• 제목/요약/키워드: R statistical package

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체외수정시술시 유전자 재조합 난포자극호르몬제의 효용성 (The Efficacy of Recombinant Human Follicle Stimulating Hormone (rhFSH) in Human IVF-ET Program)

  • 한국선;이홍복;송인옥;박용석;변혜경;전진현;궁미경
    • Clinical and Experimental Reproductive Medicine
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    • 제29권1호
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    • pp.45-56
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    • 2002
  • Objectives: Recently, recombinant FSH (rFSH) has been manufactured using a Chinese hamster ovary cell line transfected with the gene encoding human FSH. Both rFSH and urinary gonadotropin (uFSH) could be used for controlled ovarian hyperstimulation (COH). However, uFSH implies a number of disadvantages, such as batch-to-batch inconsistency, no absolute source control, dependence on large amounts of urine, low specific activity, and low purity. The purpose of this study was to evaluate the efficacy of rFSH in human IVF-ET program. Materials and Methods: A total of 508 infertile women was enrolled in this study. They are classified into rFSH group (n=177) or uFSH group (n=331), and all of them were matched by age and cause of infertility in same period. The $Puregon^{(R)}$ (Organon, Holland) was used as rFSH, and the Metrodin-$HP^{(R)}$ (Serono, Switzeland) and $Humegon^{(R)}$ (Organon, Holland) was used as uFSH. We subdivided the patients into three age groups. The outcomes of IVF-ET program were analyzed using the statistical package for social sciences (SPSS). Results: There was no significant differences in the level of estradiol on hCG injection day, the numbers of retrieved oocytes, matured oocytes, fertilized oocytes, transferred embryos, frozen embryos between the two groups. The total dose (IU) of gonadotropin for COH was significantly lower in the rFSH group compared to uFSH group ($1339{\pm}5491.1$ vs $2527.8{\pm}1075.2$ IU, p<0.001). Clinical pregnancy rate per embryo transfer in the rFSH group showed increasing tendency, compared to the uFSH group, but there was no statistical significance (35.2% vs 29.3%). Our results demonstrated that the relative efficiency of rFSH compared with uFSH is higher in older patients. Conclusions: The ovarian stimulatory effect and clinical outcome of recombinant FSH was similar to that of the urinary gonadotropin. The IVF-ET cycles with significantly lower dose of gonadotropin in rFSH group showed comparable results. Therefore, we suggest that recombinant FSH is more potent and effective than urinary gonadotropin.

A tutorial on generalizing the default Bayesian t-test via posterior sampling and encompassing priors

  • Faulkenberry, Thomas J.
    • Communications for Statistical Applications and Methods
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    • 제26권2호
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    • pp.217-238
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    • 2019
  • With the advent of so-called "default" Bayesian hypothesis tests, scientists in applied fields have gained access to a powerful and principled method for testing hypotheses. However, such default tests usually come with a compromise, requiring the analyst to accept a one-size-fits-all approach to hypothesis testing. Further, such tests may not have the flexibility to test problems the scientist really cares about. In this tutorial, I demonstrate a flexible approach to generalizing one specific default test (the JZS t-test) (Rouder et al., Psychonomic Bulletin & Review, 16, 225-237, 2009) that is becoming increasingly popular in the social and behavioral sciences. The approach uses two results, the Savage-Dickey density ratio (Dickey and Lientz, 1980) and the technique of encompassing priors (Klugkist et al., Statistica Neerlandica, 59, 57-69, 2005) in combination with MCMC sampling via an easy-to-use probabilistic modeling package for R called Greta. Through a comprehensive mathematical description of the techniques as well as illustrative examples, the reader is presented with a general, flexible workflow that can be extended to solve problems relevant to his or her own work.

요양보호사의 응급상황대처능력 영향 요인 (Factors Affecting Emergency Response Ability of Caregivers)

  • 김순옥
    • 한국보건간호학회지
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    • 제36권1호
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    • pp.59-74
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    • 2022
  • Purpose: This study aimed to identify the factors affecting the emergency response ability to develop an education program to strengthen the emergency response ability of caregivers having the highest probability of discovering emergency situations. Methods: This study is a descriptive research study conducted by 204 caregivers working in elderly care facilities and home care centers located in one area. The collected data were analyzed by independent t-test, one-way analysis of variance (ANOVA), Pearson's correlation, and multiple linear regression using the Statistical Package for the Social Sciences (SPSS) 25.0 statistical program. Results: First aid knowledge was related to work time (F=3.52, p=.008), number of care people (F=2.58, p=.038), workplace (F=6.76, p=.001), and self-efficacy (F=3.70, p=.026), and the ability to cope with emergency situations showed a statistically significant difference in education level (F=3.58, p=.015). There was a positive correlation between self-efficacy and emergency response ability (r=.179, p<.05), and the factors affecting emergency response ability were education level (β=-.164, p=.050), workplace (β=.290, p=.023), and self-efficacy (β=.103, p=.022). Conclusion : Factors influencing the improvement of caregivers' ability to cope with emergency situations, workplace, education level, and self-efficacy were found. Thus, it is suggested to develop and apply an emergency education program to increase self-efficacy and consider the workplace and educational level.

