• 대한화학회지
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• 제57권6호
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• pp.744-754
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• 2013

Quantitative structure-activity relationship (QSAR) analysis for recently synthesized imidazole-(benz)azole and imidazole - piperazine derivatives was studied for their anticancer activities against breast (MCF-7) cell lines. The statistically significant 2D-QSAR models ($r^2=0.8901$; $q^2=0.8130$; F test = 36.4635; $r^2$ se = 0.1696; $q^2$ se = 0.12212; pred_$r^2=0.4229$; pred_$r^2$ se = 0.4606 and $r^2=0.8763$; $q^2=0.7617$; F test = 31.8737; $r^2$ se = 0.1951; $q^2$ se = 0.2708; pred_$r^2=0.4386$; pred_$r^2$ se = 0.3950) were developed using molecular design suite (VLifeMDS 4.2). The study was performed with 18 compounds (data set) using random selection and manual selection methods used for the division of the data set into training and test set. Multiple linear regression (MLR) methodology with stepwise (SW) forward-backward variable selection method was used for building the QSAR models. The results of the 2D-QSAR models were further compared with 3D-QSAR models generated by kNN-MFA, (k-Nearest Neighbor Molecular Field Analysis) investigating the substitutional requirements for the favorable anticancer activity. The results derived may be useful in further designing novel imidazole-(benz)azole and imidazole-piperazine derivatives against breast (MCF-7) cell lines prior to synthesis.

• 설비공학논문집
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• 제15권9호
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• pp.744-750
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• 2003

The performance of adiabatic capillary tubes are measured to provide the database for a generalized correlation. Test conditions and capillary tube geometries are selected to cover a wide range typically observed in air-conditioning and heat pump applications. Based on extensive experimental data for R22, R290, and R407C measured in this study, a generalized correlation for refrigerant flow rate in adiabatic capillary tubes is developed by implementing dimensionless parameters for tube inlet conditions, capillary tube geometry, and refrigerant properties. The correlation yields good agreement with the present data for R22, R290, and R407C with average and standard deviations of 0.9% and 5.0%, respectively. In addition, approximately 97% of the data for Rl2, R134a, R152a, R410A, and R600a obtained in the open literature are correlated within a relative deviation of $\pm$ 15%.

• 한국식품과학회지
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• 제47권6호
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• pp.744-750
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• 2015

Purple sweet potatoes were dehydrated with maltodextrin with different dextrose equivalent (DE) values of 4-7, 13-17, 16.5-19.5, and 17-20. Maltodextrin was used as a molecular press dehydrating agent. The molecular dehydration rate of the purple sweet potatoes increased over time. As the DE of maltodextrin increased, the moisture content after 12 h of dehydration decreased from 65.7% to 40.8, 36.1, 34.9, and 28.6% for DE values of 4-7, 13-17, 16.5-17.5, and 17-20, respectively. Additionally, total phenolic content, anthocyanin, and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activities decreased as the DE value of maltodextrin increased. While maltodextrins with DE values of 16.5-19.5 and 17-20 effectively dehydrated the purple sweet potatoes, total phenolic, anthocyanin, and DPPH radical scavenging activities were lowered during dehydration. The DPPH radical scavenging activities correlated to both the total phenolic content ($r^2=0.96$) and anthocyanin contents ($r^2=0.95$) of the purple sweet potatoes. These results indicate that the purple sweet potatoes were effectively dehydrated with maltodextrin whose DE values ranged 16.5-20, although there were losses in the total phenolic and anthocyanin contents.

• Journal of Advanced Marine Engineering and Technology
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• 제29권5호
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• pp.526-532
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• 2005

The cooling heat transfer coefficient of $CO_2$(R-744) in a horizontal tube was investigated experimentally. The experiments were conducted without oil in a closed refrigerant loop which was driven by a magnetic gear pump. The main components of the refrigerant loop are a receiver, a variable-speed pump. a mass flow meter. a pre-heater and gas cooler(test section). The test section consists of a smooth, horizontal stainless steel tube of 7.75 mm inner diameter. The experiments were conducted at mass flux of 200 to $400\;kg/m^{2}s$ and the inlet cooling pressure of 7.5 MPa to 10.0 MPa. The variation of heat transfer coefficient tends to decrease as cooling pressure of $CO_2$ increases. The heat transfer coefficient with respect to mass flux increases as mass flux increases. The pressure drop of $CO_2$ in the gas cooler shows a relatively good agreement with that predicted by Blasius's correlation. The local heat transfer coefficient of $CO_2$ agrees well with the correlation by Bringer-Smith.

• 한국지열·수열에너지학회논문집
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• 제8권2호
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• pp.48-54
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• 2012

To analyze the cooling performance of fin-tube evaporator in the refrigerator truck using R744 according to frost growth, the analytical model of evaporator was developed under frost and non-frost conditions. The performance of fin-tube evaporator was investigated with frost thickness and indoor temperature. Besides, the performance of evaporator under frost condition was compared to that under non-frost condition. As a result, area of air passage and system performance were decreased as the frost thickness increased. The cooling capacity was reduced by 10%, 20%, 30% when the frost thickness was 0.7 mm, 1.1 mm, and 1.6 mm respectively. At these conditions, the block ratio was 31%, 48%, and 71%. In addition, the outlet quality of refrigerant was not over 1 when the frost thickness was 1.6 mm in spite of high indoor air temperature.

