• Title/Summary/Keyword: R-Pilot

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A Pilot Study of Herb Medication for Atopic Dermatitis (한약의 아토피 피부염 치료에 대한 예비 임상 연구)

  • Lim, Young-Kwon;Jung, Ji-A;Yun, Cheol-Sang;Hur, Kwang-Wook;Lee, Hun;Kim, Ho-Chyul;Kim, Young-Ran;Cho, Yun-Hi
    • The Journal of Pediatrics of Korean Medicine
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    • v.20 no.3
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    • pp.129-141
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    • 2006
  • Objectives : The purpose of this study is to determine clinical efficacy of herbal medicine by evaluating SCORAD Index and total level of ceramaides in the skin of 13 children with atopic dermatitis Methods : Subjects are divided into two groups : Group 1(non-differentiation children treated with Saenghyeoryunbueom) and group 2(differentiation children treated with either pyungwisan, onchungum or gamitongsungsan). We determine SCORAD Index and total level of ceramaides in the skin of 13 children with atopic dermatitis before and after taking each of herbal treatment for 12 weeks. Results : After herbal prescription for 12 weeks, A SCORAD index of both group 1 and group 2 was decreased. However, the total level of ceramides in group 1 and group 2 was not altered after 12 weeks. When the correlation between the alteration of SCORAD index and ceramides levels was determined, the SCORAD index in group 1 was inversely correlated with the total level of ceramides(r=-0.994, p=0.006) In contrast, the alteration of SCORAD index in group 2 was not correlated with ceramide levels. Conclusions : The clinical efficacy of Saenghyeoryunbueom for non-differentiation children with atopic dermatitis is paralleled with the increased level of ceramides in skin. The clinical efficacy of pyungwisan, onchungum or gamitongsungsan for differentiation children with atopic dermatitis is not correlated with ceramide level in skin.

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Comparison of Infiltration Induced in Veins of Rabbit's Ear and Human's Forearm by Using Bioelectrical Impedance: Pilot Study

  • Kim, Jae-Hyung;Hwang, Young-Jun;Kim, Gun-Ho;Shin, Beum-Joo;Kim, Yong-Jin;Lee, Eun-Joo;Jeon, Gye-Rok
    • Journal of Sensor Science and Technology
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    • v.26 no.5
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    • pp.306-313
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    • 2017
  • An early detection of infiltration in veins is essential to minimize the injuries caused during infusion therapy, which is one of the most important tasks for nurses in clinical settings. We report that bioelectrical impedance analysis is useful in the early detection of infiltration at puncture sites. When infiltration was intentionally induced in the vein of a rabbit's ear, impedance parameters showed significant difference before and after infiltration. In particular, the relative resistance at 20 kHz in the vein of rabbit's ear reduced largely at infiltration, decreased slowly, and then stayed at a constant value. This indicates that the vein in the ear of the rabbit is small, and hence the infiltrated intravenous (IV) solution no longer accumulates after 3 minutes of infiltration. However, when infiltration was induced in the vein of a human's forearm, the relative resistance at 20 kHz decreased gradually over time. In the $R-X_c$ graph, the positions in infiltration induced in the rabbit's ear rapidly shifted before and after infiltration whereas the positions in infiltration induced in the human's forearm changed gradually during infiltration. Our findings suggest that bioelectrical impedance analysis is an effective method to detect the infiltration early in a noninvasive and quantitative manners.