환자와 병원종사자간의 의료서비스 만족도 차이분석 -종합병원을 중심으로- (Differences of Satisfaction between Patients and Hospital Employees with Medical Care Services in the General Hospital)

  • 김순재
    • 가정과삶의질연구
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    • 제17권1호
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    • pp.73-86
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    • 1999
  • The aim of this study is to suggest theoretical foundations on which hospital employees could estimate medical care services not in the position of providers but consumers. For this purpose this study compares satisfaction of providers but consumers. For this purpose this study compares satisfaction of patients with medical care service with that of hospital employees. 287 patients and 261 employees in three university hospitals in Daegu were selected as samples of investigation and asked questions. Statistical analysis was taken using SAS package. The result of this study are as follows. 1) Among the five fields of medical services patients and hospital employees have different views in doctor hospital staff(except doctor) treatment system availability service but parking service 2) Hospital employees overestimate the level of medical care services compared with patients 3) Demographical variables make a difference in medical satisfaction 4) In satisfaction-evaluation after r ceiving treatment medical system service is influential variables in both patients and hospital employees. And in patient group doctor service is following variables while availability and parking service is influential variables in employees.

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다항회귀분석을 활용한 혼합경량토의 강도산정 모델 개발 (Development of Strength Prediction Model for Lightweight Soil Using Polynomial Regression Analysis)

  • 임병권;김윤태
    • 한국해양공학회지
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    • 제26권2호
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    • pp.39-47
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    • 2012
  • The objective of this study was to develop a strength prediction model using a polynomial regression analysis based on the experimental results obtained from ninety samples. As the results of a correlation analysis between various mixing factors and unconfined compressive strength using SPSS (statistical package for the social sciences), the governing factors in the strength of lightweight soil were found to be the crumb rubber content, bottom ash content,and water-cement ratio. After selecting the governing factors affecting the strength through the correlation analysis, a strength prediction model, which consisted of the selected governing factors, was developed using the polynomial regression analysis. The strengths calculated from the proposed model were similar to those resulting from laboratory tests (R2=87.5%). Therefore, the proposed model can be used to predict the strength of lightweight mixtures with various mixing ratios without time-consuming experimental tests.

제약회사의 현금흐름이 연구개발투자에 미치는 영향 -코스닥시장을 중심으로 (Effect of Cash flow on the R&D investment of Pharmaceutical Companies - focused on KOSDAQ market)

  • 이문재;최만규
    • 한국콘텐츠학회논문지
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    • 제15권8호
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    • pp.473-480
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    • 2015
  • 본 연구는 우리나라 코스닥 제약회사를 대상으로 내 외부금융이 연구개발투자(R&D)에 미치는 영향을 분석하였다. 실증분석을 위한 표본은 2009년부터 2013년까지 상장된 기업들 중 코스닥 제약회사를 대상으로 하였으며 사용된 전체 표본은 5개년 자료로써 212개 관측치를 가진 불균형패널자료이다. 본 연구에 사용된 주요 변수들 중 개별기업 별 재무자료는 상장회사 협의회의 TS-2000, 금융감독원 전자공시 시스템의 각 기업 사업보고서, NICE신용평가정보의 KISVALUE-III 등의 자료를 통해 직접 수집하였으며, 패널분석을 위해 STATA 12.0을 사용하였다. 연구결과, 첫째 내부금융(유동비율)은 연구개발투자에 긍정적인 영향을 미쳤다. 둘째, 외부금융(부채비율)은 연구개발투자에 부정적인 영향을 미쳤다. 본 연구는 자본시장에서 정보의 비대칭으로 인해 외부금융보다 내부금융이 더 선호됨을 알 수 있다. 즉, 제약기업의 연구개발투자 활성화를 위해 내부금융의 관리 및 정부의 정책적 지원이 필요함을 보여준다.

