a remarkable contrasts. In the past disease, Hypertension(14.5$\%$), Diabets mellitus(9.2$\%$), Gastric diseases(3.9$\%$) and Live diseases(3.8$\%$) were investigated highly than other diseases. In the distribution of cause, fatigue(36.3$\%$), unknown(34.8$\%$), stress(19.2$\%$) cold exposure(12.1$\%$) were investigated highly than other causes.

• 한국농촌건축학회논문집
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• 제14권2호
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• pp.35-42
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• 2012

This research intends to find the concept of eco-village in suburban area which various people can experience. For this, we established general ideas through theoretical reflections, and found an objective of suburban eco-village through functional practices. According to the research, a composition of eco-village to reduce the environmental load consists of three major functions. First, by forming traditional meanings of eco-village community, it creates eco-friendly life through energy saving and resource recycling. Second, it functions as relieving the stress of the urbanites and healing their mind and body in the nature of formed eco-village community. Finally, the implementation of eco-village is an idea of group of people who tends to live with nature. Thus, by recovering the nature and by preserving the nature with eco-friendly concept, it will be developed by a place where people can experience the importance of nature. However, these three functions should reflect regional characteristics sufficiently, and through saving and utilizing the history, culture and ecological resources of the regions, it gives positive support to local natives' sustainable life. Consequently, it will show the right direction of development of suburban eco-village through each case analysis of these three functions.

• 대한건축학회논문집:구조계
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• 제36권2호
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• pp.155-163
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• 2020

Indoor airborne particles are consisted of outdoor- and indoor-generated particles, which can be characterized by their compositions, generation features and toxicity. The identification of source contribution of indoor and outdoor origin to indoor particles is important to understand PM_2.5 transport in a building as well as its impact on occupant health. The objective of this study is to investigate seasonal source contribution to indoor PM_2.5 concentration depending on airtightness of apartment units. To evaluate the source contribution, particle transport including penetration, generation, exfiltration in an apartment housing unit was simulated by using CONTAM with particle and airflow simulation parameters obtained from field measurements. The result showed that the outdoor source contribution to indoor air was relatively dominant in the leaky housing unit during spring (77.2%) and winter (73.9%), and the indoor source was dominant in the airtight housing unit during summer (60.3%) and fall (60.7%). These results indicate the seasonal health risk of indoor PM_2.5 can be varied according to airtightness of apartment units.

• 공업화학
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• 제34권1호
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• pp.75-79
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• 2023

The International Maritime Organization (IMO) Marine Environmental Protection Committee (MEPC) may adopt actions after completing impact assessments and reviewing results in accordance with the original strategy and impact assessment procedure (MEPC.1/Circ.885). The assessment of the impact of greenhouse gas (GHG) reduction measures is an important step in determining whether to implement GHG regulations. This study identifies and proposes improvements in the impact assessment procedure for future mid- and long-term measures. Improvements for future measures should start with a review of "the procedure for assessing impacts on states of candidate measures" and "the actual process of the comprehensive impact assessment for short-term measures in 2021." The procedural improvements were largely derived from the order and period of task performance, the clear definition of terms, and the review of task results through lessons learned, analysis, and expert workshops. The impact assessment of future mid- and long-term measures should be procedurally improved to ensure uniformity and consistency, which will provide objective results for Member States and industries to help smooth the adoption of measures.

• 한국운동역학회지
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• 제33권4호
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• pp.128-136
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• 2023

Objective: The aim of this study was to investigate the effect of an 8-week closed kinetic chain typed Reformer and Chair Pilates exercise on static and dynamic lower limb alignment for healthy female adults. Method: Ten healthy young female adults without musculoskeletal injury history in last 6 months (Age: 29.3 ± 3.5 yrs., Height: 165 ± 3.4 cm, Body mass: 58.2 ± 5.4 kg) participated in this study. All participants asked to join the 8-week closed kinetic chain typed Reformer and Chair Pilates exercise, and the program was conducted for 60 minutes twice a week. Participants were asked to be measure a static Q-angle and performed free squat one week before and after the program. A 3-D motion analysis with 8 infrared cameras and 5 channels of EMG was executed in this study. The effectiveness of the training was evaluated by paired t-test, and the significance level was set at .05. Results: A significantly decreased in internal rotation angles was found at hip joint during free squat after the training. Also, significantly decreased in lateral rotation angles were found at knee and ankle joint during free squat after training. Finally, significantly decreased in muscle activations were found at adductor longus and peroneus longus during free squat after training. Conclusion: From results of our study, it is concluded that an 8-week closed kinetic chain typed Pilates exercise positively effect on lower limb alignment during dynamic movement.

• 대한한방소아과학회지
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• 제38권1호
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• pp.1-9
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• 2024

Objective The purpose of this study was to confirm the effects of Galgeunhwanggeumhwangryeon-tang (PSCG) extract on skin moisturizing, antibacterial, and tight junction recovery in atopic dermatitis-induced mice. Methods In this study, we used 4-week-old NC/Nga mice divided into four groups: control (Ctrl), lipid barrier elimination (LBE), dexamethasone (Dx) after lipid barrier elimination (DEX), and PSCG after lipid barrier elimination (PSC). Ten rats were assigned to each treatment group. Three days after drug administration following lipid barrier elimination, ceramide kinase, caspase 14, sodium hydrogen antiporter (NHE), cathelicidin, claudin, and toll-like receptor (TLR)-2 were observed to confirm the restoration of skin moisturizer production, antimicrobial barriers, and tight junctions in the skin barrier. Results Ceramide kinase and caspase 14 positive reaction were significantly higher in PSC than in LBE and DEX. Both NHE and cathelicidin showed higher positive reactions in PSC than in LBE and DEX. Claudin, and TLR-2 showed higher levels of positive staining in the PSC group than in the LBE and DEX groups. Conclusion It was confirmed that the PSCG extract can have the potential to restore the damaged skin barrier in atopic dermatitis.

• Clinical and Experimental Vaccine Research
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• 제12권3호
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• pp.193-208
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• 2023

One of the most significant medical advancements in human history is the development of vaccines. Progress in vaccine development has always been greatly influenced by scientific human innovation. The main objective of vaccine development would be to acquire sufficient evidence of vaccine effectiveness, immunogenicity, safety, and/or quality to support requests for marketing approval. Vaccines are biological products that enhance the body's defenses against infectious diseases. From the first smallpox vaccine to the latest notable coronavirus disease 2019 nasal vaccine, India has come a long way. The development of numerous vaccines, driven by scientific innovation and advancement, combined with researcher's knowledge, has helped to reduce the global burden of disease and mortality rates. The Drugs and Cosmetics Rules of 1945 and the New Drugs and Clinical Trials Rules of 2019 specify the requirements and guidelines for CMC (chemistry, manufacturing, and controls) for all manufactured and imported vaccines, including those against coronavirus infections. This article provides an overview of the regulation pertaining to the development process, registration, and approval procedures for vaccines, particularly in India, along with their brief history.