Investigation of geosmin removal efficiency by microorganism isolated from biological activated carbon (생물활성탄에서 분리한 미생물의 지오스민 제거효율 평가)

  • Baek, Dawoon;Lim, Jaewon;Cho, Yoonjung;Ahn, Yong-Tae;Lee, Hyeyoung;Park, Donghee;Jung, Dongju;Kim, Tae-Ue
    • Journal of Korean Society of Water and Wastewater
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    • v.29 no.1
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    • pp.47-55
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    • 2015
  • Recently, the production of taste and odor (T&O) compounds is a common problem in water industry. Geosmin is one of the T&O components in drinking water. However, geosmin is hardly eliminated through the conventional water treatment systems. Among various advanced processes capable of removing geosmin, adsorption process using granular activated carbon (GAC) is the most commonly used process. As time passes, however GAC process changes into biological activated carbon (BAC) process. There is little information on the BAC process in the literature. In this study, we isolated and identified microorganisms existing within various BAC processes. The microbial concentrations of BAC processes examined were $3.5{\times}10^5$ colony forming units (CFU/g), $2.2{\times}10^6CFU/g$ and $7.0{\times}10^5CFU/g$ in the Seongnam plant, Goyang plant and Goryeong pilot plant, respectively. The dominant bacterial species were found to be Bradyrhizobium japonicum, Novosphingobium rosa and Afipia broomeae in each plants. Removal efficiencies of $3{\mu}g/L$ geosmin by the dominant species were 36.1%, 36.5% and 34.3% in mineral salts medium(MSM) where geosmin was a sole carbon source.

Design of a Rod-Type Aspheric Lens Collimator for Optical Telecommunication (막대 형태의 비구면 렌즈를 이용한 광통신용 시준기의 설계)

  • Kang, Seok-Bong;Kang, Eun-Kyoung;HwangBo, Chang-Kwon;Kang, Sang-Do;Kim, Jong-Sup
    • Korean Journal of Optics and Photonics
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    • v.19 no.1
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    • pp.31-35
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    • 2008
  • A rod-type aspheric lens collimator for the optical telecommunication system which shows high coupling efficiency and experiences small coupling loss for misalignment errors is designed. The working distance, thickness, and diameter of the rod-type aspheric lens are determined to be close to those of the GRIN lens collimator in order to replace the GRIN lens with the rod-type aspheric lens. Since the coupling loss mainly originated from the spherical aberration of the lens, the spherical aberration in the rod-type aspheric lens is reduced drastically, and it turns out that the coupling efficiency of the rod-type aspheric lens collimator is higher than that of the available collimators, such as ball lens, GRIN lens, and C-type lens collimators.

Comparing the Effect of Three Processing Methods for Modification of Filament Yarns with Inorganic Nanocomposite Filler and their Bioactivity against Staphylococcus aureus

  • Dastjerdi, Roya;Mojtahedi, M.R.M.;Shoshtari, A.M.
    • Macromolecular Research
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    • v.17 no.6
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    • pp.378-387
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    • 2009
  • This research compared three methods for producing and processing nanocomposite polypropylene filament yarns with permanent antimicrobial efficiency. The three methods used to mix antimicrobial agents based on silver nano particles with PP were as follows: 1) mixing of PP powder and inorganic nanocomposite filler with the appropriate concentration using a twin-screw extruder and preparing granules, 2) method 1 with a singlerather than twin-screw extruder, and 3) producing the masterbatch by a twin-screw extruder and blending it with PP in the melt spinning process. All pure polypropylene samples and other combined samples had an acceptable spinnability at the spinning temperature of $240^{\circ}C$ and take-up speed of 2,000 m/min. After producing as-spun filament yarns by a pilot plant, melt spinning machine, the samples were drawn, textured and finally weft knitted. The physical and structural properties (e.g., linear density, tenacity, breaking elongation, initial modulus, rupture work, shrinkage and crystallinity) of the as-spun and drawn yarns with constant and variable draw ratios (the variable draw ratio was used to gain a constant breaking elongation of 50%) were investigated and compared, while DSC, SEM and FTIR techniques were used to characterize the samples. Finally, the antibacterial efficiency of the knitted samples was evaluated. The experimental results revealed that the crystallinity reduction of the as-spun yarn obtained from method 1 (5%) was more than that of method 2 (3%), while the crystallinity of the modified as-spun yarns obtained with method 3 remained unchanged compared to pure yarn. However, the drawing procedure compensated for this difference. By applying methods 2 and 3, the drawing generally improved the tenacity and modulus of the modified fibers, whereas method 1 degraded the constant draw ratio. Although the biostatic efficiency of the nanocomposite yarns was excellent with all three methods, the modified fabrics obtained from methods 1 and 2 showed a higher bioactivity.