코스닥 제약기업의 연구개발투자와 소유구조 간의 관계 (The Relationship between R&D investment and Ownership Structure in KOSDAQ Pharmaceutical Firms)

  • 이문재;최만규
    • 한국콘텐츠학회논문지
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    • 제15권6호
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    • pp.445-454
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    • 2015
  • 본 연구는 우리나라 코스닥 제약기업을 대상으로 소유구조가 제약기업의 연구개발투자(R&D)에 미치는 영향을 분석하였다. 실증분석을 위한 표본은 2000년부터 2012년까지 상장된 기업들 중 코스닥 제약기업을 대상으로 하였으며사용된 전체 표본은 13개년 자료로써 358개 관측치를 가진 불균형패널자료이다. 본 연구에 사용된 주요 변수들 중 개별기업 별 재무자료는 상장회사 협의회의 TS-2000을, 임원현황 및 주주분포 등은 금융감독원 전자공시 시스템의 각 기업 사업보고서 자료를 통해 자료를 직접 수집하였으며 기업나이, 기업크기 등은 NICE신용평가정보의 KISVALUE-III 등의 자료를 참고하였다. 연구결과, 첫째 주요주주율과 외국인투자율은 연구개발투자에 긍정적인 영향을 미쳤다. 둘째, 사외이사율은 연구개발투자에 부정적인 영향을 미쳤다. 셋째, 기관투자율은 통계적으로 유의한 결과를 미치지 못했다.

기운 일반화 t 분포를 이용한 이진 데이터 회귀 분석 (Binary regression model using skewed generalized t distributions)

  • 김미정
    • 응용통계연구
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    • 제30권5호
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    • pp.775-791
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    • 2017
  • 이진 데이터는 일상 생활에서 자주 접할 수 있는 데이터이다. 이진 데이터를 회귀 분석하는 방법으로 로지스틱(Logistic), 프로빗(Probit), Cauchit, Complementary log-log 모형이 주로 쓰이는데, 이 방법 이외에도 Liu(2004)가 제시한 t 분포를 이용한 로빗(Robit) 모형, Kim 등 (2008)에서 제시한 일반화 t-link 모형을 이용한 방법 등이 있다. 유연한 분포를 이용하면 유연한 회귀 모형이 가능해지는 점에 착안하여, 이 논문에서는 Theodossiou(1998)에서 제시된 기운 일반화 t 분포 (Skewed Generalized t Distribution)의 이용하여 우도 함수를 최대로 하는 이진 데이터 회귀 모형을 소개한다. 기운 일반화 t 분포를 R glm 함수, R sgt 패키지를 연결하여 이 논문에서 제시한 방법을 R로 분석할 수 있는 방법을 소개하고, 피마 인디언(Pima Indian) 데이터를 분석한다.

손해보험사 심사간호사의 업무수행과 직무만족 (Task performance and Job Satisfaction of Nurses in Non-life Insurance Companies)

  • 박순주
    • 간호행정학회지
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    • 제7권3호
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    • pp.487-495
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    • 2001
  • Purpose : In this study, task performance and job satisfaction of nurses in non-life insurance companies were examined to improve the personnel management in their companies. Method : Data collection was done with 119 nurses in non-life insurance companies in October and November, 1999. Data analyses were performed using SPSS Win 8.0 package. Result: The Results were as follows: 1. The tasks most commonly performed by nurses were 'medical fee inspection', 'education for staves', 'management of the injured', 'management of injury and disablement'. 2. The mean score of total job satisfaction was 3.2(interaction. 3.8; professional status, 3.6; autonomy, 3.4; task requirements, 3.1; administration, 2.8; pay and advancement, 2.6). 3. Task performance was significantly correlated with job satisfaction total score(r=0.478, p<.01). The item, 'executing statistical works and data analyses related with injury and disablement', was highly correlated with job satisfaction total score(r=0.418, p<.01). 4. The amount of task performance was significantly correlated with educational background and position. The job satisfaction level significantly correlated with personal experience and position. Conclusion : To improve the work efficiency and job satisfaction in the companies, it is necessary to set the bounds of task performance and to enlarge the promotion opportunities to higher positions.

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스포츠양말 소재의 물성 및 운동시 양말의 착용감 분석 (Physical Properties of Sports Material and Wear Trial Test of Sports Socks During Exercise)

  • 김칠순;이훈자;박명자
    • 한국의류학회지
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    • 제24권8호
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    • pp.1115-1124
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    • 2000
  • The purpose of this study was 1) to determine physical properties, and subjective evaluation of sensation of sports socks with various type of fiber content and fabric structure, and 2) to develop regression equations for predicting each sensation from physical properties of socks. Thirty healthy male students participated in the wear test with ten replications. The ANOVA, Duncans multiple test, and multiple regression, and paired-t test were used in the statistical analysis, using an SAS package. The results of this study are as follows: 1. 100% cotton socks had higher absorbency and wickability among five different socks. Comfort sensation, tactile sensation and fit sensation of socks were significantly influenced by types of fiber content. People felt that polypropylene socks were less comfortable & slightly tighter, and cotton socks were drier than the other socks. Terry socks were warmer than single jersey socks. 2. The results of the regression analysis showed that tactile sensation of socks after exercise can be predicted from the cube of moisture permeability($R^2$=0.99), and fit sensation can be predicted from drop absorbency, moisture permeability, wickability in wale and weight($R^2$=-0.98).

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