• 한국태양에너지학회 논문집
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• 제34권4호
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• pp.51-56
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• 2014

In this paper, OTEC(Ocean Thermal Energy Conversion) system with vapor-vapor ejector is newly proposed. And 6 wet refrigerants are applied into the proposed OTEC system for performance comparison. The results of comparison performance are as follows. In the view of system efficiency, R32/R744(90:10) has the highest efficiency among the 6 refrigerants. In case of evaporation capacity, pump work and mass flow rate of working fluid, R744, R717 and R717 is lowest value, respectively. As this results, the vapor-vapor ejector is able to increase the efficiency of system. And It is necessary to select the optimized working fluid considering environmental and economic factors.

• 한국물환경학회지
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• 제33권6호
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• pp.744-753
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• 2017

The sediment delivery ratio (SDR) is widely used to estimate sediment loads by multiplying soil loss through the Revised Universal Equation (RUSLE). In this study, the SDR equation was developed for the Lake Imha watershed using soil loss calculated by RUSLE and sediment loads by the calibrated Hydrological Simulation. Program Fortran (HSPF). The ratio of watershed relief and channel length ($R_f/L_{ch}$), the ratio of watershed relief and watershed length ($R_f/L_b$), curve number (CN), area (A), and channel slope ($SLP_{ch}$) demonstrated strong correlations with SDR. SDR equations were developed by a combination of subwatershed parameters by referring to the correlation analysis. The area based power functional SDR developed in this study showed significant errors at the point right after entering major tributaries, because SDR was unrealistically reduced when the watershed area increased significantly. The $SLP_{ch}$-based power functional SDR also showed extraordinary values when the channel slope was gradual. The SDR equation that showed the highest value of the coefficient of determination also presented unrealistic changes in the sediment loads within a relatively short river distance. The SDR equation $SDR=0.0003A^{0.198}R_f/L{_w}^{1.167}$ was recommended for application to the Lake Imha watershed. Using this equation, sediment loads at the outlet of the Lake Imha watershed were calculated, and the HSPF parameters related to sediment in the uncalibrated subwatersheds were determined by referring to the sediment loads calculated with the SDR equation.

• 대한화장품학회지
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• 제31권1호
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• pp.91-96
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• 2005

일련의 alkyl-3,4-dihydroxybenzoate (A)와 N-alkyl-3,4-dihydroxybenzamide (B) 유도체들의 치환기(R1 및 R2) 변화에 따른 피부 감작성과의 관계를 HQSTR 방법으로 분석하였다. 유도된 피부 감작성에 관한 HQSTR 모델은 매우 양호한 예측성(cross-validated $r^2_{cv}.,\;q^2=0.744$)과 적합성(non-cross-validated, $r^2_{ncv}$. =0.978)을 나타내었다. 이들 두 화합물은 멜라닌 생성 저해 활성이 클수록 피부 감작성이 낮은 반비례적인 경향을 보였으며 R1-치환기 사슬 중 C1 ${\~}$ C3 원자 부분은 피부 감작성에 기여하지 않는 경향을 나타내었다. 따라서 ester (A)는 amide (B)보다 피부 감작성이 낮으나(AB) 특징을 나타내므로 미백제의 활성 성분으로서 매우 이상적인 화합물임을 알았다.

• 한국식품과학회지
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• 제53권1호
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• pp.63-71
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• 2021

In this study, a comparative analysis was carried out between the 'Beta Tiny' and 'TY Nonari' cherry tomato cultivars harvested at the pink and red stages. Samples of the red stage were stored at room temperature for 9 days, during which physicochemical qualities, antioxidant compounds, and activities were measured. As cherry tomato ripening and storage progressed, firmness was reduced, whereas the lycopene content increased. Total phenolic content and antioxidant activity showed no significant changes as ripening and storage progressed; however, total flavonoid content of 'Beta Tiny' showed a significant increase (p<0.05). The main polyphenols in the two cultivars were identified as chlorogenic acid, rutin, and (-)-epigallocatechin gallate, among which chlorogenic acid showed a significant decrease (p<0.05) as ripening and storage progressed. A strong correlation was found between total phenolic and flavonoid content (R=0.744), and ABTS radical scavenging activity (R=0.975). Additionally, a negative correlation was shown by lycopene and chlorogenic acid (R= -0.934).

• 한국전기전자재료학회논문지
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• 제19권8호
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• pp.744-748
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• 2006

Emission characteristics of terbium-activated $InBO_3$ under cathode-ray(c.r.) and vacuum ultra violet(v.u.v.) irradiation have been investigated as a functions of norminal compositions and firing conditions. From the x-ray analysis, it was found that some of the synthesized samples contained excess $In_2O_3$ and the amount of the excess $In_2O_3$ varied with the norminal composition and heat treatment conditions. The samples with remanent excess $In_2O_3$ showed lower luminescence intensities than the ones free of excess $In_2O_3$. The phosphors of norminal composition of $InBO_3+10mol%B_2O_3:2mol%Tb$ synthesized at $1250^{\circ}C$ showed excellent CL and PL properties.