Feasibility Study for Detecting the Tropopause Folding Turbulence Using COMS Geostationary Satellite (천리안 위성 자료를 이용한 대류권계면 접힘 난류 탐지 가능성 연구)

  • Kim, Mijeong;Kim, Jae Hwan
    • Atmosphere
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    • v.27 no.2
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    • pp.119-131
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    • 2017
  • We present and discuss the Tropopause Folding Turbulence Detection (TFTD) algorithm for the Korean Communication, Ocean, Meteorological Satellite (COMS) which is originally developed for the Tropopause Folding Turbulence Product (TFTP) from the Geostationary Operational Environmental Satellite (GOES)-R. The TFTD algorithm assumes that the tropopause folding is linked to the Clear Air Turbulence (CAT), and thereby the tropopause folding areas are detected from the rapid spatial gradients of the upper tropospheric specific humidity. The Layer Averaged Specific Humidity (LASH) is used to represent the upper tropospheric specific humidity calculated using COMS $6.7{\mu}m$ water vapor channel and ERA-interim reanalysis temperature at 300, 400, and 500 hPa. The comparison of LASH with the numerical model specific humidity shows a strong negative correlation of 80% or more. We apply the single threshold, which is determined from sensitivity analysis, for cloud-clearing to overcome strong gradient of LASH at the edge of clouds. The tropopause break lines are detected from the location of strong LASH-gradient using the Canny edge detection based on the image processing technique. The tropopause folding area is defined by expanding the break lines by 2-degree positive gradient direction. The validations of COMS TFTD is performed with Pilot Reports (PIREPs) filtered out Convective Induced Turbulence (CIT) from Dec 2013 to Nov 2014 over the South Korea. The score test shows 0.49 PODy (Probability of Detection 'Yes') and 0.64 PODn (Probability of Detection 'No'). Low POD results from various kinds of CAT reported from PIREPs and the characteristics of high sensitivity in edge detection algorithm.

A Cellulolytic and Xylanolytic Enzyme Complex from an Alkalothermoanaerobacterium, Tepidimicrobium xylanilyticum BT14

  • Phitsuwan, Paripok;Tachaapaikoon, Chakrit;Kosugi, Akihiko;Mori, Yutaka;Kyu, Khin Lay;Ratanakhanokchai, Khanok
    • Journal of Microbiology and Biotechnology
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    • v.20 no.5
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    • pp.893-903
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    • 2010
  • A cellulolytic and xylanolytic enzyme complex-producing alkalothermoanaerobacterium strain, Tepidimicrobium xylanilyticum BT14, is described. The cell was Grampositive, rod-shaped, and endospore-forming. Based on 16S rRNA gene analysis and various lines of biochemical and physiological properties, the strain BT14 is a new member of the genus Tepidimicrobium. The strain BT14 cells had the ability to bind to Avicel, xylan, and corn hull. The pH and temperature optima for growth were 9.0 and $60^{\circ}C$, respectively. The strain BT14 was able to use a variety of carbon sources. When the bacterium was grown on corn hulls under an anaerobic condition, a cellulolytic and xylanolytic enzyme complex was produced. Crude enzyme containing cellulase and xylanase of the strain BT14 was active in broad ranges of pH and temperature. The optimum conditions for cellulase and xylanase activities were pH 8.0 and 9.0 at $60^{\circ}C$, respectively. The crude enzyme had the ability to bind to Avicel and xylan. The analysis of native-PAGE and native-zymograms indicated the cellulosebinding protein showing both cellulase and xylanase activities, whereas SDS-PAGE zymograms showed 4 bands of cellulases and 5 bands of xylanases. Evidence of a cohesinlike amino acid sequence seemed to indicate that the protein complex shared a direct relationship with the cellulosome of Clostridium thermocellum. The crude enzyme from the strain BT14 showed effective degradation of plant biomass. When grown on corn hulls at pH 9.0 and $60^{\circ}C$ under anaerobic conditions, the strain BT14 produced ethanol and acetate as the main fermentation products.

Heart rate monitoring and predictability of diabetes using ballistocardiogram(pilot study) (심탄도를 이용한 연속적인 심박수 모니터링 및 당뇨 예측 가능성 연구(파일럿연구))

  • Choi, Sang-Ki;Lee, Geo-Lyong
    • Journal of Digital Convergence
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    • v.18 no.8
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    • pp.231-242
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    • 2020
  • The thesis presents a system that continuously collects the human body's physiological vital information at rest with sensors and ICT information technology and predicts diabetes using the collected information. it shows the artificial neural network machine learning method and essential basic variable values. The study method analyzed the correlation between heart rate measurements of BCG and ECG sensors in 20 DM- and 15 DM+ subjects. Artificial Neural Network (ANN) machine learning program was used to predictability of diabetes. The input variables are time domain information of HRV, heart rate, heart rate variability, respiration rate, stroke volume, minimum blood pressure, highest blood pressure, age, and sex. ANN machine learning prediction accuracy is 99.53%. Thesis needs continuous research such as diabetic prediction model by BMI information, predicting cardiac dysfunction, and sleep disorder analysis model using ANN machine learning.

DEEP-South: Photometric Study of NPA rotators 5247 Krolv and 14764 Kilauea

  • Lee, Hee-Jae;Kim, Myung-Jin;Moon, Hong-Kyu;Park, Jintae;Kim, Chun-Hwey;Choi, Young-Jun;Yim, Hong-Suh;Roh, Dong-Goo;Oh, Young-Seok
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.1
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    • pp.55.2-56
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    • 2016
  • The spin states of asteroids is regarded as an important clue to understand not only the physical property of an individual object but also the dynamical evolution of the of the population as a whole. Single asteroids can be broadly classified into two separate groups according to their rotational states; Principal Axis (PA) and Non-Principal Axis (NPA) rotators. To date, lightcurve observations have been carried out mostly for PA asteroids. However, discovery of NPA objects has recently been increased due to new observing techniques, and this is the reason why rotational properties of NPA rotators became an issue. As a DEEP-South pilot study for NPA, we selected two targets, 5247 Krolv (1982 UP6) and 14764 Kilauea (7072 P-L) considering their Principal Axis Rotation (PAR) code and visibility. Observations were made between Jan. and Feb. 2016 for 17 nights employing Korea Microlensing Telescope Network (KMTNet) 1.6 m telescopes installed at SSO and SAAO using DEEP-South TO (Target of Opportunity) mode. To obtain lightcurves, we conducted time-series photometry using Johnson-Cousins R-filter. Multi-band photometry was also made with BVRI filters at the same time, for taxonomy. Their preliminary lightcurves and approximate mineralogy will be presented.

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Direct Fabrication of a-Si:H TFT Arrays on Flexible Substrates;Principal Manufacturing Challenges and Solutions

  • O’Rourke, Shawn M.;Loy, Douglas E.;Moyer, Curt;Ageno, Scott K.;O’Brien, Barry P.;Bottesch, Dirk;Marrs, Michael;Dailey, Jeff;Bawolek, Edward J.;Trujillo, Jovan;Kaminski, Jann;Allee, David R.;Venugopal, Sameer M.;Cordova, Rita;Colaneri, Nick;Raupp, Gregory B.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08a
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    • pp.251-254
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    • 2007
  • Principal challenges to $\underline{direct\;fabrication}$ of high performance a-Si:H transistor arrays on flexible substrates include automated handling through bonding-debonding processes, substrate-compatible low temperature fabrication processes, management of dimensional instability of plastic substrates, and planarization and management of CTE mismatch for stainless steel foils. Viable solutions to address these challenges are described.

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